HERGAI: an artificial intelligence tool for structure-based prediction of hERG inhibitors by Viet-Khoa Tran-Nguyen, Ulrick Fineddie Randriharimanamizara, Olivier Taboureau

“…It also demonstrated superior screening power compared to virtual screening schemes that used existing scoring functions. This model, named “HERGAI,” along with relevant input/output data and user-friendly source code, is available in our GitHub repository ( https://github.com/vktrannguyen/HERGAI ) and can be used to predict drug-induced hERG blockade, even on large data sets.…”
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Clustering nuclear receptors in liver regeneration identifies candidate modulators of hepatocyte proliferation and hepatocarcinoma. by Michele Vacca, Simona D'Amore, Giusi Graziano, Andria D'Orazio, Marica Cariello, Vittoria Massafra, Lorena Salvatore, Nicola Martelli, Stefania Murzilli, Giuseppe Lo Sasso, Renato Mariani-Costantini, Antonio Moschetta

“…Nuclear receptors (NRs) are key players in the control of cellular functions, being ideal modulators of hepatic proliferation and carcinogenesis.…”
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Pathoadaptive Mutations of Escherichia coli K1 in Experimental Neonatal Systemic Infection. by Alex J McCarthy, David Negus, Patricia Martin, Catarina Pechincha, Eric Oswald, Richard A Stabler, Peter W Taylor

“…Only four single nucleotide polymorphisms (SNPs), in genes (gloB, yjgV, tdcE) or promoters (thrA) involved in metabolic functions, were found: no changes were detected in genes encoding virulence determinants associated with the invasive potential of E. coli K1. …”
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Comparative metabolomic profiling of Lupinus albus and L. angustifolius harvest residues: exploring chemical diversity and valorization potential by Salma Halime, Salma Halime, Jenny Renaut, Stéphanie Zimmer, Hanna Heidt, Cédric Jacquard, Kjell Sergeant

“…Lupin species are a rich source of bioactive compounds with diverse industrial applications, yet their harvest residues remain underutilized. …”
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A quantum inspired machine learning approach for multimodal Parkinson’s disease screening by Diya Vatsavai, Anya Iyer, Ashwin A. Nair

“…As disease progression impairs speech, memory, and motor functions over time, early diagnosis is crucial for preserving patients’ quality of life. …”
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Sunlight Noise Mitigation in FMCW LiDAR Using FADOF by Longfei Yin, Wei Tang, Ziwei Geng, Haodi Zhan, Lei Chen, Dasheng Qian, Guohua Wu, Bin Luo

“…Additionally, the system achieves a detection range of at least 17 meters under direct sunlight conditions. …”
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A metabolic profiling approach to characterize and discriminate plant-based beverages and milk by Gaia Meoni, Ingrid Sousa, Leonardo Tenori, Giovanni Niero, Marta Pozza, Massimo De Marchi, Carmen L. Manuelian

“…ABSTRACT: The rising demand for nondairy and nonanimal protein sources has increased plant-based beverages (PBB) consumption. …”
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Cost-Effective Photoacoustic Imaging Using High-Power Light-Emitting Diodes Driven by an Avalanche Oscillator by Alberto Prud’homme, Frederic Nabki

“…While lasers have traditionally been the light source for PAI, their high cost and complexity drive interest towards alternative sources like light-emitting diodes (LEDs). …”
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Two rare cases of severe community-acquired bloodstream infections: a clinical case report by Li-Na Meng, Gang Li

“…Detailed medical history inquiries, assessment of underlying immune status, detection of the source of infection, and initial precise identification and treatment of the infectious agents can improve the prognosis of CABSI.Case descriptionIn this paper, two incidences of severe CABSI with insidious onset and rapid progression are described. …”
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Severe pregnancy-associated atypical hemolytic uremia syndrome in the context of the COVID-19 pandemic: a novel survival case report by Yan Yang, Xiao-jin Li, Hua-Yan Yuan, Jing-Jing Xiong, Peng-Fei Li, Zhen Wang

