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Leveraging AlphaFold2 structural space exploration for generating drug target structures in structure-based virtual screening
Published 2025-09-01“…In contrast, with limited active compound data, a random search strategy proves more effective. Moreover, our approach is particularly promising for targets that yield poor screening results when using experimentally determined structures from the PDB. …”
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102
A neural network model enables worm tracking in challenging conditions and increases signal-to-noise ratio in phenotypic screens.
Published 2025-08-01“…Here we train a version of the DeepTangle algorithm developed for swimming worms using a combination of data derived from Tierpsy tracker and hand-annotated data for more difficult cases. …”
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103
Automated Cervical Cancer Screening Using Single-Cell Segmentation and Deep Learning: Enhanced Performance with Liquid-Based Cytology
Published 2024-11-01“…These findings demonstrate the potential of AI-powered cervical cell classification for improving CC screening, particularly with LBC. The high accuracy and efficiency of DL models combined with effective segmentation can contribute to earlier detection and more timely intervention. …”
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104
AI-Assisted Detection for Early Screening of Acute Myeloid Leukemia Using Infrared Spectra and Clinical Biochemical Reports of Blood
Published 2025-03-01“…Acute myeloid leukemia (AML) accounts for most cases of adult leukemia, and our goal is to screen out some AML from adults. In this work, we introduce an AI-enhanced system designed to facilitate early screening and diagnosis of AML among adults. …”
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105
Machine learning algorithm based on combined clinical indicators for the prediction of infertility and pregnancy loss
Published 2025-07-01“…Three methods were used for screening 100+ clinical indicators, and five machine learning algorithms were used to develop and evaluate diagnostic models based on the most relevant indicators.ResultsMultivariate analysis revealed significant differences in several factors between the patients and the control group. 25-hydroxy vitamin D3 (25OHVD3) was the factor exhibiting the most prominent difference, and most patients presented deficiency in the levels of this vitamin. 25OHVD3 is associated with blood lipids, hormones, thyroid function, human papillomavirus infection, hepatitis B infection, sedimentation rate, renal function, coagulation function, and amino acids in patients with infertility. …”
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Diagnosis of bipolar disorder based on extracted significant biomarkers using bioinformatics and machine learning algorithms
Published 2025-04-01“…One model was developed using artificial neural network and tanh functions and the other model was developed using decision tree algorithm. Practical Implications. The model developed by artificial neural network and the decision tree can be used in the diagnosis of bipolar disorder in order to screen conscripts who have this disorder with a high risk of relapse and exacerbation of symptoms.…”
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108
A monthly runoff prediction model based on ICEEMD-L-SHADE-SRU
Published 2025-12-01“…Taking the runoff data from three hydrological stations in the lower reaches of the Yellow River as an example, an improved complementary ensemble empirical mode decomposition (ICEEMD) is proposed. The runoff prediction model is established by combining the success-history adaptive differential evolution algorithm for linear population size reduction (L-SHADE) and simple recurrent unit (SRU). …”
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109
Research on Investment Estimation of Prefabricated Buildings Based on Genetic Algorithm Optimization Neural Network
Published 2025-03-01“…Starting from the investment decision-making stage of construction projects, this paper analyses the characteristics of prefabricated investment estimation and the relevant literature on the characteristics of prefabricated construction projects, uses the rough set attribute reduction algorithm to screen the key engineering characteristic factors, and establishes a BP neural network model optimized by genetic algorithm to estimate and analyze the investment of completed prefabricated construction projects. …”
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110
Potential use of saliva infrared spectra and machine learning for a minimally invasive screening test for congenital syphilis in infants
Published 2025-07-01“…This study aimed to explore the development of a method for the diagnosis of congenital syphilis using saliva FTIR spectra and machine learning algorithms in infants aged 0 to 12 months. First, the potential of FTIR for analyzing infant saliva was evaluated. …”
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111
Comparison of Deep Learning and Clinician Performance for Detecting Referable Glaucoma from Fundus Photographs in a Safety Net Population
