Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy by Ke C, Yu Y, Li J, Yu Y, Sun Y, Wang Y, Wang B, Lu Y, Tang M, Wang N, Chen Y

“…Then, downstream analyses were performed to detect protein interactions, gene function, cell type-specific expression and druggable information.Results: This study genetically predicted levels of 62 plasma proteins were associated with GD risk. …”
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Compact and Handheld SiPM-Based Gamma Camera for Radio-Guided Surgery and Medical Imaging by Fabio Acerbi, Aramis Raiola, Cyril Alispach, Hossein Arabi, Habib Zaidi, Alberto Gola, Domenico Della Volpe

“…We characterized the intrinsic position resolution (tested with pulsed light) as being ~200 µm, and the sensitivity and resolution when detecting gamma rays from Tc-99m source measured between 134 and 481 cps/MBq and as good as 1.4–1.9 mm, respectively.…”
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Identification of Soybean E1-E4 Gene Orthologs in the Guar Genome Using Comprehensive Transcriptome Assembly and Annotation by Luisa Criollo Delgado, Aleksei Zamalutdinov, Elena Potokina

“…Taub.), a well-known source of guar gum (food additive E 412). At high latitudes, e.g., in Russia, the main challenge for guar cultivation is the long photoperiod during summer, which delays flowering and maturation of guar plants. …”
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Impact of probiotic supplementation on serum levels of brain-derived neurotrophic factor: GRADE-based dose-response meta-analysis by Reza Hashemi, Mohammad M. Hussein M. Raouf, Tanya S. Salih, Marzieh Feyzpour, Maryam Eskandarioun, Najmeh Nezamabadipour, Hossein Gandomkar

“…Abstract Background Brain-derived neurotrophic factor (BDNF) is a key neurotrophin involved in neuroplasticity and cognitive function, with its dysregulation linked to neurodegenerative and psychiatric disorders. …”
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Vitamin C, Sugar Content, Color Intensity and Some Physicochemical Properties of Watermelon and Orange Peels by Selvican Gökçe, İsa Arslan Karakütük, Memnune Şengül

“…Therefore, orange peel can be used as a natural antioxidant and color source in the food, pharmaceutical, and cosmetic industries.…”
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Research note: Harnessing the potential of chicken blastodermal cells as a new frontier in poultry science and biotechnology – Establishment of embryonic stem cells and their diffe... by Małgorzata Duda, Patrycja Maciak, Grzegorz Tylko, Kamil Wartalski, Monika Trzcińska, Marek Romek, Marcin Samiec

“…Further research exploring the functional attributes of B-ESC-derived SC-LCs is required to elucidate their therapeutic potential in nerve reconstruction/repair.…”
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Targeted proteomics for absolute quantification of glucose transporter 1 in mammalian brain cells using liquid chromatography-mass spectrometry by Yash Mehta, Dhavalkumar Patel, Iqra Pervaiz, Ulrich Bickel, Abraham Jacob Al-Ahmad

“…Glucose represents a major source of energy for mammalian brains. Its uptake is tributary to a functional glucose transporter (GLUT1) expression at the blood-brain barrier (BBB). …”
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Effects of aspirin and omega-3 fatty acids on age-related macular degeneration in ASCEND-Eye: a randomised placebo-controlled trial in a population with diabetes by Praveen Patel, Rory Collins, Richard Peto, Mark Davies, Sanjiv Banerjee, David Simpson, John Anderson, Louise Bowman, Peter Scanlon, Amanda Adler, Andrew Farmer, Helen Cook, Laura Evans, Elizabeth Williamson, Louis Bolter, Jane Armitage, Peter Sandercock, Richard Gray, Nilesh Samani, Tasso Gazis, Richard Haynes, Arun Sachdev, Eric Wu, Elizabeth Wincott, Peter Sleight, Colin Baigent, Marion Mafham, Sarah Parish, Gavin Brown, Susan Hurley, Lynne Allsop, William Stevens, Theingi Aung, Allen Young, Emily Sammons, Georgina Buck, Imen Hammami, Jill Barton, Jonathan Bodansky, Roger McPherson, Lucy Fletcher, Murphy Kevin, Ryonfa Lee, Sandra Pickworth, Monica Willett, Michael Lay, Ola Murawska, Karen Melham, Jonathan Latham-Mollart, Anna Brewer, Mike Olson, Jude Kay, Alisha Griffiths, Helen Clayton, Philip Kirby, Mike Pennington, Dominic Clarke, Jenny Anslow, Alex Hallam, Jenny Witts, Sarah Egan, Alex Wharton, Amy Derbyshire, Katherine Hepplestone, Sujit Mithra, Su Oliver, Pauline Wiatrak-Olszewska, Kelly Alvey, Nick Gregory, Priyai Parkinson, Prema Maharajan, Rachel McFee, Donna Sowter, John Featonby, Richard Furnival, Helen Lipinski, Hazel Benjamin, Tanisha McAfee, Emma Payne Payne, Liz Still

“…Reports of AMD diagnoses were sourced from 6 monthly ASCEND follow-up questionnaires and a Visual Function Questionnaire.Participants 15 480 UK adults at least 40 years of age with diabetes but no evident cardiovascular disease.Interventions 100 mg aspirin daily versus placebo and, separately, 1 g omega-3 FAs daily versus placebo.Main outcome measure The first post-randomisation reports of AMD.Results During 7.4 years of follow-up, 122 (1.6%) participants randomised to aspirin were reported as having AMD, compared with 138 (1.8%) randomised to placebo (rate ratio 0.88; 95% CI 0.69 to 1.12; p=0.31). …”
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Repair of aircraft engine parts made of heat-resistant nickel alloys using additive plasma technologies by Konstantin Balushok, Sergey Chigileychik

