Cervical ripening at home or in hospital during induction of labour: the CHOICE prospective cohort study, process evaluation and economic analysis by Mairead Black, Cassandra Yuill, Mairi Harkness, Sayem Ahmed, Linda Williams, Kathleen A Boyd, Maggie Reid, Amar Bhide, Neelam Heera, Jane Huddleston, Neena Modi, John Norrie, Dharmintra Pasupathy, Julia Sanders, Gordon C S Smith, Rosemary Townsend, Helen Cheyne, Christine McCourt, Sarah Stock

“…Impact of COVID-19 Of responding sites, 23% reported a change in the method used for cervical ripening and 28% reported a change in criteria for offering home cervical ripening. …”
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Discontinuation of immune checkpoint inhibitors for reasons other than disease progression and the impact on relapse and survival of advanced melanoma patients. A systematic review... by Konstantinos Lallas, Eftychia Chatziioannou, Derya Durak, Georg Frey, Lina Maria Serna-Higuita, Marie-Lena Rasch, Athanassios Kyrgidis, Eleni Timotheadou, Zoe Apalla, Ulrike Leiter, Lukas Flatz, Lukas Flatz, Aimilios Lallas, Teresa Amaral, Teresa Amaral

“…BackgroundDespite durable responses achieved with Immune Checkpoint Inhibitors (ICIs), data about optimal duration of treatment, especially in the context of adverse events, remain scarce.ObjectiveTo systematically review the evidence concerning the impact of treatment discontinuation with ICIs for reasons other than progressive disease (PD) on relapse rates and survival of melanoma patients.MethodsA systematic literature search was conducted in three electronic databases until July 2024. …”
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Large Language Models and Artificial Neural Networks for Assessing 1-Year Mortality in Patients With Myocardial Infarction: Analysis From the Medical Information Mart for Intensive... by Boqun Shi, Liangguo Chen, Shuo Pang, Yue Wang, Shen Wang, Fadong Li, Wenxin Zhao, Pengrong Guo, Leli Zhang, Chu Fan, Yi Zou, Xiaofan Wu

“…Qwen-2 and Llama-3 are high-performance, open-source large language models (LLMs) available online. …”
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The Effect of Sowing Date on Yield and Quality Characteristics of Autumn Sugar Beet (Beta vulgaris L.) Cultivars in Gonbad Kavous by E Paserakloo, A Biabani, S Yarahamdi, A Saberi, M Naeemi, F Taliei

“…IntroductionIn many countries of the world, sugar production is one of the essential aspects of their agricultural economy, and in the meantime, the sugar beet plant, which is cultivated exclusively as a source of sucrose, plays an important role. In recent years, many studies have been conducted in Iran on various aspects of crop, breed, quality and other agricultural characteristics of autumn sugar beet. …”
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Developing a Machine Learning Model for Predicting 30-Day Major Adverse Cardiac and Cerebrovascular Events in Patients Undergoing Noncardiac Surgery: Retrospective Study by Ju-Seung Kwun, Houng-Beom Ahn, Si-Hyuck Kang, Sooyoung Yoo, Seok Kim, Wongeun Song, Junho Hyun, Ji Seon Oh, Gakyoung Baek, Jung-Won Suh

“…Using these observational health care data, we developed machine learning–based prediction models using the observational health data sciences and informatics open-source patient-level prediction package in R (version 4.1.0; R Foundation for Statistical Computing). …”
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The efficacy and safety of ketorolac for postoperative pain management in lumbar spine surgery: a meta-analysis of randomized controlled trials by Jianbin Guan, Ningning Feng, Kaitan Yang, Haimiti Abudouaini, Peng Liu

“…Data were extracted and analyzed using open-source meta-analysis software OpenMeta-Analyst, focusing on outcomes such as VAS pain scores, postoperative morphine requirements (PMR), length of hospital stay (LOS), and adverse effects, such as nausea, vomiting, pruritus, and constipation. …”
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Image navigator–based, automated coronary magnetic resonance angiography for the detection of coronary artery stenosis by Gregory Wood, Reza Hajhosseiny, Alexandra Uglebjerg Pedersen, Simon Littlewood, Tina Juul Hansen, Radhouene Neji, Karl P. Kunze, Jens Wetzl, Bjarne Linde Nørgaard, Jesper Møller Jensen, Michael Maeng, Per Lav Madsen, Niels Vejlstrup, Claudia Prieto, René M. Botnar, Won Yong Kim

