A novel model-based meta-analysis to indirectly estimate the comparative efficacy of two medications: an example using DPP-4 inhibitors, sitagliptin and linagliptin, in treatment o... by Yan Gong, James Rogers, Christian Friedrich, Sanjay Patel, Alexander Staab, Jorge Luiz Gross, Daniel Polhamus, William Gillespie, Brigitta Ursula Monz, Silke Retlich

“…Comparison of two oral dipeptidyl peptidase (DPP)-4 inhibitors, sitagliptin and linagliptin, for type 2 diabetes mellitus (T2DM) treatment was used as an example.Design Systematic review with MBMA.Data sources MEDLINE, EMBASE, http://www.ClinicalTrials.gov, Cochrane review of DPP-4 inhibitors for T2DM, sitagliptin trials on Food and Drug Administration website to December 2011 and linagliptin data from the manufacturer.Eligibility criteria for selecting studies Double-blind, randomised controlled clinical trials, ≥12 weeks’ duration, that analysed sitagliptin or linagliptin efficacies as changes in glycated haemoglobin (HbA1c) levels, in adults with T2DM and HbA1c >7%, irrespective of background medication.Model development and application A Bayesian model was fitted (Markov Chain Monte Carlo method). …”
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Whole blood RNA-seq analysis reveals the immunomodulatory effects of a supplemental multi-strain direct-fed microbial in the diet of newly weaned beef steers1 by Adekunle Ajiboye, Samanthia Johnson, Modoluwamu Idowu, Yarahy Leal, Taylor Sidney, Godstime Taiwo, Ibukun M. Ogunade, Christopher Ashwell

“…On day 56, 10 mL of blood was collected from 10 randomly selected beef steers from each treatment group prior to morning feeding. …”
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Willingness to participate in COVID-19 vaccine trials; a survey among a population of healthcare workers in Uganda. by Jonathan Kitonsa, Onesmus Kamacooko, Ubaldo Mushabe Bahemuka, Freddie Kibengo, Ayoub Kakande, Anne Wajja, Vincent Basajja, Alfred Lumala, Edward Ssemwanga, Robert Asaba, Joseph Mugisha, Benjamin F Pierce, Robin Shattock, Pontiano Kaleebu, Eugene Ruzagira

“…Using a standardised questionnaire, data were collected on socio-demographics, previous participation in health research, COVID-19 information sources, underlying health conditions, and willingness-to-participate in COVID-19 vaccine trials. …”
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Sensory integration research: priority scientific directions based on the analysis of Web of Science Core Collection resources by Olha Podrihalo, Wladyslaw Jagiello, Guo Xiaohong, Leonid Podrigalo, Tetiana Yermakova, Miroslawa Cieslicka

“…The bibliometric database Web of Science Core Collection (WoS) was analyzed. 388 sources that met the search criteria for 2013-2023 were selected for primary analysis. …”
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Persistence in the socio-economic development of the regions of the Siberian Federal District by Misak S. Arzumanyan

“…In the writings of management economists, the term «persistence» has not been mentioned before; there are no sources characterizing the degree of study of this phenomenon in relation to ensuring sustainable socio-economic development of territories. …”
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Distinct repertoires of microRNAs present in mouse astrocytes compared to astrocyte-secreted exosomes. by Ana Jovičić, Aaron D Gitler

“…<h4>Background</h4>Astrocytes are the most abundant cell type in the central nervous system (CNS) and secrete various factors that regulate neuron development, function and connectivity. microRNAs (miRNAs) are small regulatory RNAs involved in posttranslational gene regulation. …”
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High-quality reference genome decoding and population evolution analysis of prickly Sechium edule by Xiaojing Wang, Shaoqin Shen, Yanhong Fu, Rui Cao, Yunfeng Wei, Xiaoming Song

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An effective fluorescence strategy based on xanthine oxidase catalysis and the carbon dots’ specific response to ·OH for aminophylline pharmacokinetic studies by Chenfang Miao, Menghan Zhang, Ying Zheng, Xiaoyan Lin, Shuangying Yang, Linlin Xu, Sitong Lu, Zhengjun Huang, Jianyong Huang, Yanjie Zheng, Shaohuang Weng

“…In this study, high quantum yield carbon dots (CA/EDA-CDs) were synthesized via a hydrothermal method using riboflavin as the carbon source, citric acid and ethylenediamine as functionalizing agents and dopants. …”
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Effect of triclosan on phosphate solubilising bacteria in mangrove ecosystem: In-vitro and In-vivo by R.K. Dash, K. Kumar, S.P. Shukla, S. Kumar, S. Kumar H, S. Karmakar, T. Paul

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Prevalence and contributing factors of depression among women with infertility in low-resource settings: a systematic review and meta-analysis by Shimelis Tadesse, Henok Kumsa, Gemeda Wakgari Kitil, Alex Ayenew Chereka, Getnet Gedefaw, Fiker Chane, Esuyawkal Mislu

