Insights on comprehensive characterization of distinct growth stages of Sterculia foetida pod as a potential feedstock for bioethanol production by Saroja Pasupathi, Sameeha Syed Abdul Rahman, Sugumaran Karuppiah

“…Abstract Lignocellulosic biomass explores a sustainable and renewable energy source that could provide a suitable solution to energy demands. …”
Get full text

A Regional Reduction in Ito and IKACh in the Murine Posterior Left Atrial Myocardium Is Associated with Action Potential Prolongation and Increased Ectopic Activity. by Andrew P Holmes, Ting Y Yu, Samantha Tull, Fahima Syeda, Stefan M Kuhlmann, Sian-Marie O'Brien, Pushpa Patel, Keith L Brain, Davor Pavlovic, Nigel A Brown, Larissa Fabritz, Paulus Kirchhof

“…<h4>Methods</h4>We used high-resolution optical mapping and sharp microelectrode recordings to quantify regional differences in electrical activation and repolarisation within the intact, superfused murine left atrium and quantified regional ion channel mRNA expression by Taqman Low Density Array. We also performed selected cellular electrophysiology experiments to validate regional differences in ion channel function.…”
Get full text

Chi-circ_0009659 modulates goat intramuscular adipocyte differentiation through miR-3431-5p/STEAP4 axis by Xin Li, Hao Zhang, Yong Wang, Yanyan Li, Youli Wang, Yan Xiong, Wei Liu, Yaqiu Lin

Get full text

Biased thalamic innervation onto the distinct subregion where dopamine receptor 1 is dominantly expressed in the caudal striatum by Fuko Kadono, Jingqi Wang, Kenta Kobayashi, Fuyuki Karube, Fumino Fujiyama

“…Retrograde tracer labeling identified potential sources of subcortical glutamatergic projections. …”
Get full text

INFORMATION TECHNOLOGY FOR THE INTEGRATED ASSESSMENT OF EXPERT COMPETENCY by Olena Lobach, Igor Babych, Elena Persiyanova

“…The following results were obtained: the problem of assessing the quality of experts was considered; based on the authors’ practical experience and analysis of literature sources, the structural diagram of the properties of experts and their assessment was developed; five main groups of existing methods for assessing the quality of experts were analyzed; existing models of an integrated assessment of the competency of experts were reviewed; a two-stage method for the integrated assessment of the competency of experts was developed by integrating the methods of heuristic, test, and statistical assessment; the main groups of users and functional requirements to the information system for assessing the competency of experts were identified; the database and user interface of the information system were developed; the developed information technology of the integrated assessment of the competency of experts was tested on actual data for selecting an expert group to choose the methodology of project management. …”
Get full text

A Systematic Review and Meta-analysis of Scrub Typhus and its Association with Liver Disease by Shalini Balamurugan, Reenaa Mohan, Jenifer Florence Mary, Kulkarni Sweta, Tresa Remya Athipozhi Thomas, Saranya Selvamurthy, Sanjay Pasupathy

“…The studies selected were all scrub typhus patients associated with liver diseases. …”
Get full text

Carbon Dioxide Storage Site Location and Transport Assignment Optimization for Sustainable Maritime Transport by Yanmeng Tao, Ying Yang, Yuquan Du, Shuaian Wang

“…Maritime carbon dioxide (CO₂) transport plays a pivotal role in facilitating carbon capture and storage (CCS) systems by connecting emission sources with appropriate storage sites. This process often incurs significant transportation costs, which must be carefully balanced against penalties for untransported CO₂ resulting from cost-driven decisions. …”
Get full text

Integrating brain proteomes and genetics to identify novel risk genes in chronic widespread musculoskeletal pain by Zhisen Dai, Yanlin Wu, Huaqing Huang, Huizhe Zheng

“…By combining high-throughput data from multiple sources, we integrated proteome-wide association studies (PWAS), transcriptome-wide association studies (TWAS), summary-based Mendelian randomization (SMR), and Bayesian co-localization analyses. …”
Get full text

Sunflower-based butterfly optimization algorithm with enhanced RNN for the harmonics elimination in multilevel inverter by V. Mohan, G. Krithiga, M. Thamil Alagan, V. Sathya

“…The fundamental goal of Multi Level Inverters (MLIs) is to produce an approximate sinusoidal voltage from many levels of dc voltages, which are typically supplied from capacitor voltage sources that convert DC input voltage to AC output voltage. …”
Get full text

Effects of climate change on goat production and mitigatory measures in semiarid savanna ecosystems by Alban Mugoti, Casper Nyamukanza, Anderson Munengwa, Sizo Moyo, Nation Chikumba

“…Additionally, studies highlight the effectiveness of improved animal husbandry techniques, including strategic water resource management and diversified feed sources, in enhancing goat health and productivity under changing environmental conditions. …”
Get full text

