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Osteoclast-independent osteocyte dendrite defects in mice bearing the osteogenesis imperfecta-causing Sp7 R342C mutation
Published 2025-07-01“…Remarkably, these defects in osteocyte function contrast to only mild changes in mature osteoblast function, suggesting that this Sp7 mutation selectively interferes with the function of Sp7 in osteocytes and mature osteoblasts, but not during early stages of osteoblast differentiation. …”
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2483
Time Series Remote Sensing Image Classification with a Data-Driven Active Deep Learning Approach
Published 2025-03-01“…Then, we define a new loss function with the aim of improving the deep model’s performance. …”
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2484
Incorporating Non-Coding Annotations into Rare Variant Analysis.
Published 2016-01-01“…<h4>Methods & results</h4>We conducted a candidate gene analysis using the UK10K sequence and lipids data, filtering according to functional annotations using the resource CADD (Combined Annotation-Dependent Depletion) and contrasting results with 'nonsynonymous' and 'loss of function' consequence analyses. …”
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2485
An innovative and mass-sensitive quartz tuning fork (QTF) biosensor for GFAP detection: A novel approach for traumatic brain injury diagnosis
Published 2025-08-01“…This biosensor is designed to facilitate the highly sensitive and selective detection of GFAP in human serum. In contrast to conventional neuroimaging methods, which are resource-intensive and frequently inaccessible in emergency situations, this innovative biosensor offers a portable, cost-effective, and efficient alternative for rapid GFAP measurement. …”
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2486
A dataset of expression profile of certain microRNAs in Caenorhabditis elegans
Published 2025-07-01“…The comprehensive dataset provided in this study will serve as a valuable resource for subsequent miRNA functional studies and candidate gene screening, thereby advancing our understanding of miRNA regulatory networks.…”
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2487
EEG signatures of cognitive and social development of preschool children-a systematic review.
Published 2021-01-01“…Studies reported on the domains of executive function (n = 22 papers), selective auditory attention (n = 9), learning and memory (n = 5), processing of faces (n = 7) and emotional stimuli (n = 8). …”
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2488
Ubiquitin-Specific Protease Inhibitors for Cancer Therapy: Recent Advances and Future Prospects
Published 2025-02-01“…Particular attention is given to the role of USP inhibitors in enhancing cancer immunotherapy, e.g., modulation of the tumor microenvironment, effect on regulatory T cell function, and influence on immune checkpoint pathways. …”
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2489
Simple Technology of Material Physics of Groundwater Conservation in Dealing with Climate Change in Disaster Areas of North Sumatera
Published 2023-09-01“…Water is a natural resource with a very important function for human life and advancing general welfare, so water is the basic capital and the main development factor. …”
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2490
Protocol Biopsies in Kidney Transplant Recipients: Current Practice After Much Discussion
Published 2025-07-01“…Despite the invasive nature and associated risks of biopsy procedures, most experts agree that the benefits outweigh the risks in selected populations. However, the role of routine protocol biopsies in low-risk patients remains debated due to unclear long-term outcome improvements and resource considerations. …”
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2491
Effects of upper-limb aerobic exercise plus general exercise versus general exercise alone among patients with spinal cord injury in northern Nigeria: A protocol for a randomized c...
Published 2025-01-01“…The outcome of this study could provide valuable guidance for rehabilitation professionals in selecting a low-cost and effective intervention for patients with SCI, particularly in resource-constrained settings.…”
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2492
Autophagy in aquatic animals: mechanisms, implications, and future directions
Published 2025-06-01Get full text
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2493
Evaluation and Optimization of Traditional Mountain Village Spatial Environment Performance Using Genetic and XGBoost Algorithms in the Early Design Stage—A Case Study in the Cold...
Published 2024-09-01“…As urbanization advances, rural construction and resource development in China encounter significant challenges, leading to the widespread adoption of standardized planning and design methods to manage increasing population pressure. …”
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2494
Simple Single-Person Fall Detection Model Using 3D Pose Estimation Mechanisms
Published 2024-01-01“…Our results show that SFDM outperforms selected other models in per-frame floating-point operations, achieving the lowest model complexity. …”
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2495
SpecDis: Value Added Distance Catalog for 4 Million Stars from DESI Year-1 Data
Published 2025-01-01“…To build up an unbiased training sample, we do not apply selections on parallax error or signal-to-noise (S/N) of the stellar spectra, and instead, we incorporate parallax error into the loss function. …”
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A telomere-to-telomere chromosome-scale genome assembly of glass catfish (Kryptopterus vitreolus)
Published 2025-03-01“…This high-quality T2T genome assembly not only provides a valuable genetic resource for investigating the molecular mechanisms underlying transparency, but also supports in-depth studies on functional genomics, genetic diversity, and selective breeding for this economically important fish species.…”
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A review on diagnostic assessments of tracheal stenosis
Published 2025-02-01“…It is a common complication after prolonged endotracheal intubation but may also arise from autoimmune or inflammatory processes. Clinicians can select the most appropriate treatment option based on individual patient conditions. …”
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Evaluating analytic strategies to obtain high-resolution, vertex-level measures of cortical neuroanatomy in children in low- and middle-income countries
Published 2025-06-01“…Abstract High-field magnetic resonance imaging to explore brain structure and function remains limited to high-resource settings. …”
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Adaptation of the modular number system in threshold secret sharing schemes
Published 2025-03-01“…The results of the presented work allow to conclude for modular threshold cryptosystems of secret sharing in distributed data processing systems that the use of a linear masking function and narrowing the range of changes in the masking analogue S̃ of the original secret S, allowing for minimally redundant coding for the selected p1, p2, …, pn, causes a significant reduction in the computational complexity of the calculated minimal-redundant modular arithmetic relations of integral characteristics within the framework of the model under study. …”
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