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881
Targeted proteomics for absolute quantification of glucose transporter 1 in mammalian brain cells using liquid chromatography-mass spectrometry
Published 2025-05-01“…Glucose represents a major source of energy for mammalian brains. Its uptake is tributary to a functional glucose transporter (GLUT1) expression at the blood-brain barrier (BBB). …”
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882
Distinct microbial communities drive methane cycling in below- and above-ground compartments of tropical cloud forests growing on peat
Published 2025-05-01“…However, no CH4-cycling functional genes were detected in the stem core samples. …”
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883
Leveraging artificial intelligence for photo identification to aid CITES enforcement in combating illegal trade of the endangered humphead wrasse (Cheilinus undulatus)
Published 2025-03-01“…A Licence to Possess system for CITES is implemented in the city to regulate the quota of live wild-sourced CITES specimens, including humphead wrasse, held at each registered trading premise and ensure traceability through documentation. …”
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884
Optimisation of Ultrasound-Assisted Extraction Conditions Using Response Surface Methodology and Identification of Thymoquinone from Black Cumin (Nigella sativa L.) Seed Extract§
Published 2025-01-01“…The presence of thymoquinone was further confirmed by the functional groups detected in FTIR analysis. Under the specified extraction conditions, total phenolic content (TPC, expressed as gallic acid equivalents), yield (in %) and DPPH radical scavenging activity increased by approx. 271.03 mg/g, and 4.5 and 83.06 %, respectively. …”
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885
Insights into the Driving Factors of Methane Emission from Double-Season Rice Field Under Different Fertilization Practices in South China
Published 2024-11-01“…Paddy fields are the main agricultural source of greenhouse gas methane (CH<sub>4</sub>) emissions. …”
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886
In vitro fermentation of whole matrix, digested products and β-glucan enriched extract of Pleurotus eryngii mushrooms distinctively impact the fecal microbiota of healthy older adu...
Published 2025-06-01“…The changes in bacterial communities upon fermentation at family, genera and species level were detected via 16S rRNA Next Generation Sequencing and Quantitative real-time PCR. …”
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887
Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling
Published 2024-12-01“…These improve the cost-effectiveness of HCL to £163,000 per QALY if it is valued using the EAG preferred source, to £121,000 if it is valued using the same source as NG17 and to £109,000 if it is valued using other credible sources. …”
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888
Pulmonary complications in children and adolescents after allogeneic hematopoietic stem cell transplantation
Published 2022-11-01“…However to date, the effect of HSCT on functional and morphological pulmonary changes in recipients remains insufficiently studied.The objective of current study was to evaluate risk factors affecting long-term survival in children and adolescents after allo-HSCT.Methods and materials. …”
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889
The amino acid composition of Polygonum hydropiper L. and Polygonum persicaria L. herbs of Ukrainian flora
Published 2015-04-01“…The received results testify the promising use of the plant material and will be considered in the future work for the more in-depth study of the selected objects as a source of natural bioactive substances.…”
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890
Differential involvement of neurotransmitter pathways in AD, bvFTD and MCI: Whole-brain MRI analysis
Published 2025-06-01“…Neurotransmitter maps were sourced from JuSpace. We performed volumetric and whole-brain correlation analyses to evaluate relationships between brain regional volumes (BRVs) and neurotransmitter pathways. …”
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891
Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov...
Published 2025-07-01“…Fatty acids, among other substrates, are utilized by immune cells as an energy source. Therefore, L-carnitine, which is authorized as a feed additive in cattle, may influence the metabolism of peripheral blood mononuclear cells (PBMC) during an immune challenge. …”
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892
iMeta Conference 2024: Building an innovative scientific research ecosystem for microbiome and One Health
Published 2024-12-01Get full text
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893
Klebsiella pneumoniae under xylose pressure: the growth adaptation, antimicrobial susceptibility, global proteomics analysis and role of XylA and XylB proteins
Published 2025-04-01“…Additionally, while the growth adaptation of K2044−8Xyl−60G under xylose pressure was confirmed, no amino acid mutations were detected in the functional proteins of this xylose-induced isolate, suggesting that persistent xylose pressure does not cause nonsense mutations in the bacterial genome. …”
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894
Proteomic analysis of plasma unravels dynamic pathways and potential biomarkers indicating disease stages following Mtb infection
Published 2025-08-01“…ABSTRACT Tuberculosis (TB) stages depend greatly on the interaction between Mycobacterium tuberculosis (Mtb) and the host response. As a non-negligible source of active tuberculosis (ATB), individuals with latent Mtb infection (LTBI) are insidious and hard to be detected due to limited biomarkers. …”
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895
HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer
Published 2025-08-01“…A specific immunopeptidomics approach was developed to detect epitopes on human leukocyte antigens (HLA) molecules. …”
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896
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897
Investigating the relationship between the monetary policy shock through the exchange rate channel on the management quality index in the banking system: by examining the productiv...
Published 2025-03-01“…In the present study, we show that replacing ECB balance sheet size with random numbers leads to statistically indistinguishable shock response functions and time series of abnormal monetary policy shocks. …”
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898
Re-use of Building Products in the Netherlands
Published 2019-01-01“…The key findings in this segment were: Organizational The practice of reuse currently functions as an appendix of the demolition industry, bringing benefits as well as disadvantages. …”
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899
Effects of aspirin and omega-3 fatty acids on age-related macular degeneration in ASCEND-Eye: a randomised placebo-controlled trial in a population with diabetes
Published 2025-02-01“…Reports of AMD diagnoses were sourced from 6 monthly ASCEND follow-up questionnaires and a Visual Function Questionnaire.Participants 15 480 UK adults at least 40 years of age with diabetes but no evident cardiovascular disease.Interventions 100 mg aspirin daily versus placebo and, separately, 1 g omega-3 FAs daily versus placebo.Main outcome measure The first post-randomisation reports of AMD.Results During 7.4 years of follow-up, 122 (1.6%) participants randomised to aspirin were reported as having AMD, compared with 138 (1.8%) randomised to placebo (rate ratio 0.88; 95% CI 0.69 to 1.12; p=0.31). …”
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900
Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study
Published 2025-01-01“…Main outcome measures The primary outcome was diagnostic model sensitivity and specificity for detecting bladder outlet obstruction, detrusor underactivity and detrusor overactivity, with 75.0% considered minimum clinically useful performance. …”
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