Integrated multi-omics analysis and predictive modeling of heart failure using sepsis-related gene signature. by Yiping Lang, Tianyu Liang, Fei Li

“…<h4>Methods</h4>Three sepsis-related datasets (GSE65682, GSE54514, and GSE95233) were analyzed to identify differentially expressed genes (DEGs) following batch effect correction using the ComBat algorithm. With the use of elastic net regularization and the glmnet package in R, Lasso Cox regression was employed to screen out gene signatures. …”
Get full text

Neutrophil- and Endothelial Cell-Derived Extracellular Microvesicles Are Promising Putative Biomarkers for Breast Cancer Diagnosis by Thayse Batista Moreira, Marina Malheiros Araújo Silvestrini, Ana Luiza de Freitas Magalhães Gomes, Kerstin Kapp Rangel, Álvaro Percínio Costa, Matheus Souza Gomes, Laurence Rodrigues do Amaral, Olindo Assis Martins-Filho, Paulo Guilherme de Oliveira Salles, Letícia Conceição Braga, Andréa Teixeira-Carvalho

“…Machine learning approaches were employed to determine the performance of MVs to identify BC and to propose BC classifier algorithms. <b>Results:</b> Patients with BC had more neutrophil- and endothelial cell-derived MVs than controls before treatment. …”
Get full text

A hybrid super learner ensemble for phishing detection on mobile devices by Routhu Srinivasa Rao, Cheemaladinne Kondaiah, Alwyn Roshan Pais, Bumshik Lee

“…Abstract In today’s digital age, the rapid increase in online users and massive network traffic has made ensuring security more challenging. Among the various cyber threats, phishing remains one of the most significant. …”
Get full text

Exploring timely and safe discharge from ICU: a comparative study of machine learning predictions and clinical practices by Chao Ping Wu, Rachel Benish Shirley, Alex Milinovich, Kaiyin Liu, Eduardo Mireles-Cabodevila, Hassan Khouli, Abhijit Duggal, Anirban Bhattacharyya

“…It also highlights ML models can serve as a promising screening tool to enhance ICU discharge, presenting a pathway toward more efficient and reliable critical care decision-making.…”
Get full text

AI-Powered Synthesis of Structured Multimodal Breast Ultrasound Reports Integrating Radiologist Annotations and Deep Learning Analysis by Khadija Azhar, Byoung-Dai Lee, Shi Sub Byon, Kyu Ran Cho, Sung Eun Song

“…Our method synthesizes comprehensive breast US reports by combining the extracted information from radiologists’ annotations during routine screenings with the analysis results from deep learning algorithms on multimodal US images. …”
Get full text

Smart driving assistance system for mining operations in foggy environments by Swades Kumar Chaulya, Monika Choudhary, Naresh Kumar, Vikash Kumar, Abhishek Chowdhury

“…In image processing under dense fog where visibility is below 5 m, typical performance standards are around 0.9 for contrast, above 0.5 for structural similarity index measure, over 20 dB for peak signal-to-noise ratio, over 0.5 for visual information fidelity, and more than 0.5 for universal quality index. Thus, the test results indicate that the proposed image enhancement algorithm produced significantly improved images, proving its effectiveness in extremely low visibility situations. …”
Get full text

Proteomic analysis of blood plasma as a tool for personalized diagnosis of lung adenocarcinoma by D. N. Korobkov, A. S. Kononikhin, S. D. Semenov, H. L. Kordzaya, A. G. Brzhozovskiy, A. E. Bugrova, E. Yu. Vasilieva, D. Yu. Kanner, E. N. Nikolaev, A. A. Komissarov

“…Classifiers developed based on these protein panels make it possible to distinguish between patients with LAC and healthy controls, as well as to detect the presence of metastases among patients with LAC, with sensitivity and specificity of more than 90 %.Conclusion. The data obtained can be used to develop new tests for LAC screening and predicting disease outcomes based on the blood plasma proteome. …”
Get full text

Deaths ascribed to non-communicable diseases among rural Kenyan adults are proportionately increasing: evidence from a health and demographic surveillance system, 2003-2010. by Penelope A Phillips-Howard, Kayla F Laserson, Nyaguara Amek, Caryl M Beynon, Sonia Y Angell, Sammy Khagayi, Peter Byass, Mary J Hamel, Anne M van Eijk, Emily Zielinski-Gutierrez, Laurence Slutsker, Kevin M De Cock, John Vulule, Frank O Odhiambo

“…<h4>Background</h4>Non-communicable diseases (NCDs) result in more deaths globally than other causes. Monitoring systems require strengthening to attribute the NCD burden and deaths in low and middle-income countries (LMICs). …”
Get full text

Problems and perspectives of family doctors training on the undergraduate stage by Yu. M. Kolesnik, V. D. Syvolap, N. S. Mikhaylovskaya, T.O. Kulinich

“…The introduction of family medicine requires more training of highly qualified personnel, which should begin at undergraduate stage, using both traditional forms of learning, innovative technologies based on the experience of other medical institutions of Ukraine and the world.…”
Get full text

Ethical and social issues in prediction of risk of severe mental illness: a scoping review and thematic analysis by Ivars Neiders, Signe Mežinska, Neeltje E. M. van Haren

