CoreTIA: a modular, statistically robust transduction inhibition assay for AAV neutralization by Beatrix Kovács, Beatrix Kovács, Beatrix Kovács, Fanni Somogyi, Fanni Somogyi, Viktória Szabó, Zoltán Zsolt Nagy, István Hernádi, Ferenc Mátyás, Wim Vanduffel, Zsuzsanna Szemlaky, Balázs Rózsa, Balázs Rózsa, István Ulbert, István Ulbert, István Ulbert, István Ulbert, Dániel Hillier, Dániel Hillier, Dániel Hillier

Get full text

Development of a Novel KCNN4-Related ceRNA Network and Prognostic Model for Renal Clear Cell Carcinoma by Hengtao Bu, Qiang Song, Jiexiu Zhang, Yuang Wei, Bianjiang Liu

“…Finally, quantitative real-time polymerase chain reaction and western blot were conducted for KCNN4 expression detection in cell lines and clinical samples. Small interfering RNA was employed to knock down KCNN4, and corresponding functional experiments were conducted on ccRCC cells as well. …”
Get full text

The impact of early massive galaxy formation on the cosmic microwave background by Eda Gjergo, Pavel Kroupa

“…A previously overlooked foreground component is the formation of massive early-type galaxies (ETGs), which can no longer be ignored, particularly in light of JWST's detection of massive, evolved systems at extreme redshifts (z>13). …”
Get full text

Predictive Capabilities and Limitations of Stream Interaction Region Observations at Different Solar Longitudes by R. C. Allen, G. C. Ho, L. K. Jian, G. M. Mason, S. K. Vines, D. Lario

“…Through comparing 10 years of SIRs/CIRs observed at L1 and at STEREO, we have investigated the probability of sequentially detecting SIRs/CIRs at two locations as a function of the difference in heliospheric longitude and latitudinal separation between the two spacecraft. …”
Get full text

Bacteriological Quality Assessment of Water Sold in Plastic Jerry cans within Katsina Metropolis, Katsina State, Nigeria. by Galadanchi Fatima A., Shamsuddeen Umar, Yusuf Buhari, Abubakar Abdulazeez, Salisu Mansur Dabai

“…It is the most abundant molecule in living cells, essential for the proper functioning of cells. It is one of the cheap vehicles that transport gastro-intestinal diseases. …”
Get full text

Legality of bringing to administrative responsibility for an offense under Art. 130 Code of Ukraine on Administrative Offenses: retrospective analysis by K. O. Chyshko

“…It was stated that the clarification provided in this regard by the Committee on Law Enforcement of the Verkhovna Rada of Ukraine is neither a source of law nor a normative legal act and is not binding, but instead serves a recommendatory function, therefore, the involvement of persons for committing a specific criminal offense under the procedure of proceedings on administrative offenses has no legal grounds.…”
Get full text

New Insights on Quality, Safety, Nutritional, and Nutraceutical Properties of Honeydew Honeys from Italy by Andrea Mara, Federica Mainente, Vasiliki Soursou, Yolanda Picó, Iratxe Perales, Asma Ghorab, Gavino Sanna, Isabel Borrás-Linares, Gianni Zoccatelli, Marco Ciulu

“…This contribution aims to provide a comprehensive characterization of the physico-chemical, palynological, functional, and food safety properties of a large sampling of honeydew honeys collected throughout Italy. …”
Get full text

Characteristics of Land Use Change and Evaluation of Ecological Sensitivity in Chongqing by XIE Xianjian, GOU Qiantao, WU Han

Get full text

Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons by Irika R. Sinha, Parker S. Sandal, Holly Spence, Grace D. Burns, Aswathy Peethambaran Mallika, Fatemeh Abbasinejad, Katherine E. Irwin, Anna Lourdes F. Cruz, Vania Wang, Shaelyn R. Marx, Josué Llamas Rodríguez, Ben Langmead, Jenna M. Gregory, Philip C. Wong, Jonathan P. Ling

“…We previously found that TDP-43 loss-of-function leads to transcriptome-wide inclusion of deleterious cryptic exons, a signature detected in presymptomatic biofluids and postmortem ALS-FTD brain tissue, but the upstream mechanisms that lead to TDP-43 dysregulation remain unclear. …”
Get full text

High-Sensitivity Determination of K, Ca, Na, and Mg in Salt Mines Samples by Atomic Emission Spectrometry with a Miniaturized Liquid Cathode Glow Discharge by Jie Yu, Zhichao Zhang, Quanfang Lu, Duixiong Sun, Shuwen Zhu, Xiaomin Zhang, Xing Wang, Wu Yang

Get full text

Identification of miRnas with possible prognostic roles for HAM/TSP by Daniela Raguer Valadão de Souza, Rodrigo Pessôa, Youko Nukui, Juliana Pereira, Rosa Nascimento Marcusso, Augusto César Penalva de Oliveira, Jorge Casseb, Alberto José da Silva Duarte, Patricia Bianca Clissa, Sabri Saeed Sanabani

“…The seven most deregulated miRs target genes have been associated with a variety of biological processes and molecular functions. The reactome pathways relevant to our findings provide a rich source of data and offer the opportunity to better understand sRNA regulation and function in HTLV-1 pathophysiology. …”
Get full text

