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1801
The global, regional, and national brain and CNS cancers burden and trends from 1990 to 2021
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1802
There is no transfer of mitochondria from donor hematopoietic cells to recipient mesenchymal stromal cells after allogeneic hematopoietic stem cells transplantation in humans
Published 2025-07-01“…Mitochondria, which can be transferred between cells via nanotubes or extracellular vesicles, play a key role in the functions of mesenchymal stromal cells. In a murine model, donor hematopoietic stem and progenitor cells transfer functional mitochondria to bone marrow mesenchymal stromal cells of the recipient. …”
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1803
Stealth missiles with precision guidance: A novel multifunctional nano-drug delivery system based on biomimetic cell membrane coating technology
Published 2025-08-01“…This approach enables nanocarriers to inherit the intrinsic biological properties of different cell sources, endowing them with immune evasion, prolonged circulation, dynamic targeting, biocompatibility, and biodegradability, while supporting the integration of diverse biomedical functions. …”
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1804
A novel deep learning technique for multi classify Alzheimer disease: hyperparameter optimization technique
Published 2025-04-01“…A progressive brain disease that affects memory and cognitive function is Alzheimer’s disease (AD). To put therapies in place that potentially slow the progression of AD, early diagnosis and detection are essential. …”
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1805
Medicinal Phytocompounds as Potential Inhibitors of p300-HIF1α Interaction: A Structure-Based Screening and Molecular Dynamics Simulation Study
Published 2025-04-01“…<b>Background:</b> Hypoxia plays a key role in cancer progression, mainly by stabilizing and activating hypoxia-inducible factor-1 (HIF-1). For HIF-1 to function under low oxygen conditions, it must interact with the transcriptional coactivator p300, a critical step for promoting cancer cell survival and adaptation in hypoxic environments. …”
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1806
The synthesis of the Gospel and life as a goal of evangelization
Published 2024-06-01“…In implementing the priestly function, the focus was on celebrating the Eucharist, revealing it as a source of human strength and energy, a school of sacramental perception of life and appreciation of matter, as well as a space for forming a new man. …”
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1807
(...) będę czągał sankie szniegem (...). Głosy dzieci z Domu Sierot
Published 2024-01-01“…Selected quotations illustrate functioning of the children of the Orphans’ Home in the Polish-Jewish borderland, as well as related struggles and dilemmas, primarily on the linguistic and identity levels. …”
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1808
Structural Repetition Detector for multi-scale quantitative mapping of molecular complexes through microscopy
Published 2025-07-01“…Understanding these structures provides insights into their functional roles. While super-resolution microscopy can visualise such patterns, manual detection in large datasets is challenging and biased. …”
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1809
GENERATION AND COLLECTION OF TOBACCO AEROSOL FOR SHISHA
Published 2020-11-01“…Qualitative characteristics of tobacco aerosol for shisha are determined by the functional purpose and depend on the component composition of the tobacco mixture and the coal used.The purpose of the research is to develop a methodology for the comprehensive assessment of tobacco for shisha based on modern methods of product quality control and includes the following steps:- monitoring of the studies to determine the component composition of the hookah mixture and the aerosol produced;- analysis of hookah mixture testing modes and development of an aerosol generation protocol;- development of a method for collecting aerosol on a laboratory smoking machine; - quantitative analysis of toxic analytes by HPLC MS / MS method.Methods have been developed for the machine generation and collection of tobacco aerosol for hookah, taking into account low concentrations of the analyzed toxic substances.The expediency of using the HPLC MS / MS method to determine the quantity of the following substances in tobacco aerosol for shisha has been substantiated:- carbonyl compounds (formaldehyde, acetaldehyde, acrolein) by detection on an electrospray source in the negative polarity mode- tobacco specific nitrosoamines (NNN and NNK) by detection on an electrospray source in the positive polarity mode.During the research laboratory and analytical equipment was used: a five-channel linear CERULEAN SM 405 smoking machine; Thermo Scientific Dionex UltiMate 3000 liquid chromatograph and TSQ Quantiva mass spectrometer.Obtaining experimental data on the quantitative determination of the component composition of the aerosol produced by tobacco for shisha using hookah systems is relevant for assessing toxic characteristics of the product.…”
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1810
Quand l’écriture entre dans le quotidien : les mots de la mémoire dans les livres de raison (Provence, fin xve-xviiie siècles)
Published 2025-05-01“…This lexicon is correlated with the functions of memory aids and records (these books of reason could be used as evidence in court), which allows us to question the way words and signs functioned in memory techniques (repetitions, reformulations, mnemonic use of genealogies, reference to historical events, etc.) developed by scribblers often unfamiliar with the learned “arts of memory”. …”
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1811
Risks as an object of internal control: identification and assessment
Published 2021-08-01“…The main purpose of internal control is to ensure timely detection and analysis of business risk, reliability of relevant information, integrity of assets, compliance with regulations, internal policies and procedures, implementation of plans and efficient use of resources. …”
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1812
Pediatric Adenotonsillectomy Trial for Snoring (PATS): protocol for a randomised controlled trial to evaluate the effect of adenotonsillectomy in treating mild obstructive sleep-di...