“…First, there are issues that should deserve more attention than they have received thus far (clinical utility, extensive or mandatory use). …”
Get full text

Amyloid Cardiomyopathy: Review of A Fatal Case Report by O. V. Soldatova, I. Ya. Goryanskaya

“…To date, it has been proven that amyloid cardiomyopathy is an important and often undiagnosed cause of chronic heart failure and cardiac arrhythmias, especially in the elderly. There are more than 15 types of precursor proteins capable of causing systemic amyloidosis, but only 2 of them accumulate in the interstitium of the heart: light chains of clonal immunoglobulin (AL) and tetrameric protein transthyretin (TTR). …”
Get full text

Advancement of artificial intelligence based treatment strategy in type 2 diabetes: A critical update by Aniruddha Sen, Palani Selvam Mohanraj, Vijaya Laxmi, Sumel Ashique, Rajalakshimi Vasudevan, Afaf Aldahish, Anupriya Velu, Arani Das, Iman Ehsan, Anas Islam, Sabina Yasmin, Mohammad Yousuf Ansari

“…These person-centred approaches to T2DM management, which are more effective and personalized than some traditional strategies, only work because of the often-hidden synergies between AI algorithms in areas such as diagnostic criteria, predictive methods, and familiar classification tools for subgroups with relevant aspects/predictors on prognosis or treatment responsiveness.…”
Get full text

Machine learning applications in the analysis of sedentary behavior and associated health risks by Ayat S Hammad, Ayat S Hammad, Ali Tajammul, Ismail Dergaa, Ismail Dergaa, Ismail Dergaa, Maha Al-Asmakh, Maha Al-Asmakh

“…Exclusion criteria involved studies older than 20 years or lacking direct relevance. After screening 33 core articles and identifying 13 more through citation tracking, 46 articles were included in the final review.ResultsThis narrative review describes the characteristics of sedentary behavior, associated health risks, and the applications of ML in this context. …”
Get full text

Integrating bioinformatics and machine learning for comprehensive analysis and validation of diagnostic biomarkers and immune cell infiltration characteristics in pediatric septic... by Peng Lyu, Na Xie, Xu-peng Shao, Shuai Xing, Xiao-yue Wang, Li-yun Duan, Xue Zhao, Jia-min Lu, Rong-fei Liu, Duo Zhang, Wei Lu, Kai-liang Fan

“…Abstract This study aims to predict and diagnose pediatric septic shock through the screening of immune infiltration-related biomarkers. …”
Get full text

Iron Ore Information Extraction Based on CNN-LSTM Composite Deep Learning Model by Haili Chen, Mengxiang Xia, Yaping Zhang, Ruonan Zhao, Bingran Song, Yang Bai

“…The bands are subsequently screened by correlation analysis, successive projections algorithm (SPA), and competitive adaptive reweighted sampling (CARS), down to 50 dimensions using principal component analysis (PCA). …”
Get full text

Transmitted drug resistance in the CFAR network of integrated clinical systems cohort: prevalence and effects on pre-therapy CD4 and viral load. by Art F Y Poon, Jeannette L Aldous, W Christopher Mathews, Mari Kitahata, James S Kahn, Michael S Saag, Benigno Rodríguez, Stephen L Boswell, Simon D W Frost, Richard H Haubrich

“…Human immunodeficiency virus type 1 (HIV-1) genomes often carry one or more mutations associated with drug resistance upon transmission into a therapy-naïve individual. …”
Get full text

Prediction of Insulin Resistance in Nondiabetic Population Using LightGBM and Cohort Validation of Its Clinical Value: Cross-Sectional and Retrospective Cohort Study by Ting Peng, Rujia Miao, Hao Xiong, Yanhui Lin, Duzhen Fan, Jiayi Ren, Jiangang Wang, Yuan Li, Jianwen Chen

“…A total of 5 machine learning algorithms, namely random forest, Light Gradient Boosting Machine (LightGBM), Extreme Gradient Boosting, Gradient Boosting Machine, and CatBoost were used. …”
Get full text

Poor Nutritional Status Increases Risk of Postoperative Adverse Events after Surgical Management of Traumatic Ankle Fracture by Sanket Mehta MD, Nicholas Danford MD

“…Patients with poor nutritional status were older (56 vs. 51 years), more likely to present in shock (7.5% vs. 2.3%) and due to motor vehicle collision mechanism (all P< 0.001). …”
Get full text

Helicobacter pylori eradication treatment for gastric carcinoma prevention in asymptomatic or dyspeptic adults: systematic review and Bayesian meta-analysis of randomised controlle... by Teruhiko Terasawa, Isao Miyashiro, Katsuaki Kato, Takaki Yoshikawa, Reo Takaku, Hiroshi Nishida

“…However, concerns about supporting unfocused screening and eradication programme in healthy, asymptomatic populations have arisen. …”
Get full text

Neutrophil extracellular traps-related genes contribute to sepsis-associated acute kidney injury by Tang Shaoqun, Yu Xi, Wang Wei, Luo Yaru, Lei Shaoqing, Qiu Zhen, Yang Yanlin, Sun Qian, Xia Zhongyuan

“…Differentially expressed genes were screened by “limma” package in R. Least absolute shrinkage and selection operator algorithm was applied to identify the hub genes. …”
Get full text