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GzESTY as an optimized cell-based assay for initial steps in GPCR deorphanization
Published 2025-05-01“…Orphan GPCRs, lacking identified natural ligands, are a high priority for research, as identifying their ligands will aid in understanding their functions and potential as drug targets. Most GPCRs, including orphans, couple to Gi/o/z family members, however current assays to detect their activation are limited, hindering ligand identification efforts. …”
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Laparoscopic resection of idiopathic jejunal arteriovenous malformation after metallic coil embolization
Published 2018-07-01“…We present a case of a jejunal AVM successfully treated with the combination of metallic coil embolization and laparoscopic surgery. …”
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High-resolution genetic and physical mapping reveals a peanut spotted wilt disease resistance locus, PSWDR-1, to Tomato spotted wilt virus (TSWV), within a recombination cold-spot...
Published 2025-03-01“…Sequencing of these two recombinants confirmed the cold spot with only five SNPs detected within this region. Conclusions This study successfully identified a peanut spotted wilt disease resistance locus, PSWDR-1, on chromosome A01 within a recombination “cold spot”. …”
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A hybrid framework of generative deep learning for antiviral peptide discovery
Published 2025-07-01“…The performance of the WGAN-GP model was comprehensively evaluated, confirming its ability to produce diverse and functional peptide sequences. The model successfully generated and identified 815 novel AVPs, demonstrating its effectiveness in peptide generation and classification. …”
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Differentiation of mtDNA Methylation in Tissues of Ridgetail White Prawn, <i>Exopalaemon carinicauda</i>
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2468
Faunistic analysis of insects of Deva Vatala National Park and agroecosystem of Gujrat Pakistan
Published 2023-01-01“… Insect biodiversity drives ecological functioning and provides ecosystem services in different landscapes. …”
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Predicting the course of localized periodontitis of traumatic etiology after complex treatment
Published 2024-03-01“…Conventional approaches to treatment are not always successful and do not necessarily provide a lasting effect. …”
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Optimization of the Preparation Process of Flavonoid Solid Beverage from Ficus hirta Vahl.
Published 2025-05-01Get full text
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Towards a comprehensive view of wetland benthic communities
Published 2025-01-01“…Benthic prokaryotic communities, utmost important for wetlands and marine environments functioning, are influenced by physical-chemical parameters and interactions with other communities, especially micro-eukaryotes and meiofauna. …”
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Machine learning-enabled multiscale modeling platform for damage sensing digital twin in piezoelectric composite structures
Published 2025-02-01“…Abstract Nondestructive evaluation (NDE) of aerospace structures plays a crucial role in their successful operation under harsh environments. Most NDE methods, however, lack real-time in-situ predictive capabilities of evolving damage and are conducted in a post-mortem manner. …”
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Liquid Chromatography–Mass Spectrometry Application for Metabolomic Profiling of Compounds in Mycobacterial Cultures
Published 2023-12-01“…Insight into bacterial cellular composition and functions can be obtained by the application of metabolomics. …”
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De novo transcriptome assembly of the Mediterranean sea-rock pool mosquitoes Aedes mariae and Aedes zammitii
Published 2025-01-01“…Validation by BUSCO confirmed the high quality of our resources. Homology alignments of predicted ORFs showed that 21,842 sequences from Ae. mariae and 21,944 sequences from Ae. zammitii mapped to the Nr, SwissProt, and TrEMBL databases, while 19,208 and 19,393 predicted ORFs, respectively, were functionally annotated using the COG and KEGG databases. …”
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Spatial Appraisal of Seasonal Water Yield of the Sokoto-Rima Basin
Published 2021-08-01“…Understanding the dynamics of water yield as relates to water balance is vital for the functioning of ecosystems as well as model-based computation of their respective ecosystem services. …”
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