Viewing Global Changes in the Heliosheath with IMAP’s Energetic Neutral Atom Imagers by E. J. Zirnstein, J. Heerikhuisen, D. J. McComas, J. Bower, G. Clark, M. A. Dayeh, H. O. Funsten, M. Gkioulidou, D. G. Mitchell, D. B. Reisenfeld, N. A. Schwadron

“…We aim to answer the following: (i) What are the time delays as a function of energy and direction; (ii) at what energies can we observe changes the soonest; and (iii) what might the ENA source distributions affecting the time delays look like? …”
Get full text

Mid-infrared Ensemble Variability of Broad-line and Narrow-line Seyfert 1 Galaxies by Zhipeng Hu, Lisheng Mao

“…The MIR variability of the combined sample is positively correlated with black hole mass and the FWHM of the H β emission line at long rest-frame time lags. (4) The long-term MIR variability of the combined sample may be mainly driven by the Eddington ratio. (5) For BLSy1 galaxies, the MIR variability of radio-detected sources is greater than that of radio-undetected sources, whereas for NLSy1 galaxies, the opposite is true.…”
Get full text

A Spatial–Frequency Combined Transformer for Cloud Removal of Optical Remote Sensing Images by Fulian Zhao, Chenlong Ding, Xin Li, Runliang Xia, Caifeng Wu, Xin Lyu

Get full text

Generation of Cas9 Knock-In <i>Culex quinquefasciatus</i> Mosquito Cells by Elizabeth Walsh, Tran Zen B. Torres, Brian C. Prince, Claudia Rückert

“…In comparison to the RNAi-mediated gene silencing of <i>dicer-2</i>, <i>argonaute-2b</i>, and <i>piwi5</i>, our Cas9/sgRNA approach showed an enhanced ability to detect antiviral effects. <b>Conclusions</b>: We propose that this cell line offers a new tool for studying gene function in <i>Cx. quinquefasciatus</i> mosquitoes that avoids the use of RNAi. …”
Get full text

Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model by Samuel Martinez-Meza, Thomas A. Premeaux, Stefano M. Cirigliano, Courtney M. Friday, Stephanie Michael, Sonia Mediouni, Susana T. Valente, Lishomwa C. Ndhlovu, Howard A. Fine, Robert L. Furler O’Brien, Douglas F. Nixon

“…Although HIV-1 infected microglia were the initial source of pro-inflammatory cytokines, astrocytes, neurons and neural stem cells also had increased p-NF-kB levels, along with elevated CCL2 levels in the supernatant of HIV-1 M-BOs compared to Uninfected M-BOs. …”
Get full text

Expression and structural analysis of taste receptor genes in Iberian and Duroc pigs by Cristina Óvilo, Rita Benítez, Yolanda Núñez, Ramón Peiró-Pastor, Fabian García, Eduardo De Mercado, Emilio Gómez-Izquierdo, Juan García-Casco, Clemente López-Bote, María Muñoz

“…Gene expression was quantified in the circumvallate papillae of 48 growing Iberian and Duroc pigs maintained under identical management conditions but fed isocaloric diets differing in energy source: either high concentration of fat rich in oleic acid (HO) or carbohydrates (CH); and sacrificed after 47 days of treatment (50.5 kg live weight). …”
Get full text

Seismic fault identification method based on CBAM-TransUNet by Xin WANG, Wei ZHANG, Tongjun CHEN, Ao ZHANG, Dang ZHAO

Get full text

Association of Omega-3 Index and Blood Cell Count-Derived Systemic Inflammatory Indexes among Testicular Germ Cell Tumor Survivors by Milica Zeković, Marko Živković, Marija Takić, Sanja Stanković, Nebojša Bojanić, Aleksandar Janičić, Uroš Bumbaširević

“…Further large-scale research and long-term intervention trials are warranted to investigate the clinical significance of an increased intake of anti-inflammatory long-chain omega-3 polyunsaturated FA via dietary sources and/or supplementation in modulating the inflammatory process and reducing the morbidity burden in this patient population.…”
Get full text

Isolation and Characterization of L-Asparaginase-Producing Bacteria from the Arabian–Persian Gulf Region: First Report on <i>Bacillus xiamenensis</i> ASP-J1-4 as a Producer and Its... by Ghofran M. Al-Harbi, Essam Kotb, Abeer A. Almiman, Mahmoud M. Berekaa, Salwa Alhamad, Nada F. Alahmady, Meneerah A. Aljafary, Nadiyah M. Alqazlan, Reem I. Alyami, Joud M. Alqarni, Ebtesam Abdullah Al-Suhaimi

“…L-asparaginase (L-ASNase) functions as a chemotherapeutic enzyme with antitumor properties. …”
Get full text

