Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells. by Ryan D Huff, Alan C-Y Hsu, Kristy S Nichol, Bernadette Jones, Darryl A Knight, Peter A B Wark, Philip M Hansbro, Jeremy A Hirota

“…<h4>Introduction</h4>The airway epithelium is a physical and immunological barrier that protects the pulmonary system from inhaled environmental insults. Uric acid has been detected in the respiratory tract and can function as an antioxidant or damage associated molecular pattern. …”
Get full text

Experimental Study of Coherent Collaborative Processing Method in Distributed Automotive Radar by A. A. Kuzin, S. E. Kuznetsov, A. V. Miakinkov, R. S. Fadeev, S. A. Shabalin

“…Intelligent driver assistance systems are increasingly employing radar systems to detect, resolve, and track various classes of targets. …”
Get full text

Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis. by Pei-Hsuan Weng, Yi-Ling Huang, John H Page, Jen-Hau Chen, Jianfeng Xu, Stella Koutros, Sonja Berndt, Stephen Chanock, Meredith Yeager, John S Witte, Rosalind A Eeles, Douglas F Easton, David E Neal, Jenny Donovan, Freddie C Hamdy, Kenneth R Muir, Graham Giles, Gianluca Severi, Jeffrey R Smith, Carmela R Balistreri, Irene M Shui, Yen-Ching Chen

“…<h4>Background</h4>Toll-like receptor 4 (TLR4) is one of the best known TLR members expressed on the surface of several leukocytes and tissue cells and has a key function in detecting pathogen and danger-associated molecular patterns. …”
Get full text

A juxtamembrane basolateral targeting motif regulates signaling through a TGF-β pathway receptor in Drosophila. by Aidan J Peterson, Stephen J Murphy, Melinda G Mundt, MaryJane Shimell, Edward B Leof, Michael B O'Connor

“…Wit, a second Type II receptor, shows a markedly different behavior, with the protein detected on all membrane regions but enriched at the apical side. …”
Get full text

Intercropping and Nitrogen Fertilization Altered the Patterns of Leaf Senescence in Sorghum by Peter E. Moi, Onesmus M. Kitonyo, George N. Chemining’wa, Josiah M. Kinama

“…Effects of competition in sorghum-legume intercropping and source-sink relationships on the patterns of leaf senescence deserve further investigation.…”
Get full text

Implementation of a Neural Network for Adaptive PID Tuning in a High-Temperature Thermal System by Juan Carlos Almachi, Ramiro Vicente, Edwin Bone, Jessica Montenegro, Edgar Cando, Salvatore Reina

“…Implemented on an 18 kW retrofitted Blue-M furnace, the system was characterized by second-order transfer functions for heating and forced convection cooling. …”
Get full text

Partial Purification of <i>Bacillus cereus</i> Enzyme Expression for Bio-Pulping of Lignin Degraders Isolated from <i>Coptotermus curvignathus</i> by Sharfina Mutia Syarifah, Ashuvila Mohd Aripin, Nadiah Ishak, Nosa Septiana Anindita, Mohd Firdaus Abdul-Wahab, Angzzas Sari Mohd Kassim

“…Despite extensive research on <i>Bacillus</i> sp. as lignin degraders, the enzyme mechanisms involved, particularly in <i>Bacillus cereus</i> isolated from termite guts, remain unclear. In this study, the selected Bacillus cereus was fermented to extract the lignin-degrading enzymes to identify the enzymes responsible for lignin degradation using the sample substrate empty fruit bunch (EFB) as their sole carbon source. …”
Get full text

Computational exploration of global venoms for antimicrobial discovery with Venomics artificial intelligence by Changge Guan, Marcelo D. T. Torres, Sufen Li, Cesar de la Fuente-Nunez

“…From these, we identified 386 candidates that are structurally and functionally distinct from known antimicrobial peptides. …”
Get full text

Recent Advances and Challenges in the Production of Hydroxylated Natural Products Using Microorganisms by Chang Sun, Rumei Zeng, Tianpeng Chen, Yibing Yang, Yi Song, Qiang Li, Jie Cheng, Bingliang Liu

“…Hydroxylation reaction is a significant source of structural diversity in natural products (NPs), playing a crucial role in improving the bioactivity, solubility, and stability of natural product molecules. …”
Get full text

DistB-Condo: Distributed Blockchain-Based IoT-SDN Model for Smart Condominium by Anichur Rahman, Md. Jahidul Islam, Ziaur Rahman, Md. Mahfuz Reza, Adnan Anwar, M. A. Parvez Mahmud, Mostofa Kamal Nasir, Rafidah Md. Noor

“…Condominium network refers to intra-organization networks, where smart buildings or apartments are connected and share resources over the network. Secured communication platform or channel has been highlighted as a key requirement for a reliable condominium which can be ensured by the utilization of the advanced techniques and platforms like Software-Defined Network (SDN), Network Function Virtualization (NFV) and Blockchain (BC). …”
Get full text

