The Impact of Physical Activity on Clinical Outcomes in Children with Cystic Fibrosis: A Narrative Review by Chiara Rosolia Capasso, Antonio Luca Miniato, Paola Di Filippo, Armando Di Ludovico, Sabrina Di Pillo, Francesco Chiarelli, Giuseppe Francesco Sferrazza Papa, Marina Attanasi

“…Emerging evidence supports the role of physical exercise in improving lung function, aerobic capacity, and quality of life in pediatric CF patients. Methods: We reviewed randomized clinical trials and observational studies from the last ten years, sourced from PubMed and Google Scholar. …”
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Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection by Md. Rezaul Islam, Md. Ibrahim Khalil Al‐Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam, Mohammad Rakib Mortuza, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Kadirvel Devi, Tanuja Tummala, Mohammed Ali Alshehri, Kalirajan Rajagopal, Mohammed Asiri, Irfan Ahmad, Talha Bin Emran

“…Abstract Background Neurodegenerative diseases (NDs), including Alzheimer‘s disease, Parkinson‘s disease, and Huntington‘s disease, are complex and challenging due to their intricate pathophysiology and limited treatment options. Methods This review systematically sourced articles related to neurodegenerative diseases, neurodegeneration, quercetin, and clinical studies from primary medical databases, including Scopus, PubMed, and Web of Science. …”
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The therapeutic effect of antioxidant postbiotic cocktail in colitis mice: A promising approach to alleviate oxidative stress in two high-fat and normal-diet feeding mice by Niloofar Rezaie, Fahimeh Bagheri-Amiri, Shadi Aghamohammad, Shohreh Khatami, Malihe Talebi, Aria Sohrabi, Mohammad Reza Pourshafie, Mahdi Rohani

“…Therefore, in this study we aimed to assess the effectiveness of a novel postbiotic resulted from native probiotic Lactobacillus strains with robust antioxidant properties in ameliorating colitis in murine models fed with Normal-Diet or High Fat-Diet. Material and methods: Eighty-eight strains of Lactobacillus and Bifidobacterium sourced from human feces and milk were screened for antioxidant activity. …”
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Associations between Life’s Essential Eight cardiovascular health metrics and cardiovascular mortality risk across frailty statuses: evidence from a UK Biobank cohort study by Lirong Chai, Kai Zhang, Yi Zhang, Weijing Wang, Dongfeng Zhang, Junning Fan

“…Therefore, we aimed to assess the association between LE8 and CVD mortality among individuals with different frailty status.MethodsData were sourced from the UK Biobank of 439,462 participants aged 37–73 years. …”
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Comparative efficacy and safety in low-intensity treatment for acute myeloid leukemia in older patients: a systematic review and network meta-analysis by Wenze Li, Sijing Kang, Yu Jiao, Pengjie Yue, Weilin Dong, Rui Ge, Ziyi Wang, Xiaojing Yan

“…Despite the increasing number of randomized clinical trials (RCTs) and cohort studies in this area, the optimal treatment approach remains unclear. Methods We sourced four databases, PubMed, Embase, Cochrane, and Web of Science, until July 07, 2024, to identify all Phase II/III randomized controlled trials (RCTs) and cohort studies evaluating low-intensity treatments for older AML patients. …”
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Isokinetic Assessment of Knee Flexor and Extensor Strength and Lower Extremity Flexibility Assessment of an NCAA Division III Men’s Soccer Team by Savanna Perkins, Paul Canavan

“… # Study Design Observational cohort # Methods Standardized isokinetic testing of concentric muscle performance, measured by peak torque of the quadriceps and hamstrings and hamstring-to-quadriceps ratios, was conducted using a Biodex isokinetic dynamometer at speeds of 60 and 180°/sec. …”
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Recent advances in Polygonatum sibiricum polysaccharides: structural insights, bioactivities in Vitro and in Vivo, and therapeutic potential in human and animal models – A review by Mohamed E. Abd El-Hack, Hassan A. Rudayni, Ahmed K Aldhalmi, Abdullah S. Alawam, Ahmed A. Allam, Mohammad M.H. Khan, Asmaa F. Khafaga

