Validation of the inadequate delivery of oxygen index in an adult cardiovascular intensive care unitCentral MessagePerspective by Heather Holman, BS, Dimitar Baronov, PhD, Jeff McMurray, MD, Arman Kilic, MD, Marc Katz, MD, Sanford Zeigler, MD

“…Conclusions: The IDO2 index is capable of detecting SvO2 ≤50% with good discriminatory function in non-MCS CVICU patients in a variety of monitoring situations. …”
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Current trends in neurocritical care: a comprehensive review by Vinothini Murugaiyan, Kingston Samraj Kirubakaran Jebaraj, Srinivas Kalaiselvan

“…Continuous neuromonitoring using tools like electroencephalogram and intracranial pressure monitoring offers real-time data on brain function, aiding in the early detection of complications. …”
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Metaproteomics in the One Health framework for unraveling microbial effectors in microbiomes by Robert Heyer, Maximilian Wolf, Dirk Benndorf, Sergio Uzzau, Jana Seifert, Lucia Grenga, Martin Pabst, Heike Schmitt, Bart Mesuere, Tim Van Den Bossche, Sven-Bastiaan Haange, Nico Jehmlich, Mariagrazia Di Luca, Manuel Ferrer, Sergio Serrano-Villar, Jean Armengaud, Helge B. Bode, Patrick Hellwig, Catherine Robbe Masselot, Renaud Léonard, Paul Wilmes

“…Metaproteomics offers a novel methodological framework as it provides insights into microbial dynamics by quantifying microbial biomass composition, metabolic functions, and detecting effectors like viruses, antimicrobial resistance proteins, and non-ribosomal peptides. …”
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The Role of Rivaroxaban in a Comprehensive Protection Strategy for Patients with Atrial Fibrillation by I. A. Zolotovskaya, V. D. Sabanova, I. L. Davydkin

“…Atrial fibrillation is often asymptomatic and timely detection of these patients can be one of the most important tasks in the complex of measures aimed at protecting patients from stroke. …”
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Research on Buckwheat Weed Recognition in Multispectral UAV Images Based on MSU-Net by Jinlong Wu, Xin Wu, Ronghui Miao

“…The neuron death caused by the original ReLU activation function may lead to misidentification, so it was replaced by the Swish function to improve the adaptability to complex inputs. …”
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Fluxgate Magnetometers Based on New Physical Principles by Ivan V. Bryakin, Igor V. Bochkarev, Vadim R. Khramshin, Vadim R. Gasiyarov, Ivan N. Erdakov

“…The authors considered a generalized flow of the physical processes in the FM to obtain a detailed representation of the operating functions of the FM. The presented experimental results for the proposed FM in the field meter mode confirm its operating parameters (±40 μT—measurement range, 0.5 nT—detection threshold). …”
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Wastewater metagenomics in Africa: Opportunities and challenges. by Stephen Kanyerezi, Fatma Zahra Guerfali, Abbas Abel Anzaku, Oluwasegun Adesina Babaleye, Tracey Calvert-Joshua, Julien Alban Nguinkal, Oluwaseun Paul Amoo, Chiraz Atri, Waqasuddin Khan, Iqra Saleh, M Imran Nisar, Arthur Shem Kasambula, Koketso Morapedi, Gerald Mboowa

“…The advent of metagenomics has dramatically expanded our understanding of microbial communities, particularly through the study of wastewater, which serves as a rich source of microbial data. In Africa, wastewater metagenomics presents unparalleled opportunities for public health monitoring, antimicrobial resistance (AMR) tracking, and the discovery of new microbial species and functions. …”
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A new fluorescent probe based on BODIPY for testing NO2 released from propellants by Ying-cui Cui, De-bin Xia, Zhong-yu Cui, Yu-jing Li, Jian Zhang, Ping Wang, Ting Guo, Kai-feng Lin, Yu-lin Yang

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A methodology for quantitatively managing the bug fixing process using Mahalanobis Taguchi system by Boby John, R. S. Kadadevarmath

“…The controlling of bug fixing process during the system testing phase of software development life cycle is very important for fixing all the detected bugs within the scheduled time. The presence of open bugs often delays the release of the software or result in releasing the software with compromised functionalities. …”
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Establishing a long-term predictive model for aggressive behavior in schizophrenia: a 21-year longitudinal study in rural China by Hui Jin, Hui Jin, Cong Wang, Cong Wang, Yi-Yue Yang, Yi-Yue Yang, Lie Zhou, Lie Zhou, Yun Xiao, Yun Xiao, Yang Wen, Yang Wen, Jawad Ahmad, Jawad Ahmad, Yun-Fei Mu, Yun-Fei Mu, Jia Cai, Ming Li, Wei Luo, Xiao-Fei Zhou, Jian-Jun Luo, Bo Liu, Eric Yu-Hai Chen, Mao-Sheng Ran, Mao-Sheng Ran

