Integrating machine learning models with multi-omics analysis to decipher the prognostic significance of mitotic catastrophe heterogeneity in bladder cancer by Haojie Dai, Zijie Yu, You Zhao, Ke Jiang, Zhenyu Hang, Xin Huang, Hongxiang Ma, Li Wang, Zihao Li, Ming Wu, Jun Fan, Weiping Luo, Chao Qin, Weiwen Zhou, Jun Nie

“…Conclusion The model we developed was a powerful predictive tool for BLCA prognosis and revealed the impact of mitotic catastrophe heterogeneity on BLCA in multiple dimensions, which then guided clinical decision-making. Furthermore, we highlighted the potential of ANLN as a BLCA target.…”
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Glutathiones’ life in multi-cancers: especially their potential micropetides in liver hepatocellular carcinoma by Didi Ma, Zhenguo Wu, Mengying Zhang, Jian Mao, Wenqin Xu, Lan Jiang, Zuzhen Wang

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Controlled Osteogenic Differentiation of Mouse Mesenchymal Stem Cells by Tetracycline-Controlled Transcriptional Activation of Amelogenin. by Fangfang Wang, Hiroko Okawa, Yuya Kamano, Kunimichi Niibe, Hiroki Kayashima, Thanaphum Osathanon, Prasit Pavasant, Makio Saeki, Hirofumi Yatani, Hiroshi Egusa

“…Regenerative dental therapies for bone tissues rely on efficient targeting of endogenous and transplanted mesenchymal stem cells (MSCs) to guide bone formation. …”
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Transcriptome sequencing reveals the expression profiles of lncRNAs and mRNAs in goat skin tissues with different types of wool coats by Peng Zhao, Hongyu Guo, Jieru Han, Zhiwu Wang, Yanrong Xue, Li Zhang

“…Abstract The diverse coat types of cashmere goats significantly influence cashmere yield, yet the regulatory mechanisms mediated by non-coding RNAs (ncRNAs) remain poorly characterized. …”
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The impact of gut microbial short-chain fatty acids on colorectal cancer development and prevention by Boobalan Thulasinathan, Kanve N. Suvilesh, Sumanas Maram, Erik Grossmann, Yezaz Ghouri, Emma Pernas Teixeiro, Joshua Chan, Jussuf T. Kaifi, Satyanarayana Rachagani

“…This review highlights the critical relationship between gut microbiota and CRC, emphasizing the potential of targeting SCFAs to enhance gut health and reduce CRC risk.…”
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Upregulation of miR-21 in cisplatin resistant ovarian cancer via JNK-1/c-Jun pathway. by Ileabett M Echevarría-Vargas, Fatma Valiyeva, Pablo E Vivas-Mejía

“…Finally, targeting miR-21 reduced cell growth, proliferation and invasion of cisplatin resistant ovarian cancer cells. …”
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Oncogenic viruses rewire the epigenome in human cancer by Jhommara Bautista, Jhommara Bautista, Jhommara Bautista, Andrés Lopez-Cortes

“…These integrated approaches hold transformative potential for more durable and targeted treatment outcomes.…”
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Expression Profiling of a Heterogeneous Population of ncRNAs Employing a Mixed DNA/LNA Microarray by Konstantinia Skreka, Marek Zywicki, Michael Karbiener, Alexander Hüttenhofer, Marcel Scheideler, Mathieu Rederstorff

“…Mammalian transcriptomes mainly consist of non protein coding RNAs. These ncRNAs play various roles in all cells and are involved in multiple regulation pathways. …”
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miRNA mediated mitochondrial function and gene regulation associated with Alzheimer’s disease by Kumudu Subasinghe, Robert Barber, Robert Barber, Robert Barber, Nicole Phillips, Nicole Phillips

“…MicroRNAs (miRNAs) are small non-coding RNA molecules that are known to regulate gene expression in their target locations thereby contributing to epigenetic mechanisms associated with disease pathologies. …”
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The Intersection of Epigenetics and Senolytics in Mechanisms of Aging and Therapeutic Approaches by Daiana Burdusel, Thorsten R. Doeppner, Roxana Surugiu, Dirk M. Hermann, Denissa Greta Olaru, Aurel Popa-Wagner

