LncRNAs in oncogenic microenvironment: from threat to therapy by Dipanjan Roy, Bireswar Bhattacharya, Rudra Chakravarti, Prabhjot Singh, Mansi Arya, Anirban Kundu, Ajay Patil, Bhukiya Siva, Sunny Mehta, Tawsif Ahmed Kazi, Dipanjan Ghosh

“…Furthermore, lncRNAs also demonstrated an association with cancer growth and progression by regulating key pathways governing cell growth, epithelial-mesenchymal transition and metastasis. This makes lncRNAs an attractive target for the treatment of cancer and can also be used as a marker for the diagnosis and prognosis of diseases due to their differential expression in diseased samples. …”
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Leveraging free-text diagnoses to identify patients with diabetes mellitus, obesity or dyslipidaemia – a cross-sectional study in a large Swiss primary care database by Donika Balaj, Jakob M. Burgstaller, Audrey Wallnöfer, Katja Weiss, Oliver Senn, Thomas Rosemann, Thomas Grischott, Stefan Markun, and the FIRE research group

“…Diagnoses documented in a free-text entry field for diagnoses were manually coded for target diseases. Cases were defined as patients with a corresponding coded free-text diagnosis or meeting predefined criteria in structured EMR components (medication data or clinical and laboratory parameters). …”
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Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. by Jonathan A Eisen, Robert S Coyne, Martin Wu, Dongying Wu, Mathangi Thiagarajan, Jennifer R Wortman, Jonathan H Badger, Qinghu Ren, Paolo Amedeo, Kristie M Jones, Luke J Tallon, Arthur L Delcher, Steven L Salzberg, Joana C Silva, Brian J Haas, William H Majoros, Maryam Farzad, Jane M Carlton, Roger K Smith, Jyoti Garg, Ronald E Pearlman, Kathleen M Karrer, Lei Sun, Gerard Manning, Nels C Elde, Aaron P Turkewitz, David J Asai, David E Wilkes, Yufeng Wang, Hong Cai, Kathleen Collins, B Andrew Stewart, Suzanne R Lee, Katarzyna Wilamowska, Zasha Weinberg, Walter L Ruzzo, Dorota Wloga, Jacek Gaertig, Joseph Frankel, Che-Chia Tsao, Martin A Gorovsky, Patrick J Keeling, Ross F Waller, Nicola J Patron, J Michael Cherry, Nicholas A Stover, Cynthia J Krieger, Christina del Toro, Hilary F Ryder, Sondra C Williamson, Rebecca A Barbeau, Eileen P Hamilton, Eduardo Orias

“…Overall, the gene set is robust, with more than 27,000 predicted protein-coding genes, 15,000 of which have strong matches to genes in other organisms. …”
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Understanding the Phenomenon of Smuggling from the Perspective of Activists Known as “Shoti” by Ali Feizolahi, Zahra Rezaeinasab, Shabnam Yari

“…This analysis involved coding that led to the identification of 226 concepts, 43 sub-categories, and 15 main categories. …”
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Mortality risk prediction of high-sensitivity C-reactive protein in suspected acute coronary syndrome: A cohort study. by Amit Kaura, Adam Hartley, Vasileios Panoulas, Ben Glampson, Anoop S V Shah, Jim Davies, Abdulrahim Mulla, Kerrie Woods, Joe Omigie, Anoop D Shah, Mark R Thursz, Paul Elliott, Harry Hemmingway, Bryan Williams, Folkert W Asselbergs, Michael O'Sullivan, Graham M Lord, Adam Trickey, Jonathan Ac Sterne, Dorian O Haskard, Narbeh Melikian, Darrel P Francis, Wolfgang Koenig, Ajay M Shah, Rajesh Kharbanda, Divaka Perera, Riyaz S Patel, Keith M Channon, Jamil Mayet, Ramzi Khamis

