Targeting GJB4 to inhibit tumor growth and induce ferroptosis in pancreatic cancer by Xiangru Zheng, Wenjun Li, Xiaoli Li, Qianyi Yao, Luquan Zheng, Rongrong Fan, Ping Bie

“…Bioinformatics analysis was conducted to explore the function of GJB4 in PC cells. Changes in ferroptosis in PC cells following GJB4 downregulation were detected by immunofluorescence staining, transmission electron microscopy, and western blotting.ResultsGJB4 expression was found to be upregulated in PC tissues and positively correlated with patient survival. …”
Get full text

Genomic insights into population dynamics and adaptive strategies of the endangered dipterocarp, Hopea chinensis by Wei-Min Xiang, Yu-Ting Jiang, Jie Zou, Yan Deng, Kai Jiang, Kai-Jian Zhang, Xin-Yu Zhou, Kai-Xi Quan, Zi-Wen Han, Wei-Chao Liu, Liang Tang, Yuan-Yuan Li, Simon T. Segar, Yuan-Ye Zhang, Xing-Hua Hu, Rong Wang, Xiao-Yong Chen

Get full text

Gene Network Biological Validity Based on Gene-Gene Interaction Relevance by Francisco Gómez-Vela, Norberto Díaz-Díaz

“…Finally, the ability of GeneNetVal to detect biological functionality of the network is shown.…”
Get full text

Advanced Suspension Techniques in Interferometric Gravitational Wave Detectors: An Overview by Vishnu G. Nair

“…This isolation is crucial for enabling the detectors to function efficiently at low frequencies, which directly impacts their capacity to detect distant events from the universe’s past. …”
Get full text

MergeBot: A platform of semi-structured merge conflict resolution for C/C++ code by Hua He, Xiaofan Liu, Lei Xu, Guanghui Mei, Jifeng Xuan

“…In software version control systems, like Git, merge conflicts typically arise when multiple developers edit the same segment of a source file from different branches. Detecting merge conflicts can be automated; however, resolving merge conflicts is tedious and demanding. …”
Get full text

Native bacteria from a Mediterranean greenhouse associated to soil health and suppressiveness by Jose Ignacio Marín-Guirao, Miguel de Cara-García

“…Among the 52 ecological pathways detected via FAPROTAX database, nitrogen-related functions showed higher presence at the end of the cropping seasons. …”
Get full text

Kajian Farmakoinformatika Senyawa Alkaloid Anggur Laut (Caulerpa racemose) Sebagai Inhibitor Collagenase Dalam Mekanisme Antiaging by Dewi Ratih Tirto Sari, M.Eko Pranoto, Siti Zamilatul Azkiyah

“…Sea grapes also well known as functional food source from marine, contains high protein, fibers and secondari metabolites. …”
Get full text

Lipoprotein N-terminal modification in Bacillus: a new paradigm for extracellular acetylation and species-dependent Toll-like receptor 2 immunomodulation by Gloria Komazin, Rachel M. Wigmore, Aditi M. Ranade, Amena A. Rizk, John H. Gardiner, Timothy C. Meredith

“…While Ac-LP biosynthetic pathway genes appear to be universally conserved in all Bacillus spp., those associated with pathogenic lineages have often lost function. In B. anthracis strains, LhaT has been inactivated by insertion of poly-tyrosine runs of variable length that favors chemotype conversion to lyso-LP and evasion of TLR2 detection. …”
Get full text

Identification of Intracranial Germ Cell Tumors Based on Facial Photos: Exploratory Study on the Use of Deep Learning for Software Development by Yanong Li, Yixuan He, Yawei Liu, Bingchen Wang, Bo Li, Xiaoguang Qiu

“…Due to their insidious onset and impact on critical functional areas of the brain, these tumors often result in irreversible abnormalities in growth and development, as well as cognitive and motor impairments in affected children. …”
Get full text