Published 2025-07-01“…Implementation of this algorithm in screening workflows could help reallocate resources and provide more reproducible and timely glaucoma care. …”
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112
Data Mining and Analysis of the Compatibility Law of Traditional Chinese Medicines Based on FP-Growth Algorithm
Published 2021-01-01“…In terms of compatibility law of traditional Chinese antiviral prescriptions, this paper studied the compatibility law of traditional Chinese antiviral prescriptions based on the FP-growth algorithm and made exploratory research on the compatibility law information of 961 traditional classical antiviral prescriptions. …”
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113
The Development of a Brief but Comprehensive Therapeutic Assessment Protocol for the Screening and Support of Youth in the Community to Address the Youth Mental Health Crisis
Published 2024-11-01“…Objective: The objective of this study was to explore the acceptability and feasibility of a therapeutic assessment protocol for the Screening and Support of Youth (SASY). SASY provides brief but comprehensive community-based screening and support for diverse youth in the community. …”
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114
The True Shortest Path of Obstacle Grid Graph Is Solved by SGP Vertex Extraction and Filtering Algorithm
Published 2025-06-01“…Through various experiments, the shortest path length searched by the SGPVEFA proposed in this paper can be used to search for the real shortest path, and it also has advantages in comparison with recent new algorithms. With the increase in map scale and obstacle rate, the advantages of this path algorithm are more significant.…”
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115
Socially excluded employees prefer algorithmic evaluation to human assessment: The moderating role of an interdependent culture
Published 2025-05-01“…Further, this effect was mediated by perceived fairness of AI assessment, and more evident in an interdependent (but not independent) self-construal culture. …”
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116
Surrogate-assisted global and distributed local collaborative optimization algorithm for expensive constrained optimization problems
Published 2025-01-01“…Abstract This paper presents a surrogate-assisted global and distributed local collaborative optimization (SGDLCO) algorithm for expensive constrained optimization problems where two surrogate optimization phases are executed collaboratively at each generation. …”
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117
Denoising Algorithm for High-Resolution and Large-Range Phase-Sensitive SPR Imaging Based on PFA
Published 2025-07-01“…The algorithm demonstrates 57% instrumental noise reduction and achieves 1.51 × 10<sup>−6</sup> RIU resolution (1.333–1.393 RIU range). …”
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118
DATA MINING ALGORITHMS FOR PREDICTION OF STUDENT TEACHERS’ PERFORMANCE IN ICT: A SYSTEMATIC LITERATURE REVIEW
Published 2023-09-01“…On November 6, 2022, about 196 scholarly articles were downloaded from three digital libraries: Science Direct (38), ACM Digital Library (72), IEEE Xplore (51), and 35 from the Google Scholar search engine. After screening and eligibility checking, 28 scholarly articles were selected and analysed through content analysis in terms of the most commonly used algorithms, the year of publication, the study purposes, and the accuracy performance metrics. …”
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Cystic Fibrosis Newborn Screening: A Systematic Review-Driven Consensus Guideline from the United States Cystic Fibrosis Foundation
Published 2025-04-01“…Systematic reviews were used to develop seven recommendations for newborn screening program practices to improve timeliness, sensitivity, and equity in diagnosing infants with CF: (1) The CF Foundation recommends the use of a floating immunoreactive trypsinogen (IRT) cutoff over a fixed IRT cutoff; (2) The CF Foundation recommends using a very high IRT referral strategy in CF newborn screening programs whose variant panel does not include all CF-causing variants in CFTR2 or does not have a variant panel that achieves at least 95% sensitivity in all ancestral groups within the state; (3) The CF Foundation recommends that CF newborn screening algorithms should not limit <i>CFTR</i> variant detection to the F508del variant or variants included in the American College of Medical Genetics-23 panel; (4) The CF Foundation recommends that CF newborn screening programs screen for all CF-causing <i>CFTR</i> variants in CFTR2; (5) The CF Foundation recommends conducting <i>CFTR</i> variant screening twice weekly or more frequently as resources allow; (6) The CF Foundation recommends the inclusion of a <i>CFTR</i> sequencing tier following IRT and <i>CFTR</i> variant panel testing to improve the specificity and positive predictive value of CF newborn screening; (7) The CF Foundation recommends that both the primary care provider and the CF specialist be notified of abnormal newborn screening results. …”
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