“…Epigenetics refers to heritable changes in gene expression without altering the DNA sequence, with mechanisms like DNA methylation, histone modification, and non-coding RNA regulation playing critical roles in aging. …”
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MicroRNA 133A Regulates Squalene Epoxidase Expression in Colorectal Cancer Cells to Control Cell Proliferation and Cholesterol Production by Ji-Su Mo, Santosh Lamichhane, Grinsun Sharma, Soo-Cheon Chae

“…MicroRNAs are endogenous and non-coding RNAs that play a pivotal role in the development and progression of various cancers by targeting specific genes. …”
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Genetic Diversity in the <i>Suppressyn</i> Gene Sequence: From Polymorphisms to Loss-of-Function Mutations by Jun Sugimoto, Danny J. Schust, Takeshi Nagamatsu, Yoshihiro Jinno, Yoshiki Kudo

“…It is also anticipated that these findings might direct the development of therapeutic strategies targeting loss-of-function mutations.…”
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Scalable 5G NR Rate-Matcher and Rate-Dematcher for Efficient Use in FPGA Accelerators by Nemanja Filipovic, Dragomir El Mezeni, Vladimir L. Petrovic

“…Therefore, acceleration is often needed to offload heavy processing, focusing on low-density parity-check (LDPC) codec as the most compute-intensive task in the PHY. Additionally, LDPC coding is tightly coupled with rate-matching. This paper presents novel hardware architectures of rate-matcher and rate-dematcher, targeting field programmable gate array (FPGA) RAN accelerators. …”
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How Non-CS preservice teachers conceptualize and engage with computational thinking through 3D game design: Insights from an XR-enhanced maker experience by Tugce Aldemir, Jewoong Moon, Ali Bicer, Gyuri Byun, Carlos Manrique Perez, Vivek Sabanwar

“…While many PSTs remained hesitant about coding, most recognized transferable skills—such as perseverance, creativity, and empathy—as relevant to their future teaching. …”
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MicroRNAs in lung cancer: their role in tumor progression, biomarkers, diagnostic, prognostic, and therapeutic relevance by Madhura Chatterjee, Sayoni Nag, Saurabh Gupta, Tanmoy Mukherjee, Prem Shankar, Deepak Parashar, Arindam Maitra, Kaushik Das

“…Abstract MicroRNAs (miRNAs) are a class of small non-coding RNAs which are associated with post-transcriptional regulation of gene expression. …”
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Epigenetic factors in posttraumatic stress disorder resilience and susceptibility by Tamer A. Addissouky, Ibrahim El Tantawy El Sayed, Yuliang Wang

“…Main body Advanced epigenomic approaches have revealed complex interactions between DNA methylation, histone modifications, and non-coding RNAs in PTSD. Novel findings highlight cell type-specific epigenetic signatures and their temporal dynamics following trauma exposure. …”
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From Isolation to Pilot-Scale Production: <i>Enterococcus faecium</i> YC07 with Urate-Lowering Potential from Fermented Food Jiangshui by Xiaoyu Cao, Qianqian Xu, Yu Zhang, Hai Yan

“…<i>faecium</i> YC07 as a safe and effective probiotic candidate for functional foods targeting hyperuricemia management.…”
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A mixed methods study on non-adherence to oral antidiabetic agents in type 2 diabetes mellitus patients: Unveiling the post-intervention outcomes by Mukesh Kumar, Surendra Reddy Kovvuru, Gurkaran Bedi, Naushad Akhtar, Pritama Paul, Uttam Kumar Paul

“…Data analysis involved qualitative coding and categorization of interview transcripts. …”
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Practitioner perspectives on informing decisions in One Health sectors with predictive models by Kim M. Pepin, Keith Carlisle, Richard B. Chipman, Dana Cole, Dean P. Anderson, Michael G. Baker, Jackie Benschop, Michael Bunce, Rachelle N. Binny, Nigel French, Suzie Greenhalgh, Dion RJ O’Neale, Scott McDougall, Fraser J. Morgan, Petra Muellner, Emil Murphy, Michael J. Plank, Daniel M. Tompkins, David TS Hayman

“…Models can provide assistance to this challenge, but effective development and use of model-based evidence in decision-making (‘model-to-decision workflow’) can be challenging. …”
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Progresses in genetic testing in congenital heart disease by Han Gao, Ying Liu, Wei Sheng, Weinian Shou, Guoying Huang

“…Numerous tools have been developed to interpret variants identified in both coding and non-coding regions through genetic testing, providing substantial reference points for clinical decision-making in CHD management. …”
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