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Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling
Published 2024-12-01“…These improve the cost-effectiveness of HCL to £163,000 per QALY if it is valued using the EAG preferred source, to £121,000 if it is valued using the same source as NG17 and to £109,000 if it is valued using other credible sources. …”
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1602
Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets.
Published 2016-10-01“…Tissue damage is usually regarded as a necessary price to pay for successful elimination of pathogens by the innate immune defense. …”
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1603
Multi-heat keypoint incorporation in deep learning model to tropical cyclone centering and intensity classifying from geostationary satellite images
Published 2025-07-01“…Experimental results, done on a constructed dataset for the Western North Pacific for 2015-2023 collected from the Japanese Himawari 8/9 geostationary satellite and the best track of the World Meteorological Organization (WMO) Regional Specialized Meteorological Center (RSMC) Tokyo - Typhoon Center, indicate that the proposed model successfully detects most TC existences on combined images from three infrared channels. …”
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1604
A universal ground test equipment design for the Chang’e series spacecraft
Published 2025-07-01“…To address these issues, this paper proposes a universal ground testing device that integrates remote control and telemetry communication, scientific data transmission, as well as AD (Analog-to-Digital) and OC (Open Collector) signal detection, and DA (Digital-to-Analog) and Open Collector signal output functions through a modular architecture. …”
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1605
An Electrolyte‐Gated InGaZnO Phototransistor that Emulates Visual Experience‐Dependent Plasticity
Published 2025-04-01“…By utilizing the light‐history‐dependent property of the IGZO electrolyte‐gated transistor and following the triplet‐spike‐timing‐dependent plasticity (STDP) rules, the BCM learning rule is successfully emulated in a single device. Moreover, the light‐history‐dependent property enables a variety of bionic vision functions including image edge detection and associative memory. …”
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1606
Pregnancy-acquired memory CD4+ regulatory T cells improve pregnancy outcome in mice
Published 2025-07-01“…Abstract Subsequent pregnancies are generally less prone to obstetric complications. A successful pregnancy outcome requires pivotal immunological adaptation to ensure immune tolerance towards the foetus. …”
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1607
Preliminary high-dose irradiation of the recipient and associated damage of bone marrow stromal compartment enables bone marrow stroma transplantation
Published 2025-07-01“…We hypothesized that a necessary condition for successful MSCs transplantation is the prior significant damage to the recipient’s BM stroma. …”
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1608
Multi-Template Molecularly Imprinted Polymers Coupled with a Solid-Phase Extraction System in the Selective Determination of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in Envir...
Published 2025-05-01“…A systematic study of the mt-MIP composition was conducted using a second-order simplex lattice experiment design (fraction of the functional monomer methacrylic acid (MAA), the total moles of functional monomers, and the total moles of the cross-linker agent). …”
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1609
Developing an ISO11783-compliant prescription map for variable rate spraying in vineyards based on 3D canopy reconstruction
Published 2025-03-01“…This correlation's linear regression was used to calculate dose rates, leading to the successful development of a grid-based prescription map in ISO-XML format, compatible with ISOBUS Task Controller functionality. …”
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1610
Method and metrological characteristics of measuring the mass fraction of monosodium glutamate in biological matrices
Published 2022-10-01“…The production of dietary meals and the increase of food assortment, including food produced from low-quality ingredients, led to the manufacturer’s necessity to use a large number of functional ingredients, i. e. those that improve taste of the food. …”
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1611
Label-free masterful spectrofluorimetric systems for minuscule tracking of natural antioxidant vincamine in the pharmaceutical, environmental, and biological samples: Comparative g...
Published 2025-12-01“…In addition, the two submitted procedures were successfully executed to check VN through weight variation testing in the Brain-ox® capsules with good acceptance values. …”
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1612
The Optimization of PID Controller and Color Filter Parameters with a Genetic Algorithm for Pineapple Tracking Using an ROS2 and MicroROS-Based Robotic Head
Published 2025-03-01“…The experimental results demonstrate that the robot successfully tracks a moving pineapple. Additionally, the color segmentation filter can be further optimized to detect other textured fruits, such as soursop and melon. …”
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1613
Effects of aspirin and omega-3 fatty acids on age-related macular degeneration in ASCEND-Eye: a randomised placebo-controlled trial in a population with diabetes
Published 2025-02-01“…Reports of AMD diagnoses were sourced from 6 monthly ASCEND follow-up questionnaires and a Visual Function Questionnaire.Participants 15 480 UK adults at least 40 years of age with diabetes but no evident cardiovascular disease.Interventions 100 mg aspirin daily versus placebo and, separately, 1 g omega-3 FAs daily versus placebo.Main outcome measure The first post-randomisation reports of AMD.Results During 7.4 years of follow-up, 122 (1.6%) participants randomised to aspirin were reported as having AMD, compared with 138 (1.8%) randomised to placebo (rate ratio 0.88; 95% CI 0.69 to 1.12; p=0.31). …”
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1614
Stent-induced hypersensitivity leading to refractory in-stent restenosis: a case report
Published 2025-03-01“…After over 2 years of follow-up, her cardiac function had significantly improved, and the bridging vessels remained patent, as confirmed by computed tomography angiography. …”
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1615
Cerebrovascular complication of infective endocarditis complicated with abdominal trauma
Published 2016-10-01“…On cranial MRI, multiple infarct areas were detected in both hemispheres and minimal hemorrhagic focus was found in the left temporal region. …”
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1616
The Association of Prothrombin Gene Mutations and Cytomegalovirus Infection with Abortion Among Iraqi Women
Published 2022-08-01“…The prothrombin gene is one of the essential causes that trigger blood clotting and the function of abortion women, therefore the aim of the study is to detect and associate Cytomegalovirus and prothrombin gene mutation (Gene ID: 14061 in NCBI) with abortion through genetic and immunological methods. …”
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1617
Altered Memory T-Cell Responses to Bacillus Calmette-Guerin and Tetanus Toxoid Vaccination and Altered Cytokine Responses to Polyclonal Stimulation in HIV-Exposed Uninfected Kenyan...
Published 2015-01-01“…Implementation of successful prevention of mother-to-child transmission of HIV strategies has resulted in an increased population of HIV-exposed uninfected (HEU) infants. …”
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1618
Organic cation transporter 3 on neuronal mitochondria mediates MPP+-induced mitochondrial dysfunction and neurotoxicity in a TIMM22-dependent manner
Published 2025-07-01“…Abstract Background Mitochondria play crucial roles in cellular metabolism, and metabolite compartmentalization significantly impacts mitochondrial function and disease pathophysiology. MPP+ accumulation in mitochondria, a key factor in MPTP-induced neurodegeneration, leads to mitochondrial dysfunction, such as respiratory chain inhibition, ultimately leading to neuronal death. …”
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1619
BMSC-derived exosomes promote osteoporosis alleviation via M2 macrophage polarization
Published 2024-11-01“…This study aimed to clarify the regulatory function and molecular mechanism of BMSCs-derived exosomes in osteogenic differentiation and their potential therapeutic effects on osteoporosis. …”
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1620
Dapagliflozin inhibits ferroptosis to improve chronic heart failure by regulating Nrf2/HO-1/GPX4 signaling pathway.
Published 2025-01-01“…Echocardiography was used to assess cardiac function, HE staining to evaluate pathological changes in the heart, Prussia blue staining to observe iron ions in myocardial tissue, and enzyme-linked immunosorbent assay (ELISA) to determine serum levels of the inflammatory factors interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) at the end of week 12 and/or the end of week 16. …”
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