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1741
Higher induction temperatures and the native secretion signal peptide promote rye prolamin 75k γ-secalin production in Komagataella phaffii
Published 2025-08-01“…This, together with their influence on the quality of grain products and their emerging role as biomaterials, makes them an interesting target for further study. …”
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1742
An Efficient Framework for Large Scale Multimedia Content Distribution in P2P Network: I2NC
Published 2015-01-01“…Network coding (NC) makes content distribution more effective and easier in P2P content distribution network and reduces the burden of the original seeder. …”
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1743
The Dual Role of Dietary Phytochemicals in Oxidative Stress: Implications for Oncogenesis, Cancer Chemoprevention, and ncRNA Regulation
Published 2025-05-01“…Recent research has highlighted the regulatory influence of non-coding RNAs (ncRNAs) on cancer initiation and development through the regulation of redox homeostasis and key signaling pathways, which makes them potential targets for anticancer therapy. …”
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1744
Natural Antisense Transcripts in Plants: A Review and Identification in Soybean Infected with Phakopsora pachyrhizi SuperSAGE Library
Published 2013-01-01“…Such a property makes them ideal for interventions in organisms' metabolism. …”
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1745
Clinical Significance of <i>LINC00261</i> in the Pathogenesis of Pancreatic, Colorectal, Hepatocellular, and Gallbladder Cancer
Published 2025-03-01“…In this context, previous studies, including ours, have highlighted the potential of non-coding RNAs, particularly long non-coding RNAs (lncRNAs), in diagnosing and prognosis of various cancers. …”
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1746
One health assessment of farmers’ knowledge, attitudes, and practices (KAPs) on zoonoses in Bangladesh
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1747
Does the decision to disclose non-suicidal self-injury align with decisionmaking frameworks of personal information disclosure? A directed content analysis
Published 2024-09-01“…There is currently no existing framework specific to the process of NSSI disclosure, and the aim of this study was to assess the fit between factors involved in the decision to disclose NSSI and two broader frameworks of disclosure: the Disclosure Decision-Making and Disclosure Processes models. A directed content analysis was used to code interview transcripts from 15 participants, all of whom were university students aged between 18 and 25 (M = 20.33, SD = 1.88), with 11 identifying as female. …”
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1748
Epigenetic regulation in spinal muscular atrophy: emerging areas and future directions
Published 2025-07-01“…These insights have given rise to novel therapeutic strategies, including pharmacological interventions targeting epigenetic pathways and optimized management of environmental factors. …”
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1749
Utrophin up-regulation by an artificial transcription factor in transgenic mice.
Published 2007-08-01“…To our knowledge, this is the first example of a transgenic mouse expressing an artificial gene coding for a zinc finger based transcription factor. …”
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1750
Distinct roles of dentate gyrus and medial entorhinal cortex inputs for phase precession and temporal correlations in the hippocampal CA3 area
Published 2025-01-01“…Our results thus identify a novel and unique functional role of the DG for sequence coding in the CA3 circuit.…”
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1751
Schwann cell reprogramming via EMT-like program following peripheral nerve injury and during nerve regeneration
Published 2025-07-01“…Therapeutic strategies targeting the regulation of the EMT-like program of Schwann cells thus hold significant promise for the treatment of peripheral nerve injury, particularly in cases of severe nerve injury with incomplete recovery and poor functional restoration.…”
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1752
Increased HAGLR expression promotes non–small cell lung cancer proliferation and invasion via enhanced de novo lipogenesis
Published 2017-04-01“…Accumulating evidence indicates that abnormal expression of long non-coding RNAs is associated with tumorigenesis in multiple cancers, including lung cancer. …”
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1753
New views on physiological functions and regulation of butyrylcholinesterase and potential therapeutic interventions
Published 2025-06-01“…These discoveries highlight the potential of miRNA-based therapeutic approaches targeting BChE pathways in various clinical settings.…”
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1754
Immune checkpoints and ncRNAs: pioneering immunotherapy approaches for hematological malignancies
Published 2024-12-01“…Abstract Hematological malignancies are typically treated with chemotherapy and radiotherapy as the first-line conventional therapies. However, non-coding RNAs (ncRNAs) are a rapidly expanding field of study in cancer biology that influences the growth, differentiation, and proliferation of tumors by targeting immunological checkpoints. …”
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1755
Mapping and modeling age-related changes in intrinsic neural timescales
Published 2025-02-01“…However, the impact of these structural changes on temporal coding in the aging brain remains unclear. We mapped intrinsic timescales and gray matter volume (GMV) using magnetic resonance imaging (MRI) in young and elderly adults. …”
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1756
Comprehensive genome annotation of Bombyx mori p50ma strain, a newly developed standard strain
Published 2025-02-01“…Finally, small RNA-seq (sRNA-seq) targeting PIWI-interacting RNA (piRNA) was performed in testes, ovaries, and early embryos to identify piRNA clusters comprehensively. …”
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1757
Contract to kill: GNAS mutation
Published 2025-03-01“…Abstract The mutation in Gsα-coding GNAS exons, popular as gsp oncogene, is the most frequent mutation across all heterotrimeric G proteins involved in oncogenesis. …”
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1758
Advances in the roles and molecular mechanisms of exosomal circular RNAs in regulating the pre-metastatic niche of tumors
Published 2025-04-01“…Circular RNAs (circRNAs), a class of single-stranded closed non-coding RNAs, exhibit high stability, evolutionary conservation, and cell-type specificity. …”
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1759
Life on the Edge: Challenges to Beginning Successful Aging
Published 2025-06-01“…For data analysis, a constant comparative analysis method was employed, progressing through 3 stages: open coding, axial coding, and selective coding.Discussion of Results & ConclusionThe findings indicated that causal conditions, particularly livelihood challenges, along with two facilitating categories—referred to as governmental invisible actions and economic management—played a crucial role in the context of successful aging. …”
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1760
Computational identification of promising genetic markers associated with molecular mechanisms of reduced rice resistance to <i>Rhizoctonia solani</i> under excess nitrogen fertili...
Published 2025-01-01“…Special attention was given to key participants in regulatory pathways under excess nitrogen conditions. Non-coding RNA analysis revealed 30 miRNAs targeting genes of the reconstructed gene network. …”
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