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861
Precision medicine in premature ovarian insufficiency: a focus on the precision therapeutic strategies for mesenchymal stem cells
Published 2025-07-01“…Key issues include the selection of appropriate MSCs sources, the optimization of culture conditions, and the determination of optimal transplantation protocols (encompassing dosage, administration route, and timing), all of which pose significant barriers to clinical translation of MSCs. …”
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862
Safety and Probiotic Evaluation of Lactiplantibacillus plantarum CHEN1 and Its Metabolic Analysis of Soymilk Oligosaccharides
Published 2025-05-01“…The genetic characteristics of the strain were analyzed through genome sequencing and functional annotation. Phenotypic experiments, including hemolytic activity assays, detection of harmful metabolites, antibiotic susceptibility testing, tolerance experiments, hydrophobicity, and autoaggregation assays were conducted to evaluate its safety and probiotic potential. …”
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863
Molecular mechanisms of leukemogenesis
Published 2022-11-01“…Such targets can be enzymes, proteins with other (non-enzymatic) functions, genomic DNA, mRNA, or, for example, certain lipid components of cell membranes. …”
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864
Methylenetetrahydrofolate Reductase Gene rs1801133 and rs1801131 Polymorphisms and Essential Hypertension Risk: A Comprehensive Analysis
Published 2022-01-01“…Similar associations were also found in subgroups defined by the source of controls and genotype methods. To our regret, based on the limited studies, no association was detected for rs1801131 polymorphism. …”
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865
The effect of boron mineral on energy metabolism and antioxidant activity in purebred arabian foals
Published 2025-08-01“… Boron mineral is reported to have important functions in lipid and energy metabolism, immune and endocrine systems, and brain activity, positively affecting performance. …”
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866
Substandard Language Phenomena in Artistic Discourse
Published 2025-12-01“…The substandard is currently becoming a source of replenishment of the stylistically reduced layer of modern colloquial speech.…”
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867
HERGAI: an artificial intelligence tool for structure-based prediction of hERG inhibitors
Published 2025-07-01“…It also demonstrated superior screening power compared to virtual screening schemes that used existing scoring functions. This model, named “HERGAI,” along with relevant input/output data and user-friendly source code, is available in our GitHub repository ( https://github.com/vktrannguyen/HERGAI ) and can be used to predict drug-induced hERG blockade, even on large data sets.…”
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868
Pathoadaptive Mutations of Escherichia coli K1 in Experimental Neonatal Systemic Infection.
Published 2016-01-01“…Only four single nucleotide polymorphisms (SNPs), in genes (gloB, yjgV, tdcE) or promoters (thrA) involved in metabolic functions, were found: no changes were detected in genes encoding virulence determinants associated with the invasive potential of E. coli K1. …”
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869
Spontaneous blinking and brain health in aging: Large-scale evaluation of blink-related oscillations across the lifespan
Published 2025-01-01“…Crucially, these age-related differences were not observed in the behavioral measures of task performance such as reaction time and accuracy, suggesting that blink-related neural responses during the target detection task are more sensitive in capturing aging-related brain function changes compared to behavioral measures alone. …”
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870
Extracting Filaments Based on Morphology Components Analysis from Radio Astronomical Images
Published 2019-01-01“…MCA uses a dictionary whose elements can be wavelet translation function, curvelet translation function, or ridgelet translation function to decompose images. …”
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871
Combining dopamine and glucose sensings on paper devices for the metabolic study of neurosecretion
Published 2025-08-01“…Glucose, the main source of energy of the human body, and dopamine, a major neurotransmitter, are two analytes widely investigated in the study of the brain. …”
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872
Wireless, Battery‐free, Implantable Inductor‐Capacitor Based Sensors
Published 2025-07-01“…Inductor‐capacitor (LC) sensors offer a compelling alternative that uses simple resonant circuits to achieve battery‐free and wireless operation. These sensors function through magnetic coupling with external readers, eliminating the need for internal power sources or physical connections, while enabling compact and biocompatible designs. …”
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873
Microparticles That Form Immune Complexes as Modulatory Structures in Autoimmune Responses
Published 2015-01-01“…Initially MPs were considered to be inert cellular products with no biological function. However, an extensive research and functional characterization have shown that the molecular composition and the effects of MPs depend upon the cellular background and the mechanism inducing them. …”
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874
Cell fate analysis of embryonic ventral mesencephalic grafts in the 6-OHDA model of Parkinson's disease.
Published 2012-01-01“…To investigate this further, we used a GFP reporter mouse as source of VM tissue that enabled the detection and dissection of the grafts 6 weeks post implantation. …”
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875
Research and application of image recognition-based identification for flesh browning of loquat fruits
Published 2025-02-01“…Additionally, the MATLAB ROI function was used to select the irregular representative loquat flesh browning areas, extract the color feature value, and complete the browning area segmentation of the original image by using the Euclidean distance. …”
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876
A GD-PSO Algorithm for Smart Transportation Supply Chain ABS Portfolio Optimization
Published 2021-01-01“…In this article, a penalty function based on graph density (GD) was introduced to the particle swarm optimization algorithm (PSO), and a GD-PSO algorithm was proposed. …”
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877
Rare pediatric retinal diseases: A review
Published 2025-05-01“…Additionally, references from these sources were reviewed and included if they provided pertinent information on the topic. …”
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878
Species-level enumeration of low-concentration lactic acid bacteria in breast milk
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879
Subjective and objective vestibular changes that occur following paediatric cochlear implantation: systematic review and meta-analysis
Published 2019-05-01“…Grey literature and unpublished sources were also reviewed. Study selection Articles published from 1980 until the present which documented pre-operative and post-operative vestibular testing on children under the age of 18 were used. …”
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880
Organics in the stratosphere: new insights from weather balloon flights conducted in France
Published 2025-06-01“…Activated and functionalized carbon fabrics were used to target chemical compounds in the gaseous and aerosol forms during three flights over France. …”
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