The Use of Machine Learning for Analyzing Real-World Data in Disease Prediction and Management: Systematic Review by Norah Hamad Alhumaidi, Doni Dermawan, Hanin Farhana Kamaruzaman, Nasser Alotaiq

“…The search focused on extracting data regarding the ML algorithms applied; disease categories studied; types of study designs (eg, clinical trials and cohort studies); and the sources of RWE, including EHRs, patient registries, and wearable devices. …”
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Benchmarking Federated Few-Shot Learning for Video-Based Action Recognition by Nguyen Anh Tu, Nartay Aikyn, Nursultan Makhanov, Assanali Abu, Kok-Seng Wong, Min-Ho Lee

“…Additionally, we explore three meta-learning paradigms and three FL algorithms to investigate their effectiveness and suggest the optimal choices for performance improvement. …”
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A Comparison of Recent Global Time-Series Land Cover Products by Peilin Li, Yan Wang, Chisheng Wang, Lin Tian, Meijiao Lin, Siyao Xu, Chuanhua Zhu

“…High-resolution products (e.g., GLC_FCS30D, Dynamic World) are optimal for monitoring fragmented landscapes and urban expansion, whereas long-term datasets (e.g., ESA CCI, MCD12Q1) suit climate trend analysis in stable ecosystems. …”
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Predictive model for sarcopenia in chronic kidney disease: a nomogram and machine learning approach using CHARLS data by Renjie Lu, Shiyun Wang, Pinghua Chen, Fangfang Li, Fangfang Li, Pan Li, Qian Chen, Xuefei Li, Fangyu Li, Suxia Guo, Jinlin Zhang, Jinlin Zhang, Dan Liu, Zhijun Hu

“…Four machine learning algorithms were utilized, with the optimal model undergoing hyperparameter optimization to evaluate the significance of predictive factors.ResultsA total of 1,092 CKD patients were included, with 231 (21.2%) diagnosed with sarcopenia. …”
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‘Machine Learning’ multiclassification for stage diagnosis of Alzheimer’s disease utilizing augmented blood gene expression and feature fusion by Manash Sarma, Subarna Chatterjee

“…Our research identified a subset of 95 gene transcripts exhibiting optimal efficacy from an extensive collection of over 49,000 transcripts within the ADNI gene expression dataset. …”
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Advances and challenges in immunotherapy in head and neck cancer by Hazem Aboaid, Taimur Khalid, Abbas Hussain, Yin Mon Myat, Rishi Kumar Nanda, Ramaditya Srinivasmurthy, Kevin Nguyen, Daniel Thomas Jones, Jo–Lawrence Bigcas, Kyaw Zin Thein

“…Despite advancements, challenges persist, including heterogeneous response rates, immune-related toxicities, and optimal integration of immunotherapy in multimodal treatment regimens. …”
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Evaluating Maize Residue Cover Using Machine Learning and Remote Sensing in the Meadow Soil Region of Northeast China by Zhengwei Liang, Jia Du, Weilin Yu, Kaizeng Zhuo, Kewen Shao, Weijian Zhang, Cangming Zhang, Jie Qin, Yu Han, Bingrun Sui, Kaishan Song

“…The Google Earth Engine (GEE) and remote sensing images from 2019 to 2023 were used to obtain spectral characteristics before the maize seedling stage in Northeast China, followed by constructing the CRC estimation models using machine learning algorithms. To avoid the impact of multicollinearity among data, three machine learning algorithms—ridge regression (RR), partial least squares regression (PLSR), and least absolute shrinkage and selection operator (LASSO)—were employed. …”
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Multi-omics characterization of diabetic nephropathy in the db/db mouse model of type 2 diabetes by Liping Wang, Ran Zhou, Guanghui Li, Xiaodan Zhang, Yan Li, Yinchen Shen, Junwei Fang

“…Background: Despite optimized blood pressure control and glycemic management reducing the incidence of diabetic nephropathy (DN), significant residual risk remains, suggesting the contribution of pathogenic factors independent of glucose metabolism and hemodynamic disturbances. …”
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Electrophysiological changes in the acute phase after deep brain stimulation surgery by Lucia K. Feldmann, Diogo Coutinho Soriano, Jeroen Habets, Valentina D'Onofrio, Jonathan Kaplan, Varvara Mathiopoulou, Katharina Faust, Gerd-Helge Schneider, Doreen Gruber, Georg Ebersbach, Hayriye Cagnan, Andrea A. Kühn

“…Background: With the introduction of sensing-enabled deep brain stimulation devices, characterization of long-term biomarker dynamics is of growing importance for treatment optimization. The microlesion effect is a well-known phenomenon of transient clinical improvement in the acute post-operative phase. …”
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Population-based colorectal cancer risk prediction using a SHAP-enhanced LightGBM model by Guinian Du, Hui Lv, Yishan Liang, Jingyue Zhang, Qiaoling Huang, Guiming Xie, Xian Wu, Hao Zeng, Lijuan Wu, Jianbo Ye, Wentan Xie, Xia Li, Yifan Sun

