Predictive model for coronavirus disease 2019 severity based on blood biomarkers: a retrospective study by Liu Xiaoyan, Bao Zhongying, Duan Shuhong, Sun Jing, Zhang Yijie, Zhang Jie, Liu Jingxin

“…Emergency department data functioned as an independent external validation set to test the model’s generalizability.ResultsThe study included 1,007 patients, with 778 in the training set and 229 in the validation set. …”
Get full text

Synthesis of aluminum oxide nanoparticles using seeds of Carica papaya and evaluation of it for antimicrobial, antioxidant, and photocatalysis activity by Indrani Laskar, Rajib Saha

“…The presence of an absorption peak at a wavelength of 272 nm in the synthesized nanoparticles was detected by UV–Vis spectroscopy analysis. The results of the FTIR study confirmed the existence of various chemicals and functional groups in the 500–4000 cm−1 range. …”
Get full text

A Validation Tool (VaPCE) for Postcoordinated SNOMED CT Expressions: Development and Usability Study by Tessa Ohlsen, Viola Hofer, Josef Ingenerf

“…When errors are detected, the tool processes the SNOMED CT Concept Model in JSON format and applies predefined error categories. …”
Get full text

Preliminary exploration of mRNA, lncRNA, and miRNA expressions in the bovine jejunum unveils novel aspects of Mycobacterium avium subspecies paratuberculosis infections by Yahui Gao, Jie Cao, Bo Han, Dongxiao Sun

“…This study provided a valuable resource for understanding the molecular basis of JD, potentially contributing to the genetic improvement of JD resistance in dairy cattle.…”
Get full text

CGREF1 modulates osteosarcoma proliferation by regulating the cell cycle through the Wnt/β-catenin signaling pathway by Zicheng Wei, Kezhou Xia, Wenda Liu, Xinghan Huang, Zhun Wei, Weichun Guo

“…Methods Tumor Immune Estimation Resource (TIMER), The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases were utilized for bioinformatics analysis. …”
Get full text

Statistics on the Industry Structure of the Russian Economy and its Optimization Model by O. V. Morozov, M. A. Vasiliev

“…Optimization of the scale of industries is the formation of structural conditions for a more efficient functioning of the Russian economy; it can be recognized as a macroeconomic condition and a strategic reserve for the economic growth.…”
Get full text

High prevalence of fecal carriage of extended-spectrum beta-lactamase producing Enterobacterales among patients with urinary tract infections in rural Tanzania by Magreth Erick Macha, Magreth Erick Macha, Magreth Erick Macha, Weihong Qi, Salome N. Seiffert, Anja Bösch, Philipp Kohler, Honorathy Msami Urassa, Sabine Haller, Erin West, Maja Weisser Rohacek, Maja Weisser Rohacek, Maja Weisser Rohacek, Baharak Babouee Flury, Baharak Babouee Flury, Baharak Babouee Flury, Baharak Babouee Flury

Get full text

Trade-offs and synergies for urban Production-Living-Ecological spatial Patterns-Comparison study between Fuzhou, China, and Saskatoon, Canada by Xi Wang, Xiaomei Li, Jinming Sha, Hao Zhang, Eshetu Shifaw, Xulin Guo, Shuhui Lai, Jinliang Wang

Get full text

A pan-cancer analysis of the prognostic and immunological roles of zinc finger protein 514 in human tumors by Shuai Zhao, Shuai Zhao, Shuai Zhao, Lin Cheng, Xingzhao Ji, Xingzhao Ji, Shengnan Sun, Shengnan Sun, Shengnan Sun, Yi Liu, Yi Liu, Qiang Wan, Qiang Wan, Qiang Wan

“…We also used the Tumor Immune Estimation Resource 2.0 (TIMER 2.0) database to investigate the association between ZNF514 expression and immune checkpoint genes and immune infiltration. …”
Get full text

Smart diabetes management: remote monitoring and predictive health insights by K.S. Smelyakov, I.A. Lurin, K.V. Misiura, A.S. Chupryna, T.V. Tyzhnenko, O.D. Dolhanenko, V.M. Repikhov

“…It supports offline functionality for rural or under-resourced areas, and offers intuitive dashboards for patients and healthcare providers, boosting engagement and treatment adherence. …”
Get full text

WHSC1/NSD2 regulates immune infiltration in prostate cancer by Kunle Odunsi, Junko Matsuzaki, Takemasa Tsuji, Sebastiano Battaglia, Richard C. Koya, Prashant K Singh, Muzamil Y Want, James L Thorne, Ellen Karasik, Bryan Gillard, Eduardo Cortes Gomez, Amit Lugade

Get full text

Multimodal versus non-contrast computed tomography for assessment of acute ischaemic stroke: the PRACTISE RCT by Keith W Muir, Salwa El Tawil, Alex McConnachie, Alicia Murray, Ian Ford, Grant Mair, Joanna Wardlaw

“…Treatment decision and delivery times, early neurological recovery and day 90 functional outcomes did not differ significantly between groups. …”
Get full text

Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Key outcomes that determine overall resource use are medical management (treatments and consultation time) and referral rates. …”
Get full text

Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…In the 12 months after fracture, patients are at increased risk of cognitive and functional decline, admission to long-term care institutions and higher mortality. …”
Get full text

Clinical and cost-effectiveness of first contact physiotherapy for musculoskeletal disorders in primary care: the FRONTIER, mixed method realist evaluation by Nicola E Walsh, Alice Berry, Serena Halls, Rachel Thomas, Hannah Stott, Cathy Liddiard, Zoe Anchors, Fiona Cramp, Margaret E Cupples, Peter Williams, Heather Gage, Dan Jackson, Paula Kersten, Dave Foster, Justin Jagosh

“…Outcome measures were recorded at baseline, 3 and 6 months (primary end point) to track changes in pain and functioning using the Short Form questionnaire-36 items physical component summary (SF-36-PCS) primary outcome measure, and were compared across the care models. …”
Get full text