“…Subgroup and sensitivity analyses were performed to identify the potential source/s of heterogeneity. A p-value of 0.05 was declared as statistically significant. …”
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BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity by Eliana MC Tacconi, Xianning Lai, Cecilia Folio, Manuela Porru, Gijs Zonderland, Sophie Badie, Johanna Michl, Irene Sechi, Mélanie Rogier, Verónica Matía García, Ankita Sati Batra, Oscar M Rueda, Peter Bouwman, Jos Jonkers, Anderson Ryan, Bernardo Reina‐San‐Martin, Joannie Hui, Nelson Tang, Alejandra Bruna, Annamaria Biroccio, Madalena Tarsounas

“…Endogenous acetaldehyde, a product of cellular metabolism, is a potent source of DNA damage, particularly toxic to cells and mice lacking the FA protein FANCD2. …”
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ICP Enhancement Algorithm for 6D Pose Tracking of Household Objects by Hyunho Hwang, Hyunsoo Shin, Ji-Hun Bae, Sungon Lee

“…We estimate the initial pose using RGB keypoints and fine-tune the weights of the loss function to achieve an accurate pose by considering the flat and rotational symmetric properties of the object. …”
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Application of microscopic smartphone attachment for remote preoperative lab testing by Kefan Song, Kefan Song, Alexander T. Adams, Alexander T. Adams

“…This device is designed to assist both healthcare providers in resource-limited settings and patients by offering a low-cost, portable diagnostic tool that enables both in-clinic and at-home testing.MethodsThe system was tested for adaptability and compatibility by transitioning from its original Android platform to an iOS platform. …”
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Exploring the Medicinal Potential of <i>Taraxacum Kok-Saghyz</i> (<i>TKS</i>) Using Widely Targeted Metabolomics by Michele Tan, Jeffrey Shih-Chieh Chu, Daniel Robin Swiger

“…This study presents the first comprehensive metabolic profile of <i>TKS</i>, highlighting its potential value beyond rubber production. The detection of numerous therapeutic secondary metabolites supports its promise as a pharmaceutical and nutraceutical resource. …”
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Effects of Covid-19 Pandemic on School Dropout in Selected Primry Schools in Nyarusiza Sub-County Kisoro District. by Sibo, Dusabe Chris Jackson

“…Innovative approaches could be used such as applications of artificial intelligence in high-risk/high-traffic sites to enhance COVID-19 detection efficiency while protecting medical staff and the general public from cross-infections The government should establish a physical and automated platform for coordination and resource mobilization for support to the poor pupils and the most vulnerable groups affected by COVID-19-related lockdown.…”
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Prognostic value and immunotherapy analysis of immune cell-related genes in laryngeal cancer by Sen Zhang, Jianrui Pan, Huina Guo, Xiaoya Guan, Chenxu Yan, Lingling Ji, Xiansha Wu, Hui Huangfu

“…Key genes were identified through the intersection of differentially expressed genes (DEGs) between normal and LC samples and module genes derived from weighted gene co-expression network analysis (WGCNA), followed by functional enrichment analysis. The prognostic risk model was constructed using univariate Cox and Least Absolute Shrinkage and Selection Operator (LASSO) analyses. …”
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La teoría del rayo paraxial en la sismica de pozo: Aproximación de segundo orden en los tiempos de tránsito by Montes Vides Luis Alfredo

“…This characteristic VSP function can be numerically estimated using at least six measurements of appropriated selected travel times.…”
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Pretest probability of coronary artery disease as a factor for optimizing invasive diagnostics in routine clinical practice by M. A. Simonyan, T. Yu. Kalyuta, E. N. Genkal, O. M. Posnenkova, V. I. Gridnev

“…In 2017-2019, the number of detected CAD cases and proportion of men increased. …”
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Combined metabolome and transcriptome to analyze the regulatory network of key enzymes in the synthesis of senkirkine in Emilia sonchifolia by Jinli Yao, Yanqing Qin, Dongping Tu, Yumei Huang, Liuguan Liang, Wenhui Cai, Mingli Huang, Xiaoqi Zhu, Xinling Lao

“…This study provided references for gene functional expression analysis and laid a foundation for decoding the senkirkine biosynthesis pathway. …”
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CLSTM-MT (a Combination of 2-Conv CNN and BiLSTM Under the Mean Teacher Collaborative Learning Framework): Encryption Traffic Classification Based on CLSTM (a Combination of 2-Conv... by Xiaozong Qiu, Guohua Yan, Lihua Yin

“…The identification and classification of network traffic are crucial for maintaining network security, optimizing network management, and ensuring reliable service quality. These functions help prevent malicious activities, such as network attacks and illegal intrusions, while supporting the efficient allocation of network resources and enhancing user experience. …”
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