Mutation of the histone demethylase Gasc1 causes ASD-like symptoms in mice by Tetsushi Kagawa, Yuhei Yamaguchi, Yasuhiro Kokubu, Genki Sudo, Aoi Ebisawa, Satoko Hattori, Keizo Takao, Kohtarou Konno, Naomi Nakagata, Takafumi Inoue, Masahiko Watanabe, Johji Inazawa, Tsuyoshi Miyakawa, Tetsuya Taga

Get full text

3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay by Di Wu, Xiaoqi Guan, Tao Yang, Jiashuai Yan, Biwen Zhu, Junchao Zhou, Yibing Guo, Yuhua Lu

“…Cancer stem cells (CSCs), the primary source of therapy resistance in pancreatic ductal adenocarcinoma (PDAC), exist in a dynamic equilibrium through tumor microenvironment (TME)-driven plasticity. …”
Get full text

HpFBH3 transactivates HpCO7 via binding to the E-boxes in the promoter and may accelerate flower formation in pitaya by Xiaowei Cai, Ling Xiao, Xiangmei Nie, Qiandong Hou, Sulin Wen, Kun Yang, Xiaopeng Wen

Get full text

Trends and advances in Leptospira, a bibliometric analysis by Wei Wang, Wei Wang, Wei Wang, Yamin Gao, Yamin Gao, Yamin Gao, Jianyu Ji, Jianyu Ji, Jianyu Ji, Zhai Huang, Zhai Huang, Bin Xiong, Bin Xiong, Shulin Xiang, Shulin Xiang

“…Prominent research areas included restriction endonucleases, monoclonal antibodies, outer membrane proteins, water environments, detection methods, and antimicrobial agents. Research focus has shifted from early genomic and antigenic studies to investigations into outer membrane protein functions and environmental persistence, culminating in recent advances in molecular mechanisms and diagnostic technology development.ConclusionThis bibliometric analysis provides a comprehensive snapshot of leptospirosis research, emphasizing collaborations and impact among authors, countries, institutions, and journals. …”
Get full text

Genotype × environment interaction analysis and climatic factors impacts on grain yield in rainfed durum wheat trials in Iran by Reza Mohammadi, Moslem Abdipour, Mahnaz Rahmati, Mohammad Armion, Nastaran Mehri, Asghar Mehraban

Get full text

Influence of Organic Nitrogen Derived from Recycled Wine Lees and Inorganic Nitrogen on the Chemical Composition of Cabernet Sauvignon Wines Fermented in the Presence of Non-Saccha... by Claudia López-Lira, Pedro Valencia, Alejandra Urtubia, Esteban Landaeta, Ricardo A. Tapia, Wendy Franco

“…In this study, the influences of inorganic nitrogen source (INS) and organic nitrogen source (ONS) supplementation during the wine fermentation process using three non-Saccharomyces yeasts (<i>Candida zemplinina</i>, <i>Candida oleophila</i>, and <i>Candida boidinii</i>) were analyzed. …”
Get full text

Genome-wide identification and analysis of SmRR gene family in eggplant (Solanum melongena L.) and their response to abiotic stress and auxin by Wenjing Li, Hui Li, Yanyu Lin, Yutong Li, Xiaofang Xie, Xuefang Zheng, Weiren Wu, Yuanchang Zhou, Yan Zheng

Get full text

LIFE CYCLE ASSESSMENT IN HEALTHCARE SYSTEM OPTIMIZATION. INTRODUCTION by V. Sarancha, K. Vitale, S. Oreskovic, V. Sulyma

“…Various factors and parameters that may influence effectiveness of different sectors in healthcare system are detected. Performance optimization of detected parameters could lead to better system functioning, higher patient safety, economic sustainability and reduce resources consumption.…”
Get full text

Dietary Jerusalem artichoke polysaccharide supplementation alters the growth performance, ruminal microbes and metabolites, muscle fatty acid and amino acid profiles in fattening l... by Cuihua Guo, Dongmei Ma, Chongyu Zhang, Yunpeng Wang, Farman Ullah, Xiaojun Wang, Yunkyoung Lee, Guiguo Zhang

Get full text

Epidemiology of Disability of Adult Population in the Russian Federation by S. N. Puzin, M. A. Shurgaya, N. V. Dmitrieva, G. E. Pogosyan, I. V. Lyalina, A. M. Mammaraeva, T. A. Ivanova, L. S. Idrisova

“…In one elderly patient older than 60 years, on average, four to five different chronic diseases are detected. The accumulation of impaired functions of organs and systems helps to reduce the adaptive capacity of the body and is associated with limited life, which entails an increase in the risks of disability in the elderly and the need for medical and social rehabilitation. …”
Get full text

Estimating fish stock biomass using a Bayesian state-space model: accounting for catchability change due to technological progress by Makoto Nishimoto, Yoshinori Aoki, Naoto Matsubara, Paul Hamer, Yuichi Tsuda

“…This model allows for the flexible integration of the timing and functional form of the uptake of technological innovations that are assumed to influence catchability. …”
Get full text