Bioinformatic Analysis of Apoptosis-Related Genes in Preeclampsia Using Public Transcriptomic and Single-Cell RNA Sequencing Datasets by Liu L, Li X, Yang H, Xu F, Dong X

“…When integrated into the diagnostic nomogram, they showed clinical utility and affected cell functions. In the immune profile of PE, monocytes decreased, resting NK cells increased, and the activities of APC, checkpoint, T-cell co-stimulation, and MHC class I pathways reduced. …”
Get full text

In-vitro transcriptomic profiling of indigenous Gaddi vis-à-vis exotic Labrador dogs: insights from systems biology by Jaswinder Kaur, Manu Mohan, Bilawal Singh, Ram Saran Sethi, Deepti Narang, Simarjeet Kaur, Chandra Sekhar Mukhopadhyay

“…Despite its vital role, it remains unrecognized by the National Bureau of Animal Genetic Resources (NBAGR). This study addresses the gaps in understanding the genetics and immune responses of Indigenous breeds, emphasizing their importance as holders of unique genetic heritage. …”
Get full text

Costs and Outcomes of a Therapist-Guided Internet-Delivered Cognitive Behavioral Therapy: Multicenter Observational Study by Zareen Abbas Khan, Jørn Heggelund, Stian Lydersen, Kristian Kidholm, Henrik Pedersen, Imre Janszky, Tine Nordgreen, Vidar Halsteinli

“…Regarding work and social functioning, 97 (33.0%) patients responded positively to the treatment and 60 (23.0%) achieved remission, as measured by the WSAS. …”
Get full text

Half-hourly electricity price prediction model with explainable-decomposition hybrid deep learning approach by Sujan Ghimire, Ravinesh C. Deo, Konstantin Hopf, Hangyue Liu, David Casillas-Pérez, Andreas Helwig, Salvin S. Prasad, Jorge Pérez-Aracil, Prabal Datta Barua, Sancho Salcedo-Sanz

“…Accurate prediction of electricity price (EP) is crucial for energy utilities and grid operators for enhancing the energy trading, grid stability studies, resource allocations and pricing strategies, thereby improving the overall grid reliability, efficiency, and cost-effectiveness. …”
Get full text

Improved detection of decreased glucose handling capacities via continuous glucose monitoring-derived indices by Hikaru Sugimoto, Ken-ichi Hironaka, Tomoaki Nakamura, Tomoko Yamada, Hiroshi Miura, Natsu Otowa-Suematsu, Masashi Fujii, Yushi Hirota, Kazuhiko Sakaguchi, Wataru Ogawa, Shinya Kuroda

“…This study assessed the utility of relatively easy-to-measure continuous glucose monitoring (CGM)-derived indices in estimating glucose handling capacities calculated from resource-intensive clamp tests. …”
Get full text

Comparison of feasibility and effectiveness of tunneled dialysis catheter placement with or without DSA guidance: a propensity score-matched cohort study by Yiwei Shang, Shujun Pan, Chen Jin, Danna Zheng, Xiujun Xu, Bin Zhu, Li Zhao, Juan Jin, Qiang He, Xiaogang Shen

“…Background In some resource-limited regions, the placement of tunneled dialysis catheters (TDC) is often preferred under ultrasound guidance rather than fluoroscopy. …”
Get full text

Design, Manufacture, and Performance Testing of a Water Hammer Pump with Five Different Air Chambers by Marco Fidel Romero Zárate, Héctor Flores-Breceda, Juan Arredondo-Valdez, Urbano Luna-Maldonado, Wilgince Apollon, Alejandro Isabel Luna-Maldonado

“…In Mexico, despite abundant overall water resources, many arid areas still lack access to reliable water. …”
Get full text

Extraction of degraded proteins from red and green macroalgae using ultrasonic-assisted extraction and Fenton's reagent in combination by Lin Ching I, Chang Chia Hsin, Fan Chih Hsuan, Chiu Pei Chia, Tsai Shu Hsien, Chien Chuan Chi, Lee Shih Chi, Chung Cheng Pei, Lee Ming Yi

“…This study utilized two common macroalgae species from Taiwanese waters, green algae Ulva lactuca (Ulva) and red algae Sarcodia suae (Sarcodia), to evaluate the feasibility and efficacy of a novel cell wall disruption technique combining Fenton reagent and ultrasound-assisted extraction (UAE). …”
Get full text

Machine learning-based model for acute asthma exacerbation detection using routine blood parameters by Youpeng Chen, Junquan Sun, Yabang Chen, Enzhong Li, Jiancai Lu, Huanhua Tang, Yifei Xie, Jiana Zhang, Lesi Peng, Haojie Wu, Zhangkai J. Cheng, Baoqing Sun

“…Background: Acute asthma exacerbations (AAEs) are a leading cause of asthma-related morbidity and mortality, especially in resource-limited settings where pulmonary function tests are unavailable or when patients are unable to cooperate with testing. …”
Get full text

A scRNA-seq reference contrasting living and early post-mortem human retina across diverse donor states by Luning Yang, Yiwen Tao, Qi Pan, Tengda Cai, Yunyan Ye, Jianhui Liu, Yang Zhou, Yongqing Shao, Quanyong Yi, Zen Huat Lu, Lie Chen, Gareth McKay, Richard Rankin, Weihua Meng

“…Conclusions Our atlas provides a single-cell reference contrasting living versus early postmortem human retina, integrating cell type composition, transcriptional diversity, and functional insights. It may serve as a useful resource for retinal research and for understanding aspects of human retinal biology, particularly given its inclusion of living tissue and diverse pathological states.…”
Get full text