“…Additionally, the study incorporates the utilization of standardized postprocessing with sliding-thin-slab multiplanar reformatting, in combination with evaluation of the source images, to optimize the visualization of coronary artery stenosis. …”
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Performance and Cost-Effectiveness of Computed Tomography Lung Cancer Screening Scenarios in a Population-Based Setting: A Microsimulation Modeling Analysis in Ontario, Canada. by Kevin Ten Haaf, Martin C Tammemägi, Susan J Bondy, Carlijn M van der Aalst, Sumei Gu, S Elizabeth McGregor, Garth Nicholas, Harry J de Koning, Lawrence F Paszat

“…Therefore, the objective of this study was to estimate the cost-effectiveness of lung cancer screening in a population-based setting in Ontario, Canada, and evaluate the effects of screening eligibility criteria.<h4>Methods and findings</h4>This study used microsimulation modeling informed by various data sources, including the Ontario Health Insurance Plan (OHIP), Ontario Cancer Registry, smoking behavior surveys, and the NLST. …”
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Efficacy and safety of oxaliplatin-based chemotherapy as first-line treatment in elderly patients with metastatic colorectal cancer: a meta-analysis by Shaoqing Fan, Zeming Zhao, Haiqian Wang, Handong Wang, Wenbo Niu

“…Subgroup analyses explored heterogeneity sources, including chemotherapy combinations (e.g., bevacizumab, panitumumab).ResultsSeven RCTs (1,839 patients) met inclusion criteria. …”
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Midazolam infusions for therapeutic management of pediatric refractory status epilepticus: a systematic review by K. Taneille Johnson, Ammar AlZadjali, Dawoud Al Nasseri, Jessie Cunningham, Kazuhiro Shoya, Cecil D. Hahn, Cecil D. Hahn, Cecil D. Hahn, John Basmaji, Nicole K. McKinnon, Nicole K. McKinnon, Nicole K. McKinnon, Nicole K. McKinnon

“…ObjectiveWe aim to determine the optimal dosing of midazolam continuous intravenous infusions for the treatment of pediatric refractory status epilepticus (RSE).Data sourcesWe searched Medline ALL, Embase, Embase Classic, Cochrane CENTRAL, and Web of Science in March 2023 and again in February 2024.Study selectionRandomized and non-randomized studies involving pediatric patients who received continuous midazolam for the treatment of RSE were eligible. …”
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An eHealth Intervention to Improve Quality of Life, Socioemotional, and Health-Related Measures Among Older Adults With Multiple Chronic Conditions: Randomized Controlled Trial by David H Gustafson Sr, Marie-Louise Mares, Darcie Johnston, Olivia J Vjorn, John J Curtin, Gina Landucci, Klaren Pe-Romashko, David H Gustafson Jr, Dhavan V Shah

“…Tested moderators were sex, scheduled health care use, and number of chronic conditions. Data sources were surveys at baseline and 6 and 12 months comprising validated scales, and continuously collected ElderTree usage. …”
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Improving nutritional quality and aflatoxin detoxification of peanut meal by co-fermentation with Weizmannia coagulans, Bacillus subtilis, and supplemented enzymes by Youwei Chen, Hao Huang, Dan Li, Limei Zou, Wendi Yu, Weiwei Dong, Xiang Yu, Yanli Feng, Jun Liu, Shumiao Zhao, Yunxiang Liang, Yuanliang Hu, Nan Peng

“…Microbial fermentation is one of the most effective methods to reduce anti-nutritional factors and enhance the nutritional value of peanut meal. …”
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Potential evaluation and development utilization technology of geothermal resources in the Jining Coalfield by Qipeng SHI, Jianguo FAN, Fengfeng SHI, Xuesen WANG, Huiming ZHENG, Jia MENG, Shuailiang SONG