“…This relationship was independent of troponin in all suspected ACS patients and was further verified in those who were confirmed to have an ACS diagnosis by clinical coding. The main limitation of our study is that we did not have data on underlying cause of death; however, the exclusion of those with abnormal WCC or hsCRP levels >15 mg/L makes it unlikely that sepsis was a major contributor.…”
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Perturbations of microRNA function in mouse dicer mutants produce retinal defects and lead to aberrant axon pathfinding at the optic chiasm. by Rita Pinter, Robert Hindges

“…<h4>Background</h4>During development axons encounter a variety of choice points where they have to make appropriate pathfinding decisions. The optic chiasm is a major decision point for retinal ganglion cell (RGC) axons en route to their target in order to ensure the correct wiring of the visual system. …”
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Assembly and Analysis of the Mitochondrial Genome of <i>Hippophae rhamnoides</i> subsp. <i>sinensis</i>, an Important Ecological and Economic Forest Tree Species in China by Jie Li, Song-Song Lu, Yang Bi, Yu-Mei Jiang, Li-Dan Feng, Jing He

“…<i>sinensis</i> and offer theoretical support for understanding the evolutionary mechanisms within the <i>Hippophae</i> genus and the selection of molecular breeding targets.…”
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Evaluation of the Physical Education Literacy Plan in Elementary Schools: A Qualitative Research by Maryam Kian, Saeideh Dehghani

“…The data were analyzed by "coding" and "categorization". The validity of the data was confirmed through the "triangulation” in the form of "data" and "researcher" types. …”
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LncRNAs regulates cell death in osteosarcoma by Ping’an Zou, Zhiwei Tao, Zhengxu Yang, Tao Xiong, Zhi Deng, Qincan Chen, Li Niu

“…Abstract Despite improvements, prognosis in osteosarcoma patients remains poor, making it essential to identify additional and more robust therapeutic targets. …”
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Antcin-H, a natural triterpene derived from Antrodia cinnamomea, ameliorates dextran sulfate sodium-induced colitis in mice by inhibiting the NLRP3 inflammasome by Wei-Ting Wong, Lan-Hui Li, Hsiao-Wen Chiu, Mridula P. Menon, Hsien-Ta Hsu, Wen-Yu Lin, Chun-Hsien Wu, Chen-Lung Ho, Kuo-Feng Hua

“…Abnormal activation of the NLRP3 inflammasome is a crucial factor in the pathogenesis of IBD, making it an attractive therapeutic target. We discovered that Antcin-H, a triterpene isolated from the unique medicinal fungus Antrodia cinnamomea found in Taiwan, effectively inhibits the NLRP3 inflammasome in macrophages and alleviates dextran sulfate sodium (DSS)-induced colitis in a mouse model. …”
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Reasons for not Referral to health centers in Zahedan: a case study of 2022 by Mehdi Zanganeh Baygi, Mohammad Hassan Amiri Moghaddam, Mahdi Koolaji, Mostafa Peyvand, Sayedeh Narges Noormohamadi

“…Finally, coding was done using the conventional content analysis method. …”
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Insight Into the Nuclear and Mitochondrial Genome of the Caribbean King Crab Maguimithrax spinosissimus (Crustacea: Brachyura: Mithracidae) to Support Fisheries Management and Cons... by Juan Antonio Baeza

“…Also, its abbreviated larval period makes it a candidate for mariculture to support coral reef restoration efforts. …”
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Circular RNAs in Cervical Cancer: What are the Prospects? by S. A. Begliarzade, R. I. Tamrazov

“…Recent advances in non-coding RNAs have opened up new avenues for research, including circular RNAs (circRNAs) as molecules that play a multifaceted role in cellular processes. …”
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Mitochondrial Pathway Signature (MitoPS) predicts immunotherapy response and reveals NDUFB10 as a key immune regulator in lung adenocarcinoma by Peng Luo, Zhenfa Zhang, Lianmin Zhang, Pengpeng Zhang, Mengzhe Zhang, Jianlan Liu, Zhaokai Zhou