Whole-Genome Resequencing Analysis of Copy Number Variations Associated with Athletic Performance in Grassland-Thoroughbred by Wenqi Ding, Wendian Gong, Tugeqin Bou, Lin Shi, Yanan Lin, Xiaoyuan Shi, Zheng Li, Huize Wu, Manglai Dugarjaviin, Dongyi Bai

“…Copy number variation (CNV) is an important source of genetic variation. However, studies utilizing whole-genome sequencing to investigate CNVs in horse populations and their effects on traits remain relatively limited. …”
Get full text

hnRNPA2B1 recognizes RNA virus SFTSV infection through mitochondrial DNA by Xin-bo Huang, Yue Zhang, Jing-wen Fan, Xin-yu Yu, Yun-lan Fang, Jin-xin Ren, Bin-yan Liu

Get full text

Novel Insights and Genomic Characterization of Coral-Associated Microorganisms from Maldives Displaying Antimicrobial, Antioxidant, and UV-Protectant Activities by Fortunato Palma Esposito, Andrea López-Mobilia, Michael Tangherlini, Vincenza Casella, Alessandro Coppola, Giulia Varola, Laura Vitale, Gerardo Della Sala, Pietro Tedesco, Simone Montano, Davide Seveso, Paolo Galli, Daniela Coppola, Donatella de Pascale, Christian Galasso

Get full text

The responses of vegetation water use efficiency to biomass density and CO2 balance in dryland of Central Asia during 21st century by Alphonse Kayiranga, Xi Chen, Xuexi Ma, Dative Ingabire, Tie Liu, Yaoming Li, Emeka Edwin Igboeli, Eldiiar Duulatov, Hubert Hirwa, Clement Nzabanita, Ping Hu

“…Water-use efficiency (WUE) is a critical component that links plant carbon (CO2) and water cycles through various aspects of plant ecosystem functioning. However, the variations of plant CO2 in response to water use efficiency (WUE) across temperate dryland ecosystems remains inadequately understood. …”
Get full text

Nanomaterials-assisted photothermal therapy for breast cancer: State-of-the-art advances and future perspectives by Sagnik Nag, Oishi Mitra, Garima Tripathi, Israrahmed Adur, Sourav Mohanto, Muskan Nama, Souvik Samanta, B.H. Jaswanth Gowda, Vetriselvan Subramaniyan, Vino Sundararajan, Vinoth Kumarasamy

“…Due to its spatial specificity and nominal invasive therapeutic regime, photothermal therapy (PTT) has attracted much scientific attention down the lane. PTT utilizes a near-infrared (NIR) light source to irradiate the tumor target intravenously or non-invasively, which is converted into heat energy over an optical fibre. …”
Get full text

Characterization of two novel chia (Salvia hispanica L.) white and black genotypes via DNA barcoding, physiological, and agronomic traits by Clara R. Azzam, Mokhtar Said Rizk, Soha Sayed Mohammad Mostafa, Ramadan A. Arafa, Mohamed Samy Al-Nabawi, Nahid Abdelaty Ali Morsi, Marwa Mahmoud Nasr El-Din, Enass Hassan Taher, Khaled Adly Khaled

“…Background: Chia (Salvia hispanica L.) is recognized for its nutritional value and health-promoting compounds, including flavonoids. Aim: This study utilized DNA barcoding to identify and differentiate two novel chia genotypes, CACH-W and CACH-B, providing insights for breeding programs and genetic resource conservation (CA refers to the developer and CH refer to Chia). …”
Get full text

An automated platform for simultaneous, longitudinal analysis of engineered neuromuscular tissues for applications in neurotoxin potency testing by Jacob W. Fleming, Molly C. McCloskey, Kevin Gray, David R. Nash, Vincent Leung, Christos Michas, Shawn M. Luttrell, Christopher Cavanaugh, Julie Mathieu, Shawn Mcguire, Mark Bothwell, David L. Mack, Nicholas A. Geisse, Alec S.T. Smith

“…Engineered models have emerged as alternatives for studying NMJ functionality in response to genetic and/or pharmacological challenge. …”
Get full text

Whole-Genome Sequencing and Fine Map Analysis of <i>Pholiota nameko</i> by Yan He, Bo Liu, Xiaoqi Ouyang, Mianyu He, Hongyan Hui, Bimei Tang, Liaoliao Feng, Min Ren, Guoliang Chen, Guangping Liu, Xiaolong He

“…This study aimed to address that gap by employing Illumina and Nanopore sequencing technologies to perform whole-genome sequencing, de novo assembly, and annotation analysis of the <i>P. nameko</i> ZZ1 strain. Utilizing bioinformatics methods, we conducted a comprehensive analysis of the genomic characteristics of this strain and successfully identified candidate genes associated with its mating type, carbohydrate-active enzymes, virulence factors, pan-genome, and drug resistance functions. …”
Get full text

Desain Layanan E-Surat untuk Desa Waru Barat, Pamekasan, Madura menggunakan QR-Code by Wahyudi Agustiono, Intan Rofika Putri, Devie Rosa Anamisa

“…Another flow-map evaluation also showed that the implementation of e-certificate was able to make the administrative process more streamlined, faster, remove geographical barrier, save the resources (cost, time and utility). Despite these practical implication, the contribution of this research, especially to the IT discipline which could be adopted in the future study, is the system architecture and e-certificate application along with the algorithm for generating unique QR Code to ensure the security and validity of the document.            …”
Get full text

Experimental evidence-based construction of electroacupuncture for ischemic stroke: a meta-analysis and systematic review by Yaoguang Guo, Sihan Hu, Sihan Hu, Shiman Luo, Lang Tu, Yao Tang, Fang Zeng, Fang Zeng, Fang Zeng

Get full text