The clinical application of mitoxantrone hydrochloride tracing in endoscopic radical resection of thyroid carcinoma by Xiaozhou Cheng, Lijun Chen, Honggang Zang, Yaping Li

“…Postoperative metrics compared between the two groups included the number of central lymph nodes dissected, the number of metastatic lymph nodes, the incidence of parathyroid gland misdissection, serum parathyroid hormone (PTH) levels, and blood calcium levels. Both groups successfully completed the surgeries. The observation group exhibited a higher number of central lymph nodes dissected and metastatic lymph nodes detected compared to the control group (P < 0.05). …”
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Exenatide Activates the APPL1-AMPK-PPARα Axis to Prevent Diabetic Cardiomyocyte Apoptosis by Lei XiaoTian, Wu QiNan, Gan XiaGuang, Deng WuQuan, Chen Bing, Liang ZiWen

“…Our model of diabetic cardiomyopathy was constructed successfully. After being treated with exenatide, the adiponectin and HMW-adiponectin and the APPL1-AMPK-PPARα axis were increased, the NF-κB and the apoptosis were decreased, the cardiac function of the diabetic rats was improved, and these effects were independent of glucose control.…”
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Identification of biomarkers and target drugs for melanoma: a topological and deep learning approach by Xiwei Cui, Xiwei Cui, Jipeng Song, Qingfeng Li, Jieyi Ren

“…Advanced network analysis tools were employed to identify structural disparities and functional module shifts. Key driver genes were validated through topological centrality metrics. …”
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Natural killer T cell immunotherapy combined with IL-15-expressing oncolytic virotherapy and PD-1 blockade mediates pancreatic tumor regression by Simon Gebremeskel, Adam Nelson, Brent Johnston, Brian D Lichty

“…This results from late detection, high rates of metastasis, and resistance to standard chemotherapies. …”
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Testing and Validation of the Vehicle Front Camera Verification Method Using External Stimulation by Robin Langer, Maximilian Bauder, Ghanshyam Tukarambhai Moghariya, Michael Clemens Georg Eckert, Tibor Kubjatko, Hans-Georg Schweiger

“…Therefore, environmental sensors’ reliability and correct functioning are becoming increasingly important. Current vehicle inspections and self-diagnostics must be adapted to ensure the correct functioning of environmental sensors throughout the vehicle’s lifetime. …”
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Deep sequencing of yeast and mouse tRNAs and tRNA fragments using OTTR by Hans Tobias Gustafsson, Lucas Ferguson, Carolina Galan, Tianxiong Yu, Heather Upton, Ebru Kaymak, Zhiping Weng, Kathleen Collins, Oliver J Rando

“…Taken together, our data confirm the superior performance of OTTR to commercial protocols in analysis of tRNA fragments, and force a reappraisal of potential epigenetic functions of the sperm small RNA payload.…”
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Low dose Adenoviral Vammin gene transfer induces myocardial angiogenesis and increases left ventricular ejection fraction in ischemic porcine heart by Niko Järveläinen, Paavo J. Halonen, Jussi Nurro, Antti Kuivanen, Juho Pajula, Miikka Tarkia, Maria Grönman, Antti Saraste, Johanna Laakkonen, Pyry Toivanen, Tiina Nieminen, Tuomas T. Rissanen, Juhani Knuuti, Seppo Ylä-Herttuala

“…AdVammin treatment also increased ejection fraction at stress in the ischemic heart, as detected using left ventricular cine angiography. In addition, we demonstrated successful in vivo imaging of enhanced angiogenesis using [68Ga]NODAGA-RGD peptide. …”
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Data Mining–Based Model for Computer-Aided Diagnosis of Autism and Gelotophobia: Mixed Methods Deep Learning Approach by Mohamed Eldawansy, Hazem El Bakry, Samaa M Shohieb

“…This comorbidity can significantly impair the quality of life, particularly in adolescents with high-functioning ASD, where the prevalence reaches 41.98%. …”
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Different Commercial Microbial Additives Influence Fermentation Quality and Microbial Community of King Grass Silage by Xianjun Lai, Haiyan Wang, Rui Peng, Zihan Chen, Yuxin Xiang, Lang Yan

“…Additive-treated silages showed improved fermentation quality, simplified bacterial correlation networks, and distinct microbial successions and interactions. A total of 1523 metabolites were detected, with 56–84 significantly altered in each treated group compared to the control. …”
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The noise analysis and multi-physical field coupling study of high-precision SERF atomic gyroscopes by Jiaxin Liu, Xusheng Lei, Yu Yuan, Yizhe Zhou, Haoying Pang, Zhihong Wu

“…Based on the differences in the optical-magnetic response of the dual-axis signals, empirical mode decomposition was used to decompose the dual-axis gyroscope signals into multiple intrinsic mode functions, and Allan deviation analysis was applied to analyze the noise characteristics of the intrinsic mode functions over various periods. …”
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Compensation of Speckle Noise in 2D Images from Triangulation Laser Profile Sensors Using Local Column Median Vectors with an Application in a Quality Control System by Paweł Rotter, Dawid Knapik, Maciej Klemiato, Maciej Rosół, Grzegorz Putynkowski