“…Functional experiments confirmed that NDUFB10 knockdown significantly enhanced ICIs therapy and increased GZMB+CD8+T cell infiltration, indicating NDUFB10’s crucial role in regulating tumor immune microenvironment and immunotherapy response.Conclusion The MitoPS scoring system reliably predicts prognosis and immunotherapy response in patients with LUAD, providing a novel reference for clinical decision-making. Furthermore, its core gene NDUFB10 regulates tumor immune microenvironment, offering a potential therapeutic target for improving immunotherapy outcomes.…”
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Maternal health care services utilization and associated factors among pregnant women in Kersa district, Jimma zone, Southwest Ethiopia. by Tsedach Alemu Abebe, Gurmesa Tura Debelew

“…<h4>Conclusion</h4>Maternal healthcare service utilization among pregnant women in the study area was lower than national targets and international recommendations. Therefore, increasing women's awareness of maternal healthcare services, addressing physical access to institutional delivery services, strengthening access to transportation such as making ambulance services more accessible, improving road conditions, and increasing household income would likely increase service utilization.…”
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GhLPF1 Associated Network Is Involved with Cotton Lint Percentage Regulation Revealed by the Integrative Analysis of Spatial Transcriptome by Hongyu Wu, Luyao Wang, Shengjun Zhao, Mengtao Gao, Junfeng Cao, Yupeng Hao, Li Yu, Ting Zhao, Siyuan Wang, Jin Han, Yumeng Zhu, Yongyan Zhao, Jie Li, Ke Nie, Kening Lu, Linyun Ding, Zhiyuan Zhang, Tianzhen Zhang, Xueying Guan

“…Here, we identify an R2R3 MYB transcription factor coding gene GhLPF1 within the QTL‐LP‐ChrA06 locus for lint percentage (LP, percentage of lint to seed cotton) through constructing the 1‐Day Post Anthesis Cotton Ovule Spatial Transcriptome Atlas. …”
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Genome-wide profiling of circulating microRNAs in adolescent idiopathic scoliosis and their relation to spinal deformity severity, and disease pathophysiology by Nasrin Khatami, Iurie Caraus, Mahamuda Rahaman, Evguenia Nepotchatykh, Mohamed Elbakry, Wesam Elremaly, Anita Franco, Marie Beauséjour, Anne-Marie Laberge, Stefan Parent, Hubert Labelle, Carl-Éric Aubin, Jean Lachaine, Alain Moreau

“…In addition, investigation of genes targeted by these miRNAs could fill our gaps in our understanding of AIS pathogenesis and reveal new actionable targets.…”
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Anti-radar based on metasurface by Zongzheng Sun, Lei Zhang, Xiao Qing Chen, Hong Xu, Guoyao Xiao, Yi Ning Zheng, Yaojun Wu, Zhixing Liu, Haosheng Fu, Xiaoyang Zhou, Zhanye Chen, Hui Chen, Yinghui Quan, Tie Jun Cui

“…Multi-static nature of MSR also makes it difficult to counter. Here, we propose an anti-radar methodology based on space-time-coding metasurface (STCM) to counter MSR. …”
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PMD-Transformer: A Domain Generalization Approach for Person Re-Identification by Xingguo Jiang, Ling Yu, Guojun Lin, Yuchao Zhang

“…However, the supervised learning strategy on the source domain makes the Transformer-based ReID model inevitably overfit the bias in some regions. …”
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Designing a model for the development of questioning skills based on the school context in primary school students by motahare Khosravi Rad, Ahmad Akbari, Mohammad karimi, Moslem Cherabin

“…In the qualitative section, after conducting interviews and coding processes; as many as 217 open codes, including 11 codes for actors, 37 codes for causal conditions, 12 codes for phenomena, 33 codes for context, 45 codes for intervening conditions, 49 codes for strategy, and 30 codes for Consequences were identified in the initial coding, which decreased after being converted into sub-categories and main categories. …”
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