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2941
Targeted proteomics for absolute quantification of glucose transporter 1 in mammalian brain cells using liquid chromatography-mass spectrometry
Published 2025-05-01“…Glucose represents a major source of energy for mammalian brains. Its uptake is tributary to a functional glucose transporter (GLUT1) expression at the blood-brain barrier (BBB). …”
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2942
Effects of aspirin and omega-3 fatty acids on age-related macular degeneration in ASCEND-Eye: a randomised placebo-controlled trial in a population with diabetes
Published 2025-02-01“…Reports of AMD diagnoses were sourced from 6 monthly ASCEND follow-up questionnaires and a Visual Function Questionnaire.Participants 15 480 UK adults at least 40 years of age with diabetes but no evident cardiovascular disease.Interventions 100 mg aspirin daily versus placebo and, separately, 1 g omega-3 FAs daily versus placebo.Main outcome measure The first post-randomisation reports of AMD.Results During 7.4 years of follow-up, 122 (1.6%) participants randomised to aspirin were reported as having AMD, compared with 138 (1.8%) randomised to placebo (rate ratio 0.88; 95% CI 0.69 to 1.12; p=0.31). …”
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2943
Repair of aircraft engine parts made of heat-resistant nickel alloys using additive plasma technologies
Published 2024-10-01“…No wear of the labyrinth ridges or cracks was detected. The functionality of the restored disk has been confirmed. …”
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2944
Exploring Autophagy-Related Gene Expression in Hepatocellular Carcinoma via TCGA, GEPIA2, and HPA Databases: Implications for Prognosis
Published 2025-07-01“…RT-qPCR analysis further confirmed significant upregulation of mRNA expression levels of randomly selected BAG3, EIF2AK2, KIF5B, and RAB24 in HCC cell lines, consistent with the bioinformatics analysis findings.Conclusion: This study showed that the 41 obtained ARGs, such as ATG16L1, ATG4B, BAG3, KIF5B, MAPK1, RAB24, and SOGA1, these findings suggest that ARGs may serve as prognostic biomarkers for HCC, warranting further validation in clinical cohorts and functional studies.Keywords: hepatocellular carcinoma, bioinformatics, autophagy, prognostic markers, TCGA…”
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2945
Humic acids as drivers of plant growth: regulating root development and photobiology through redox modulation
Published 2025-05-01“…Abstract Background Humic acids (HA) influence plant growth and development through various mechanisms that depend on the source and concentration of HA, as well as the specific plant organ and its developmental stage. …”
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2946
Simulation Analysis of Water Resource Scheduling in Nansu River Based on Coupled Water Quality-Quantity Model
Published 2025-06-01“…Conducting research on water quality and quantity in rivers that flow through urban areas and serve functions such as water supply and irrigation, and implementing rational scheduling, is of significance for ensuring a healthy aquatic ecosystem and enhancing the well-being of local residents. …”
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2947
Unlocking health insights: exploring intention to adopt district health information systems in Bahir Dar City, northwest Ethiopia
Published 2025-02-01“…BackgroundDistrict Health Information System version 2 (DHIS2) is an open-source platform designed for data collection, processing, analysis, and visualization within healthcare systems. …”
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2948
Methods for Adaptive Transformation of Content in Hypertext Format on Corporate TV and Information Kiosks of Educational Institutions
Published 2024-07-01“…The article also discusses how to level out the nuances associated with different resolutions of graphic images and screen orientation.Conclusion: the final paragraphs of the article conclude on the nuances of the functioning of the developed system, the effectiveness of which directly depends on methods of implementation and technologies used, chosen and discussed in the article. …”
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2949
An Evaluation of the Possibility of Using Buckwheat Hulls as an Addition to Bread
Published 2024-02-01“…Due to the high nutritional value of buckwheat hulls, which can be a great source of fibre, phenolics, minerals and some vitamins, the aim of the study was to assess the possibility of using it as a functional addition in bread production. …”
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2950
PEDAGOGICAL CONTENT THREE-FACTOR MODEL OF EDUCATING HIGH-SCHOOL STUDENTS FOR PROFESSIONAL ACTIVITIES
Published 2016-09-01“…Due to this system, foreign language becomes a source of professionally demanded and personally valuable information. …”
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2951
The cnf1 gene is associated with an expanding Escherichia coli ST131 H30Rx/C2 subclade and confers a competitive advantage for gut colonization
Published 2022-12-01“…In addition, functional analysis of the cnf1-positive clinical strain EC131GY ST131-H30Rx/C2 and a cnf1-deleted isogenic strain showed no detectable impact of the CNF1 gene on bacterial fitness and inflammation during the acute phase of bladder monoinfection. …”
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2952
Predicting the course of localized periodontitis of traumatic etiology after complex treatment
Published 2024-03-01“…To assess the body’s adaptive resources, the entropy of the leukocyte blood count was calculated, and risk factors for the occurrence of LPT were assessed. …”
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2953
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2954
Graphical representation of global water models
Published 2025-04-01“…Global water models are used to simulate the terrestrial part of the global water cycle, and their outputs contribute to the evaluation of important natural and societal issues, including water availability, flood risk, and ecological functioning. Whilst global water modeling is an area of science that has developed over several decades, and individual model-specific descriptions exist for some models, there has to date been no attempt to visualize the ways that several models work, using a standardized visualization framework. …”
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2955
Bioinformatics-driven exploration of key genes and mechanisms underlying oxidative stress in traumatic brain injury
Published 2025-04-01“…This study aims to elucidate the potential molecular interactions between key genes associated with oxidative stress and their influence on TBI pathogenesis.MethodsTBI dataset and oxidative stress-related genes sourced from Public databases. Differential expression analysis and machine learning models were executed to select key genes, which were further validated using receiver operating characteristic (ROC) curves. …”
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2956
Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov...
Published 2025-07-01“…A contrasting pattern was detected for the gene expression of cytochrome c oxidase subunit 4I1 (COX4I1), with stable levels in CON and a downregulation in CAR due to LPS injection. …”
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2957
Genome‐wide association study and BSR‐seq identify nitrate reductase–related genes in rice landraces (Oryza sativa L.)
Published 2025-06-01“…In this study, genome‐wide association studies were used to detect nitrate reductase (NR)‐related loci in 419 rice landraces. …”
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2958
Thermophilic microbial agents promote the fermentation progression of spent mushroom compost and pig manure
Published 2025-06-01“…Overall, the application of thermophilic microbial agents not only extended the high temperature phase of composting by over 30% and shortened the composting cycle by 50%, but more importantly, it achieved comprehensive improvement in compost quality by selectively enriching functional microbial communities such as Pseudomonas. …”
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2959
Degradation of Tetracycline in Wastewater by Persulfate Activated by Sulfidated Nanometer Zero-valent Iron
Published 2024-07-01“…The primary pathways of TC degradation involve specific functional group cleavage and ring-opening reactions, ultimately leading to oxidative degradation into CO<sub>2</sub> and H<sub>2</sub>O.…”
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2960
Prediction of Alzheimer’s Disease Based on Multi-Modal Domain Adaptation
Published 2025-06-01“…<b>Background/Objectives:</b> Structural magnetic resonance imaging (MRI) and 18-fluoro-deoxy-glucose positron emission tomography (PET) reveal the structural and functional information of the brain from different dimensions, demonstrating considerable clinical and practical value in the computer-aided diagnosis of Alzheimer’s disease (AD). …”
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