Epigenetic modifications in breast cancer: from immune escape mechanisms to therapeutic target discovery by Ziyu Kang, Junlin Wang, Jiyan Liu, Li Du, Xiaofei Liu

“…Inhibitors targeting epigenetically modified enzymes are effective in treating a wide range of tumors and provide significant patient survival and quality of life. …”
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miRNA-based regulation in growth plate cartilage: mechanisms, targets, and therapeutic potential by Prachi Thakore, Anne M. Delany

“…This review highlights the miRNA-mRNA target networks essential for chondrocyte differentiation. …”
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Identification of nuclear and cytoplasmic mRNA targets for the shuttling protein SF2/ASF. by Jeremy R Sanford, Pedro Coutinho, Jamie A Hackett, Xin Wang, William Ranahan, Javier F Caceres

“…These observations suggest the intriguing hypothesis that SF2/ASF may couple splicing and translation of specific mRNA targets in vivo. Unfortunately the paucity of endogenous mRNA targets for SF2/ASF has hindered testing of this hypothesis. …”
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Cardioepigenetics in action: aerobic exercise-induced modulation of miRNAs, lncRNAs, and chromatin remodeling in cardiovascular disease by Shoudu Yuan, Qi Ye, Ran Qin

“…Emerging evidence highlights the central role of epigenetic modifications and non-coding RNAs including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) in the regulation of gene expression networks underlying cardiovascular homeostasis and disease. …”
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Targeting ferroptosis in prostate cancer management: molecular mechanisms, multidisciplinary strategies and translational perspectives by Hubo Yang, Xuefeng Zhang, Zongming Jia, He Wang, Jixiang Wu, Xuedong Wei, Yuhua Huang, Wenying Yan, Yuxin Lin

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Mechanistic insights into Nrf2-driven pathogenesis and therapeutic targeting in spinal cord injury by Tao Xie, Tao Xie, Jiyu Xu, Xinyu Liu, Yaquan Yu, Yang Lu, Tao Wang, Feng Gao, Hui Yuan, Hui Yuan

“…This review provides an overview of recent research on SCI, examines the physiological roles and mechanisms of Nrf2 in SCI, and explores therapeutic strategies targeting this signaling pathway, including non-coding RNAs, natural and synthetic compounds, and other treatments for SCI.…”
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The roles of LncRNA CARMN in cancers: biomarker potential, therapeutic targeting, and immune response by Huafeng Liu, Xuewen Liu, Yanjun Lu

“…Abstract Long non-coding RNAs (LncRNAs) are crucial regulators of gene expression and cellular processes, with significant implications for cancer research. …”
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Unpacking the behavioural components and delivery features of early childhood obesity prevention interventions in the TOPCHILD Collaboration: a systematic review and intervention c... by Finn Rasmussen, Hein Raat, Cristina Palacios, Barry J Taylor, Lisa Askie, Alison Hayes, Karen Campbell, Wendy Smith, Luke Wolfenden, Sharleen O’Reilly, Eva Corpeleijn, Maria Bryant, Chris Rissel, Denise O’Connor, Paul Chadwick, Jessica Thomson, Anna Lene Seidler, Kylie E Hunter, Ian Paul, Rachael W Taylor, Angie Barba, Kristy Robledo, Ken Ong, Carolina González Acero, Kylie D Hesketh, Rebecca K Golley, Denise A O'Connor, David Espinoza, Sarah Taki, Rachael Taylor, Louise A Baur, Li Ming Wen, Seema Mihrshahi, Emily Oken, Barry Taylor, Ian Marschner, Junilla K Larsen, Kylie Hesketh, Rajalakshmi Lakshman, Amanda L Thompson, Sharleen L O'Reilly, Charles Wood, Alison J Hayes, Kaumudi Joshipura, Lynne Daniels, Alison Karasz, Rebecca Golley, Kaumudi J Joshipura, Nina Cecilie Øverby, Brittany J Johnson, Mason Aberoumand, Sol Libesman, Kristy P Robledo, Charles T Wood, Lukas P Staub, Michelle Sue-See, Ian C Marschner, Jessica L Thomson, Vera Verbestel, Cathleen Odar Stough, Sarah-Jeanne Salvy, Levie T Karssen, Finn E Rasmussen, Mary Jo Messito, Rachel S Gross, Ian M Paul, Ana M Linares, Heather M Wasser, Claudio Maffeis, Ata Ghaderi, Jinan C Banna, Maribel Campos Rivera, Ana B Pérez-Expósito, Jennifer S Savage, Margrethe Røed, Michael Goran, Kayla de la Haye, Stephanie Anzman-Frasca, Kylie Hunter, Brittany Johnson, Louise Baur, Lukas Staub, Shonna Yin, Lee Sanders, Amanda Thompson, Ana Maria Linares, Ana Perez Exposito, Carolina González Acero, Cathleen Odar Stough, Christine Helle, Eliana Perrin, Heather Wasser, Jennifer Savage, Jinan Banna, Junilla Larsen, Kayla dela Haye, Levie Karssen, Maribel Campos Rivera, Nina Øverby, Rachel Gross, Russell Rothman

“…Standard ontologies will be used to code target behaviours, delivery features and BCTs in both published and unpublished intervention materials provided by trialists. …”
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Unraveling the role of hypoxia-inducible factors in cutaneous melanoma: from mechanisms to therapeutic opportunities by Arianna Bellazzo, Barbara Montico, Roberto Guerrieri, Francesca Colizzi, Agostino Steffan, Jerry Polesel, Elisabetta Fratta