Composition of the culturable bacterial community associated with the water column and soft tissues from oysters of the mangrove ecosystem at Honda Swamp, Colombian Caribbean by Lersy López Gutiérrez, Martha Torres, Esteban Zarza González, Alejandro Henao Castro, Laura Contreras Vega

“…Microbiological activity is the basis of ecosystems functioning, among these are the mangroves, which offer a wide variety of goods and services to humanity. …”
Get full text

A Rare Encounter: Gastric Ulcer Penetration into the Splenic Hilum Presenting with Upper Gastrointestinal Bleeding and a Massive Splenic Haematoma—Case Report and Literature Review... by Ioana-Irina Rezuș, Vasile-Claudiu Mihai, Diana Elena Floria, Andrei Olteanu, Vlad Ionut Vlasceanu, Radu Petru Soroceanu, Alin Constantin Pinzariu, Brigitta Teutsch, Sergiu Tudose-Timofeiov

Get full text

Optimisation of Ultrasound-Assisted Extraction Conditions Using Response Surface Methodology and Identification of Thymoquinone from Black Cumin (Nigella sativa L.) Seed Extract§ by Nita Kaushik, Aradhita Barmanray

“…The presence of thymoquinone was further confirmed by the functional groups detected in FTIR analysis. Under the specified extraction conditions, total phenolic content (TPC, expressed as gallic acid equivalents), yield (in %) and DPPH radical scavenging activity increased by approx. 271.03 mg/g, and 4.5 and 83.06 %, respectively. …”
Get full text

Harnessing Hemp (<i>Cannabis sativa</i> L.) Seed Cake Proteins: From Concentrate Production to Enhanced Choux Pastry Quality by Tatiana Capcanari, Eugenia Covaliov, Cătălina Negoița

“…This study explores the production and valorization of hemp seed cake protein concentrate (HPC) as a functional ingredient to enhance the nutritional quality and sensory attributes of choux pastry products, specifically éclairs. …”
Get full text

The TOR kinase pathway is relevant for nitrogen signaling and antagonism of the mycoparasite Trichoderma atroviride. by Rossana Segreto, Hoda Bazafkan, Julia Millinger, Martina Schenk, Lea Atanasova, Maria Doppler, Christoph Büschl, Mélanie Boeckstaens, Silvia Soto Diaz, Ulrike Schreiner, Fabiano Sillo, Raffaella Balestrini, Rainer Schuhmacher, Susanne Zeilinger

“…Here we describe how alteration of the activity of TOR1, the single and essential TOR kinase of T. atroviride, by treatment with chemical TOR inhibitors or by genetic manipulation of selected TOR pathway components affected various cellular functions. …”
Get full text

Transcriptional profiling of nitrogen fixation and the role of NifA in the diazotrophic endophyte Azoarcus sp. strain BH72. by Abhijit Sarkar, Barbara Reinhold-Hurek

“…Moreover, the NifA regulon in strain BH72 appears to encompass a wider range of cellular functions beyond the regulation of nif genes.…”
Get full text

Staged approach to bilateral severe carotid stenosis: a case report and literature review by Heitor Cabral Frade, Manmeet Kaur, Julia Aigbogun, Muhammad Zeeshan Memon, Arun Chhabra, Akm Muktadir, Hashem Shaltoni

“…Hyperperfusion syndrome (HPS), with or without associated intracerebral hemorrhage, although rare, is a major source of morbidity and mortality after carotid interventions, especially in the setting of bilateral CAD. …”
Get full text

Range Space and Similarity Transformation Using Symbolic Mathematics in Python by Chainarong Wisassakwichai, Prasert Phaochoo

“…The effectiveness of these classes has been validated through numerical results, which, when compared to MATLAB functions (null(), pinv(), sym(), and jordan()), demonstrate that the exact symbolic solutions from both classes significantly improve numerical precision for selected application examples from numerical algorithms, power systems and linear algebra. …”
Get full text

Comparative Analysis of Hydration Status and Microbial Quality of Tap Water Between Urban and Rural Settings in the Ashanti Region of Ghana by Marina A. Tandoh, Priscilla Owusu, Claire-Rush N. A. Nkrumah, Veronica Tawiah Annaful, Chris Y. Asare, Samuel Selorm Attu

“…Six taps were randomly selected at each site in triplicates, resulting in 36 water samples. …”
Get full text

Design and Testing of a Small-Scale Composting Facility for Sheep Manure Utilizing Aeration and Thermal Treatment by Jian Wang, Kailin Ren, Longfei Zhang

“…This unit, tailored for small farms and individual farmers, integrates critical functions such as ventilation, heating, and turning. …”
Get full text