Suggested Topics within your search.
Suggested Topics within your search.
-
661
Long non‐coding RNA CASC15 enhances learning and memory in mice by promoting synaptic plasticity in hippocampal neurons
Published 2024-12-01“…Emerging research suggests that long non‐coding RNAs play a role in neural development and function. …”
Get full text
Article -
662
Discovery of candidate functional non-coding mutations in acute myeloid leukemia using single-cell chromatin accessibility sequencing
Published 2025-05-01“…Importantly, we pinpoint candidate functional non-coding mutations that associate with alteration of target gene expression in AML. …”
Get full text
Article -
663
Long non-coding RNA SeT and miR-155 regulate the Tnfα gene allelic expression profile.
Published 2017-01-01“…It is becoming increasingly appreciated that the non-coding genome may have a great impact on the regulation of chromatin structure and gene expression. …”
Get full text
Article -
664
Transcriptomic analysis reveals long non-coding RNA involved in the key metabolic pathway in response to Botrytis cinerea in kiwifruit
Published 2025-04-01“…Abstract Background Understanding the molecular mechanisms that confer kiwifruit resistance to Botrytis cinerea is essential for developing resistant cultivars. Long non-coding RNAs (lncRNAs), known to participate in various physiological processes including plant defense against diseases, have an undefined role in kiwifruit’s resistance. …”
Get full text
Article -
665
An Emphasis on the Role of Long Non-Coding RNAs in Viral Gene Expression, Pathogenesis, and Innate Immunity in Viral Chicken Diseases
Published 2025-05-01“…Understanding these interactions may provide valuable insights into the spatial and temporal regulation of lncRNAs, aid in the identification of potential drug targets, and reveal the expression patterns of lncRNA and coding gene transcripts in response to different viral infections in avian species.…”
Get full text
Article -
666
Channel Estimation and Pilot Design for Uplink Sparse Code Multiple Access System Based on Complex-Valued Sparse Autoencoder
Published 2025-01-01“…Especially, in sparse code multiple access (SCMA) system, the accuracy of channel estimation has a significant impact on decoding performance. …”
Get full text
Article -
667
Long Intergenic Non-Coding RNAs and <i>BRCA1</i> in Breast Cancer Pathogenesis: Neighboring Companions or Nemeses?
Published 2025-01-01“…Recent attention has shifted towards long non-coding RNAs (lncRNAs) as promising diagnostic, prognostic, and therapeutic targets in the multifaceted progression of breast cancer. …”
Get full text
Article -
668
DNA Damage-Induced Ferroptosis: A Boolean Model Regulating p53 and Non-Coding RNAs in Drug Resistance
Published 2025-01-01“…Additionally, p53-induced miR-34c-5p suppresses cancer cell proliferation and drug resistance by modulating Myc, an oncogene further influenced by non-coding RNAs like circular RNA NOTCH1 (CricNOTCH1) and long non-coding RNA MALAT1. …”
Get full text
Article -
669
-
670
-
671
Cloning-Free Targeting of Endogenous Loci to Generate Fluorescent Reporters in Medaka
Published 2025-06-01“…Here, we provide a protocol for targeting endogenous genes to introduce sequences coding for fluorescent reporters in medaka (Oryzias latipes). …”
Get full text
Article -
672
Integrated lncRNA and mRNA analysis reveals the immune modulatory mechanisms of antimicrobial peptide BSN-37 in mouse peritoneal macrophages
Published 2025-06-01“…Abstract Antimicrobial peptides (AMPs) possess vaccine adjuvant activity; however, their specific targets and molecular mechanisms remain incompletely understood, which hinders their clinical application. …”
Get full text
Article -
673
Emerging clinical and research approaches in targeted therapies for high-risk neuroblastoma
Published 2025-03-01“…Key topics include (a) immunotherapies and immunotargets, (b) non-coding RNAs (long non-coding RNA, microRNA, and circular RNA), (c) molecular biomarkers and pathways, and (d) limitations and future directions.…”
Get full text
Article -
674
Translation suppresses exogenous target RNA-mediated microRNA decay
Published 2025-06-01“…Abstract MicroRNAs (miRNAs) interact with the target mRNAs to induce translational repression and mRNA degradation. …”
Get full text
Article -
675
CircRNA-based AntimiR therapy: A novel approach to hypertension treatment
Published 2025-08-01“…The increasing recognition of the types and functions of non-coding RNAs has opened new avenues for their use as novel therapeutic strategies in the treatment of chronic diseases such as hypertension. …”
Get full text
Article -
676
The mechanism underlying metastasis in triple-negative breast cancer: focusing on the interplay between ferroptosis, epithelial-mesenchymal transition, and non-coding RNAs
Published 2025-01-01“…It is urgent to focus on identifying a workable and effective target for the treatment of TNBC. Cancer metastasis is significantly influenced by epithelial-mesenchymal transition (EMT). …”
Get full text
Article -
677
Neural dynamics of visual working memory representation during sensory distraction
Published 2025-06-01“…We find that VWM and feature-matching sensory distractors are encoded in coding spaces that do not fully overlap, but the separation decreases when distractors negatively impact behavioral performance in recalling the target. …”
Get full text
Article -
678
Circular RNAs: novel noncoding players in male infertility
Published 2024-11-01“…Recent studies have shown contribution of a group of non-coding RNAs, namely circular RNAs (circRNAs) to the etiology of some infertility conditions. …”
Get full text
Article -
679
Exosomes containing long non-coding RNA AGAP2-AS1 promote the differentiation of CD4+ T cells through the miR-424-5p/SGK1 axis in psoriasis
Published 2025-05-01“…BackgroundLong non-coding RNAs (lncRNAs) have been implicated in the pathogenesis of autoimmune diseases. …”
Get full text
Article -
680
Targeting Glycolytic Reprogramming in Cholangiocarcinoma: A Novel Approach for Metabolic Therapy
Published 2024-11-01“…In addition, we performed a bioinformatic analysis of the relationship between CCA and glycolysis to identify and investigate potential targets. The purpose of this study is to provide a theoretical basis for the development of CCA targets.Keywords: cholangiocarcinoma, glycolysis, HK2, PKM2, mechanisms…”
Get full text
Article