“…Finally, we resume available evidence on potential therapeutic approaches aimed at targeting HIF-1α and/or HIF-2α.…”
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Comprehensive in silico analysis to decipher the role of long non-coding RNAs in bread wheat during fusarium head blight and leaf rust interactions by Jyothsna S, Alagu Manickavelu

“…The disclosure of lncRNAs acting as putative miRNA precursors, miRNA targets, and miRNA target mimics highlightsthe interdependence between miRNAs and lncRNAs during fungal invasions in wheat. …”
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Long non-coding RNA AK023617 orchestrates atherosclerosis by regulating the circadian rhythm of immunity-related GTPase family M protein in macrophages by Rongzhe Lu, Hengxuan Cai, Yige Liu, Guanpeng Ma, Jiaxin Wang, Miao Yan, Zhenming Zhang, Bo Yu, Zhaoying Li, Shaohong Fang

“…Acute coronary events show a diurnal rhythm, and atherosclerotic plaque vulnerability, as a histomorphological characteristic of major adverse cardiovascular events, is a key target for intervention. Although oscillating microRNAs reduce plaque stability by facilitating macrophage apoptosis in lesions, whether rhythmic long non-coding RNA (lncRNA) can regulate diurnal oscillations in plaque stability and the potential underlying mechanism remain unclear. …”
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Long non-coding RNAs modulate glutathione metabolism gene expression and tolerance to Pb stress in root tissue of endophyte-infected rice seedling by He-Fei Sun, Xin-Nan Wang, Ya-Nan Li, Lan-Lan Wang, Yue-Ying Li, Lian-Ju Ma, Xue-Mei Li

“…Endophyte can improve plant resistance to Pb stress, and long non-coding RNAs (lncRNAs) have been proved to play a vital role in response to environmental stress. …”
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The New Paradigm of Italian Disability Regulations, from the Reform Law to the Implementing Decrees, via the New Contracts Code: Change starts with Public Administration by Vittorio Pampanin

“… This contribution aims to highlight how the realization of a real change in the approach to the protection and inclusion needs of people with disabilities primarily starts with public administrations, to which the legislator seems to have assigned the task of initiating and supporting the paradigm shift necessary to make the principles expressed by the United Nations Convention on the Rights of Persons with Disabilities effective. …”
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Upregulation of long non-coding RNA SNHG11 promotes apoptosis and its molecular mechanisms in human osteosarcoma U2OS cells by Zhibing Dai, Yachao Sun, Maierdanjiang Maihemuti, JunWei Du, Renbing Jiang

“…Abstract Osteosarcoma (OS) is a malignant bone tumor of mesenchymal origin, which is common in children and adolescents. Long non-coding RNA (lncRNA) SNHG11 plays important regulatory roles in various cancers, particularly in promoting cell migration, invasion, and proliferation. …”
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CircRNA: the potential biomarkers and therapeutic targets in oral squamous cell carcinoma (OSCC) by Jun-Lin Lv, Jun-Lin Lv, Ru Ma, Ru Ma, Yu-Shan Ren, Qing-Yue Liang, He-Meng Zhang, Gui-Cheng Dong, Jie Li

“…Circular RNAs (circRNAs) are a new category of non-coding RNAs implicated in the molecular pathology of cancer, such as oral squamous cell carcinoma (OSCC). …”
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MiR-646 inhibited cell proliferation and migration by targeting P62 in glioma by Fangyu Ye, Heng Zhang, Qianqian Chen, Yanping Gui, Geng Tian, Yuting Ye, Xin Chen, Haijuan Dong, Xiangshan Fan, Jun Chen, RuiYing Yuan, Li Zhao, Juping Yu

“…MiR-646, a small non-coding RNA, poorly expressed in a variety of tumors. …”
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A Systematic Review of the Expression Pattern of Long Non-Coding RNAs SNHG5, SNHG17, and SNHG26 in Human Solid Tumors by Elham Aminifar, Hassan Mehrad-Majd, Yalda Ravanshad, Amirhossein Sahebkar

“…Introduction: Small nucleolar RNA host genes (SNHGs) are a class of long non-coding RNAs that have been increasingly associated with various cancers and are emerging as key players in cancer progression.This systematic review aimed to analyze the expression patterns and potential roles of SNHG5, SNHG17, and SNHG26 in various solid tumors.Methods: A comprehensive literature search was conducted across databases including PubMed, Cochrane, and Google Scholar, to identify relevant studies. …”
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A combination of activation and repression by a colinear Hox code controls forelimb-restricted expression of Tbx5 and reveals Hox protein specificity. by Satoko Nishimoto, Carolina Minguillon, Sophie Wood, Malcolm P O Logan

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Critical Analysis of Living Law Formulation in Law No. 1 of 2023 Concerning the Criminal Code: Towards Law Reform to Realize Justice with the Spirit of Pancasila by Aris Hardinanto, Barda Nawawi Arief, Joko Setiyono, Zico Junius Fernando, Nahdiya Sabrina

“…The culmination of this preparation was the promulgation of the Criminal Code Bill on January 2, 2023, through Law No. 1 of 2023 concerning the Criminal Code (KUHP). …”
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Silencing of long non-coding RNA CCAT2 depressed malignancy of oral squamous cell carcinoma via Wnt/β-catenin pathway by Yuji Ma, Xuanhao Hu, Chao Shang, Ming Zhong, Yan Guo

“…CCAT2 (colon cancer–associated transcript 2) gene is affiliated with long non-coding RNAs, which are often found to have important regulatory roles in cancers. …”
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