“…Under the guidance of China’s “carbon peaking and carbon neutrality” goals, efforts are underway to optimize and adjust the national energy structure. …”
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Program Report—Transplant Manitoba Adult Kidney Program Cutting Costs, Not Corners: Value of Quality Improvement Initiatives by Christie Rampersad, Aaron Trachtenberg, James Shaw, Nancy Dodd, Krista Maxwell, Martin Karpinski, Chris Wiebe, Peter Nickerson, Julie Ho

“…Methods: To quantify the potential cost savings, we employed a 3-pronged approach. …”
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Outcomes of Living Kidney Donors Following Donor Nephrectomy in Aotearoa New Zealand by Lai Wan Chan, Georgina L. Irish, Tze L. Goh, Basil Alnasrallah, Christopher E. Davies, Matthew P. Sypek, Philip A. Clayton, Michael G. Collins

“…Introduction: Living donor kidney transplantation is the optimal treatment for people with kidney failure (KF). …”
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Assessment of bimodal laser photodynamic therapy at wavelenths of 410 nm and 653 nm for oral precancerous lesions: An in vitro and in vivo study by Shuiting Fu, Ting Zhu, Lu Chen, Guoyu Zhou, Jian Sun

“…There is a pressing demand for innovations that can enhance the effectiveness of PDT and minimize its side effects in addressing oral precancerous lesions. Materials and methods: This study employed m-THPC as a photosensitizer and developed a novel light source with dual wavelengths of 410 nm/653 nm tailored to excite the photosensitizer. …”
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Effects of corn variety in whole-plant corn silage on dry matter intake, average daily gain and gastrointestinal tract bacteria and metabolites in Hu lambs by Jianxin Jiao, Jianxin Jiao, Jianxin Jiao, Shumin Ma, Shumin Ma, Shumin Ma, Ting Jiao, Ting Jiao, Ting Jiao, Shangli Shi, Shangli Shi, Shangli Shi, Yongquan Gao, Yongquan Gao, Yongquan Gao, Xia Zhang, Xia Zhang, Xia Zhang, Shengguo Zhao, A. Allan Degen

“…Understanding how different WPCS varieties influence gastrointestinal microbiota and metabolic profiles is essential for optimizing feed efficiency and animal health.MethodsThis study examined the effects of three corn varieties (2 introduced - Tunyu 168: TY; Yu silage 23: YQZ, and 1 local Longsheng 1: LS) in WPCS on gastrointestinal bacteria and metabolites in lambs. …”
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Identification of Thalictrum squarrosum as an alternate host for Puccinia triticina and pathogen analysis of Thalictrum squarrosum rust by Na Zhao, Na Zhao, Liang Huang, Liang Huang, Jun Ren, Jun Ren, Mengya Zhang, Ting Yi, Ting Yi, Hongfu Li, Hongfu Li, Hao Zhang, Hao Zhang, Bo Liu, Li Gao, Li Gao, Hongfei Yan, Wanquan Chen, Wanquan Chen, Taiguo Liu, Taiguo Liu, Taiguo Liu

“…Our study provides new insights into the sexual cycle of Pt in China and provides a scientific basis for studying the evolution of Pt virulence and optimizing control methods for wheat leaf rust.…”
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High-throughput screening of monoclonal antibodies against carbapenemases using a multiplex protein microarray platform by Sascha D. Braun, Sascha D. Braun, Martin Reinicke, Martin Reinicke, Celia Diezel, Celia Diezel, Elke Müller, Elke Müller, Katrin Frankenfeld, Thomas Schumacher, Hugo Arends, Stefan Monecke, Stefan Monecke, Ralf Ehricht, Ralf Ehricht, Ralf Ehricht

“…However, the development of such assays is often hindered by the time-consuming process of identifying high-affinity antibody pairs.MethodsTo accelerate this process, we evaluated a protein microarray platform as a high-throughput screening tool to identify optimal monoclonal antibody (mAb) pairs targeting the most clinically relevant carbapenemases. …”
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The Effect of Different Levels of Vermicompost and Chemical Fertilizer on some Quantitative and Qualitative Traits of Three Maize (Zea mays L.) Cultivars by Mohammad Akbari, Gholamreza Heidari, Shiva Khalesro, Mohammad Majidi

“…IntroductionMaize is a primary source of food for humans, livestock and industrial purposes. …”
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