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1021
Immune Evasion Mechanism Mediated by ITPRIPL1 and Its Prognostic Implications in Glioma
Published 2025-08-01“…Ninety‐eight machine learning algorithm combinations were screened to identify the optimal predictive model. …”
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1022
Case-control study combined with machine learning techniques to identify key genetic variations in GSK3B that affect susceptibility to diabetic kidney diseases
Published 2025-06-01“…On the other hand, the expression levels and kinase activity of GSK3β in exosomes differed significantly between patients with different genotypes of the GSK3B, suggesting that the effect of GSK3B gene polymorphisms on GSK3β expression and activity may be an important mechanism leading to individual differences in susceptibility to DKD. XG Boost algorithm model identified rs60393216 and rs1488766 as important biomarkers for clinical early warning of DKD.…”
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1023
Identification and validation of endoplasmic reticulum stress-related diagnostic biomarkers for type 1 diabetic cardiomyopathy based on bioinformatics and machine learning
Published 2025-03-01“…The ERDEGs diagnostic model was developed based on a combination of LASSO and Random Forest approaches, and the diagnostic performance was evaluated by the area under the receiver operating characteristic curve (ROC-AUC) and validated against external datasets. …”
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1024
Automated Detection of Reduced Ejection Fraction Using an ECG-Enabled Digital Stethoscope
Published 2025-03-01“…Recently, electrocardiogram-based algorithms have shown promise in detecting ALVSD. Objectives: The authors developed and validated a convolutional neural network (CNN) model using single-lead electrocardiogram and phonocardiogram inputs captured by a digital stethoscope to assess its utility in detecting individuals with actionably low ejection fractions (EF) in a large cohort of patients. …”
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1025
Multi-Target Mechanism of Compound Qingdai Capsule for Treatment of Psoriasis: Multi-Omics Analysis and Experimental Verification
Published 2025-06-01“…CQC ingredients-targets network was constructed using these ingredients and their targets. Screening of CQC anti-psoriasis core targets using machine learning algorithm. …”
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1026
Determining optimal strategies for primary prevention of cardiovascular disease: a synopsis of an evidence synthesis study
Published 2025-08-01“…A machine learning study developed a parallel Convolutional Neural Network algorithm with 96.4% recall and 99.1% precision for study screening. …”
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1027
Unveiling diagnostic biomarkers and therapeutic targets in lung adenocarcinoma using bioinformatics and experimental validation
Published 2025-07-01“…In addition, a machine learning model constructed based on Stepglm[backward] with the random forest algorithm achieved the highest C-index (0.999) and screened eight core genes, among which ST14 was noted for its excellent predictive ability. …”
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1028
Smart driving assistance system for mining operations in foggy environments
Published 2025-03-01“…Finally, the screen fitted in the dashboard is forward-facing to the operator's seat and displays the final output. …”
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1029
Exhaled volatile organic compounds as novel biomarkers for early detection of COPD, asthma, and PRISm: a cross-sectional study
Published 2025-05-01“…Subsequently, classification models were established by machine learning algorithms, based on these VOC markers along with baseline characteristics. …”
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1030
Cell death-related signature genes: risk-predictive biomarkers and potential therapeutic targets in severe sepsis
Published 2025-05-01“…Further combining cell death-related gene screening and four machine learning algorithms (including LASSO-logistic, Gradient Boosting Machine, Random Forest and xGBoost), nine SeALAR-characterized cell death genes (SeDGs) were screened and a risk prediction model based on SeDGs was constructed that demonstrated good prediction performance. …”
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1031
Opening closed doors: using machine learning to explore factors associated with marital sexual violence in a cross-sectional study from India
Published 2021-12-01“…Analyses included iterative thematic analysis (L-1 regularised regression followed by iterative qualitative thematic coding of L-2 regularised regression results) and neural network modelling.Outcome measure Participants reported their experiences of sexual violence perpetrated by their current (or most recent) husband in the previous 12 months. …”
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1032
Improving the accuracy of remotely sensed TSS and turbidity using quality enhanced water reflectance by a statistical resampling technique
Published 2025-08-01“…The statistical resampling approach based on GMM was applied to Sentinel-2 (S2) imagery to produce input to Machine Learning (ML) algorithms to retrieve the TSS and turbidity for target river sections. …”
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1033
Characterization and stratification of risk factors of stroke in people living with HIV: A theory-informed systematic review
Published 2025-05-01“…Predictive and preventative models should target factors with a high causality index and low investigative costs. …”
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1034
A Deep Learning Method for Pneumoconiosis Staging on Chest X-Ray Under Label Noise
Published 2025-01-01“…The ambiguous properties of small opacities in pneumoconiosis chest radiographs can cause diagnostic drift, which in turn leads to the presence of noisy labels in the datasets collected from hospitals that can negatively impact the generalization of deep learning models. To tackle this issue, we propose COFINE, a novel coarse-to-fine noise-tolerant deep learning method for the staging of pneumoconiosis chest radiographs, which comprises two procedures: coarse screening and fine learning. …”
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1035
Mechanical positioning of multiple nuclei in muscle cells.
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1036
Immunotyping of thyroid cancer for clinical outcomes and implications
Published 2025-05-01“…Furthermore, the prognostic model’s utility in predicting immunotherapy response was analyzed. …”
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1037
Diagnostic Value of F-FDG PET/CT Radiomics in Lymphoma: A Systematic Review and Meta-Analysis
Published 2025-05-01“…Six meta-regressions were conducted on study performance, considering sample size, image modality, region of interest (ROI) selection, ROI segmentation, radiomics mode, and algorithms. Results In total, 20 studies classified as type 2a or above according to the Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis (TRIPOD) statement were included for this systematic review and meta-analysis. …”
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1038
Spatial and temporal distribution patterns and factors influencing hepatitis B in China: a geo-epidemiological study
Published 2025-04-01“…Spatial autocorrelation analysis and spatiotemporal scanning were used to analyze the spatiotemporal distribution characteristics. The random forest algorithm was used to screen the potential influencing factors. …”
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1039
Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders
Published 2025-01-01“…In this review, we compare two-dimensional and three-dimensional hiPSC formats for disease modeling, discuss the applications of functional assays, and offer insights on incorporating ML into hiPSC-based NDD research and drug screening.…”
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1040
Identification and verification of XDH genes in ROS induced oxidative stress response of osteoarthritis based on bioinformatics analysis
Published 2025-08-01“…An artificial neural network model was constructed for the hub genes, and immune analysis was conducted using the ssGSEA algorithm. …”
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