“…A clinically practical nomogram was built to assess the risk of aggressive behavior in individuals with schizophrenia in rural China, which may facilitate early detection and intervention of these individuals, particularly in rural areas with limited resources. …”
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New strategies and advancements in the synthesis of metal organic frameworks for PAHs removal by Cong Thanh Nguyen, Edgar N. Tec-Caamal, Arunadevi Natarajan, Nguyen Chi Thanh

“…Advancing an innovative technology for detecting and capturing PAHs is essential for safe, and sustainable living. …”
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Distance Conversion Factors for In Situ H-Field Emissions Tests by Jordi Sole-Lloveras, Yasutoshi Yoshioka, Manuel Anon-Cancela, Thilo Kootz, Ferran Silva, Marco A. Azpurua

“…An algorithm is developed to extract the H-field strengths normalized to the reference distance and then, through methods for optimal detection of changepoints, such a normalized curve is fitted to a piece-wise linear function that becomes the generalized distance conversion factor, presented in the form of simplified equations. …”
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From Lab to Life: Self‐Powered Sweat Sensors and Their Future in Personal Health Monitoring by Nan Gao, Guodong Xu, Gang Chang, Yuxiang Wu

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Bioinformatics analysis of potential pathogenesis and risk genes of neuroinflammation-promoted brain injury in intracerebral hemorrhage by Ilgiz Gareev, Ozal Beylerli, Elmar Musaev, Chunlei Wang, Valentin Pavlov

“…TargetScan, miRDB, and RNA22 were used to investigate the miRNAs regulating the DEGs. The functional annotation of DEGs was performed using Gene Ontology (GO) resources, and the cell signaling pathway analysis of DEGs was performed using the Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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Cloning and expression of a C3H-type zinc finger protein gene BoCCCH2 from Brassica oleracea var. italica by JIANG Ming, LIU Qing’e, ZHANG Yanru, ZHU Qi, GONG Xiu, YU Keke, ZHOU Xiuqian

“…Cloning and expression analysis of BoCCCH2 provide evidence for further studies on gene function.…”
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Applying bioinformatic analysis for prognostic assessment of the <i>HS3ST6</i> missense mutations clinical significance in the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. R. Denisova, N. S. Podchernyaeva, A. A. Totolian

“…Currently, mutations in the HS3ST6 gene remain poorly understood; only one missense mutation (p.Thr144Ser, rs746467957) associated with the development of HAE has been described.The aim of our work was to study new mutations in the HS3ST6 gene and analyze in silico their prognostic nature and clinical significance for the development of hereditary angioedema.The material was whole blood samples obtained from 13 patients with symptoms of hereditary angioedema without reduced levels and function of C1-INH.Whole exome sequencing of patients, bioinformatic analysis of HS3ST6 gene mutations using a number of databases and Web resources to predict the effect of mutations on the protein and assess the conservatism of the positions of the mutations detected was involved in study methods.Mutations in the HS3ST6 gene were identified in four patients, including two cases with two mutations simultaneously. …”
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Chronic Kidney Disease: Bridging Conventional Therapeutics and Emerging Molecular Innovations by Shao-feng Wang, Jie Gong, Hai-ying Zhang, Hao-jun Dai, Jin-jin Shi, Jing-wen Ling, Ke-qing Dong, Rosnani Hashim

“…The shortcomings of current approaches highlight the need for strategies to mitigate disease progression and restore renal function, particularly during the early phases of the disease. …”
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Induced Acidic chitinase Expression and Scab-Resistant in Wheat Under Field Condition by S.S. Ramezanpour

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Are Supernovae Responsible for the Gamma Ray Spectrum from the Galactic Center? by Todor Stanev

“…We discuss the supernova remnants distribution as a function of the galactic longitude and compare their positions to that of the detected TeV gamma ray sources. …”
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CRISPR-Cas- and Aptamer-based Systems for Diagnosing Pathogens: A Review by Helin Yu, Wenwen Jing, Xunjia Cheng

“…Finally, we discuss Cas14-based tools as functionally stronger platforms for the detection of non-nucleic acid targets.…”
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