Untargeted metabolomics reveals stage-specific metabolic signatures in yak colostrum, transitional milk and mature milk by Yunduan Wang, Daoliang Lan, Shaohui Beng, Shunyang Liu, Xueer Mu, Kechao Chen, Yueyue Li, Meng Xu, Jian Li, Wei Fu

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The profound implications of mitochondrial myopathy on activities of daily living: an observational qualitative study of standardized structured and semi-structured patient intervi... by Elizabeth M. McCormick, James T. Peterson, Joaquim Diego D. Santos, Jean Flickinger, Rui Xiao, Richard Haas, Zarazuela Zolkipli-Cunningham

“…Our results will serve as a comprehensive resource to inform the physician, patient, industry and advocacy communities on outcome measure selection and clinical trial design; and to help inform regulatory agencies in the United States Food and Drug Administration (FDA) drug approval process for MM.…”
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FORECASTING THE GROUNDWATER LEVEL OF CEMENT RAW MATERIALS DEPOSIT BASED ON DYNAMIC NEIGHBORHOOD MODELS by I. A. Sedykh

“…The software using C++ is developed for the parametric identification and simulation of the functioning of the dynamic neighborhood model under consideration. …”
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Solid-State Nanopore Readout of Programmable DNA and Peptide Nanostructures for Scalable Digital Data Storage by Lihuan Zhao, Jiajun Wang, Lin-Sheng Wu, Xin Zhao

“…Peptide nanostructures are introduced as a data medium via click-chemistry, expanding encoding sources. By integrating a photosensitive PC-linker, this approach endows the data chain with functionalities for encryption and data formatting, enhancing the security and organization of biological information storage. …”
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The Pore Diffusion Coefficient of Iodide Ion in Rock Samples Using X-ray K-edge Imaging by Jiujiang ZHAO, Zhe WANG, Zhidu ZHANG, Hong ZHAO

“…When the contamination source is removed after remediation, the contaminated porewater can be a long-term contamination source to the groundwater in fractures via back diffusion. …”
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SIU-ICUD: Principles and Outcomes of Focal Therapy in Localized Prostate Cancer by Alessandro Marquis, Jonathan Olivier, Tavya G. R. Benjamin, Eric Barret, Giancarlo Marra, Claire Deleuze, Lucas Bento, Kae J. Tay, Hashim U. Ahmed, Mark Emberton, Arnauld Villers, Thomas J. Polascik, Ardeshir R. Rastinehad

“…Cancer control rates vary by energy modality, tumor characteristics, and institutional experience, demonstrating comparable outcomes to radical treatments in well-selected patients. The safety profile is excellent, with high rates of urinary continence and sexual function preservation. …”
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Current approaches to assessment of the impact of the environmental contamination on cancer risk by L. G. Solenova

“…Assessment of the impact of environmental contamination on cancer risk includes: •setting research priorities on the local, regional, and on the all-Russian levels; •the selection of the research that may be maximally socially profitable; •the choice of the research method that the most adequately meets the research objectives; •systemic analysis of the planed research to determine the availability of the resources, personnel, and information; •monitoring of atmospheric pollutions with analysis of the fraction composition of the particulate matters; •coordination of available data basis on environment and the population health conditions; •the implementation of the of molecular biology to determine prenosological manifestation of carcinogenesis and development of fine and diverse research methods on relationships between the environment and cancer risk.For effective implementation of the research objectives aimed to decrease the impact of hazard factors with special reference on cancer risk in the Russian population, it is necessary: to create training personnel capable of providing epidemiologic studies, using up-to day methods, publication of methodological materials, text books, and sufficient funding of studies.…”
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Information Assisted Dictionary Learning for fMRI Data Analysis by Manuel Morante, Yannis Kopsinis, Sergios Theodoridis, Athanassios Protopapas

“…Moreover, it can cope efficiently with uncertainties in the modeling of the hemodynamic response function. In addition, the method bypasses one of the major drawbacks of the DL methods; namely, the selection of the sparsity-related regularization parameters. …”
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Background of standardization and regulation of training and use of pharmaceutical regular resource potential in XI–XVI centuries by M. S. Ponomarenko, O. S. Soloviov, T. M. Krasnianska, Yu. M. Grygoruk

“…The main stages of development of the property (material) and human resources to provide medical treatment and patients have been detected. The basic steps of transformation and delimitation of professional functions pharmacist-physician have been set. …”

Investigation and Application of Water-Saving Monitoring Technology in Public Institutions by WANG Kang, ZHENG Yongjie, ZHANG Zhen, TANG Yanping, SONG Wenhao, GUO Xiaoming

