Suggested Topics within your search.
Suggested Topics within your search.
-
1401
IARA: An Underwater Acoustic Database
Published 2025-01-01“…The IARA an Acoustical Recordings Archive (IARA) is available at doi.org/10.5281/zenodo.15777429 and the code used in this paper is available at github.com/labsonar/IARA…”
Get full text
Article -
1402
Nrf1 acts as a highly-conserved determinon for maintaining robust redox homeostasis in the eco-evo-devo process of life histories
Published 2025-07-01“…This is attributable to the facts that Nrf2 has exerted certain ‘double-edged sword’ effects on life process, whereas Nrf1 executes its essential physiobiological functions, along with unique pathophysiological phenotypes, by integrating its ‘three-in-one’ roles elicited as a specific triplet of direct sensor, transducer and effector within multi-hierarchical stress responsive signaling to redox metabolism and target gene reprogramming. Here, we also critically reviewed redox regulation of physio-pathological functions from the eco-evo-devo perspectives, through those coding rules (redox code, stress-coping code, and topogenetic code). …”
Get full text
Article -
1403
Development of patient-centered outcomes for labour and birth: a qualitative study
Published 2022-01-01“…Responses were recorded, transcribed, coded and analyzed using thematic analysis. thematic analysis. …”
Get full text
Article -
1404
Legal Means of Providing the Principle of Transparency of the Artificial Intelligence
Published 2023-06-01“…It is proved that transparency and explainability of the artificial intelligence technology is essential not only for personal data protection, but also in other situations of automated data processing, when, in order to make a decision, the technological data lacking in the input information are taken from open sources, including those not having the status of a personal data storage. …”
Get full text
Article -
1405
-
1406
Gut microbiota orchestrates skeletal muscle development and metabolism in germ-free and SPF pigs
Published 2025-06-01“…RNA-seq analysis revealed that the expression levels of protein-coding genes (PCGs) and LncRNAs in the muscles of GF pigs were generally reduced, with LncRNAs exhibiting more pronounced dynamic changes. …”
Get full text
Article -
1407
Fruit fast tracking and recognition of apple picking robot based on improved YOLOv5
Published 2024-10-01Get full text
Article -
1408
Evaluated empirical systematics of (n, nα) reaction cross-sections at 14 - 15 MeV incident energy
Published 2019-09-01Get full text
Article -
1409
-
1410
Multidimensional insights into exosomes in hepatocellular carcinoma: from genesis to clinical application
Published 2025-08-01“…These nanoscale vesicles play crucial roles in the initiation of precancerous lesions and, by transporting drug resistance-related molecules such as proteins and non-coding RNAs, facilitate the acquisition of resistance to chemotherapy and targeted therapies by tumor cells. …”
Get full text
Article -
1411
The Method of Viral Mimicry in Oncology and Prospects for its Improvement
Published 2023-06-01“…Since retroelements are located in gene introns, viral mimicry can be used in spliceosomal targeted therapy. Transposons serve as drivers of carcinogenesis, therefore, in addition to their artificial activation, oncology uses methods for silencing retroelements using reverse transcriptase inhibitors. …”
Get full text
Article -
1412
Bioinformatic prediction, annotation and experimental validation of conserved microRNAs in Lactuca sativa Linn
Published 2025-08-01“…Abstract MicroRNAs (miRNAs) are non-coding RNAs that play crucial role in post-transcriptional gene regulation, with lengths ranging from 18 to 26 nucleotides (nt). …”
Get full text
Article -
1413
Current advances in the development of microRNA-integrated tissue engineering strategies: a cornerstone of regenerative medicine
Published 2024-10-01“…On this basis, over the past years, a number of research studies have demonstrated that miRNAs can be integrated into tissue-engineered scaffolds to create advanced therapeutic platforms that precisely modulate cellular behavior and offer a controlled and targeted release of miRNAs to optimize tissue repair and regeneration. …”
Get full text
Article -
1414
Functions, mechanisms, and therapeutic implications of noncoding RNA in acute myeloid leukemia
Published 2025-07-01“…Alternative treatments with improved efficacy are required for AML because many patients cannot tolerate the toxic effects of chemotherapy. Non-coding RNAs, including microRNAs (miRNAs), long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs), are attractive treatment targets for cancers and several other diseases. …”
Get full text
Article -
1415
The role of the mTOR pathway in breast cancer stem cells (BCSCs): mechanisms and therapeutic potentials
Published 2025-03-01“…This comprehensive review elucidates the pivotal role of the mechanistic target of rapamycin (mTOR) pathway in regulating BCSCs and its implications for breast cancer progression and treatment resistance. …”
Get full text
Article -
1416
-
1417
miR-210 loss leads to widespread phenotypic and gene expression changes in human 293T cells
Published 2024-12-01“…IntroductionHypoxia responses are critical for myriad physiological and pathological processes, such as development, tissue repair, would healing, and tumorigenesis. microRNAs (miRNAs) are a class of small non-coding RNAs that exert their functions by inhibiting the expression of their target genes, and miR-210 is the miRNA universally and most conspicuously upregulated by hypoxia in mammalian systems. …”
Get full text
Article -
1418
Function of a novel human gene TOX promoting cell proliferation
Published 2013-07-01“…Bioinformatics analysis showed the human gene TOX might locate in cell nuclei. TOX-coding protein was one of high mobility group box family members, which were involved in gene regulation of physiological processes. …”
Get full text
Article -
1419
MSC-derived extracellular vesicles: Precision miRNA delivery for overcoming cancer therapy resistance
Published 2025-06-01“…Carrying a variety of molecules, including microRNAs, small interfering RNAs, long non-coding RNAs, proteins, lipids, and DNA, these vesicles are positioned as promising cancer treatment options. …”
Get full text
Article -
1420