Targeted delivery of doxorubicin to B-cell lymphoma using monoclonal antibody-functionalized Chaetoceros biosilica by Ghazal Salari, Ahmad Shadi, Amirhossein Ahmadi, Javid Esfandyari, Hossein Nikmanesh

“…This study investigates the effectiveness of porous biosilica derived from the diatom Chaetoceros sp., functionalized with hydrophilic GPTMS, labeled with CD-19 antibody, and loaded with doxorubicin in targeting Raji cells, a B lymphoid cell line. …”
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A Microfluidic Device Integrating a Glucose Sensor and Calibration Function for Cell-Based Assays by Laner Chen, Kenta Shinha, Hiroko Nakamura, Kikuo Komori, Hiroshi Kimura

“…We have integrated a calibration function that corrects sensor drift, ensuring accurate and prolonged short-term measurement stability. …”
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Functional analysis of stress-related transcription factor gene PsDREB from Paeonia suffruticosa by LIU Huichun, MA Guangying, ZHU Kaiyuan, ZOU Qingcheng, ZHOU Jianghua, TIAN Danqing

“…Subsequently, the PsDREB gene was transferred into tobacco and was mediated by Agrobacterium to determine its biological function in response to adversity. Thereafter, the tolerance ability of the transgenic tobacco was detected under manipulated drought, low temperature, high salt, and abscisic acid (ABA) treatments, as compared to controls.In conclusion, the PsDREB protein has strong binding and transcriptional activities. …”
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Proteolysis and volatile compounds in Mediterranean buffalo milk blue cheese: Quality determinants and functional peptides by Federica Della Cerra, Giuseppina Garro, Rosaria Cozzolino, Sabrina De Pascale, Mariapia Esposito, Gianluca Picariello, Simonetta Caira, Andrea Scaloni, Francesca Marino, Francesco Addeo

“…This study explores the proteolytic changes and volatile organic compound (VOC) profiles occurring during the ripening of Mediterranean buffalo milk blue cheese.The main objective was to characterize bioactive peptides, casein phosphopeptides, and volatile compounds and to assess their potential implications for functional food development.Peptide profiling was conducted using nanoLC-ESI-MS/MS and MALDI-TOF-MS, while VOCs were analyzed via headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry (HS-SPME)-GC-MS.β-casein emerged as the predominant source of bioactive peptides, including sequences with predicted ACE-inhibitory, antimicrobial, and antioxidant activities. …”
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A comprehensive machine learning for high throughput Tuberculosis sequence analysis, functional annotation, and visualization by Md. Saddam Hossain, Md. Parvez Khandocar, Farzana Akter Riti, Md. Yeakub Ali, Prithbey Raj Dey, S M Jahurul Haque, Amira Metouekel, Atrsaw Asrat Mengistie, Mohammed Bourhia, Farid Khallouki, Khalid S. Almaary

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Development of Mango-Mentha functional ready-to-serve (RTS) beverage and its shelf-life evaluation by Sonam Kumari, Abhishek Dutt Tripathi, Alisha Nandan, Arunima Tripathi, Aparna Agarwal

“…The study concludes that the optimized Mango-Mentha RTS drink successfully integrates nutritional and medicinal attributes with desirable sensory characteristics, making it a stable and acceptable functional beverage over two months of storage. …”
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Fermented Buffalo Milk with Conjugated Linoleic Acid-Producing Bacteria: Strain Selection and Functional Applications by Bruna Samara dos Santos Rekowsky, Lorena Brandão Rocha Martinez Fernandez, Katherine Gutierrez Alzate, Carini Aparecida Lelis, Marcelo Resende de Souza, Carolina Oliveira de Souza, Bruno Dutra da Silva, Carlos Adam Conte-Júnior, Carla Paulo Vieira, José Givanildo da Silva, Marion Pereira da Costa

“…Buffalo milk is a rich source of precursor fatty acids for bioactive compounds and provides an optimal environment for bacterial growth. …”
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Functional kombucha production from fusions of black tea and Indian gooseberry (Phyllanthus emblica L.) by Haruthairat Kitwetcharoen, Yupaporn Phannarangsee, Preekamol Klanrit, Sudarat Thanonkeo, Patcharaporn Tippayawat, Poramaporn Klanrit, Poramate Klanrit, Mamoru Yamada, Pornthap Thanonkeo

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A novel rhodamine 6G-based chemosensor for Fe3+ detection in water samples and cellular imaging by Bao-Long Hou, Wenyu Li, Ruirui Feng, Xiumei Yang, Jianli Liu, Cuiling Wang

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SDKU-Net: A Novel Architecture with Dynamic Kernels and Optimizer Switching for Enhanced Shadow Detection in Remote Sensing by Gilberto Alvarado-Robles, Isac Andres Espinosa-Vizcaino, Carlos Gustavo Manriquez-Padilla, Juan Jose Saucedo-Dorantes