“…Post-treatment evaluation showed normalized complement C3 and C4 levels, stabilized platelet and hemoglobin levels, and gradual normalization of liver function. Renal function improved gradually, and a bone marrow biopsy revealed no fragmented red blood cells. …”
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PhotoNeuro: A compact photodetector for synchronization of visual stimulus presentation during behavioural experiments in neuroscience by Xavier Cano-Ferrer, Marcelo J. Moglie, George Konstantinou, Antonin Blot, Gaia Bianchini, Albane Imbert, Petr Znamenskiy, M. Florencia Iacaruso

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The biomarker potential of circPOLD1 and its binding protein YBX1 in cervical carcinogenesis by Lu Zhao, Xin Chen, Yanan Zhang, Yixuan Cen, Tingjia Zhu, Lingfang Wang, Lili Xia, Yang Li, Xiaodong Cheng, Xing Xie, Weiguo Lu, Junfen Xu

“…Mechanistically, circPOLD1 functioned as an oncogene by binding to and phosphorylating YBX1, activating the AKT/mTOR/HIF-1α pathway to enhance glycolysis-driven tumorigenesis. …”
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Identification method of roof rock interface based on response characteristics of drilling parameters by LI Dianshang, LIU Cancan, WANG Chuanbing, REN Bo, REN Shuai, KANG Zhipeng

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Persistence of Reptile DNA in a Terrestrial Substrate: A Case Study Using the Eastern Indigo Snake by Leah R. N. Samuels, Houston C. Chandler, Michelle Hoffman, John A. Kronenberger, Michele Elmore, Robert Aldredge, Benjamin S. Stegenga, James E. Bogan Jr., Mark A. Davis, Stephanie Hertz, Michael K. Schwartz, Taylor Wilcox

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Study of Complex Impedance Dispersion Model for Two-Phase Laminar Flow by CHENG Linfeng, KE Shizhen, SHI Hongwei, ZHANG Yuhang, LUO Hu, TAO Jie

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Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons by Irika R. Sinha, Parker S. Sandal, Holly Spence, Grace D. Burns, Aswathy Peethambaran Mallika, Fatemeh Abbasinejad, Katherine E. Irwin, Anna Lourdes F. Cruz, Vania Wang, Shaelyn R. Marx, Josué Llamas Rodríguez, Ben Langmead, Jenna M. Gregory, Philip C. Wong, Jonathan P. Ling

“…We previously found that TDP-43 loss-of-function leads to transcriptome-wide inclusion of deleterious cryptic exons, a signature detected in presymptomatic biofluids and postmortem ALS-FTD brain tissue, but the upstream mechanisms that lead to TDP-43 dysregulation remain unclear. …”
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Probing Cosmic Isotropy with the FAST All Sky H i Survey by Yi-Wen Wu, Jun-Qing Xia

“…We do not detect any statistically significant deviations from cosmic isotropy in the FASHI survey data.…”
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Design and Development of an EMG Upper Limb Controlled Prosthesis: A Preliminary Approach by Ricardo Rodrigues, Daniel Miranda, Vitor Carvalho, Demétrio Matos

“…Preliminary results demonstrate reliable detection of muscle contractions (threshold = 7 ADC units, ~34 mV) and motor actuation with a response time of ~150 ms, offering a cost-effective alternative to commercial systems. …”
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Biomimicry as a decision-making methodology in condition monitoring by Hariom Dhungana

“…However, traditional condition monitoring techniques face several limitations: they rely heavily on high-quality, continuous sensor input, struggle with adaptability to new fault scenarios, require significant computational resources, and often provide limited decision support beyond fault detection. …”
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Accuracy of Vegetation Height and Terrain Elevation Derived from Terrestrial Ecosystem Carbon Inventory Satellite in Forested Areas by Zhao Chen, Sijie He, Anmin Fu

“…Forest ecosystems serve as pivotal components of the global carbon cycle, with canopy height representing a critical biophysical parameter for quantifying ecosystem functionality, thereby holding substantial implications for forest resource management and carbon sequestration assessments. …”
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