The Necessity of Prenatal Diagnosis by CMA for the Women with NIPS-Positive Results by Jun Xu, Ying Xue, Jing Wang, Qin Zhou, Bin Zhang, Bin Yu, Ting Wang

“…To retrospectively analyze the results of prenatal diagnoses of noninvasive prenatal screening- (NIPS) positive pregnant women and discuss whether there is a need for chromosomal microarray analysis (CMA). Methods. The study recruited 1,019 NIPS-positive women from two prenatal diagnostic centers. …”
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Cysteine‐rich intestinal protein 1 enhances the progression of hepatocellular carcinoma via Ras signaling by Hong‐Yu He, Li Hu

“…To further evaluate whether CRIP1 interacts with Ras, a specific siRNA targeting Ras was selected. We found that Ras knockdown reduced the activation of Ras/AKT signaling even in HepG2 cells transfected with CRIP1. …”
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Downregulation of sorting nexin 10 is associated with overexpression of miR-30d during liver cancer progression in rats by Nancy Cervantes-Anaya, Alberto Ponciano-Gómez, Guadalupe Soledad López-Álvarez, Christian Gonzalez-Reyes, Sergio Hernández-Garcia, María Asunción Cabañas-Cortes, José Efraín Garrido-Guerrero, Saúl Villa-Treviño

“…The identification of molecules that might be molecular markers or therapeutic targets is urgently needed to improve clinical management. Based on a microarray analysis performed in our laboratory, we selected six genes—namely, ANXA2, DYNLT1, PFKP, PLA2G7, KRT19 , and SNX10 —as candidates for validation as tumor markers of liver cancer in a rat model. …”
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A stratified transcriptomics analysis of polygenic fat and lean mouse adipose tissues identifies novel candidate obesity genes. by Nicholas M Morton, Yvonne B Nelson, Zoi Michailidou, Emma M Di Rollo, Lynne Ramage, Patrick W F Hadoke, Jonathan R Seckl, Lutz Bunger, Simon Horvat, Christopher J Kenyon, Donald R Dunbar

“…Using a stratified transcriptome gene enrichment approach we attempted to identify adipose tissue-specific obesity genes in the unique polygenic Fat (F) mouse strain generated by selective breeding over 60 generations for divergent adiposity from a comparator Lean (L) strain.…”
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Exploration of the shared pathways and common biomarkers in cervical and ovarian cancer using integrated bioinformatics analysis by Fang Liu, Min Wang, Tian Zhu, Cong Xu, Guangming Wang

“…Abstract Objective Searching for potential biomarkers and therapeutic targets for early diagnosis of gynecological tumors to improve patient survival. Methods Microarray datasets of cervical cancer (CC) and ovarian cancer (OC) were downloaded from the Gene Expression Omnibus (GEO) database, then, differential gene expression between cancerous and normal tissues in the datasets was analyzed. …”
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Metabolomic characterisation of the glioblastoma invasive margin reveals a region-specific signature by James Wood, Stuart J. Smith, Marcos Castellanos-Uribe, Anbarasu Lourdusamy, Sean T. May, David A. Barrett, Richard G. Grundy, Dong-Hyun Kim, Ruman Rahman

“…Here, we use liquid chromatography–mass spectrometry and gene expression microarray to profile integrated intratumour metabolic heterogeneity, as a direct functional readout of adaptive responses of subclones to the tumour microenvironment. …”
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Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia. by Ignat Drozdov, Bernhard Svejda, Bjorn I Gustafsson, Shrikant Mane, Roswitha Pfragner, Mark Kidd, Irvin M Modlin

“…High throughput techniques such as inference of gene regulatory networks from microarray experiments can objectively define signaling machinery in this disease. …”
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Combined Use of Gene Expression Modeling and siRNA Screening Identifies Genes and Pathways Which Enhance the Activity of Cisplatin When Added at No Effect Levels to Non-Small Cell... by Ada W Y Leung, Stacy S Hung, Ian Backstrom, Daniel Ricaurte, Brian Kwok, Steven Poon, Steven McKinney, Romulo Segovia, Jenna Rawji, Mohammed A Qadir, Samuel Aparicio, Peter C Stirling, Christian Steidl, Marcel B Bally

“…Being exposed to sub-lethal doses will induce changes in gene expression that contribute to the tumour cell's ability to survive and eventually contribute to the selective pressures leading to cisplatin resistance. …”
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HuoXueJieDu Formula Alleviates Diabetic Retinopathy in Rats by Inhibiting SOCS3-STAT3 and TIMP1-A2M Pathways by Hongliang Wang, Wei Xing, Shijie Tang, Zhenglin Wang, Tiantian Lv, Yan Wu, Shuzhen Guo, Chun Li, Jing Han, Ruixin Zhu, Wei Wang

