Population-based colorectal cancer risk prediction using a SHAP-enhanced LightGBM model by Guinian Du, Hui Lv, Yishan Liang, Jingyue Zhang, Qiaoling Huang, Guiming Xie, Xian Wu, Hao Zeng, Lijuan Wu, Jianbo Ye, Wentan Xie, Xia Li, Yifan Sun

“…BackgroundColorectal cancer (CRC) is a highly frequent cancer worldwide, and early detection and risk stratification playing a critical role in reducing both incidence and mortality. we aimed to develop and validate a machine learning (ML) model using clinical data to improve CRC identification and prognostic evaluation.MethodsWe analyzed multicenter datasets comprising 676 CRC patients and 410 controls from Guigang City People’s Hospital (2020-2024) for model training/internal validation, with 463 patients from Laibin City People’s Hospital for external validation. Seven ML algorithms were systematically compared, with Light Gradient Boosting Machine (LightGBM) ultimately selected as the optimal framework. …”
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Non-Celiac Villous Atrophy—A Problem Still Underestimated by Katarzyna Napiórkowska-Baran, Paweł Treichel, Adam Wawrzeńczyk, Ewa Alska, Robert Zacniewski, Maciej Szota, Justyna Przybyszewska, Amanda Zoń, Zbigniew Bartuzi

“…Various immune pathways are involved, such as autoimmune deregulation and chronic inflammatory responses, while drug-induced and environmental factors further complicate its clinical picture. …”
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Opportunities, Challenges, and Future Directions for Generative Artificial Intelligence in Library Information Literacy Education: A Scoping Review by Fan YUAN, Jia LI

“…This methodological approach enabled a thorough exploration of current practices while identifying critical gaps in existing research. …”
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Machine learning-based diagnostic and prognostic models for breast cancer: a new frontier on the clinical application of natural killer cell-related gene signatures in precision me... by Yutong Fang, Rongji Zheng, Yefeng Xiao, Qunchen Zhang, Junpeng Liu, Jundong Wu

“…We constructed ML-based diagnostic models using 12 algorithms and evaluated their performance for identifying the optimal ML diagnostic model. …”
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Predicting Index Trend Using Hybrid Neural Networks with a Focus on Multi-Scale Temporal Feature Extraction in the Tehran Stock Exchange by Mohammad Osoolian, Ali Nikmaram, Mahdi Karimi

“…Moreover, to further enhance the performance and resilience of the model, sophisticated feature engineering methodologies are implemented to optimize its overall functionality. ResultsThe results of the study reveal that while the hybrid neural network model, integrating CNN and LSTM components, demonstrates promising capabilities in predicting the TSE Composite Index, its accuracy falls short compared to competing models, particularly at weekly and monthly time scales. …”
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Evaluation of Neural, Systemic and Extracerebral Activations During Active Walking Tasks in Older Adults Using fNIRS by Meltem Izzetoglu, Roee Holtzer

“…Such involved designs further allowed the implementation of advanced signal processing algorithms to separate and evaluate neural, systemic and extracerebral signal contributions on the overall measurements. …”
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Detecting schizophrenia, bipolar disorder, psychosis vulnerability and major depressive disorder from 5 minutes of online-collected speech by Julianna Olah, Win Lee Edwin Wong, Atta-ul Raheem Rana Chaudhry, Omar Mena, Sunny X. Tang

“…Linguistic and paralinguistic features were extracted and ensemble learning algorithms (e.g., XGBoost) were used to train models. …”
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Twice against thrice-weekly hemodialysis (TATH): a multicenter nonrandomized trial by Mabel Aoun, Serge Finianos, Chadia Beaini, Ghassan Sleilaty, Rita Ghaleb, Nicole Nourie, Sami Kais, Joseph El Hajal, Rachad Alameddine, Celine Boueri, Balsam El Ghoul, Sandy Zeidan, Hiba Azar, Antoine Dfouni, Jenny Hawi, Zeina Mechref, Valerie Hage, Dania Chelala

“…Abstract Background The optimal frequency of maintenance hemodialysis remains a subject of debate. …”
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Atrial fibrillation and chronic kidney disease: main clinical characteristics of patients in selected subjects of the Russian Federation by M. A. Druzhilov, T. Yu. Kuznetsova, O. Yu. Druzhilova, U. D. Arustamova, D. V. Gavrilov, A. V. Gusev

“…This emphasizes the need to optimize risk stratification, ACT and algorithms for the prevention of athero­thrombotic events, as well as the development of nephro­protective strategies to reduce the rate of progression of renal dys­function in this cohort of patients.…”
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Predictive Modeling of Acute Respiratory Distress Syndrome Using Machine Learning: Systematic Review and Meta-Analysis by Jinxi Yang, Siyao Zeng, Shanpeng Cui, Junbo Zheng, Hongliang Wang

“…Early detection and accurate prediction of ARDS can significantly improve patient outcomes. While machine learning (ML) models are increasingly being used for ARDS prediction, there is a lack of consensus on the most effective model or methodology. …”
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A novel biochemical analysis for ApoE4 quantification in plasma and discrimination of homozygous and heterozygous APOE ε4 carriers by Andrés Rodríguez, Olga Calero, Sergio Veiga, Miriam Menacho-Román, Ignacio Arribas, Lluís Cano, Guillermo García-Ribas, Miguel Calero

