REGULATORY INTEGRATION IN THE HEALTHCARE SECTOR OF UKRAINE by Mykhailo D. Diachuk

“…Materials and methods. 20 regulatory and legal documents and 16 scientific literary sources on the topic of the research materials were selected. …”
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Live and heat-killed Leuconostoc mesenteroides counteract the gastrointestinal dysfunction in chronic kidney disease mice through intestinal environment modulation. by Fittree Hayeeawaema, Natthawan Sermwittayawong, Chittipong Tipbunjong, Nawiya Huipao, Paradorn Muangnil, Pissared Khuituan

“…This study aimed to evaluate the probiotic potential of lactic acid bacteria derived from natural sources and to investigate the effects of both live and heat-killed Leuconostoc mesenteroides (Ln.m) on renal and gastrointestinal functions in CKD mice. …”
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Sunlight Noise Mitigation in FMCW LiDAR Using FADOF by Longfei Yin, Wei Tang, Ziwei Geng, Haodi Zhan, Lei Chen, Dasheng Qian, Guohua Wu, Bin Luo

“…Additionally, the system achieves a detection range of at least 17 meters under direct sunlight conditions. …”
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An effective fluorescence strategy based on xanthine oxidase catalysis and the carbon dots’ specific response to ·OH for aminophylline pharmacokinetic studies by Chenfang Miao, Menghan Zhang, Ying Zheng, Xiaoyan Lin, Shuangying Yang, Linlin Xu, Sitong Lu, Zhengjun Huang, Jianyong Huang, Yanjie Zheng, Shaohuang Weng

“…However, efficient and sensitive detection methods remain limited. In this study, high quantum yield carbon dots (CA/EDA-CDs) were synthesized via a hydrothermal method using riboflavin as the carbon source, citric acid and ethylenediamine as functionalizing agents and dopants. …”
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Targeting Amyloid Pathology in Early Alzheimer’s: The Promise of Donanemab-Azbt by Nadia Khartabil, Ayda Awaness

“…It specifically targets and reduces amyloid beta plaques, a hallmark of the disease, potentially slowing progression and preserving cognitive function. However, its administration requires careful patient selection, including genetic testing for ApoE ε4 status, to mitigate risks of ARIA. …”
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The transcription factor Ste12 mediates the regulatory role of the Tmk1 MAP kinase in mycoparasitism and vegetative hyphal fusion in the filamentous fungus Trichoderma atroviride. by Sabine Gruber, Susanne Zeilinger

“…Here we analyzed the functions of the T. atroviride Ste12 transcription factor whose orthologue in yeast is targeted by the Fus3 and Kss1 MAP kinases. …”
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Cost-Effective Photoacoustic Imaging Using High-Power Light-Emitting Diodes Driven by an Avalanche Oscillator by Alberto Prud’homme, Frederic Nabki

“…While lasers have traditionally been the light source for PAI, their high cost and complexity drive interest towards alternative sources like light-emitting diodes (LEDs). …”
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Viewing Global Changes in the Heliosheath with IMAP’s Energetic Neutral Atom Imagers by E. J. Zirnstein, J. Heerikhuisen, D. J. McComas, J. Bower, G. Clark, M. A. Dayeh, H. O. Funsten, M. Gkioulidou, D. G. Mitchell, D. B. Reisenfeld, N. A. Schwadron

“…We aim to answer the following: (i) What are the time delays as a function of energy and direction; (ii) at what energies can we observe changes the soonest; and (iii) what might the ENA source distributions affecting the time delays look like? …”
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Granular analysis of pathways to care and durations of untreated psychosis: A marginal delay model. by Walter S Mathis, Maria Ferrara, Shadie Burke, Emily Hyun, Fangyong Li, Bin Zhou, John Cahill, Emily R Kline, Matcheri S Keshavan, Vinod H Srihari

“…Marginal-delay, or the portion of overall delay attributable to a specific node, was computed as the number of days between the start dates of contiguous nodes on the PTC. Sources of delay within the network of care were quantified and patient characteristic (sex, age, race, income, insurance, living, education, employment, and function) influences on such delays were analyzed via bivariate and mixed model testing.…”
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Rehabilitation impact indices and their independent predictors: a systematic review by Amardeep Thind, Gerald Choon-Huat Koh, Robert Petrella, Cynthia Huijun Chen

“…Objectives To (1) identify all available rehabilitation impact indices (RIIs) based on their mathematical formula, (2) assess the evidence for independent predictors of each RII and (3) propose a nomenclature system to harmonise the names of RIIs.Design Systematic review.Data sources PubMed and references in primary articles.Study selection First, we identified all available RII through preliminary literature review. …”
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Heterogeneously integrated light emitting diodes and photodetectors in the metal-insulator-metal waveguide platform by Kwon Kyungmok, Park Junghoon, You Jong-Bum, Yu Kyoungsik