“…Quantitative data from optimized conditions show PSP yields ranging from 4.4 % (hot water) to 29.7 % (NADES-based extraction). …”
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Harmonization trial on ESR1 testing strategies in ER+/HER2- breast cancer patients: an Italian experience by Francesco Pepe, Gianluca Russo, Konstantinos Venetis, Claudia Scimone, Lucia Palumbo, Mariantonia Nacchio, Domenica di Giovanni, Claudia Sarracino, Ilaria Tomaiuolo, Elisabetta Zulato, Matteo Fassan, Daniela Righi, Giuseppe Perrone, Dario de Biase, Gabriele Casati, Fabio Pagni, Lucia Gullotti, Antonio Rizzo, Alessandro Perez, Antonio Russo, Katia Zavaglia, Gianluca Gragnano, Domenico Cozzolino, Sabrina Alfano, Cristian Scatena, Sara D’andrea, Monica Schiappacassi, Giuseppina Roscigno, Alessia Paganotti, Renzo Boldorini, Francesco Esposito, Pierlorenzo Pallante, Daniela Furlan, Marta Sbaraglia, Angelo Paolo Dei Tos, Giancarlo Troncone, Nicola Fusco, Umberto Malapelle

“…Harmonized ring trials are key weapons to standardize analytical and post-analytical procedures optimizing clinical stratification of BC patients…”
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Advances in Traditional Chinese Medicine research in diabetic kidney disease treatment by Shiyi Shen, Huiyun Zhong, Xiaoshi Zhou, Guolin Li, Changji Zhang, Yulian Zhu, Yong Yang

“…Over recent decades, extensive research has explored the mechanisms of TCM for preventing and managing DKD, with substantial studies that endorse the therapeutic benefits of TCM compounds and single agents in the medical intervention of DKD.Objective This review lays the foundation for future evidence-based research efforts and provide a reference point for DKD investigation.Methods The relevant literature published in Chinese and English up to 30 June 2023, was sourced from PubMed, Cochrane Library, VIP Database for Chinese Technical Periodicals (VIP), Wanfang Data, CNKI, and China Biology Medicine disc (CBM). …”
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Economic evaluation of [18F]fluorocholine PET/CT in pre operative assessment of hyperfunctional parathyroids in primary hyperparathyroidism: a cost effectiveness analysis by Adel Mamou, Sihame Chkair, Olivier Gilly, Laurent Maimoun, Yassine Mamou, Sean C. Sheppard, Pierre Olivier Kotzki, Benjamin Lallemant, Vincent Boudousq

“…This study evaluates the cost-effectiveness of PET as a stand-alone first-line imaging strategy compared to CU + MIBI + PET and CU + PET strategies in the French healthcare system. Methods A Markov model estimated costs and quality-adjusted life years (QALYs) for each imaging strategy. …”
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The association between vitamin D intake and the prevalence and mortality of asthma in the US adults by Yu Lei, Yu Luo, Yi Wang, Caiyang Liu, Lei Luo, Ji Li

“…This study aims to clarify the relationship between vitamin D intake and asthma outcomes. Methods In this study, three logistic regression models were employed to investigate the association between vitamin D intake and the prevalence of asthma. …”
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Manufacturing Process Development for <i>Bison bison</i> Organ-Specific Lyophilized Extracts: Formulation and Benchmarking of Antioxidant Activities for Nutraceutical Preparations by Alexandre Porcello, Kim Girardet, Basste Hadjab, Kelly Lourenço, Corinne Scaletta, Philippe Abdel-Sayed, Nathalie Hirt-Burri, Lee Ann Applegate, Alexis E. Laurent

“…Lyophilized organ extracts from livestock such as beef or elk are widely commercially proposed as animal-sourced nutraceuticals. Such preparations contain blends of vitamins and nutrients that may be employed for general or specific dietary supplementation. …”
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Cost-effectiveness analysis of penpulimab plus carboplatin-paclitaxel as first-line treatment for metastatic squamous non-small-cell lung cancer in China by Luwei Wang, Jiasheng Chen, Lihui Lin, Xiaowei Huang