The Digital Transformation of Tafsir and Its Implications for Islamic Legal Derivation in the Contemporary Era by Ali Sati, Abdul Halim, Abdul Hayy Nasution, Muhammad Ridwan

“…Utilizing a qualitative literature review combined with thematic content analysis, this research draws on classical sources and contemporary scholarship to investigate the shifting landscape of Islamic legal derivation in the digital age. …”
Get full text

Effect of Different Synthetic Nitrogen Forms and Levels on Nitrification and Denitrification Key Genes Abundances: Implications for Oligotrophic Forest Soil Management by Muhammad Jamal Ameer, Yushan Liu, Xiaoting Zhao, Siyu Yan, Tongbao Qu

“…Similarly, NO₃⁻ infiltrates and contaminated drinking water sources lead to human thyroid dysfunction. In order to protect depleting timber growth due to nitrogen deficiency and increasing ecological concerns from nitrogen misapplication, we reviewed the effects of different synthetic nitrogen forms and levels on the biogeochemical process. …”
Get full text

Intensive Care for Acute Liver Failure in Pediatric Practice (Review) by G. A. Avakyan, Yu. V. Bykov, A. N. Obedin

“…Anesthesiologists and intensivists face significant challenges in the diagnosis and prevention of ALF.The aim of this review is to analyze the main triggers, etiology, pathogenesis, clinical manifestations and both specific and supportive treatment approaches for ALF in pediatric intensive care units.The Cochrane Library, PubMed, Medscape and Library.ru databases were used to conduct a systematic search and analysis of the scientific literature using the keywords «acute liver failure, children and adolescents, hepatic encephalopathy, cerebral edema, extracorporeal methods, liver transplantation». A total of 81 sources were selected for review. Inclusion criteria were studies that described the pathogenesis, clinical manifestations, diagnosis and treatment of ALF in the pediatric intensive care unit. …”
Get full text

The Challenges of Safety Culture: No more risk! by Julija Melnikova

“…These factors by themselves are the definite source of disaster. People are not able to avoid their impacts: different crashes, accidents, fires. …”
Get full text

Mito Stress Assay of PBMCs With Seahorse XFe96 Flux Analyzer and Comparison of Poly-D-Lysine and Poly-L-Lysine for Cell Affinity by Kumudu Subasinghe, R. Berry III, Megan Rowe, Ali Winters, Shaohua Yang, Nicole Phillips

“…Recent studies have suggested that these cell populations provide an overview of systemic changes within the body and therefore provide a source of sensitive biomarkers. Assessing mitochondrial function in PBMCs has been shown to provide an indication of metabolic stress associated with diseases such as diabetes and neurodegenerative conditions such as Alzheimer’s disease. …”
Get full text

Targeting GJB4 to inhibit tumor growth and induce ferroptosis in pancreatic cancer by Xiangru Zheng, Wenjun Li, Xiaoli Li, Qianyi Yao, Luquan Zheng, Rongrong Fan, Ping Bie

“…Bioinformatics analysis was conducted to explore the function of GJB4 in PC cells. Changes in ferroptosis in PC cells following GJB4 downregulation were detected by immunofluorescence staining, transmission electron microscopy, and western blotting.ResultsGJB4 expression was found to be upregulated in PC tissues and positively correlated with patient survival. …”
Get full text

Characterization of multi-targeted insulin-mimetic antidiabetic peptides using in silico approaches. by Anas Bilal, Ghulam Mustafa

“…The aim of the current study was to develop hypoglycemic peptides (HGPs) from plant sources and to investigate their binding interactions with selected diabetic protein receptors using peptide-protein docking, in order to identify potential peptide candidates for the treatment of diabetes mellitus. …”
Get full text

Unravelling the Impact of an Additional Sex Chromosome in an Adult Female by Sigin George, Vikas Dagar, Barun Kumar Chakrabarty, N. Nagaraja

“…Chromosomal microarray, which is a more expensive test, substantiated the presence of additional X chromosomes but failed to detect the presence of low level of mosaicism. Our case study emphasised the recommendation of performing a strategy-based cost-effective cytogenetic evaluation of all cases of decreased ovarian reserve or low anti-Müllerian hormone levels in a resource-constrained setting. …”
Get full text

A bibliometric and visual analysis of Jak1 to explore trends and frontiers by Cong Yu, Jiamin Cao, Xiaodong Xie, Wenguang Chen, Ensi Hong, Ensi Hong

“…Consequently, JAK1 has garnered significant attention in recent years.MethodsWe use bibliometric and visual analysis to evaluate the thematic trends and knowledge structure of TRPV1’s research papers on JAK1, sourced from the Web of Science core collection from 2003 to 2024. …”
Get full text

Advancing Predictive Healthcare: A Systematic Review of Transformer Models in Electronic Health Records by Azza Mohamed, Reem AlAleeli, Khaled Shaalan

“…Notably, case studies demonstrated a 30% boost in entity recognition accuracy in clinical notes and a 90% detection rate for malignancies in medical imaging. …”
Get full text