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Discovery of candidate functional non-coding mutations in acute myeloid leukemia using single-cell chromatin accessibility sequencing
Published 2025-05-01“…Additionally, we develop eMut, an integrated computational pipeline for detecting, imputing, and functionally characterizing non-coding mutations in CREs at the single-cell level. …”
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583
AI-Driven Integration of Deep Learning With Lung Imaging, Functional Analysis, and Blood Gas Metrics for Perioperative Hypoxemia Prediction
Published 2025-08-01“… This viewpoint article explores the transformative role of artificial intelligence (AI) in predicting perioperative hypoxemia through the integration of deep learning with multimodal clinical data, including lung imaging, pulmonary function tests, and arterial blood gas (ABG) analysis. …”
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584
Identification and Functional Testing of ERCC2 Mutations in a Multi-national Cohort of Patients with Familial Breast- and Ovarian Cancer.
Published 2016-08-01“…Ten out of eleven mutations that were tested exemplarily in cell-based functional assays exert diminished excision repair efficiency and/or decreased transcriptional activation capability. …”
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585
Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas.
Published 2012-01-01“…In summary, we provide an extensive list of cellular and viral miRNA targets representing an important resource to decipher KSHV miRNA function.…”
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586
Nutritional and Functional Characterization of Flour from Seeds of Chañar (<i>Geoffroea decorticans</i>) to Promote Its Sustainable Use
Published 2025-03-01“…A high polyphenol and dietary fiber content was detected. Flavonoids and condensed tannins were the dominant phenolics. …”
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587
Saponins from <i>Solanum nigrum</i> L. Fruit: Extraction Optimization, Structural Characterization, and Dual-Functional Efficacy
Published 2025-07-01“…., a widely consumed Asian medicinal edible plant, is a promising source of bioactive saponins for functional food applications. …”
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588
Compact Laser-Induced Fluorescence Detector with Adjustable Laser Focal Spot for Multiple Purposes
Published 2024-09-01“…The influence of the excitation power on the detection limit was studied through experiments, and the configuration results for LED/LD as light sources and 487/450 nm wavelengths were compared and optimized. …”
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589
The NASA Exoplanet Archive and Exoplanet Follow-up Observing Program: Data, Tools, and Usage
Published 2025-01-01Get full text
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590
Enhanced high-sensitivity multi-layer neutron detector based on LiF:ZnS(Ag) scintillator
Published 2024-12-01“…Our experiments demonstrate a significant improvement in detection efficiency compared to the single-layer setup. …”
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591
Rapid Detection of Trace Toxicants in Blood Using Thermal Desorption Coupled to Continuous Atmospheric Pressure Interfaced Ion Trap Mass Spectrometry
Published 2025-07-01“…Given its cost-effectiveness and ease of operation, this instrument holds significant potential for widespread application in county-level hospitals with limited analytical resources, enabling rapid diagnosis of acute poisoning, real-time monitoring of drug levels, and disease detection. …”
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592
PATHOLOGICAL SIGNS OF EPILEPTIC AND NON-EPILEPTIC ORIGIN DETECTED IN AWAKE/SLEEP EEG PATTERNS DURING OUTPATIENT AND INPATIENT MONITORING: PROBLEMS OF INTERPRETATION
Published 2017-08-01“…Secondly, a loss of function can be caused by a continuous discharge activity of brain neurons. …”
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593
High accuracy identification of maize seed varieties based on a lightweight improved YOLOv8
Published 2025-05-01“…Lastly, the loss function was replaced with Inner_SIoU, which was more suitable for small-object detection tasks. …”
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594
Revealing Potential Initial Mass Function Variations with Metallicity: JWST Observations of Young Open Clusters in a Low-metallicity Environment
Published 2024-01-01“…A total of 52 and 91 sources were extracted in mass- A _V -limited samples in the two clusters, from which initial mass functions (IMFs) were derived by model-fitting the F200W band luminosity function, resulting in IMF peak masses (hereafter M _C ) $\mathrm{log}{M}_{C}/{M}_{\odot }\simeq -1.5\pm 0.5$ for both clusters. …”
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595
Executive Functions Assessment Based on Wireless EEG and 3D Gait Analysis During Dual-Task: A Feasibility Study
Published 2024-01-01“…Executive functions (EFs) are neurocognitive processes planning and regulating daily life actions. …”
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596
HGCS—A Multiplex Transmission Method for Wide-Area Unmanned Aerial Vehicle Cluster Inspection Data in Hybrid Networked Transmission Lines
Published 2024-01-01“…The HGCS algorithm in comparison to the existing algorithms uses the innovative hybrid approach, exploiting the strengths of different components to get an optimal balance between computational efficiency and resource utilization. These results show that HGCS is a robust choice to deal with fault detection in less time with a fair distribution of resources.…”
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597
Microbial community structure and diversity of endophytic and rhizosphere of Cypripedium species in Changbai Mountains
Published 2024-01-01“…The diversity of rhizosphere fungi was higher than the diversity of endophytic fungi, C. shanxiense had the highest fungal community richness within four Cypripedium species and predicted that endophytic bacteria had reductive citrate cycle, 3-hydroxypropionate bicycle, and other functions. These endophytes comprise unique Cypripedium plants' microbial community structure in Changbai Mountain (China), providing a direction for further protecting wild Cypripedium resources. …”
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598
Regional Frequency Analysis Using L-Moments for Determining Daily Rainfall Probability Distribution Function and Estimating the Annual Wastewater Discharges
Published 2025-06-01“…RainFA is an easy-to-use and open-source software programmed using Python that can be applied anywhere in the world.…”
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599
An innovative and mass-sensitive quartz tuning fork (QTF) biosensor for GFAP detection: A novel approach for traumatic brain injury diagnosis
Published 2025-08-01“…This biosensor is designed to facilitate the highly sensitive and selective detection of GFAP in human serum. In contrast to conventional neuroimaging methods, which are resource-intensive and frequently inaccessible in emergency situations, this innovative biosensor offers a portable, cost-effective, and efficient alternative for rapid GFAP measurement. …”
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Dip‐Pen Nanolithography‐Based Fabrication of Meta‐Chemical Surface for Heavy Metal Detection: Role of Poly‐Methyl Methacrylate in Sensor Sensitivity
Published 2025-02-01“…The nanosize, the surface‐to‐volume ratio (18.6 and 23.1 μm−1 for DAN‐ and D‐PA‐based ink, respectively), and the binding strength between the ligand and the cation (2.21 and −21.37 kcal mol−1 for DAN‐ and D‐PA‐based ink, respectively) are found to be the source of their high sensitivity, with limit of detection values of 0.40 and 0.30 ppb for DAN and D‐PA, respectively. …”
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