Comparison of intramedullary nailing and minimal invasive plate osteosynthesis in the treatment of simple intra-articular fractures of the distal tibia (AO-OTA type 43 C1-C2) by Ozan Beytemür, Alican Barış, Cem Albay, Serdar Yüksel, Sever Çağlar, Ender Alagöz

“…Objective: The aim of this study was to compare midterm functional and radiographic results of minimal invasive plate osteosynthesis (MIPO) with intramedullary nailing (IMN) of simple intra-articular distal tibial fractures (AO-OTA type 43 C1-C2). …”
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A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells. by Jin-Bon Hong, Fu-Ju Chou, Amy T Ku, Hsiang-Hsuan Fan, Tung-Lung Lee, Yung-Hsin Huang, Tsung-Lin Yang, I-Chang Su, I-Shing Yu, Shu-Wha Lin, Chung-Liang Chien, Hong-Nerng Ho, You-Tzung Chen

“…PiggyBac is a prevalent transposon system used to deliver transgenes and functionally explore the mammalian untouched genomic territory. …”
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Equine pegiviruses cause persistent infection of bone marrow and are not associated with hepatitis. by Joy E Tomlinson, Raphael Wolfisberg, Ulrik Fahnøe, Himanshu Sharma, Randall W Renshaw, Louise Nielsen, Eiko Nishiuchi, Christina Holm, Edward Dubovi, Brad R Rosenberg, Bud C Tennant, Jens Bukh, Amit Kapoor, Thomas J Divers, Charles M Rice, Gerlinde R Van de Walle, Troels K H Scheel

“…The polyprotein consensus sequences did not change, suggesting that both clones were fully functional. To our knowledge, this is the first successful extrahepatic viral RNA launch and the first robust reverse genetics system for a pegivirus. …”
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Development and validation of a set of novel and robust 4-lncRNA-based nomogram predicting prostate cancer survival by bioinformatics analysis. by Peng Zhang, Xiaodong Tan, Daoqiang Zhang, Qi Gong, Xuefeng Zhang

“…Possible biological functions for those prognostic lncRNAs were predicted on those 4 protein-coding genes (PCGs) related to lncRNAs.…”
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Altered BOLD response during inhibitory and error processing in adolescents with anorexia nervosa. by Christina Wierenga, Amanda Bischoff-Grethe, A James Melrose, Emily Grenesko-Stevens, Zoë Irvine, Angela Wagner, Alan Simmons, Scott Matthews, Wai-Ying Wendy Yau, Christine Fennema-Notestine, Walter H Kaye

“…However, the degree to which these functional brain alterations are related to disease state and whether error processing is altered in AN individuals is unknown.…”
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Genome, transcriptome and secretome analyses of the antagonistic, yeast-like fungus Aureobasidium pullulans to identify potential biocontrol genes by Maria Paula Rueda-Mejia, Lukas Nägeli, Stefanie Lutz, Richard D. Hayes, Adithi R. Varadarajan, Igor V. Grigoriev, Christian H. Ahrens, Florian M. Freimoser

“…Aureobasidium pullulans is an extremotolerant, cosmopolitan yeast-like fungus that successfully colonises vastly different ecological niches. …”
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Development of a novel anti-human glypican 5 monoclonal antibody (G5Mab-1) for multiple applications by Yu Kaneko, Tomohiro Tanaka, Shiori Fujisawa, Guanjie Li, Hiroyuki Satofuka, Mika K. Kaneko, Hiroyuki Suzuki, Yukinari Kato

“…Therefore, the development of versatile and specific anti-GPC5 monoclonal antibodies (mAbs) is desired to clarify the biological and pathological functions of GPC5. In this study, we successfully established an anti-human GPC5 mAb (clone G5Mab-1) using the Cell-Based Immunization and Screening method. …”
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Unveiling molecular mechanisms of pigment synthesis in gardenia (Gardenia jasminoides) fruits through integrative transcriptomics and metabolomics analysis by Kangqin Li, Lixin Yu, Liqin Gao, lingzhi Zhu, Xiaotao Feng, Shaoyong Deng

“…Functional diversity was clarified by the Clusters of Orthologous Groups (COG) classification, which focused mainly on pigment synthesis functions. …”
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Molecular surveillance of artemisinin resistance-linked PFK13 gene polymorphisms in Adamawa State, Nigeria by Mahmoud Suleiman Jada, Yusuf Umar, Aliyu Abdullahi Pela, Auwal Adamu, Hauwa Ahmed Zailani, Abdullahi Usman Wurochekke

“…Extraction and amplification of Pfk13 gene were successful in 163 samples (67.92%). Out of 163 successfully amplified samples, no validated mutations linked to artemisinin resistance were found, but the A578S mutation was detected in 15.09% of the analyzed samples. …”
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Robotic resection of ectopic mediastinal parathyroid adenoma in multiple endocrine neoplasia 1 by Yuko Ohara, Yuka Kadomatsu, Toyone Kikumori, Toyofumi F. Chen-Yoshikawa

“…Therefore, identifying the locations of all functional glands is crucial for precise resection. …”
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Actuation and Control of Railcar-Mounted Sensor Systems by Caroline Craig, Mehdi Ahmadian

