Molecular mechanisms of leukemogenesis by D. A. Domninskiy

“…Such targets can be enzymes, proteins with other (non-enzymatic) functions, genomic DNA, mRNA, or, for example, certain lipid components of cell membranes. …”
Get full text

High-Sensitivity Determination of K, Ca, Na, and Mg in Salt Mines Samples by Atomic Emission Spectrometry with a Miniaturized Liquid Cathode Glow Discharge by Jie Yu, Zhichao Zhang, Quanfang Lu, Duixiong Sun, Shuwen Zhu, Xiaomin Zhang, Xing Wang, Wu Yang

Get full text

FXYD2 marks and regulates maturity of β cells via ion channel-mediated signal transduction by Clarissa Tacto, Meghan Tahbaz, Andrew Salib, Shudi Wang, Fritz Cayabyab, Jinhyuk Choi, Kiyoka Kim, Yu Hamba, Harvey Perez, Paul D. Gershon, Robert Damoiseaux, Tae Gyu Oh, Eiji Yoshihara

“…These results suggest that FXYD2 marks and regulates human β cell maturation via channel-sensing signal transduction and that it can be used as a selection marker for functional heterogeneity of stem cell derived human islet organoids.…”
Get full text

INFORMATION TECHNOLOGY FOR THE INTEGRATED ASSESSMENT OF EXPERT COMPETENCY by Olena Lobach, Igor Babych, Elena Persiyanova

“…The following results were obtained: the problem of assessing the quality of experts was considered; based on the authors’ practical experience and analysis of literature sources, the structural diagram of the properties of experts and their assessment was developed; five main groups of existing methods for assessing the quality of experts were analyzed; existing models of an integrated assessment of the competency of experts were reviewed; a two-stage method for the integrated assessment of the competency of experts was developed by integrating the methods of heuristic, test, and statistical assessment; the main groups of users and functional requirements to the information system for assessing the competency of experts were identified; the database and user interface of the information system were developed; the developed information technology of the integrated assessment of the competency of experts was tested on actual data for selecting an expert group to choose the methodology of project management. …”
Get full text

A Rare Encounter: Gastric Ulcer Penetration into the Splenic Hilum Presenting with Upper Gastrointestinal Bleeding and a Massive Splenic Haematoma—Case Report and Literature Review... by Ioana-Irina Rezuș, Vasile-Claudiu Mihai, Diana Elena Floria, Andrei Olteanu, Vlad Ionut Vlasceanu, Radu Petru Soroceanu, Alin Constantin Pinzariu, Brigitta Teutsch, Sergiu Tudose-Timofeiov

Get full text

Biased thalamic innervation onto the distinct subregion where dopamine receptor 1 is dominantly expressed in the caudal striatum by Fuko Kadono, Jingqi Wang, Kenta Kobayashi, Fuyuki Karube, Fumino Fujiyama

“…Retrograde tracer labeling identified potential sources of subcortical glutamatergic projections. …”
Get full text

Electronic Medical Record Inaccuracies: Multicenter Analysis of Challenges with Modified Lung Cancer Screening Criteria by Candice L. Wilshire, Carson C. Fuller, Christopher R. Gilbert, John R. Handy, Kimberly E. Costas, Brian E. Louie, Ralph W. Aye, Alexander S. Farivar, Eric Vallières, Jed A. Gorden

“…The electronic medical record (EMR) is a source of clinical information that could identify high-risk populations for LCS, including a diagnosis of COPD; however, an unsubstantiated COPD diagnosis in the EMR may lead to inappropriate LCS referrals. …”
Get full text

A Systematic Review and Meta-analysis of Scrub Typhus and its Association with Liver Disease by Shalini Balamurugan, Reenaa Mohan, Jenifer Florence Mary, Kulkarni Sweta, Tresa Remya Athipozhi Thomas, Saranya Selvamurthy, Sanjay Pasupathy

“…The studies selected were all scrub typhus patients associated with liver diseases. …”
Get full text

Main trends of the international market of educational services by T. I. Chinaeva

“…The largest world sources of the international students are such countries now as: India, China, Korea. …”
Get full text

Carbon Dioxide Storage Site Location and Transport Assignment Optimization for Sustainable Maritime Transport by Yanmeng Tao, Ying Yang, Yuquan Du, Shuaian Wang

“…We formulate the problem as a mixed-integer programming (MIP) model and demonstrate that the objective function exhibits submodularity, reflecting diminishing returns in facility investment and ship operations. …”
Get full text

Integrating brain proteomes and genetics to identify novel risk genes in chronic widespread musculoskeletal pain by Zhisen Dai, Yanlin Wu, Huaqing Huang, Huizhe Zheng