Characterize the Complete Mitogenome of Semiaquilegia guangxiensis and Assess the Efficiency of the Mitochondrial Genes in Ranunculales Phylogeny by Zheng‐Juan Zhu, Xin‐Mei Qin, Peng‐Wei Li, Yong‐Bin Lu, Xiao‐Yuan Mo, Yuan Fang, Qiang Zhang

“…Moreover, a large number of repetitive mitogenome sequences and chloroplast‐sourced sequences transferred to the mitogenome were detected. …”
Get full text

Farmers’ knowledge and perception of finger millet blast disease and its control practices in western Kenya by Wilton Mbinda, Agnes Kavoo, Fredah Maina, Margaret Odeph, Cecilia Mweu, Naomi Nzilani, Mathew Ngugi

“…Abstract Background Finger millet blast disease, caused by Pyricularia oryzae, is a serious constrain of finger millet production which is threatening global food security especially to the resource poor smallholder farmers in arid and semi-arid regions. …”
Get full text

Wind Turbine Static Errors Related to Yaw, Pitch or Anemometer Apparatus: Guidelines for the Diagnosis and Related Performance Assessment by Davide Astolfi, Silvia Iuliano, Antony Vasile, Marco Pasetti, Salvatore Dello Iacono, Alfredo Vaccaro

“…Nevertheless, methods based on additional information sources (like further sensors or meteorological data) are also discussed. …”
Get full text

A SPectroscopic Survey of Biased Halos in the Reionization Era (ASPIRE): Spectroscopically Complete Census of Obscured Cosmic Star Formation Rate Density at z = 4–6 by Fengwu Sun, Feige Wang, Jinyi Yang, Jaclyn B. Champagne, Roberto Decarli, Xiaohui Fan, Eduardo Bañados, Zheng Cai, Luis Colina, Eiichi Egami, Joseph F. Hennawi, Xiangyu Jin, Hyunsung D. Jun, Yana Khusanova, Mingyu Li, Zihao Li, Xiaojing Lin, Weizhe Liu, Romain A. Meyer, Maria A. Pudoka, George H. Rieke, Yue Shen, Wei Leong Tee, Bram Venemans, Fabian Walter, Yunjing Wu, Huanian Zhang, Siwei Zou

“…We identify eight DSFGs in seven fields at z = 4–6 through the detection of H α or [O  iii ] λ 5008 lines, including fainter lines such as H β , [O  iii ] λ 4960, [N  ii ] λ 6585, and [S  ii ] λλ 6718,6733 for six sources. …”
Get full text

In Vitro Inhibition of Enzymes and Antioxidant and Chemical Fingerprinting Characteristics of <i>Azara serrata</i> Ruiz & Pav. Fruits, an Endemic Plant of the Valdivian Forest of C... by Philipp Hopfstock, Javier Romero-Parra, Peter Winterhalter, Recep Gök, Mario Simirgiotis

“…The results show that these neglected endemic small berries can be a source of healthy phytochemicals. These Chilean berries can be used as functional food and their extracts are candidates for use as functional ingredients in naturally healthy products.…”
Get full text

Study on the effect of environmental humidity on the thermal decomposition characteristics of PVC outer sheath of high-voltage cables by Zhaoguo Wu, Qian Wang, Qianbo Xiao, Ke Wu, Qianglin Fu, Huixian Huang, Hong Xiang, Zhengqin Cao

“…Thermal decomposition experiments were conducted across ten humidity gradients, ranging from 10 to 100%, using a specially designed experimental platform that included heating, temperature and humidity control, and gas detection. Set a heat source of 200℃ to simulate the early fault state of high-voltage cables before a fire occurs. …”
Get full text

Genome-Wide Ultrabithorax Binding Analysis Reveals Highly Targeted Genomic Loci at Developmental Regulators and a Potential Connection to Polycomb-Mediated Regulation. by Daria Shlyueva, Antonio C A Meireles-Filho, Michaela Pagani, Alexander Stark

“…Furthermore, Ubx binding was detected at known Polycomb response elements (PREs) and was associated with significant enrichments of Pc and Pho ChIP signals in contrast to binding sites of other developmental TFs. …”
Get full text

Incorporating Non-Coding Annotations into Rare Variant Analysis. by Tom G Richardson, Colin Campbell, Nicholas J Timpson, Tom R Gaunt

“…<h4>Methods & results</h4>We conducted a candidate gene analysis using the UK10K sequence and lipids data, filtering according to functional annotations using the resource CADD (Combined Annotation-Dependent Depletion) and contrasting results with 'nonsynonymous' and 'loss of function' consequence analyses. …”
Get full text

An openEHR based infection control system to support monitoring of nosocomial bacterial clusters and contacts by Pascal Biermann, Claas Baier, Ann Christin Vietor, Benedikt Zacher, Tom Baumgartl, Tatiana von Landesberger, Michael Behnke, Michael Storck, Markus Petzold, Martin Kaase, HiGHmed lnfection Control Study Group, Dirk Schlüter, Michael Marschollek, Simone Scheithauer, Antje Wulff

“…Digital, routine data-driven solutions are promising, but often proprietary, non-interoperable, or limited in functional scope. The open-source Smart Infection Control System (SmICS) offers automatic calculations and interactive views on patients' movement and lab data, epidemic curves, contact networks, complemented by temporal-spatial visualizations. …”
Get full text