“…Whole genome expression profiles in rat retinas were examined using microarray technology. Differential gene expression and pathway enrichment analysis were conducted on the microarray data, with validation through real-time PCR and immunohistochemical staining. …”
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ANALYSIS OF CELLULAR REACTION TO IFN-γ STIMULATION BY A SOFTWARE PACKAGE GeneExpressionAnalyser by A. V. Saetchnikov, M. M. Yatskou, P. V. Nazarov, L. Vallar, V. V. Apanasovich

“…The developed software has a number of advantages over the existing software: it is free, has a simple and intuitive graphical interface, allows to analyze different types of DNA microarrays, contains a set of methods for complete data analysis and performs effec-tive gene annotation for a selected list of genes.…”
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Enhancing Binary Classification Performance in Biomedical Datasets: Regularized ELM with SMOTE and Quantile Transforms Focused on Breast Cancer Analysis by Brilliant Friezka Aina, Meta Kallista, Ig. Prasetya Dwi Wibawa, Ginaldi Ari Nugroho, Ivana Meiska, Syifa Melinda Naf’an

“…Using microarray datasets, this research investigation addresses the problem of unbalanced data in binary classification tasks. …”
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DNA Methylation Profiles of Blood Cells Are Distinct between Early-Onset Obese and Control Individuals by Je-Keun Rhee, Jin-Hee Lee, Hae Kyung Yang, Tae-Min Kim, Kun-Ho Yoon

“…Here, we performed microarray-based DNA methylation and gene expression profiling of peripheral white blood cells obtained from six young, obese individuals and six healthy controls. …”
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miR-4780 Derived from N2-Like Neutrophil Exosome Aggravates Epithelial-Mesenchymal Transition and Angiogenesis in Colorectal Cancer by Liang Wang, Yuqiang Shan, Sixin Zheng, Jiangtao Li, Peng Cui

“…Differentially expressed miRNA in neutrophil exosomes have been sequenced by microarray profile, and the effect of N2-like neutrophil-derived exosomal miR-4780 on epithelial-mesenchymal transition (EMT) and angiogenesis was investigated. …”
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Fetal medicine and current practice of prenatal screening by Akshatha Prabhu

“…The fetal sample is used for various genetic tests, such as chromosome microarray analysis (CMA), targeted clinical exome sequencing (CES), or whole exome sequencing (WES) depending upon the abnormality noted or the suspected genetic condition. …”
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Antibiotic resistance in agroecosystem: Progress and challenges by ZHANG Yusen, YE Jun, SU Jianqiang

“…Both culture-dependent and culture-independent technologies, including metagenomic, microarray and high-throughput quantitative polymerase chain reaction have been utilized in the characterization of ARGs in agroecosystem, and each has its strength and weakness. …”
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Investigating Single-Molecule Molecular Inversion Probes for Medium-Scale Targeted DNA Methylation Analysis by Roy B. Simons, Hieab H. H. Adams, Manfred Kayser, Athina Vidaki

“…Considering CpGs with at least 20X coverage, we yielded robust methylation detection with levels comparable to those obtained from the gold standard EPIC microarray analysis (Pearsons’s r: 0.96). …”
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Bayesian weighted random forest for classification of high-dimensional genomics data by Oyebayo Ridwan Olaniran, Mohd Asrul A. Abdullah

“…The performance of the proposed method is analyzed using simulated and real-life high-dimensional microarray datasets based on holdout accuracy and misclassification error rates. …”
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Characterization of Human Knee and Chin Adipose-Derived Stromal Cells by Magali Kouidhi, Phi Villageois, Carine M. Mounier, Corinne Ménigot, Yves Rival, David Piwnica, Jérôme Aubert, Bérengère Chignon-Sicard, Christian Dani

“…Paired chin and knee fat depots were harvested from 11 subjects and gene expression profiles were determined by DNA microarray analyses. Adipose-derived stromal cells (ASCs) from both sites were isolated and analyzed for their capacity to proliferate, form clones, and differentiate. …”
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Genome-wide and rna-seq highlight genetic characteristics of rumpless signals in piao chicken by Wang Mei QI, Xing Fu ZHANG, Li Wen SONG, Zai Xia LIU, Yuan CHAI, Yan Yong SUN

“…Understanding the genetic relationship between rumpless chicken and other specific selection target breeds in the process of differentiation of the rumpless signal genes is helpful to reveal the genetic basis of rumplessnesss. …”
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Integrative Bioinformatics Analysis Unravel the Association between Intracerebral Hemorrhage and Cellular Apoptosis through Immune Infiltration by Pandi Chen, Gengfan Ye, Jia Li, Kuan Feng, Guangyao Zhu, Maosong Chen, Wei Chen

“…Key genes were identified through least absolute shrinkage and selection operator regression after model validation. …”
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