ERBB3-related gene PBX1 is associated with prognosis in patients with HER2-positive breast cancer by Shufen Mo, Haiming Zhong, Weiping Dai, Yuanyuan Li, Bin Qi, Taidong Li, Yongguang Cai

“…Utilizing three distinct machine learning algorithms, we identified three signature genes-PBX1, IGHM, and CXCL13-that exhibited significant diagnostic value within the diagnostic model. …”
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A nicotinamide metabolism-related gene signature for predicting immunotherapy response and prognosis in lung adenocarcinoma patients by Meng Wang, Wei Li, Fang Zhou, Zheng Wang, Xiaoteng Jia, Xingpeng Han

“…Four independent prognostic NMRGs (GJB3, CPA3, DKK1, KRT6A) were screened and used to construct a RiskScore model, which exhibited a strong predictive performance. …”
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Machine learning analysis of FOSL2 and RHoBTB1 as central immunological regulators in knee osteoarthritis synovium by Kun Gao, Zhenyu Huang, Zhouwei Liao, Yanfei Wang, Dayu Chen

“…We employed several machine learning algorithms, including least absolute shrinkage and selection operator and support vector machine–recursive feature elimination, to screen for key genes. …”
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Accuracy and interpretability of smartwatch electrocardiogram for early detection of atrial fibrillation: A systematic review and meta‐analysis by Dr. Muhammad Iqhrammullah, Prof. Asnawi Abdullah, Dr. Hermansyah, Fahmi Ichwansyah, Prof. Dr. Ir. Hafnidar A. Rani, Meulu Alina, Artha M. T. Simanjuntak, Derren D. C. H. Rampengan, dr. Seba Talat Al‐Gunaid, dr. Naufal Gusti, dr. Arditya Damarkusuma, Edza Aria Wikurendra

“…Methods Data derived from indexed literature in the Scopus, Scilit, PubMed, Google Scholar, Web of Science, IEEE, and Cochrane Library databases (as of June 1, 2024) were systematically screened and extracted. The quantitative synthesis was performed using a two‐level mixed‐effects logistic regression model, as well as a proportional analysis with Freeman‐Tukey double transformation on a restricted maximum‐likelihood model. …”
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Is body mass index associated with outcomes of mechanically ventilated adult patients in intensive critical units? A systematic review and meta-analysis. by Yonghua Zhao, Zhiqiang Li, Tao Yang, Meiping Wang, Xiuming Xi

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Identification of three T cell-related genes as diagnostic and prognostic biomarkers for triple-negative breast cancer and exploration of potential mechanisms by Zhi-Chuan He, Zheng-Zheng Song, Zhe Wu, Peng-Fei Lin, Xin-Xing Wang

“…Differentially expressed genes (DEGs) between TNBC and other BRCA subtypes were intersected with T cell-related genes to identify candidate biomarkers. Machine learning algorithms were used to screen for key hub genes, which were then used to construct a logistic regression (LR) model. …”
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Integrated multi-omics analysis and machine learning identify G protein-coupled receptor-related signatures for diagnosis and clinical benefits in soft tissue sarcoma by Duo Wang, Duo Wang, Duo Wang, Jihao Tu, Jihao Tu, Jianfeng Liu, Jianfeng Liu, Yuting Piao, Yuting Piao, Yiming Zhao, Yiming Zhao, Ying Xiong, Ying Xiong, Jianing Wang, Jianing Wang, Xiaotian Zheng, Xiaotian Zheng, Bin Liu, Bin Liu

“…We developed a novel machine learning framework that incorporated 12 machine learning algorithms and their 127 combinations to construct a consensus GPRS to screen biomarkers with diagnostic significance and clinical translation, which was assessed by the internal and external validation datasets. …”
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Nitrogen content estimation of apple trees based on simulated satellite remote sensing data by Meixuan Li, Xicun Zhu, Xicun Zhu, Xinyang Yu, Cheng Li, Dongyun Xu, Ling Wang, Dong Lv, Yuyang Ma

“…Support Vector Machine (SVM) and Backpropagation Neural Network (BPNN) algorithms were used to construct and screen the optimal models for apple tree nitrogen content estimation.ResultsResults showed that visible light, red edge, near-infrared, and yellow edge bands were sensitive bands for estimating apple tree nitrogen content. …”
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Longitudinal Digital Phenotyping of Multiple Sclerosis Severity Using Passively Sensed Behaviors and Ecological Momentary Assessments: Real-World Evaluation by Zongqi Xia, Prerna Chikersal, Shruthi Venkatesh, Elizabeth Walker, Anind K Dey, Mayank Goel

“…Among the best-performing models with the least sensor data requirement, the ML algorithm predicted depressive symptoms with an accuracy of 80.6% (F1-score=0.76), high global MS symptom burden with an accuracy of 77.3% (F1-score=0.78), severe fatigue with an accuracy of 73.8% (F1-score=0.74), and poor sleep quality with an accuracy of 72.0% (F1-score=0.70). …”
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EEG Signal Analysis for Numerical Digit Classification: Methodologies and Challenges by Augoustos Tsamourgelis, Adam Adamopoulos

