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4561
5-aminolevulinic acid photodynamic therapy for the treatment of basal and squamous cell carcinoma: A systematic review
Published 2025-08-01“…We performed a systematic review to assess the efficacy and safety of published ALA-PDT protocols for these conditions. Methods: A PubMed search was conducted through August 8, 2024, to identify studies evaluating 10 % or 20 % ALA-PDT in BCC, SCC, and BD. …”
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4562
GENETIC PREDICTORS OF SEVERITY AND EFFICACY OF COVID-19 PHARMACOTHERAPY
Published 2021-08-01“…The studies aimed at finding predictors of the severe course of this novel coronavirus infection, as well as the factors that determine the efficacy and safety of this disease pharmacotherapy, are acquiring special social significance.The aim of this work is to find and summarize information on genetic predictors of severe COVID-19, as well as pharmacogenetic aspects that determine the variability of the therapeutic response to the drugs recommended for COVID-19 treatment.Materials and methods. The article provides a review of scientific results on the research of gene polymorphism that determine a body’s response to the introduction of SARS-CoV-2 infection and the effects of pharmacotherapy for this disease, obtained from open and available sources within the period of 2019 – March 2021. …”
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4563
Optimalisasi Badan Penasihatan Pembinaan dan Pelestarian Perkawinan Kepenghuluan Dalam Meminimalisir Angka Perceraian
Published 2024-10-01“…However, the effectiveness of its application in various regions in preventing divorce is still limited. This research method uses qualitative research with field research with critical analytical descriptive methods, then this composition uses a normative and empirical approach methodology sourced from direct experience in the field. …”
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4564
Estimation and Forecasting of Nigeria’s Residential, Commercial, and Industrial Electricity Demands
Published 2025-01-01“…These unmet electricity needs are considered sensitive determinants in achieving optimal planning and utilization of electricity in a developing economy like Nigeria. …”
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4565
DFT analysis of the [3 + 2] heterocyclization reaction of ((1,2,4-triazole(1,3,4-oxadiazole)-3(2)-yl)methyl)thiopyrimidines
Published 2025-03-01“…The study’s findings provide a deeper understanding of chemical transformations in heterocyclic systems and can be utilized to optimize synthetic methods in medicine, agrochemistry, and materials science. …”
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4566
Investigating the hatchability and nauplii biometry of Artemia franciscana in unconventional waters of Sistan region, Southeast Iran
Published 2024-03-01“…Introduction: Nowadays, using unconventional water, especially in arid and semi-arid areas, has increased as a result of global population increase, urbanization and climate change. Using these water sources for aquaculture is suggested for optimal utilization and reduction of their adverse effects on the environment. …”
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4567
Direct Disk Diffusion Testing and Antimicrobial Stewardship for Gram-Negative Bacteremia in the Context of High Multidrug Resistance
Published 2025-07-01“…<b>Background:</b> Combining direct disk diffusion (DD) testing with antimicrobial stewardship (AMS) may optimize antibiotic use and improve outcomes in patients with Gram-negative bloodstream infections (GNBSIs). …”
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4568
Characteristics and influencing factors of livestock residue nitrogen, phosphorus, and organic matter discharge and spatial distribution of pollution potential: Case study in the Y...
Published 2025-09-01“…Even low-risk waterways, such as the Yellow River and Xianxian Ditch, posed potential threats to the Bohai Sea. Optimizing breeding scale, flushing intensity, manure cleaning and treatment methods, and farm-river distances can effectively reduce pollution risks.…”
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4569
Study on the evolution mechanism of adiabatic shear bands during the deformation of medium carbon bainitic steel acted upon by high strain rates
Published 2025-03-01“…The microstructure evolution and formation mechanism of adiabatic shear bands of bainitic steel during high strain rate deformation are methodically examined via a split Hopkinson pressure bar. …”
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4570
Experimental determination and theoretical calculation for CO2 liquid-solid phase equilibrium in PLNG
Published 2024-09-01“…Methods A novel liquid-solid phase equilibrium test setup was designed and built with visualization and continuous sampling functions. …”
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4571
Enhancing Voice Activity Detection for an Elderly-Centric Self-Learning Conversational Robot Partner in Noisy Environments
Published 2025-04-01“…In contrast, traditional lightweight rule-based VAD methods tend to yield higher recall but at the expense of precision. …”
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4572
A Comprehensive Review of Crop Chlorophyll Mapping Using Remote Sensing Approaches: Achievements, Limitations, and Future Perspectives
Published 2025-04-01“…Combining physical models with data processing methods, such as artificial intelligence, can improve scalability, cost-effectiveness, and real-time monitoring capabilities.…”
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4573
Advancements in chondrocyte 3-dimensional embedded culture: Implications for tissue engineering and regenerative medicine
Published 2025-04-01“…To address these issues, ongoing studies of many research groups have been focusing on refining culture conditions, optimizing scaffold materials, and exploring novel cell sources such as stem cells to enhance the quality and quantity of engineered cartilage tissues.Although obstacles remain, continuous endeavors to enhance culture techniques and overcome limitations offer a promising outlook for the advancement of more efficient strategies for cartilage regeneration.…”
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4574
Implementing Large Language Models in Health Care: Clinician-Focused Review With Interactive Guideline
Published 2025-07-01“…General-purpose LLMs may not perform well in specialized areas as they often require lightweight prompt engineering methods or fine-tuning techniques based on specific datasets to improve model performance. …”
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4575
SFD-YOLO: A novel framework for subsidence funnels detection in China based on large-scale SAR interferograms
Published 2025-06-01“…Accurate identification of subsidence funnels is essential for assessing surface deformation in mining areas, preventing disasters, and optimizing resource management. However, recognizing subsidence funnels of varying sizes in large-scale interferograms poses significant challenges, particularly for small-sized funnels. …”
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4576
Borehole Optical Fibre Distributed Temperature Sensing vs. Manual Temperature Logging for Geothermal Condition Assessment: Results of the OptiSGE Project
Published 2024-11-01“…The presented research methods are suitable for applications connected with studies crucial to selecting the locations of geothermal installations and to optimize their technical parameters. …”
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4577
Cystic Artery Bleeding: Imaging Insights and Systematic Review of Endovascular Management
Published 2025-03-01“…Methods: This pictorial essay highlights key imaging findings in CAB and pseudoaneurysms, emphasizing the role of ultrasound, CT, and digital subtraction angiography (DSA) in diagnosis and management planning. …”
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4578
Comparative investigation of PFS and PAC coagulants with activated carbon in cellulose microfiltration systems for treatment of real printing ink wastewater
Published 2025-06-01“…In order to avoid these consequences, modern methods of treating printing ink wastewater (PIW)are needed, such as chemical precipitation, electrochemical advanced oxidation, and hybrid systems. …”
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4579
The role of molecular diagnostics in the choice of therapy for biliary tract cancers
Published 2024-03-01“…The aim of the study was to assess the frequency and clinical significance of various molecular genetic aberrations in biliary tract tumors and to determine the optimal methods of their testing. Material and Methods. …”
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4580
When politics meets policy: a realist review of how political context shapes the impact of public health legal interventions
Published 2025-08-01“…Future research should refine these insights using mixed-methods case studies and longitudinal evaluations, ensuring policy adaptations that optimize health equity and policy sustainability.…”
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