“…Considering the characteristics of water use and the current situation of water facilities in public institutions,this study comprehensively employs the Internet of Things (IoT),cloud deployment,databases,three-dimensional (3D) visualization,and other advanced techniques to create a water-saving reconstruction scheme with integrated software and hardware for public institutions.Therefore,a smart water management platform for public institutions is built to implement advanced water-saving concepts and improve the water management level.The main research results are as follows:① By intelligent remote monitoring equipment,the multiclass water measurement network is designed to realize the fine collection of zonal water use data;② this study designs a reconstruction scheme of water facilities and explores the utilization mode of unconventional water sources to improve the utilization efficiency of water resources;③ multiple algorithms and statistical methods are used to analyze the time series of water use data,and thus this study realizes the analysis of pipeline network leakage and damage,identification of water use anomalies,and water-saving statistical analysis,and the investigation of water use laws;④ the platform with functions of monitoring and early warning is established to achieve real-time remote monitoring of water use,statistical analysis of historical water use,and identification and warning of pipe network leakage,so as to detect water anomalies in time and save water.The research results are first applied to the construction of the water-saving institution of the Pearl River Water Resources Commission to build a benchmark for the construction of water-saving institutions in the southern region.On the basis of application experience,the comprehensively integrated monitoring technology for water-saving in public institutions is developed,which provides a new idea for public institutions to save water.…”
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Analysis of value-based healthcare (VBHC) framework by incremental cost-effectiveness of surgical and therapeutic interventions: a retrospective study at tertiary private health gr... by Mona Khamis, Zainab Almoosa, Marie Santos, Engineer Diaa Kamal, Suhail Yaghmor, Muhammad Daniyal, Abbas Al Mutair

“…Knee and ACL therapies were the most cost-effective, while lower cost-effectiveness in CP and LBP treatments may stem from the chronic nature, variable patient responses, and high resource use. Improving patient selection, standardizing treatment protocols, and enhancing early intervention and care coordination can boost efficiency and outcomes. …”
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Identification and assessment of threats to the financial security system of the state in the field of customs control by O.M. Petruk, Yu.S. Kostishin

“…The purpose of this article is to identify and assess threats to the financial security of the state in the customs sphere, the source of which is the inefficient functioning of the customs control mechanism. …”
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Comparative analysis of statistical software products for the qualifying examination of plant varieties suitable for dissemination by Н. В. Лещук, К. М. Мажуга, Н. С. Орленко, Є. М. Стариченко, Є. А. Шкапенко

“…The both packages were widely used in the world for statistical data processing, they have similar functions for statistics calculation. Conclusion. …”
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Peripheral blood cells enriched by adhesion to CYR61 are heterogenous myeloid modulators of tissue regeneration with early endothelial progenitor characteristics by M Herrmann, J Schneidereit, S Wiesner, M Kuric, M Rudert, M Lüdemann, M Srivastava, N Schütze, R Ebert, D Docheva, F Jakob

“…Introduction: Circulating precursor cell populations of various lineages have been identified with putative functions in tissue regeneration, which may have potential for cell based individual regenerative strategies. …”
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Sap flow simulation of Cunninghamia lanceolata in degraded red soil region based on back propagation neural network by Tu Jie, Liu Qijing, Wei Jun, Hu Liang

“…Therefore, quantitative research on tree water consumption characteristics by transpiration has become a hot issue in the field of tree physiological ecology in recent years.Taking the C. lanceolata plantation in degraded red soil of Jiangxi Province as the research object, the log-sigmoid type function (tansig) of MATLAB toolbox was selected as the transmission function for the role of neurons. …”
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Glucose Sensing in Saliva by Jacopo Giaretta, Riccardo Zulli, Theja Prabhakar, Ronil J. Rath, Sina Naficy, Sara Spilimbergo, Paul S. Weiss, Syamak Farajikhah, Fariba Dehghani

“…Abstract Glucose plays critical roles in many human body functions, above all as a source of energy. Abnormal levels of glucose are correlated to different diseases, importantly including diabetes. …”
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Quadruped Robots: Bridging Mechanical Design, Control, and Applications by Qimeng Li, Franco Cicirelli, Andrea Vinci, Antonio Guerrieri, Wen Qi, Giancarlo Fortino

“…To understand their impact on performance and functionality, key aspects of mechanical design are analyzed, including leg configurations, actuation systems, and material selection. …”
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Integration of artificial intelligence and advanced optimization techniques for continuous gas lift under restricted gas supply: A case study by Leila Zeinolabedini, Forough Ameli, Abdolhossein Hemmati-Sarapardeh

“…In addition, the net present value (NPV) serves as the objective function. To optimize the selected input variables, including tubing inside diameter, gas injection rate, and separator pressure, various optimization algorithms such as particle swarm optimization (PSO), ant colony optimization (ACO), genetic algorithm (GA), and a Novel optimization algorithm in a gas-lift study called grey wolf optimization (GWO), were utilized considering the constraint of the limited available gas. …”
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Harmonic State Estimation Method Based on Bayesian Optimized Elastic Network Regression by Siqi MA, Zhong WANG

“…Firstly, when the least square method is used to estimate the harmonic state, the weighted 1-norm and 2-norm are added to the penalty function at the same time; In addition, in order to estimate the harmonic state more efficiently and accurately, the Gaussian process and Bayesian optimization are applied to select the weight of 1-norm and 2-norm; Finally, the effectiveness of the proposed method is verified in IEEE14 node. …”
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Recent advances in microalgae-driven carbon capture, utilization, and storage: Strain engineering through adaptive laboratory evolution and microbiome optimization by Zhongshi He, Jing Wang, Yantao Li

“…In microalgae, ALE has been employed to improve resilience against varying environmental and stress factors and increase carbon capture efficiency, and for the production of valuable bioproducts through gradual accumulation of beneficial mutations following manual or automated selection. Furthermore, advancements in the understanding of microbial symbiotic relationships in the phycosphere have facilitated microbiome optimization in microalgal cultivation systems, significantly improving their functionality and productivity. …”
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