Pediatric Adenotonsillectomy Trial for Snoring (PATS): protocol for a randomised controlled trial to evaluate the effect of adenotonsillectomy in treating mild obstructive sleep-di... by Rui Wang, Jessie P. Bakker, Ronald D. Chervin, Susan L. Garetz, Fauziya Hassan, Stacey L. Ishman, Ron B. Mitchell, Michael G. Morrical, Syed K. Naqvi, Jerilynn Radcliffe, Emily I. Riggan, Carol L. Rosen, Kristie Ross, Michael Rueschman, Ignacio E. Tapia, H. Gerry Taylor, David A. Zopf

“…The study’s coprimary endpoints are (1) change from baseline in executive behaviour relating to self-regulation and organisation skills as measured by the Behavioural Rating Inventory of Executive Function (BRIEF) Global Composite Score (GEC); and (2) change from baseline in vigilance as measured on the Go-No-Go (GNG) signal detection parameter (d-prime). …”
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The cardiac phospho-proteome during pressure overload in mice by Rhys Wardman, Steve Grein, Jennifer Schwartz, Frank Stein, Joerg Heineke

“…Our analysis highlights significant changes in hypertrophic signalling, metabolic remodelling, contractile function, and the stress response pathways. We present proteomic data from the main cardiac cell types (endothelial cells, fibroblasts and cardiomyocytes) to reveal the cellular localisation of the detected phospho-proteins, offering insights into temporal and site-specific phosphorylation events, facilitating the potential discovery of novel therapeutic targets and biomarkers. …”
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De Novo Assembly of the Polyhydroxybutyrate (PHB) Producer <i>Azohydromonas lata</i> Strain H1 Genome and Genomic Analysis of PHB Production Machinery by Daniele Traversa, Carlo Pazzani, Pietro D’Addabbo, Lucia Trisolini, Matteo Chiara, Marta Oliva, Angelo Marzella, Camilla Mandorino, Carla Calia, Guglielmina Chimienti, Caterina Manzari, Graziano Pesole, Maria Scrascia

“…In addition to the <i>phaCAB</i> operon, single genes ascribable to PhaC and PhaA functions and auxiliary genes were also detected. A comparative genomic analysis of the available genomes of the genus <i>Azohydromonas</i> revealed the presence of <i>phaCAB</i> and auxiliary genes in all <i>Azohydromonas</i> species investigated, suggesting that the PHB production is a common feature of the genus. …”
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The Role of High-mass Stellar Binaries in the Formation of High-mass Black Holes in Dense Star Clusters by Ambreesh Khurana, Sourav Chatterjee

“…Recent detections of gravitational waves from mergers of binary black holes (BBHs) with premerger source-frame individual masses in the so-called upper mass gap, expected due to (pulsational) pair instability supernovae ((P)PISNe), have created immense interest in the astrophysical production of high-mass black holes (BHs). …”
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Targeting GJB4 to inhibit tumor growth and induce ferroptosis in pancreatic cancer by Xiangru Zheng, Wenjun Li, Xiaoli Li, Qianyi Yao, Luquan Zheng, Rongrong Fan, Ping Bie

“…Bioinformatics analysis was conducted to explore the function of GJB4 in PC cells. Changes in ferroptosis in PC cells following GJB4 downregulation were detected by immunofluorescence staining, transmission electron microscopy, and western blotting.ResultsGJB4 expression was found to be upregulated in PC tissues and positively correlated with patient survival. …”
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Thermally radiative water-based hybrid nanofluid with nanoparticles and gyrotactic microorganisms past a stretching surface with convective conditions and porous media by Humaira Yasmin, Rawan Bossly, Fuad S. Alduais, Afrah Al-Bossly, Anwar Saeed

“…The analysis is done via the bvp4c MATLAB function in order to analyze the current model numerically by implementing convective boundary conditions. …”
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Single-cell transcriptomics of vomeronasal neuroepithelium reveals a differential endoplasmic reticulum environment amongst neuronal subtypes by GVS Devakinandan, Mark Terasaki, Adish Dani

“…The AOS comprising the peripheral sensory vomeronasal organ has evolved elaborate molecular and cellular mechanisms to detect chemo signals. To gain insight into the cell types, developmental gene expression patterns, and functional differences amongst neurons, we performed single-cell transcriptomics of the mouse vomeronasal sensory epithelium. …”
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Distinct repertoires of microRNAs present in mouse astrocytes compared to astrocyte-secreted exosomes. by Ana Jovičić, Aaron D Gitler

“…<h4>Background</h4>Astrocytes are the most abundant cell type in the central nervous system (CNS) and secrete various factors that regulate neuron development, function and connectivity. microRNAs (miRNAs) are small regulatory RNAs involved in posttranslational gene regulation. …”
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The Effect of Processing of Hempseed on Protein Recovery and Emulsification Properties by Anne Pihlanto, Markus Nurmi, Nora Pap, Jarkko Mäkinen, Sari Mäkinen

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The classical-to-quantum crossover in the strain-induced ferroelectric transition in SrTiO3 membranes by Jiarui Li, Yonghun Lee, Yongseong Choi, Jong-Woo Kim, Paul Thompson, Kevin J. Crust, Ruijuan Xu, Harold Y. Hwang, Philip J. Ryan, Wei-Sheng Lee