“…The primary limitation of the proposed method is its applicability only to flat surfaces. Nonetheless, we successfully implemented it in an optical inspection system for the furniture industry, where the post-processed image quality was sufficient to detect surface defects as small as 0.1 mm.…”
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En Bloc Kidney Transplantation, The Best Option? by Mauricio Alejandro Saldaña-Ruiz, Cynthia del Carmen Cardona-Ruiz, Federico Ortiz-Alonso, Mauricio Linnery Rendón-Saldívar

“…Availability of en bloc kidneys was reported, and the transplant was performed successfully. During his post-transplant stay, he showed adequate blood flow by doppler ultrasound with no evidence of thrombosis (Figure 1) and adequate renal function. …”
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Direct mosquito feedings on dengue-2 virus-infected people reveal dynamics of human infectiousness. by Louis Lambrechts, Robert C Reiner, M Veronica Briesemeister, Patricia Barrera, Kanya C Long, William H Elson, Alfonso Vizcarra, Helvio Astete, Isabel Bazan, Crystyan Siles, Stalin Vilcarromero, Mariana Leguia, Anna B Kawiecki, T Alex Perkins, Alun L Lloyd, Lance A Waller, Uriel Kitron, Sarah A Jenkins, Robert D Hontz, Wesley R Campbell, Lauren B Carrington, Cameron P Simmons, J Sonia Ampuero, Gisella Vasquez, John P Elder, Valerie A Paz-Soldan, Gonzalo M Vazquez-Prokopec, Alan L Rothman, Christopher M Barker, Thomas W Scott, Amy C Morrison

“…Magnitude of viremia is the primary determinant of successful human-to-mosquito DENV transmission. People with the same level of viremia, however, can vary in their infectiousness to mosquitoes as a function of other factors that remain to be elucidated. …”
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Interleukin-15 and cancer: some solved and many unsolved questions by Gabriella Pietra, Lorenzo Moretta, Nicola Tumino, Piera Filomena Fiore, Sabina Di Matteo, Francesca Romana Mariotti, Selene Ottonello, Simone Negrini, Barbara Bottazzi, Erwan Mortier, Bruno Azzarone

“…Both forms have been successfully tested in experimental tumor murine models and are currently undergoing investigation in phase I/II clinical trials. …”
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The expression pattern of long non-coding RNA PVT1 in tumor tissues and in extracellular vesicles of colorectal cancer correlates with cancer progression by Kai Guo, Jie Yao, Qiang Yu, Zijian Li, Hu Huang, Jianguo Cheng, Zhigang Wang, Yunfeng Zhu

“…Here, we reported for the first time that PVT1 as a long non-coding RNA was successfully detected in extracellular vesicles excluded from SW620 and SW480 cells, and the expression level of PVT1 was higher in extracellular vesicles from the more aggressive cell SW620 than from SW480. …”
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AI for rapid identification of major butyrate-producing bacteria in rhesus macaques (Macaca mulatta) by Annemiek Maaskant, Donghyeok Lee, Huy Ngo, Roy C. Montijn, Jaco Bakker, Jan A. M. Langermans, Evgeni Levin

“…The model was successful in predicting functional groups, major butyrate producers (AUC 0.75) and a mixed group including fermenters and short-chain fatty acid (SCFA) producers (AUC 0.81). …”
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Correlation and Agreement of Quantitative Flow Ratio With Fractional Flow Reserve in Saphenous Vein Grafts by Ruben W. de Winter, Yvemarie B. O. Somsen, Roel Hoek, Pepijn A. van Diemen, Ruurt A. Jukema, Mathé P. Jonker, Albert C. van Rossum, Jos W. R. Twisk, Rolf A. Kooistra, Jasper Janssen, Sina Porouchani, Adriaan Wilgenhof, Niels J. Verouden, Ibrahim Danad, Johan H. C. Reiber, Alexander Nap, Paul Knaapen

“…A threshold of ≤0.80 was used to define functional significance. QFR was successfully computed in 140 (93%) SVGs. …”
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Plasma FGF2 and YAP1 as novel biomarkers for MCI in the elderly: analysis via bioinformatics and clinical study by Yejing Zhao, Yejing Zhao, Xiang Wang, Jie Zhang, Yanyan Zhao, Yi Li, Ji Shen, Ying Yuan, Jing Li

“…Between October and November 2024, a total of 146 elderly individuals diagnosed with MCI and 54 healthy elderly subjects were successfully recruited. Enzyme linked immunosorbent assay (ELISA) was used to detect plasma hub gene protein concentration. …”
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A Linear Decomposition Method to Analyze and Study Pulsar Mode Changes by Longfei Hao, Zhixuan Li, Faxin Shen, Yonghua Xu, Yuxiang Huang, Kejia Lee, Qingzheng Yu, Hongguang Wang

“…In this paper, we present the linear decomposition method (LDM), which we developed to detect and analyze pulsar profile variations and mode-changing behavior. …”
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Age- and Post-Based Complex Analyses of Heart Rate Variability in Young Male Handball Players for Potential Prevention of Overload-induced Injuries by Zita Petrovszki, Olivér Czimbalmos, Vera Gal, Gabor Korosi, Edit Nagy, Rita Mikulan, Gyongyi Horvath

“…Anthropometric parameters, HR, R-R interval (RRi), root mean square of successive difference of RRi (RMSSD), and its corrected values (by division or multiply with powers of RRi; C_RMSSDs) were analyzed. …”
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