Reconstruction of the object inhomogeneity parameters from near-field measurements in microwave tomography problem using neural networks by A.V. Medvedev, M.Yu. Medvedik

“…The field is induced by a point source located outside the body. Materials and methods. …”

Visible Triple-Wavelength Switchable Emission Generated in Passively Q-Switched Nd:YVO₄ Self-Raman Laser by Songtao Li, Shengxi Zheng, Bowen Zheng, Yong Wei, Yongchang Zhang, Yanmin Duan, Haiyong Zhu

Get full text

Green Recovery and Identification of Antioxidant and Enzyme Inhibitor Molecules from Pisco Grape Pomace by Targeted Effects Analysis Using Thin-Layer Chromatography, Bioassay, and... by Jacqueline Poblete, Joaquín Fernández-Martínez, Mario Aranda, Issis Quispe-Fuentes

“…Bioactive molecules were detected and identified applying directed effect analysis on planar chromatography coupled to mass spectrometry. …”
Get full text

Bearing Small Sample Fault Diagnosis based on Data Generation and Transfer Learning by Dinghui Wu, Qin Fang, Chuyi Wu

“…First， the source dataset is trained on the training network to obtain the source model， and then a small amount of drive-end data is used as the target dataset to fine-tuning to obtain the target model. …”
Get full text

Unlocking the potential of circulating small extracellular vesicles in neurodegenerative disease through targeted biomarkers and advancements in biosensing by Saqer Al Abdullah, Ivy Cocklereece, Kristen Dellinger

“…Neurodegenerative diseases (NDDs) gradually affect neurons impacting both their function and structure, and they afflict millions worldwide. …”
Get full text

Growth Toxic Effects of Metal Nanoparticles on Bacillus subtilis and Vibrio parahaemolyticus by Shiyu CHEN, Bin XIA, Lin ZHU, Shuang LI, Qiufen LI, Xuemei SUN, Wei DAI

“…Based on the ecological roles and functions of these two bacteria in marine microbial communities, this study used B. subtilis and V. parahaemolyticus isolated from Bohai Bay as test organisms. …”
Get full text

Spectral domain optical coherence tomography: a better OCT imaging strategy by Zahid Yaqoob, Jigang Wu, Changhuei Yang

“…There are two approaches to SDOCT—one that uses a broadband source and a spectrometer to measure the interference pattern as a function of wavelength and the other that utilizes a narrowband tunable laser that is swept linearly in k ∼ 1/λ space during spectral fringe data acquisition. …”
Get full text

A quantum inspired machine learning approach for multimodal Parkinson’s disease screening by Diya Vatsavai, Anya Iyer, Ashwin A. Nair

“…As disease progression impairs speech, memory, and motor functions over time, early diagnosis is crucial for preserving patients’ quality of life. …”
Get full text

On Power-Off Temperature Attacks Potential Against Security Sensors by Maryam Esmaeilian, Vincent Beroulle, David Hély

“…Although numerous security sensors and attack detectors have been proposed in the literature to detect different sources of FIAs, it is crucial to ensure that these mechanisms themselves have not been tampered. …”
Get full text

Carbon-Based Nanoadsorbents for the Removal of Emerging Pollutants by M. Venkata Ratnam, P. Akilamudhan, K. Senthil Kumar, S. Narasimha Reddy, K. Nagamalleswara Rao, Feroz Shaik, D. M. Reddy Prasad

“…Emerging contaminants (ECs) are substances that have been detected in water but have not been thoroughly tested or regulated. …”
Get full text

Ultra-high-energy γ-ray emission associated with the tail of a bow-shock pulsar wind nebula

“…The source energy spectrum extended up to 300 TeV, which was well fitted by a log-parabola function with N0 = (1.93 ± 0.23) × 10−16 TeV−1 cm−2 s−1, α = 2.14 ± 0.27, and β = 1.20 ± 0.41 at E0 = 30 TeV. …”
Get full text