“…These genes were expressed in pain-related brain regions and showed selective expression in oligodendrocytes, microglia, dopaminergic neurons, and interneurons. …”
Get full text

Sunflower-based butterfly optimization algorithm with enhanced RNN for the harmonics elimination in multilevel inverter by V. Mohan, G. Krithiga, M. Thamil Alagan, V. Sathya

“…In a cascaded MLI, the Selective Harmonic Elimination (SHE) and Pulse Width Modulation (PWM) approach is employed to mitigate lower harmonics by maintaining the needed fundamental voltage. …”
Get full text

Effects of climate change on goat production and mitigatory measures in semiarid savanna ecosystems by Alban Mugoti, Casper Nyamukanza, Anderson Munengwa, Sizo Moyo, Nation Chikumba

“…Emerging practices such as developing heat-tolerant goat breeds and utilizing drought-resistant forage species through selective breeding programmes and ecological restoration initiatives can be enhanced and adopted. …”
Get full text

The Digital Transformation of Tafsir and Its Implications for Islamic Legal Derivation in the Contemporary Era by Ali Sati, Abdul Halim, Abdul Hayy Nasution, Muhammad Ridwan

“…This article explores the impact of selected tools—such as AI-driven tafsir platforms, semantic databases, and multimedia applications—on formulating Islamic legal reasoning in the digital era. …”
Get full text

Effect of Different Synthetic Nitrogen Forms and Levels on Nitrification and Denitrification Key Genes Abundances: Implications for Oligotrophic Forest Soil Management by Muhammad Jamal Ameer, Yushan Liu, Xiaoting Zhao, Siyu Yan, Tongbao Qu

“…Climate change and anthropogenic nitrogen addition alter the soil physicochemical properties and microbial activity in oligotrophic forest soil. Unbalanced and non-selective nitrogen fertilizer application is lost as gas emissions (N₂O, NO) and also contributed to eutrophication through NO₃⁻ leachate. …”
Get full text

Intensive Care for Acute Liver Failure in Pediatric Practice (Review) by G. A. Avakyan, Yu. V. Bykov, A. N. Obedin

“…Anesthesiologists and intensivists face significant challenges in the diagnosis and prevention of ALF.The aim of this review is to analyze the main triggers, etiology, pathogenesis, clinical manifestations and both specific and supportive treatment approaches for ALF in pediatric intensive care units.The Cochrane Library, PubMed, Medscape and Library.ru databases were used to conduct a systematic search and analysis of the scientific literature using the keywords «acute liver failure, children and adolescents, hepatic encephalopathy, cerebral edema, extracorporeal methods, liver transplantation». A total of 81 sources were selected for review. Inclusion criteria were studies that described the pathogenesis, clinical manifestations, diagnosis and treatment of ALF in the pediatric intensive care unit. …”
Get full text

Characterization of multi-targeted insulin-mimetic antidiabetic peptides using in silico approaches. by Anas Bilal, Ghulam Mustafa

“…The aim of the current study was to develop hypoglycemic peptides (HGPs) from plant sources and to investigate their binding interactions with selected diabetic protein receptors using peptide-protein docking, in order to identify potential peptide candidates for the treatment of diabetes mellitus. …”
Get full text

Optimization of Ultrasonic-Enzymatic-Assisted Extraction of Flavonoids from Sea Buckthorn (<i>Hippophae rhamnoides</i> L.) Pomace: Chemical Composition and Biological Activities by Wenyu Suo, Wenzhe Wang, Dajing Li, Haihong Wu, Haiyan Liu, Wuyang Huang, Yanhong Ma

“…Sea buckthorn pomace (SBP) is a rich source of flavonoid compounds with potential healthy properties. …”
Get full text

Simulation of Vertical Movements of Seawater in Stratified Reservoirs by N. V. Kudinov, A. A. Filina, A. V. Nikitina, D. V. Bondarenko, I. F. Razveeva

“…A software module for numerical simulation of hydrophysical processes of water movement with different salinity and density was developed. This is open-source software that provides not only the redefinition of empirical dependences (as algebraic functions), but also the connection of external simulating modules to display dependences algorithmically.Discussion and Conclusion. …”
Get full text

Feasibility and case studies on converting small hydropower stations to pumped storage by Yangqing Dan, Qingyue Chen, Daren Li, Wenhuan Bai, Weiming Zhou, Anyu Yang, Jia Yang

“…Abstract Hydropower, as a controllable energy source, plays a crucial role in supporting essential functions such as peak shaving, frequency regulation, and load reserve within modern power systems, thereby enhancing the overall economic efficiency and safety of these systems. …”
Get full text