“…The feasibility of a deployable sensor system was successfully assessed by creating and demonstrating a functional prototype mounting assembly that can be used with future automated inspection systems. …”
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Clinical Course and Results of Anti-VEGF Therapy of Retinopathy of Prematurity by L. A. Katargina, E. N. Demchenko, L. V. Kogoleva

“…The clinical course of active retinopathy after anti-VEGF therapy, the possibility and timing of recurrence of the disease, anatomical and functional outcomes of treatment are widely discussed in the press, not fully studied and relevant.Purpose: to study the clinical course of active retinopathy of prematurity after anti-VEGF therapy and clinical and functional outcomes.Patients and Methods. …”
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The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study. by Leila Dorling, Siddhartha Kar, Kyriaki Michailidou, Louise Hiller, Anne-Laure Vallier, Susan Ingle, Richard Hardy, Sarah J Bowden, Janet A Dunn, Chris Twelves, Christopher J Poole, Carlos Caldas, Helena M Earl, Paul D P Pharoah, Jean E Abraham

“…Patients with high breast cancer risk scores experienced less neutropenia compared to those with low risk scores (adjusted p-value = 0.06). Exploratory functional pathway analysis was performed and no functional pathways driving this trend were identified. …”
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Anti-corruption management in the health care system: the legal aspect by М. А. Anishchenko

“…Analyzing the current legal acts, anti-corruption management includes the following main areas of activity (functions): determination of the person (unit) responsible for preventing and detecting corruption in the health care establishment and creating the necessary conditions for its (her) successful work; development and approval of the necessary internal documents on issues of anti-corruption activities, their constant and timely updating; implementation of anti-corruption legislation in other internal documents of the health care institution; realization of corruption risk assessment; ensuring proper prevention and conflict resolution of interests; ensuring openness and transparency of the health care institution's activities; organization of anti-corruption education of employees of the institution of health care; the proper management of information on corruption offenses; maintenance of the necessary registers and databases; control and monitoring of the effectiveness of anti-corruption measures. …”
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Baryogenesis and first-order QCD transition with gravitational waves from a large lepton asymmetry by Fei Gao, Julia Harz, Chandan Hati, Yi Lu, Isabel M. Oldengott, Graham White

“…Abstract A large primordial lepton asymmetry can lead to successful baryogenesis by preventing the restoration of electroweak symmetry at high temperatures, thereby suppressing the sphaleron rate. …”
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Fluorescence spectroscopic profiling of urine samples for predicting kidney transplant rejection by Zhe Yang, Minrui Zhang, Xianduo Li, Zhipeng Xu, Yi Chen, Xiaoyu Xu, Dongdong Chen, Lingquan Meng, Xiaoqing Si, Jianning Wang

“…This research entailed collecting fluorescent fingerprint data from 120 urine samples of post-renal transplant patients using hyperspectral imaging, followed by the development of a learning model to detect various forms of immunological rejection. The model successfully identified multiple rejection types with an average diagnostic accuracy of 95.56 %.Beyond proposing an innovative approach for predicting the risk of complications post-kidney transplantation, this study heralds the potential introduction of a non-invasive, rapid, and accurate supplementary method for risk assessment in clinical practice.…”
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DNA extraction protocols for animal fecal material on blood spot cards. by Ann-Katrin Llarena, Thomas H A Haverkamp, Wenche Støldal Gulliksen, Kristin Herstad, Arne Holst-Jensen, Eystein Skjerve, Lisbeth Rannem, Sabrina Rodriguez-Campos, Øivind Øines

“…Further, the suitability of Illumina shotgun metagenomic sequencing at 20 million paired-end (PE) read depth per sample was assessed on its ability to successfully characterize the taxonomic and functional aspects of the resulting fecal microbiome.…”
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Chartarlactams U-X: Novel Phenylspirodrimanes from a Marine Derived Fungus <i>Stachybotrys</i> sp. SZU-W23 with Anti-Inflammatory Activity Mediated by the NF-κB/ROS Signaling Pathw... by Yanhua Wu, Lanyi Lu, Peng Zhang, Liyan Wang

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Case Report: A case of occult insulinoma localized by [18F] FB (ePEG12)12-exendin-4 positron emission tomography with negative findings of selective arterial calcium stimulation te... by Kentaro Sakaki, Takaaki Murakami, Hiroyuki Fujimoto, Yoichi Shimizu, Kanae Kawai Miyake, Daisuke Otani, Shinya Otsuki, Hironori Shimizu, Kazuyuki Nagai, Takumi Nomura, Daisuke Yabe, Yuji Nakamoto, Nobuya Inagaki

“…We present a clinical case where [18F] FB (ePEG12)12-exendin-4 positron emission tomography/CT (18F-exendin-4 PET/CT) successfully detected insulinoma, unachievable by conventional imaging, underscoring its potential in guiding minimally invasive surgery.Case descriptionA 67-year-old female developed hyperinsulinemic hypoglycemia but could not undergo surgery as conventional imaging methods failed to localize the insulinoma. …”
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Microelectrode Implantation in Human Insula: Technical Challenges and Recording Insights by Daphné Citherlet, Sami Heymann, Maya Aderka, Katarzyna Jurewicz, B. Suresh Krishna, Manon Robert, Alain Bouthillier, Olivier Boucher, Dang Khoa Nguyen

“…Additionally, it provides an avenue to study brain functions by analyzing cerebral responses during neuropsychological paradigms. …”
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