Mortalin overexpression predicts poor prognosis in early stage of non–small cell lung cancer by Jie Sun, Shuan-Long Che, Jun-Jie Piao, Ming Xu, Li-Yan Chen, Zhen-Hua Lin

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HBXIP suppression reduces cell proliferation and migration and its overexpression predicts poor prognosis in non-small-cell lung cancer by Yixuan Wang, Nan Li, Shuanlong Che, Tiefeng Jin, Junjie Piao, Shuangping Liu, Zhenhua Lin

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Proteomic analysis of plasma unravels dynamic pathways and potential biomarkers indicating disease stages following Mtb infection by Zonglei Zhou, Jie Tian, Yuying He, Haiyan Xiong, Weibing Wang

“…ABSTRACT Tuberculosis (TB) stages depend greatly on the interaction between Mycobacterium tuberculosis (Mtb) and the host response. As a non-negligible source of active tuberculosis (ATB), individuals with latent Mtb infection (LTBI) are insidious and hard to be detected due to limited biomarkers. …”
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Semantic distances of WAIS Similarities word pairs in non-demented adults: An item-level index of semantic memory granularity by Matteo De Marco, Satyam Chauhan, Martina Bocchetta, Annalena Venneri

“…LCH is a valuable construct that could help clinicians detect semantic memory decline in ageing adults with suspected neurodegeneration.…”
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Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bov... by Leonie Seemann, Susanne Kersten, Susanne Bühler, Fabian Billenkamp, Ulrich Meyer, Christian Visscher, Korinna Huber, Erika Most, Klaus Eder, Sven Dänicke, Jana Frahm

“…Fatty acids, among other substrates, are utilized by immune cells as an energy source. Therefore, L-carnitine, which is authorized as a feed additive in cattle, may influence the metabolism of peripheral blood mononuclear cells (PBMC) during an immune challenge. …”
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Genomic Signatures of Positive Selection and Local Adaptation in Ethiopian Sheep Populations by B. E. Demissie, G. M. Tarekegn, H. Dadi, Z. Edea, A. A. Woldesemayat, K-S Kim, S. Girma, T. Seyoum, K. Melaku, S. Keskes

“…Fixation index (FST) and cross-population extended haplotype homozygosity (XPEHH) methods were used to detect signatures of positive selection. Functional analysis revealed genes related to plateau adaptation, immune response, and tail fat formation. …”
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Discontinuation of immune checkpoint inhibitors for reasons other than disease progression and the impact on relapse and survival of advanced melanoma patients. A systematic review... by Konstantinos Lallas, Eftychia Chatziioannou, Derya Durak, Georg Frey, Lina Maria Serna-Higuita, Marie-Lena Rasch, Athanassios Kyrgidis, Eleni Timotheadou, Zoe Apalla, Ulrike Leiter, Lukas Flatz, Lukas Flatz, Aimilios Lallas, Teresa Amaral, Teresa Amaral

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Klebsiella pneumoniae under xylose pressure: the growth adaptation, antimicrobial susceptibility, global proteomics analysis and role of XylA and XylB proteins by Ruolan Yi, Jiaoyang Zheng, Zhichao Xu, Jiayan Wu, Fangfang Liu, Jinxin Zheng, Duoyun Li, Shiqing Han, Zhijian Yu

“…Additionally, while the growth adaptation of K2044−8Xyl−60G under xylose pressure was confirmed, no amino acid mutations were detected in the functional proteins of this xylose-induced isolate, suggesting that persistent xylose pressure does not cause nonsense mutations in the bacterial genome. …”
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Chromosome-level genome assembly of starry flounder (Platichthys stellatus) by Weiwei Zheng, Changlin Liu, Shenglei Han, Tengteng Wang, Tao Yang, Zhihong Liu, Dong Xu, Huizong Han, Xiaoqing Xi, Changwei Shao, Kaiqiang Liu

“…Approximately 94.02% of assembled sequences were anchored into 24 pseudochromosomes, and a total of 18 telomeres were detected. Totally 22,835 protein-coding genes and 227.87 Mb repetitive sequences were identified. …”
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Genetic Basis and Exploration of Major Expressed QTL <i>qLA2-3</i> Underlying Leaf Angle in Maize by Yonghui He, Chenxi Wang, Xueyou Hu, Youle Han, Feng Lu, Huanhuan Liu, Xuecai Zhang, Zhitong Yin

