Tumor-specific CD8+ T cells from the bone marrow resist exhaustion and exhibit increased persistence in tumor-bearing hosts as compared with tumor-infiltrating lymphocytes by Ivan Borrello, Amy Thomas, Luca Biavati, Robert Leone, Elizabeth M Zawidzka, Claudio Zanettini, Luigi Marchionni

“…Importantly, in a competitive transfer experiment, BM T cells infiltrated the tumor more efficiently than TILs, displayed a higher polyfunctionality with interleukin-2, interferon-γ, tumor necrosis factor-α production and showed greater persistence compared with TILs.Conclusions T cells from the BM appear superior to TILs as a source of cells for cellular therapy. They possess a memory-enriched phenotype and exhibit improved effector function, greater persistence within a tumor-bearing host, and the capacity for increased tumor infiltration. …”
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Feeding black soldier fly (Hermetia illucens) larvae with mushrooms and then exposing them to UVB produces larvae extremely rich in vitamins D2 and D3 by Lisa Morand-Laffargue, Florence Charles, Charlotte Sabran, Patrick Borel

“…Black soldier fly larvae (BSFL) are a sustainable source of protein for feed but they can also be a sustainable source of some phytochemicals due to their ability to bioaccumulate them. …”
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Protective role of extracellular vesicles against oxidative DNA damage by Jordi Ribas-Maynou, Ana Parra, Pablo Martínez-Díaz, Camila Peres Rubio, Xiomara Lucas, Marc Yeste, Jordi Roca, Isabel Barranco

“…Abstract Background Oxidative stress, a source of genotoxic damage, is often the underlying mechanism in many functional cell disorders. …”
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Extracting Realistic Pedestrian, Cycling, and Driving Street Networks from OpenStreetMap by J. P. Duque, M. A. Brovelli

“…An algorithm was designed to detect these cases based on the geometry of the street segments. …”
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Exploration of Predicted Nitrogen-Containing Natural Products from Northern Canadian Bark Beetle-Associated Bacteria by Nirasha Atapattu, Nicolas Justus, Hariniha Selvarajan, Mitzchilouise Baylosis, Marc Schieven, Kalindi D. Morgan

“…Nitrogen-15 NMR spectroscopy was employed to detect nitrogen-containing functional groups in crude extracts, revealing distinct signals for amides, amines, and nitrogen heterocycles. …”
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IDENTIFICATION OF ELECTROMAGNETIC ULTRA LOW FREQUENCY (ULF) SIGNAL ANOMALIES AS PRECURSORS OF A MAGNITUDE 5 EARTHQUAKE IN THE SULAWESI REGION by Delfira Anggraini, Ratni Sirait, Lailatul Husna Lubis, Christofel Haposan Great Sibuea

“…The anomaly source azimuth direction was also determined.…”
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Regional and strain-level prevalence of nitrogen-fixing Bradyrhizobium with potential N2O reduction in South Korea by Jaeyoung Ro, Hor-Gil Hur, Sujin Lee

“…Abstract Agricultural practices are the largest anthropogenic source of nitrous oxide (N2O), a potent greenhouse gas contributing to global climate change. …”
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Repair-mediated duplication by capture of proximal chromosomal DNA has shaped vertebrate genome evolution. by John K Pace, Shurjo K Sen, Mark A Batzer, Cédric Feschotte

“…These events are thought to be a source of genomic instability and human diseases, but it is unclear whether they have contributed significantly to genome evolution. …”
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Devicology: Expanding fieldwork possibilities for architectural observations in inhabited interiors by Tatiana Knoroz

“…These visually chaotic yet surprisingly functional structures are the only tool of the current dwellers to negotiate with the restricting standard apartment plans that were originally designed for a very different sector of the Japanese population. …”
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The Role of High-mass Stellar Binaries in the Formation of High-mass Black Holes in Dense Star Clusters by Ambreesh Khurana, Sourav Chatterjee

“…We study the differences in the demographics of BH–BH mergers and their implications for LIGO–Virgo–Kagra detections as a function of ${f}_{{\rm{b}},15}^{{\prime} }$ .…”
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Sodium formate induces development-dependent intestinal epithelial injury via necroptosis and apoptosis by Jingjing Wei, Yuan Tian, Meiqi Guan, Jinshu Wei, Yong Ji, Guozhong Tao, Karl G. Sylvester