Published 2020-03-01“…The study’s coprimary endpoints are (1) change from baseline in executive behaviour relating to self-regulation and organisation skills as measured by the Behavioural Rating Inventory of Executive Function (BRIEF) Global Composite Score (GEC); and (2) change from baseline in vigilance as measured on the Go-No-Go (GNG) signal detection parameter (d-prime). …”
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1813
BIOINFORMATICS — INSTRUMENT INTERPRETATION PROTEOMIC PROFILES OF MEAT PROTEIN
Published 2017-04-01“…Studies in this field have enabled formulating and significantly expanding the approaches to the identification and quantification of protein markers of quality, functionality and safety of meat raw material (detection of falsification) in the finished meat products. …”
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1814
Emerging Diagnostic Approaches for Musculoskeletal Disorders: Advances in Imaging, Biomarkers, and Clinical Assessment
Published 2025-06-01“…Point-of-care ultrasound and portable diagnostic devices have expanded real-time imaging and functional assessment capabilities across diverse clinical settings. …”
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1815
Immunoexpression of tumor suppressor genes p53, p21WAF1/CIP1 and p27KIP1 in humam astrocystic tumors Imuno-expressão dos genes supressores tumorais p53, p21WAF1/CIP1 e p27KIP1 em t...
Published 2007-12-01“…These results indicated the p53 mutation as an initial, relevant and potentially predictor of tumor progression event in astrocytomas, with the detection of p21 protein as an important resource for the deduction of functional situation of this gene. …”
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1816
Net2Brain: a toolbox to compare artificial vision models with human brain responses
Published 2025-05-01“…Finally, the toolbox integrates seamlessly with other established open source libraries, enhancing interoperability and promoting collaborative research. …”
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1817
Nature-based solutions for urban climate resilience: implementation, contribution, and effectiveness
Published 2025-12-01“…For instance, of the 26 qualitative sample publications selected for this systematic review, almost 54 % employed only secondary data sources, and eight publications lacked clear and specified data analysis techniques. …”
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1818
Ashbya gossypii as a versatile platform to produce sabinene from agro-industrial wastes
Published 2024-10-01“…Conclusions Engineered A. gossypii strains serve as a suitable platform for assessing plant terpene synthase functionality and substrate selectivity in vivo, which are crucial to understand monoterpene bioproduction. …”
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1819
Thermal Characteristics Testing and Analysis of Dry Gear Hobbing Machine on Multivariate Information Fusion
Published 2024-01-01“…Through the selection of hardware for the lower computer, the development of software functions for the upper computer, and the integration of test functions, the multi-source fusion test method for the thermal characteristics of dry-cutting and hobbing machine was constructed. …”
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1820
„Looduse universaal-biblioteek“: raamatusarja juhtumiuuring / Universal Library by Loodus (1927–1931): a case study of the book series
Published 2024-06-01“…The series significantly expanded the selection of translated authors, making it a tool for introducing translated literature and new writers and fostering opportunities for emerging translators. …”
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