“…We achieve strong differentiation capabilities between digit and non-digit values in all classification algorithms. However, our study also highlights the profound neurological challenges encountered in distinguishing between the digit values, as our model, inspired by the related bibliography, was unable to differentiate between digit values 0 and 1. …”
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The systemic oxidative stress index predicts clinical outcomes of esophageal squamous cell carcinoma receiving neoadjuvant immunochemotherapy by Jifeng Feng, Jifeng Feng, Liang Wang, Xun Yang, Qixun Chen, Qixun Chen

“…Then, a new staging that included TNM and SOSI based on RPA algorithms was produced. In terms of prognostication, the RPA model performed significantly better than TNM classification.ConclusionSOSI is a simple and useful score based on available SOS-related indices. …”
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Machine learning identification of key genes in cardioembolic stroke and atherosclerosis: their association with pan-cancer and immune cells by Tianxiang Zhang, Chunhui Yuan, Mo Chen, Jinjiang Liu, Wei Shao, Ning Cheng

“…Two machine learning algorithms, Least Absolute Shrinkage and Selection Operator (LASSO) regression and Support Vector Machine Recursive Feature Elimination (SVM-RFE), were used to screen for overlapping FRDEGs in CS and AS. …”
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Analysis and Validation of Autophagy-Related Gene Biomarkers and Immune Cell Infiltration Characteristic in Bronchopulmonary Dysplasia by Integrating Bioinformatics and Machine Lea... by Xiao S, Ding Y, Du C, Lv Y, Yang S, Zheng Q, Wang Z, Zheng Q, Huang M, Xiao Q, Ren Z, Bi G, Yang J

“…Subsequently, the hub genes were identified by Lasso and Cytoscape with three machine-learning algorithms (MCC, Degree and MCODE). In addition, hub genes were validated with ROC, single-cell sequence and IHC in hyperoxia mice. …”
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Elucidating the dynamic tumor microenvironment through deep transcriptomic analysis and therapeutic implication of MRE11 expression patterns in hepatocellular carcinoma by Ruiqiu Chen, Chaohui Xiao, Zizheng Wang, Guineng Zeng, Shaoming Song, Gong Zhang, Lin Zhu, Penghui Yang, Rong Liu

“…Publicly available single-cell RNA sequencing (scRNA-seq) data and spatial transcriptomics were utilized to explore MRE11’s dynamic mechanisms in the tumor microenvironment (TME) of both primary and post-immunotherapy cases. We also screened for differentially expressed genes and constructed a robust HCC prognosis model using 101 machine-learning algorithms. …”
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Unraveling shared diagnostic genes and cellular microenvironmental changes in endometriosis and recurrent implantation failure through multi-omics analysis by Dongxu Qin, Yongquan Zheng, Libo Wang, Zhenyi Lin, Yao Yao, Weidong Fei, Caihong Zheng

“…Differential expression analysis and weighted gene co-expression network analysis (WGCNA) were employed to identify key genes. Machine learning algorithms, including Random Forest (RF) and XGBoost, were utilized to screen for shared diagnostic genes, which were subsequently validated through receiver operating characteristic (ROC) analysis and clinical prediction models. …”
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Identification and verification of biomarkers associated with neutrophils in acute myocardial infarction: integrated analysis of bulk RNA-seq, expression quantitative trait loci, a... by Guoqing Liu, Xiangwen Lv, Jiahui Qin, Xingqing Long, Miaomiao Zhu, Chuwen Fu, Jian Xie, Peichun He

“…Hub genes were screened using the least absolute shrinkage and selection operator (LASSO) and random forest (RF) algorithms. …”
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A Non-Uniformity Correction Method for Uncooled Infrared Polarization Imaging Systems by Cailing Zhao, Zhiguo Fan, Yunxiang Zhang

“…Previous non-uniformity correction (NUC) algorithms usually couple polarization information with FPN correction, resulting in the loss of polarization characteristics. …”
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Improving synergistic drug combination prediction with signature-based gene expression features in oncology by Mozhgan Mozaffarilegha, Sajjad Gharaghani

“…We compared their performance with that of conventional drug signatures and chemical structure-based descriptors.Results:Our results demonstrate that models incorporating DRS features consistently outperform traditional approaches across all evaluated algorithms. …”
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Meta-analyses of IL1A polymorphisms and the risk of several autoimmune diseases published in databases. by Hang Su, Na Rei, Lei Zhang, Jiaxiang Cheng

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Identification of the immune infiltration and biomarkers in ulcerative colitis based on liquid–liquid phase separation-related genes by Zhixing Hong, Shilin Fang, Haihang Nie, Jingkai Zhou, Yuntian Hong, Lan Liu, Qiu Zhao

“…We identified the hub LLPS-RGs (DE-LLPS-RGs) (HSPB3, SLC16A1, TRIM22, SRI, PLEKHG6, GBP1, PADI2) by machine learning algorithms. Hub genes were screened that displayed high prediction accuracy of UC patients. …”
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