“…Mice were sacrificed after 24 h of feces collection, and the blood and small intestinal tissues were collected to detect the pathological damage of intestinal tissue, intestinal permeability, oxidative stress indicators including SOD, HO-1, MDA, and 4-HNE, inflammatory cytokines including IL-1β, TNF-α and IL-6, mitochondrial function such as ATP and PGC-1α in mice intestinal tissue, indicators of the cell death modes including necroptosis-related protein RIPK1 and p-MLKL, and apoptosis- related protein cleaved-caspase-3 and p-AKT (S473).Results NaF treatment significantly damaged intestinal epithelial tissue and barrier function, caused mitochondrial dysfunction, manifesting as decreased ATP and PGC-1α levels, increased lipid peroxidation products MDA and 4-HNE, depleted antioxidant enzyme SOD, and upregulated the expression of HO-1. …”
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Genome Mining of Terpene Synthases from Fourteen <i>Streptomyces</i> Strains by Yuanyuan Li, Xi Xiang, Zhiyuan Ren, Rui Wang, Minghui Xie, Gen Li, Xiaohui Yan, Zhilong Zhao, Zixin Deng, Min Xu, Anwei Hou

“…A total of forty-eight TPSs were identified and categorized through phylogenetic analysis, and five representative TPSs distantly related to known TPSs were selected for functional investigation. Biochemical assays revealed that TAC28_6116 is a sesquiterpene synthase producing thujopsan-2β-ol (<b>1</b>) and thujopsene (<b>2</b>), marking the first report of thujopsan-2β-ol production from a bacterial source. …”
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Evaluation of Cloud Masking Methods using Sentinel-2 Satellite Images on Google Earth Engine: A Case Study in Vietnam by Le Minh Hang, Bui Xuan Hung, Nguyen Thi Thu Nga, Mai Phuong Pham, Nguyen Quoc Khanh

“…These include the Fmask (Function of mask) method, the Fmask CDI (Cloud Displacement Index) method, and the Fmask CSP (Cloud Score Plus) method. …”
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Biomimetic Hydrodynamic Sensor with Whisker Array Architecture and Multidirectional Perception Ability by Huangzhe Dai, Chengqian Zhang, Hao Hu, Zhezai Hu, Haonan Sun, Kan Liu, Tiefeng Li, Jianzhong Fu, Peng Zhao, Huayong Yang

“…The whisker sensor is capable of detecting a variety of hydrodynamic information, including the velocity (RMSE < 0.061 m s−1) and direction of the steady flow field, the frequency (error < 0.05 Hz) of the dynamic vortex wake, and the orientation (error < 7°) of the vortex wake source, demonstrating its extensive potential for underwater environmental perception and communication, especially in deep sea conditions.…”
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Joint Survey Processing. III. Compact Oddballs in the COSMOS Field—Little Red Dots and Transients by Yu-Heng Lin, Andreas L. Faisst, Ranga-Ram Chary, Anton M. Koekemoer, Joseph Masiero, Daniel Masters, Vihang Mehta, Harry I. Teplitz, Gregory L. Walth, John R. Weaver

“…We draw the upper limit of the AGN luminosity function Φ = 1.1 × 10 ^−7 Mpc ^3 mag ^−1 for M _UV = −21 at redshift of 6. …”
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Multiwavelength Variability Analysis of the Blazar PKS 0727-11: An ~ 168 day Quasiperiodic Oscillation in the γ-Ray by Yuncai Shen, Tingfeng Yi, Vinit Dhiman, Lisheng Mao, Liang Dong

“…It is the first time that periodic variations have been detected in this source, and further supported by other methods: weighted wavelet z -transform, phase dispersion minimization, REDFIT, autoregressive integrated moving average model, and structure function analysis. …”
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Current status of transcriptome sequencing technology in ruminants by Cui JiaYu, Song Lili, Wang Dawei, Liu ZhiLin, Zhang Xin, Jia Zelin, Zhang Yuhang, Xiong Huisheng, Wang Xueli

“…During the lactation stage of ruminants, transcriptome sequencing is used to screen for differentially expressed genes in blood tissue, which can identify candidate functional genes for milk production traits. Transcriptome sequencing can detect genes with low expression levels, identify new gene transcripts and alternative splicing events, detect and analyze the biological regulatory mechanisms of the body, reveal differences in gene expression levels during breeding, and reveal the interaction between hosts and pathogens. …”
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User Communities — Drivers for Open Innovation by Gunnar Prause, Thomas Thurner

“…Users best judge what will lead to commercial success, and they have long been recognized as a valuable source of knowledge to harvest for future innovation. …”
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Agarwood leaf ethanol extract provides neuroprotective properties and promotes cholinergic differentiation of HT22 hippocampal neurons by Kishoree K. Kumaree, James M. Brimson, Kanika Verma, Siriporn Chuchawankul, Tewin Tencomnao, Anchalee Prasansuklab

“…Abstract Neurodegenerative diseases, characterized by the loss or damage of neurons, represent a growing global health concern. Plants are a rich source of naturally occurring compounds with immense therapeutic potential. …”
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Assessing Cerebrovascular Reactivity in Carotid Steno-Occlusive Disease Using MRI BOLD and ASL Techniques by Renata F. Leoni, Kelley C. Mazzetto-Betti, Afonso C. Silva, Antonio C. dos Santos, Draulio B. de Araujo, João P. Leite, Octavio M. Pontes-Neto

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