“…BackgroundColorectal cancer (CRC) is a highly frequent cancer worldwide, and early detection and risk stratification playing a critical role in reducing both incidence and mortality. we aimed to develop and validate a machine learning (ML) model using clinical data to improve CRC identification and prognostic evaluation.MethodsWe analyzed multicenter datasets comprising 676 CRC patients and 410 controls from Guigang City People’s Hospital (2020-2024) for model training/internal validation, with 463 patients from Laibin City People’s Hospital for external validation. Seven ML algorithms were systematically compared, with Light Gradient Boosting Machine (LightGBM) ultimately selected as the optimal framework. …”
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Non-Celiac Villous Atrophy—A Problem Still Underestimated by Katarzyna Napiórkowska-Baran, Paweł Treichel, Adam Wawrzeńczyk, Ewa Alska, Robert Zacniewski, Maciej Szota, Justyna Przybyszewska, Amanda Zoń, Zbigniew Bartuzi

“…Various immune pathways are involved, such as autoimmune deregulation and chronic inflammatory responses, while drug-induced and environmental factors further complicate its clinical picture. …”
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Machine learning-based diagnostic and prognostic models for breast cancer: a new frontier on the clinical application of natural killer cell-related gene signatures in precision me... by Yutong Fang, Rongji Zheng, Yefeng Xiao, Qunchen Zhang, Junpeng Liu, Jundong Wu

“…We constructed ML-based diagnostic models using 12 algorithms and evaluated their performance for identifying the optimal ML diagnostic model. …”
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Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech by Julianna Olah, Win Lee Edwin Wong, Atta-ul Raheem Rana Chaudhry, Omar Mena, Sunny X. Tang

“…Linguistic and paralinguistic features were extracted and ensemble learning algorithms (e.g., XGBoost) were used to train models. …”
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Twice against thrice-weekly hemodialysis (TATH): a multicenter nonrandomized trial by Mabel Aoun, Serge Finianos, Chadia Beaini, Ghassan Sleilaty, Rita Ghaleb, Nicole Nourie, Sami Kais, Joseph El Hajal, Rachad Alameddine, Celine Boueri, Balsam El Ghoul, Sandy Zeidan, Hiba Azar, Antoine Dfouni, Jenny Hawi, Zeina Mechref, Valerie Hage, Dania Chelala

“…Abstract Background The optimal frequency of maintenance hemodialysis remains a subject of debate. …”
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Machine Learning and Deep Learning for Diagnosis of Lumbar Spinal Stenosis: Systematic Review and Meta-Analysis by Tianyi Wang, Ruiyuan Chen, Ning Fan, Lei Zang, Shuo Yuan, Peng Du, Qichao Wu, Aobo Wang, Jian Li, Xiaochuan Kong, Wenyi Zhu

“…Studies that evaluated DL or TML algorithms assessment value on diagnosing LSS were included, while those with duplicated or unavailable data were excluded. …”
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A novel biochemical analysis for ApoE4 quantification in plasma and discrimination of homozygous and heterozygous APOE ε4 carriers by Andrés Rodríguez, Olga Calero, Sergio Veiga, Miriam Menacho-Román, Ignacio Arribas, Lluís Cano, Guillermo García-Ribas, Miguel Calero

“…Conclusion The e4Quant assay is a novel alternative for genotyping to determine APOE ε4 carrier status, while also providing quantitative measurements of ApoE4 levels. …”
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Development of a postoperative recurrence prediction model for stage Ⅰ non-small cell lung cancer patients using multimodal data based on machine learning by ZHANG Di, WU Yi, XU Yu

“…A combined model was further constructed by integrating both feature sets, and model performance was compared to identify the optimal predictive model.Results‍　‍This study screened the features from non-contrast CT images and ultimately selected 7 radiomic features for constructing radiomic model. …”
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Explainable machine learning for predicting distant metastases in renal cell carcinoma patients: a population-based retrospective study by Zhao Hou, Zhao Hou, Peipei Wang, Peipei Wang, Dingyang Lv, Dingyang Lv, Huiyu Zhou, Huiyu Zhou, Zhiwei Guo, Zhiwei Guo, Jinshuai Li, Jinshuai Li, Mohan Jia, Mohan Jia, Hongyang Du, Hongyang Du, Weibing Shuang, Weibing Shuang

“…Hyperparameters were optimized using grid search and tenfold cross-validation. …”
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Artificial intelligence-based prediction of second stage duration in labor: a multicenter retrospective cohort analysisResearch in context by Xiaoqing Huang, Xiaodan Di, Suiwen Lin, Minrong Yao, Suijin Zheng, Shuyi Liu, Wayan Lau, Zhixin Ye, Zilian Wang, Bin Liu

“…Since durations beyond 3 h were rare, we developed binary classification models with thresholds at 1 h and 2 h. After the optimal features selected by recursive feature elimination (RFE) method, four ML algorithms were employed to build the models. …”
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An IoT-enabled AI system for real-time crop prediction using soil and weather data in precision agriculture by MD Shaifullah Sharafat, Nilavro Das Kabya, Rahimul Islam Emu, Mehrab Uddin Ahmed, Jakaria Chowdhury Onik, Mohammad Aminul Islam, Riasat Khan

“…Context: Precision agriculture leverages advanced technologies such as the Internet of Things (IoT) and artificial intelligence (AI) to enhance crop productivity by providing data-driven insights. In Bangladesh, optimizing crop recommendations using real-time soil and environmental data is crucial for improving agricultural decision-making. …”
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