“…CP from the Chinese healthcare perspective. Methods A three-state Markov model was developed to evaluate the cost-effectiveness of PEN-CP as a first-line treatment for metastatic sqNSCLC. …”
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Are tailored primary care services for social inclusion good value for money? A health economics evaluation with Monte-Carlo probabilistic sensitivity analysis comparing tailored s... by Síle Kelly, Anne Dee, Patrick O’Donnell

“…The analysis compares cost outcomes between SEP who have access to a tailored SIPC service with those who do not. Methods A cost analysis of the part-time SIPC service, based on available Irish-sourced data on the usage and costs of acute care in the Health Service Executive (HSE), and a literature review were used to identify the cost and outcome parameters of the economic framework. …”
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WHO Framework Convention on Tobacco Control Articles 9 and 10 implementation for sustainable tobacco control—a scoping review protocol by Sonu Goel, Diksha Walia, Priyobrat Rajkhowa, Chirag Goel

“…This scoping review aims to explore the Implementation Landscape of WHO FCTC Articles 9 and 10 globally by adopting Consolidated Framework for Implementation Research (CFIR) framework. Methods The planned scoping review will adhere to the methodology outlined by “Arksey and O’Malley and Levac et al.” …”
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A real-world pharmacovigilance study of omalizumab using disproportionality analysis in the FDA adverse drug events reporting system database by Yongfu Song, Zhuang Wang, Na Wang, Xiaofei Xie, Tieshi Zhu, Yongji Wang

“…We assessed the significance of the association between omalizumab and adverse events using four distinct methods of disproportionality analysis. Furthermore, we analyzed adverse events across gender and age subgroups. …”
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Real-Time Detection of Forest Fires Using FireNet-CNN and Explainable AI Techniques by Gazi Mohammad Imdadul Alam, Naima Tasnia, Tapu Biswas, Md. Jakir Hossen, Sharia Arfin Tanim, Md Saef Ullah Miah

“…The model was evaluated using two augmented datasets: Dataset A and Dataset B, which consist of fire and non-fire images sourced from multiple video and image datasets. FireNet-CNN&#x2019;s architecture, which includes 2.75 million parameters and a compact model size of 10.58 MB, has been meticulously optimized for fire detection tasks. …”
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Evaluating the generalisability of region-naïve machine learning algorithms for the identification of epilepsy in low-resource settings. by Ioana Duta, Symon M Kariuki, Anthony K Ngugi, Angelina Kakooza Mwesige, Honorati Masanja, Daniel M Mwanga, Seth Owusu-Agyei, Ryan Wagner, J Helen Cross, Josemir W Sander, Charles R Newton, Arjune Sen, Gabriel Davis Jones

“…Here, we use a novel approach to assess the suitability and applicability of such clinical tools to aid screening and diagnosis of active convulsive epilepsy in settings beyond their original training contexts.<h4>Methods</h4>We sourced data from the Study of Epidemiology of Epilepsy in Demographic Sites dataset, which includes demographic information and clinical variables related to diagnosing epilepsy across five sub-Saharan African sites. …”
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Tumor ViT-GRU-XAI: Advanced Brain Tumor Diagnosis Framework: Vision Transformer and GRU Integration for Improved MRI Analysis: A Case Study of Egypt by Mohammed Aly, Abdullatif Ghallab, Islam S. Fathi

“…This combined model outperforms current diagnostic methods. Our framework was applied to primary MRI data sourced from the National Cancer Institute in Cairo, Egypt, and Brast2013/2015. …”
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Factors associated with the export of traditional Chinese medicinal products: A stochastic frontier analysis. by Ying Chen, Shuduo Zhou, Zhongfei Pei, Weili Zhao, Jian Yang, Yunxuan Hu, Xiangning Feng, Ming Xu

“…<h4>Methods</h4>We employed joinpoint regression analysis to examine the export value trend of traditional Chinese medicinal products from 2013 to 2022. …”
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