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Regeneration of Two-Walled Infrabony Periodontal Defects in Swine After Buccal Fat Pad-Derived Dedifferentiated Fat Cell Autologous Transplantation by Daisuke Akita, Naoki Tsukimura, Tomohiko Kazama, Rie Takahashi, Yoshiki Taniguchi, Jin Inoue, Ayana Suzuki, Nodoka Tanabe, Keisuke Seki, Yoshinori Arai, Masatake Asano, Shuichi Sato, Yoshiyuki Hagiwara, Koichiro Kano, Masaki Honda, Taro Matsumoto

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Integrated metabolomic and transcriptomic analyses of flavonoid accumulation in different cultivars of Platostoma palustre by Jiankai You, Zhongdong Wang, Lishan Zeng, Yimeng Xia, Ying Lin, Ruoting Zhan, Guifang Zhang

“…Abstract Background Platostoma palustre is a kind of plant resource with medicinal and food value, which has been differentiated into many different varieties after a long period of breeding. …”
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DUALZ—Deep UNCOVER-ALMA Legacy High-Z Survey by Seiji Fujimoto, Rachel Bezanson, Ivo Labbe, Gabriel Brammer, Sedona H. Price, Bingjie Wang, John R. Weaver, Yoshinobu Fudamoto, Pascal A. Oesch, Christina C. Williams, Pratika Dayal, Robert Feldmann, Jenny E. Greene, Joel Leja, Katherine E. Whitaker, Adi Zitrin, Sam E. Cutler, Lukas J. Furtak, Richard Pan, Iryna Chemerynska, Vasily Kokorev, Tim B. Miller, Hakim Atek, Pieter van Dokkum, Stéphanie Juneau, Susan Kassin, Gourav Khullar, Danilo Marchesini, Michael Maseda, Erica J. Nelson, David J. Setton, Renske Smit

“…We also detect a marginal dust emission from an X-ray-detected galaxy at z _spec = 10.07, suggesting an active coevolution of the central black hole and its host. …”
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Platinum-Induced Ototoxicity in Pediatric Cancer Patients: A Comprehensive Approach to Monitoring Strategies, Management Interventions, and Future Directions by Antonio Ruggiero, Alberto Romano, Palma Maurizi, Dario Talloa, Fernando Fuccillo, Stefano Mastrangelo, Giorgio Attinà

“…This approach addresses critical gaps in current practice while acknowledging resource limitations across diverse healthcare environments.…”
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Complexation with Alginate in Pumpkin Leaf Protein Solutions for the Encapsulation of Folic Acid: The Effect of Extraction Protocols by Predrag Petrović, Bojana Balanč, Jelena Mijalković, Tamara Đukić, Stefan Bošković, Verica Đorđević, Branko Bugarski, Viktor Nedović, Zorica Knežević-Jugović

“…This study aimed to assess pumpkin leaves as a protein source and determine the feasibility of these proteins to form complexes with alginate for the encapsulation of folic acid. …”
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Discovery of Genomic Targets and Therapeutic Candidates for Liver Cancer Using Single-Cell RNA Sequencing and Molecular Docking by Biplab Biswas, Masahiro Sugimoto, Md. Aminul Hoque

“…This study aims to uncover key genomic features, analyze their functional roles, and propose potential therapeutic drugs identified through molecular docking, utilizing single-cell RNA sequencing (scRNA-seq) data from liver cancer studies. …”
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Bioactives and Other Nutritional Components in the Jaggery Production Process by Nisha Pujari, Nirali Dedhia, Sanjay Mahajani, Narendra Shah, Amit Arora

“…Jaggery, a non-centrifugal sugar (NCS), is a naturally produced sweetener and a good source of minerals, essential vitamins and bioactives. …”
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Solar background radiation temperature calibration of a pure rotational Raman lidar by V. Jayaweera, R. J. Sica, G. Martucci, A. Haefele, A. Haefele

“…These measurements enable climatology studies and trend analyses to be performed. To detect long-term trends it is critical that the calibration of the system and the monitoring of its associated uncertainties are as reliable and continuous as possible. …”
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Intra action review of the cholera outbreak response in Kadoma city, Zimbabwe, 2024 by Clayton Munemo, Chido Zibanayi, Hamilton Gomba, Precious Banda, Sarah Tengawarima, Sikhanyisiwe Moyo, Daniel Chirundu

“…The working groups covered eight response pillars aligned to the five core functions of the Incident Management System (IMS). …”
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AN INFLUENCE OF SPONTANEOUS MICROFLORA OF FERMENTED HORSEMEAT PRODUCTS ON THE FORMATION OF BIOLOGICALLY ACTIVE PEPTIDES by I. M. Chernukha, I. N. Nikonov, N. G. Mashentseva, D. L. Klabukova, D. A. Afanasev, L. I. Kovalyov, L. А. Ilina

“…Therefore, in the studied product, good preservation of the main spectra of muscle proteins was observed, and the identified fractions, apparently, can be sources of new functional peptides. Not only quantitative but also qualitative changes were observed in the studied samples. …”
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