“…Depending on its bias conditions, a metal-semiconductor-metal section can function as either a light emitting diode or a photodetector directly connected to the MIM waveguides. …”
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Role of Polyphosphate as an Inorganic Chaperone to Prevent Protein Aggregation Under Copper Stress in <i>Saccharolobus solfataricus</i> by José Acevedo-López, Gabriela González-Madrid, Claudio A. Navarro, Carlos A. Jerez

“…In <i>Escherichia coli</i>, polyphosphates also function as inorganic molecular chaperones. The present study aims to investigate whether polyphosphate serves a similar chaperone function in archaea, using <i>Saccharolobus solfataricus</i> as a model organism. …”
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3D-MRI brain glioma intelligent segmentation based on improved 3D U-net network. by Tingting Wang, Tong Wu, Defu Yang, Ying Xu, Dongyang Lv, Tong Jiang, Hengjiao Wang, Qi Chen, Shengnan Xu, Ying Yan, Baoguang Lin

“…This method offers significant guidance for medical diagnosis, grading, and treatment strategy selection.<h4>Methods</h4>Glioma case data were sourced from the BraTS2023 public dataset. …”
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A probabilistic approach for building disease phenotypes across electronic health records by David Vidmar, Jessica De Freitas, Will Thompson, John M. Pfeifer, Brandon K. Fornwalt, Noah Zimmerman, Riccardo Miotto, Ruijun Chen

“…In this paper, we develop multiple heuristic “labeling functions’’ (LFs) for 4 diseases across de-identified EHR data and aggregate their votes through a majority vote approach (MV), a popular open-source approach (Snorkel OSS), and our proposed probabilistic approach (LEVI). …”
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Classification analysis of modern bioreactor systems (review). Part 1. Classification of bioreactors by design parameters by A. A. Dosaev, R. R. Safarov, N. V. Menshutina

“…Due to the active use of bioreactors, in order to optimize production processes and reduce operating costs, new highly efficient automated devices with a variety of functions are being developed using modern automation technologies, artificial intelligence and 3-D printing. …”
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Deepmol: an automated machine and deep learning framework for computational chemistry by João Correia, João Capela, Miguel Rocha

“…On 22 benchmark datasets, DeepMol obtained competitive pipelines compared with those requiring time-consuming feature engineering, model design and selection processes. As one of the first AutoML tools specifically developed for the computational chemistry domain, DeepMol stands out with its open-source code, in-depth tutorials, detailed documentation, and examples of real-world applications, all available at https://github.com/BioSystemsUM/DeepMol and https://deepmol.readthedocs.io/en/latest/ . …”
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Comparative Genomic and Transcriptomic Analysis Provides New Insights into the Aflatoxin B₁ Biodegradability by <i>Kocuria rosea</i> from Deep Sea by Jingying Wang, Jun Nan

“…In addition, this study revealed 1421 differentially expressed genes and 752 upregulated genes between the aflatoxin group and the control group through transcriptome analysis and conducted functional annotation and analysis of functional enrichment. …”
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SentemQC - A novel and cost-efficient method for quality assurance and quality control of high-resolution frequency sensor data in fresh waters [version 1; peer review: 1 approved,... by Sofie Gyritia Madsen van't Veen, Joachim Audet, Eti Ester Levi, Brian Kronvang, Søren Erik Larsen, Erik Jeppesen, Esben Astrup Kristensen, Anders Nielsen, Thomas Alexander Davidson, Jane Rosenstand Laugesen, Peter Mejlhede Andersen

“…The SentemQC method is computationally efficient and features a six-step user-friendly setup for anomaly detection. The method marks anomalies in data using five moving windows. …”
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Regenerative Cartilage Treatment for Focal Chondral Defects in the Knee: Focus on Marrow-Stimulating and Cell-Based Scaffold Approaches by Filippo Migliorini, Francesco Simeone, Tommaso Bardazzi, Michael Kurt Memminger, Gennaro Pipino, Raju Vaishya, Nicola Maffulli

“…Given the limited regenerative capacity of hyaline cartilage, biologically based surgical strategies have emerged to promote tissue repair and restore joint function. This narrative review critically examines current treatment approaches that rely on autologous cell sources and scaffold-supported regeneration. …”
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Big data in visual field testing for glaucoma by Alex T. Pham, Annabelle A. Pan, Jithin Yohannan

“…In this study, we review the use of big data for evaluating the reliability of VF tests, gaining insights into real-world clinical practices and outcomes, understanding new disease associations and risk factors, characterizing the patterns of VF loss, defining the structure–function relationship of glaucoma, enhancing early diagnosis or earlier detection of progression, informing clinical decisions, and improving clinical trials. …”
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