“…To address these issues, this study proposes the Supervised Dynamic Kernel U-Net (SDKU-Net), a novel architecture designed to enhance shadow detection in complex remote sensing scenarios. SDKU-Net integrates dynamic kernel adjustment, a combined loss function incorporating Focal and Tversky Loss, and optimizer switching to effectively tackle class imbalance and improve segmentation quality. …”
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Tackling the Optimal Phasor Measurement Unit Placement and Attack Detection Problems in Smart Grids by Incorporating Machine Learning by Ramzi Al-Sharawi, Abdelfatah Ali, Mostafa Shaaban, Nasser Qaddoumi, Mohamed S. Abdalzaher

“…These results highlight the success of our framework in concurrently optimizing attack detection performance, topological observability, and system cost.…”
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Edge enhancement of potential field data using the enhanced gradient (EG) filter by Ahmad Alvandi, Korimilli N Durga Prasad, Hazel Deniz Toktay

“…Potential field data play a critical role in interpreting various geologic structural features through edge detection filters that aid in mapping subsurface structural features. …”
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Fluorescent carbon quantum dots from Syzygium aromaticum as a selective sensor for Fe3+ and Cd2+ detection in aqueous solution by Said Ali Akbar, Muhammad Hasan, Muhammad Nazar, Ilham Zulfahmi, Edy Miswar, Muhammad Iqhrammullah, Zulkarnain Jalil

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The impact of obesity and weight loss treatment on metabolic parameters, cardiovascular autonomic and sensory nerve function and in vitro fertilization outcomes in infertile women:... by Anna Vágvölgyi, Viktor Vedelek, Nóra Keller, Dalma Szöllősi, Szilvia Lada, Attila Nemes, Péter Kempler, Adrienn Menyhárt, István Baczkó, Tamás Várkonyi, Csaba Lengyel, János Zádori

“…Our study aimed to analyze the effects of preconceptional weight loss in infertile women with obesity on peripheral sensory and cardiovascular autonomic nerve function, metabolic parameters, and the success of in vitro fertilization (IVF).MethodsA retrospective cohort study included women with obesity and infertility undergoing weight optimization before IVF, alongside age-matched controls. …”
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A high‐throughput RNAi screen for detection of immune‐checkpoint molecules that mediate tumor resistance to cytotoxic T lymphocytes by Nisit Khandelwal, Marco Breinig, Tobias Speck, Tillmann Michels, Christiane Kreutzer, Antonio Sorrentino, Ashwini Kumar Sharma, Ludmila Umansky, Heinke Conrad, Isabel Poschke, Rienk Offringa, Rainer König, Helga Bernhard, Arthur Machlenkin, Michael Boutros, Philipp Beckhove

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Deep Defense Against Mal-Doc: Utilizing Transformer and SeqGAN for Detecting and Classifying Document Type Malware by Gati Lother Martin, Sang-Min Lee, Jong-Hyun Kim, Young-Seob Jeong, Ah Reum Kang, Jiyoung Woo

“…The proposed model will solve this gap by detecting and classifying document-type malware families using script codes, including tags, to write documents and script languages to execute malicious functions. …”
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DMM-YOLO: A high efficiency soil fauna detection model based on an adaptive dynamic shuffle mechanism by Jiehui Ke, Renbo Luo, Guoliang Xu, Yuna Tan, Zhifeng Wu, Liufeng Xiao

“…Abstract Soil fauna play a critical role in maintaining ecosystem functions and assessing environmental health, making accurate and efficient detection essential. …”
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Correlation between D-dimer and size of middle cerebral artery infarction and its relation to functional outcome by Ramy Taha Alloush, Mohamed Hamdy Ibrahim, Shahinaz Mohamed Helmy, Aya Ebrahim Marwan, Mona Ali Eissa, Adel T. Alloush, Mohamed Khaled Elewa

“…Furthermore, data from neuroimaging, clinical, laboratory, and demographic sources were examined. Additionally, the modified Rankin Scale (mRS) score was used to evaluate the predictive usefulness of plasma D-dimer on a patient's functional outcome after three months. …”
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Simple surface modification of poly(methyl methacrylate) microfluidic microplates for enhanced ultrasensitive multiplexed detection of infectious diseases by Sharma T. Sanjay, Sapna Kannan, XiuJun Li

“…Herein, we report a simple method of functionalization of poly(methyl methacrylate) (PMMA) with polylysine to be used as the microfluidic microplate substrate for enhanced ELISA, enabling rapid, ultrasensitive, and multiplexed detection of infectious diseases. …”
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Plasmonic optical fiber biosensors for ultra-low detection of respiratory syncytial virus via point-of-care tests by Federica Passeggio, Luigi Zeni, Massimiliano Galdiero, Francesco Arcadio, Carla Zannella, Anna De Filippis, Chiara Marzano, Ines Tavoletta, Fabiana Napolitano, Rosalba Pitruzzella, Giuseppe Portella, Nunzio Cennamo

“…Hence, the results establish the POF-based RSV biosensor as a sensitive, cost-effective, ultra-fast, capable of being connected to the Internet, and a scalable alternative to traditional RSV detection methods, offering a promising tool for improving diagnostic capabilities in clinical and resource-limited settings.…”
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