“…No wear of the labyrinth ridges or cracks was detected. The functionality of the restored disk has been confirmed. …”
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Preliminary exploration of mRNA, lncRNA, and miRNA expressions in the bovine jejunum unveils novel aspects of Mycobacterium avium subspecies paratuberculosis infections by Yahui Gao, Jie Cao, Bo Han, Dongxiao Sun

“…This study provided a valuable resource for understanding the molecular basis of JD, potentially contributing to the genetic improvement of JD resistance in dairy cattle.…”
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CGREF1 modulates osteosarcoma proliferation by regulating the cell cycle through the Wnt/β-catenin signaling pathway by Zicheng Wei, Kezhou Xia, Wenda Liu, Xinghan Huang, Zhun Wei, Weichun Guo

“…Methods Tumor Immune Estimation Resource (TIMER), The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases were utilized for bioinformatics analysis. …”
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The cnf1 gene is associated with an expanding Escherichia coli ST131 H30Rx/C2 subclade and confers a competitive advantage for gut colonization by Landry L. Tsoumtsa Meda, Luce Landraud, Serena Petracchini, Stéphane Descorps-Declere, Emeline Perthame, Marie-Anne Nahori, Laura Ramirez Finn, Molly A. Ingersoll, Rafael Patiño-Navarrete, Philippe Glaser, Richard Bonnet, Olivier Dussurget, Erick Denamur, Amel Mettouchi, Emmanuel Lemichez

“…In addition, functional analysis of the cnf1-positive clinical strain EC131GY ST131-H30Rx/C2 and a cnf1-deleted isogenic strain showed no detectable impact of the CNF1 gene on bacterial fitness and inflammation during the acute phase of bladder monoinfection. …”
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Statistics on the Industry Structure of the Russian Economy and its Optimization Model by O. V. Morozov, M. A. Vasiliev

“…Optimization of the scale of industries is the formation of structural conditions for a more efficient functioning of the Russian economy; it can be recognized as a macroeconomic condition and a strategic reserve for the economic growth.…”
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Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov... by Leonie Seemann, Susanne Kersten, Susanne Bühler, Fabian Billenkamp, Ulrich Meyer, Christian Visscher, Korinna Huber, Erika Most, Klaus Eder, Sven Dänicke, Jana Frahm

“…A contrasting pattern was detected for the gene expression of cytochrome c oxidase subunit 4I1 (COX4I1), with stable levels in CON and a downregulation in CAR due to LPS injection. …”
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High prevalence of fecal carriage of extended-spectrum beta-lactamase producing Enterobacterales among patients with urinary tract infections in rural Tanzania by Magreth Erick Macha, Magreth Erick Macha, Magreth Erick Macha, Weihong Qi, Salome N. Seiffert, Anja Bösch, Philipp Kohler, Honorathy Msami Urassa, Sabine Haller, Erin West, Maja Weisser Rohacek, Maja Weisser Rohacek, Maja Weisser Rohacek, Baharak Babouee Flury, Baharak Babouee Flury, Baharak Babouee Flury, Baharak Babouee Flury

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Klebsiella pneumoniae under xylose pressure: the growth adaptation, antimicrobial susceptibility, global proteomics analysis and role of XylA and XylB proteins by Ruolan Yi, Jiaoyang Zheng, Zhichao Xu, Jiayan Wu, Fangfang Liu, Jinxin Zheng, Duoyun Li, Shiqing Han, Zhijian Yu

“…Additionally, while the growth adaptation of K2044−8Xyl−60G under xylose pressure was confirmed, no amino acid mutations were detected in the functional proteins of this xylose-induced isolate, suggesting that persistent xylose pressure does not cause nonsense mutations in the bacterial genome. …”
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Pulmonary complications in children and adolescents after allogeneic hematopoietic stem cell transplantation by A. S. Frolova, A. G. Volkova, O. V. Paina, P. V. Kozhokar, K. A. Ekushov, Zh. Z. Rakhmanova, L. A. Cvetkova, E. D. Dobrovolskaya, B. I. Smirnov, E. A. Kulagin, T. A. Bykova, E. V. Semenova, L. S. Zubarovskaya

“…All the patients underwent chest computed tomography (CT). When detecting CT changes, we performed fibrobronchoscopy (FBS) with microbiological examination of bronchoalveolar lavage (BAL).Results. …”
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Biomechanical Changes to the Ankle After Zadek Osteotomy by Nicholas Bellas MD, Raghunandan Nayak BS, Mehreen Pasha BS, Megan R. Wolf MD, Elifho Obopilwe MS, Thomas McDonald MD, Lauren E. Geaney MD

“…Category: Hindfoot; Sports Introduction/Purpose: Insertional Achilles tendinopathy is a common source of heel pain in active adults and athletes. …”
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The amino acid composition of Polygonum hydropiper L. and Polygonum persicaria L. herbs of Ukrainian flora by I. A. Lukina, O. V. Mazulin, H. P. Smoilovska, H. V. Mazulin, I. N. Shevchenko

“…The received results testify the promising use of the plant material and will be considered in the future work for the more in-depth study of the selected objects as a source of natural bioactive substances.…”
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Acoustic Features for Identifying Suicide Risk in Crisis Hotline Callers: Machine Learning Approach by Zhengyuan Su, Huadong Jiang, Ying Yang, Xiangqing Hou, Yanli Su, Li Yang

“…Basic acoustic features (eg, Mel Frequency Cepstral Coefficients, formant frequencies, jitter, shimmer) and high-level statistical function (HSF) features (using OpenSMILE [Open-Source Speech and Music Interpretation by Large-Space Extraction] with the ComParE 2016 configuration) were extracted. …”
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