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Chromosome-scale genome assembly and annotation of two geographically distinct strains of malaria vector Anopheles albimanus by Dieunel Derilus, Gareth D. Weedall, Michael W. Vandewege, Dhwani Batra, Mili Sheth, Lori A. Rowe, Ananias A. Escalante, Audrey Lenhart, Lucy Mackenzie Impoinvil

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Unraveling Fish Community Diversity and Structure in the Yellow Sea: Evidence from Environmental DNA Metabarcoding and Bottom Trawling by Jinyong Zhang, Xiaoyu Cui, Lin Lin, Yuan Liu, Jinqing Ye, Weiyue Zhang, Hongjun Li

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Characteristics of Land Use Change and Evaluation of Ecological Sensitivity in Chongqing by XIE Xianjian, GOU Qiantao, WU Han

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Rapid parameter estimation for merging massive black hole binaries using continuous normalizing flows by Bo Liang, Minghui Du, He Wang, Yuxiang Xu, Chang Liu, Xiaotong Wei, Peng Xu, Li-e Qiang, Ziren Luo

“…The fast and accurate parameter estimation of merging MBHBs is of great significance for the global fitting of all resolvable sources, as well as the astrophysical interpretation of gravitational wave signals. …”
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Sarcopenia diagnosis using skeleton-based gait sequence and foot-pressure image datasets by Muhammad Tahir Naseem, Na-Hyun Kim, Haneol Seo, JaeMok Lee, Chul-Min Chung, Sunghoon Shin, Chan-Su Lee

“…IntroductionSarcopenia is a common age-related disease, defined as a decrease in muscle strength and function owing to reduced skeletal muscle. One way to diagnose sarcopenia is through gait analysis and foot-pressure imaging.Motivation and research gapWe collected our own multimodal dataset from 100 subjects, consisting of both foot-pressure and skeleton data with real patients, which provides a unique resource for future studies aimed at more comprehensive analyses. …”
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Diverse ancestral representation improves genetic intolerance metrics by Alexander L. Han, Chloe F. Sands, Dorota Matelska, Jessica C. Butts, Vida Ravanmehr, Fengyuan Hu, Esmeralda Villavicencio Gonzalez, Nicholas Katsanis, Carlos D. Bustamante, Quanli Wang, Slavé Petrovski, Dimitrios Vitsios, Ryan S. Dhindsa

“…These findings highlight the need for enhanced population representation in genomic resources to fully realize the potential of precision medicine and drug discovery. …”
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Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation by Jingyi Hou, Jingyi Hou, Jingyi Hou, Lihan Wang, Lihan Wang, Naiqiang Zhu, Xueli Li

“…This study aimed to clarify the roles of mitochondrial metabolism and immune infiltration in MI, using a combination of bioinformatics analyses and experimental validation.MethodsMI chip data (GSE96561, GSE181872, and GSE183272) were obtained from the Gene Expression Omnibus (GEO) database, and mitochondrial gene data were sourced from the MitoCarta3.0 database. Differentially expressed genes (DEGs) were identified and subjected to functional enrichment analyses. …”
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ESSegNeXt: A Novel Building Extraction Framework Based on Generalized SamGeo and SegNeXt Models Using High-Resolution Remote Sensing Images by Qi Lu, Wensong Liu, Lianpeng Zhang, Erzhu Li, Junlong Qiu, Lei Wang

“…Additionally, an edge-preserving loss function was introduced to enhance the boundary detection capability of the SegNeXt model using edge features extracted by SamGeo during cyclic validation. …”
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DistB-Condo: Distributed Blockchain-Based IoT-SDN Model for Smart Condominium by Anichur Rahman, Md. Jahidul Islam, Ziaur Rahman, Md. Mahfuz Reza, Adnan Anwar, M. A. Parvez Mahmud, Mostofa Kamal Nasir, Rafidah Md. Noor

“…Condominium network refers to intra-organization networks, where smart buildings or apartments are connected and share resources over the network. Secured communication platform or channel has been highlighted as a key requirement for a reliable condominium which can be ensured by the utilization of the advanced techniques and platforms like Software-Defined Network (SDN), Network Function Virtualization (NFV) and Blockchain (BC). …”
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Composition of the culturable bacterial community associated with the water column and soft tissues from oysters of the mangrove ecosystem at Honda Swamp, Colombian Caribbean by Lersy López Gutiérrez, Martha Torres, Esteban Zarza González, Alejandro Henao Castro, Laura Contreras Vega

“…Microbiological activity is the basis of ecosystems functioning, among these are the mangroves, which offer a wide variety of goods and services to humanity. …”
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