“…Conclusion The e4Quant assay is a novel alternative for genotyping to determine APOE ε4 carrier status, while also providing quantitative measurements of ApoE4 levels. …”
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Development of a postoperative recurrence prediction model for stage Ⅰ non-small cell lung cancer patients using multimodal data based on machine learning by ZHANG Di, WU Yi, XU Yu

“…Radiomic models were established based on extracted features from tumor-dominant regions of interest (ROI) on CT images, while clinical models were developed using demographic characteristics and preoperative laboratory examinations. …”
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Explainable machine learning for predicting distant metastases in renal cell carcinoma patients: a population-based retrospective study by Zhao Hou, Zhao Hou, Peipei Wang, Peipei Wang, Dingyang Lv, Dingyang Lv, Huiyu Zhou, Huiyu Zhou, Zhiwei Guo, Zhiwei Guo, Jinshuai Li, Jinshuai Li, Mohan Jia, Mohan Jia, Hongyang Du, Hongyang Du, Weibing Shuang, Weibing Shuang

“…Hyperparameters were optimized using grid search and tenfold cross-validation. …”
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Developing a Machine Learning Model for Predicting 30-Day Major Adverse Cardiac and Cerebrovascular Events in Patients Undergoing Noncardiac Surgery: Retrospective Study by Ju-Seung Kwun, Houng-Beom Ahn, Si-Hyuck Kang, Sooyoung Yoo, Seok Kim, Wongeun Song, Junho Hyun, Ji Seon Oh, Gakyoung Baek, Jung-Won Suh

“…Among 46,225 patients of the Seoul National University Bundang Hospital, MACCE occurred in 4.9% (2256/46,225), including myocardial infarction (907/46,225, 2%) and stroke (799/46,225, 1.7%), while in-hospital mortality was 0.9% (419/46,225). …”
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Artificial intelligence-based prediction of second stage duration in labor: a multicenter retrospective cohort analysisResearch in context by Xiaoqing Huang, Xiaodan Di, Suiwen Lin, Minrong Yao, Suijin Zheng, Shuyi Liu, Wayan Lau, Zhixin Ye, Zilian Wang, Bin Liu

“…Since durations beyond 3 h were rare, we developed binary classification models with thresholds at 1 h and 2 h. After the optimal features selected by recursive feature elimination (RFE) method, four ML algorithms were employed to build the models. …”
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An IoT-enabled AI system for real-time crop prediction using soil and weather data in precision agriculture by MD Shaifullah Sharafat, Nilavro Das Kabya, Rahimul Islam Emu, Mehrab Uddin Ahmed, Jakaria Chowdhury Onik, Mohammad Aminul Islam, Riasat Khan

“…Several machine learning algorithms, including Random Forest, Gradient Boosting, and Stacking ensembles, as well as deep learning models such as TabNet, were evaluated for crop prediction. …”
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Cellular hierarchy framework based on single-cell and bulk RNA sequencing reveals fatty acid metabolic biomarker MYDGF as a therapeutic target for ccRCC by Ning Wang, Ziyu Xu, Lina Zhang, Lina Zhang, Yanfang Lu, Yanfang Lu, Yanliang Wang, Yanliang Wang, Lei Yan, Lei Yan, Huixia Cao, Huixia Cao, Limeng Wang, Limeng Wang, Fengmin Shao, Fengmin Shao

“…Functional enrichment algorithms, including AUCell, UCell, singscore, ssGSEA, and AddModuleScore, along with hdWGCNA analysis, were used to identify hub genes influencing high FAM of ccRCC. …”
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Comparison of Random Survival Forest Based‐Overall Survival With Deep Learning and Cox Proportional Hazard Models in HER‐2‐Positive HR‐Negative Breast Cancer by Wenqi Cai, Yan Qi, Linhui Zheng, Huachao Wu, Chunqian Yang, Runze Zhang, Chaoyan Wu, Haijun Yu

“…Predictive models were developed using five feature sets and three algorithms (Cox PH, RSF, DeepSurv), with feature selection optimized via Concordance index (C‐index). …”
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Burden of chronic spontaneous urticaria in Italy through healthcare resource utilization and direct costs: a retrospective analysis of real-world using administrative healthcare da... by Giulia Ronconi, Letizia Dondi, Silvia Calabria, Leonardo Dondi, Irene Dell’Anno, Lucia Casoli, Diletta Valsecchi, Ornella Bonavita, Eustachio Nettis, Nello Martini, Carlo Piccinni

“…Conclusions During the first year following the new CSU diagnosis, a lower than recommended antihistamines dispensation while an elevated use of OCS and a low and delayed omalizumab initiation after CSU exacerbation were observed, suggesting the urgent need to optimize treatment management to limit the burden on patients and healthcare systems.…”
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Identification and validation of diagnostic biomarkers and immune cell abundance characteristics in Staphylococcus aureus bloodstream infection by integrative bioinformatics analys... by Junhong Shi, Li Shen, Yanghua Xiao, Cailing Wan, Bingjie Wang, Peiyao Zhou, Jiao Zhang, Weihua Han, Rongrong Hu, Fangyou Yu, Hongxiu Wang

“…Gene expression dataset GSE33341 was optimized as the discovery dataset, which contained samples from human and mice. …”
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