Potential physiological mechanisms behind variation in rainbow trout (Oncorhynchus mykiss) to biosynthesize EPA and DHA when reared on plant oil replacement feeds by Ken Overturf, Jason Abernathy, Dietmar Kültz, Jacob Bledsoe, Shawn Narum, Thomas Welker

“…The omega-3 fatty acids, docosahexaenoic acid (DHA; 22:6n-3) and eicosapentaenoic acid (EPA; 20:5n-3), are of primary concern as they provide significant health benefits such as reducing inflammation and improving heart and health function. However, the DHA; 22:6n-3 and EPA; 20:5n-3 available for aquaculture feeds is primarily provided by fish oil which is already limited in availability and expensive, and dietary lipids are consistently being replaced with oil sourced from plants. …”
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Distinct microbial communities drive methane cycling in below- and above-ground compartments of tropical cloud forests growing on peat by Fahad Ali Kazmi, Ülo Mander, Ramita Khanongnuch, Maarja Öpik, Reti Ranniku, Kaido Soosaar, Mohit Masta, Salla A. M. Tenhovirta, Kuno Kasak, Claudine Ah-Peng, Mikk Espenberg

“…However, no CH4-cycling functional genes were detected in the stem core samples. …”
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The cardiac phospho-proteome during pressure overload in mice by Rhys Wardman, Steve Grein, Jennifer Schwartz, Frank Stein, Joerg Heineke

“…Our analysis highlights significant changes in hypertrophic signalling, metabolic remodelling, contractile function, and the stress response pathways. We present proteomic data from the main cardiac cell types (endothelial cells, fibroblasts and cardiomyocytes) to reveal the cellular localisation of the detected phospho-proteins, offering insights into temporal and site-specific phosphorylation events, facilitating the potential discovery of novel therapeutic targets and biomarkers. …”
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Comprehensive analysis of complete chloroplast genome sequence of Morina L. by Peng-Hui Liu, Qing Yuan, Huan Liu, Le-Le Qin, Yao Wei, Xu-Min Li, Fei Ren, Xiao-Lei Ma, Hai-Rui Liu

“…This study is conducive to the development and utilization of the resources of Morina, and provides a theoretical basis for the further study of this species.…”
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Transcriptomic Analysis Reveals the Biosynthesis Mechanism of Coixol Under Salicylic Acid Treatment by Yao Wang, Hanli Ye, Xuqin Luo, Ziwei Li, Chuanqi Zheng, Dali Sun

“…Conclusions: These findings not only pointed the way for increasing the content of coixol in cultivation but also provided a reference for further elucidation of the gene functions involved in the bioaccumulation of coixol.…”
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Engineered hybrid cell membrane nanosystems for treating cardiovascular diseases by He Lu, Yaohui Jiang, Rui Luo, Dexing Zhou, Feihu Zheng, Liran Shi, He Zhang, Yong Wang, Xiaodong Xu, Renfang Zou, Yujing Zhou, Shuai Ren, Xiaocheng Wang, Haiqiang Sang

“…A significant benefit associated with this technology lies in its capacity to retain the functional and intrinsic properties of the source cells. …”
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Rossby Number Regime, Convection Suppression, and Dynamo-generated Magnetism in Inflated Hot Jupiters by Albert Elias-López, Matteo Cantiello, Daniele Viganò, Fabio Del Sordo, Simranpreet Kaur, Clàudia Soriano-Guerrero

“…We recover magnetic field strengths for inflated HJs by applying well-known scaling laws for fast rotators. When strong heat sources are applied mostly in the outer envelope and outside the dynamo region, as realistic ohmic models predict, convection in the dynamo region often breaks down. …”
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Hypoglycemic, Antioxidant Activities, and Probiotic Characteristics of <i>Lacticaseibacillus rhamnosus</i> LBUX2302 Isolated from Stool Samples of Neonates by Pedro A. Reyes-Castillo, Ana Laura Esquivel-Campos, Edgar Torres-Maravilla, Eduardo Zúñiga-León, Felipe Mendoza-Pérez, Rosa González-Vázquez, María Guadalupe Córdova-Espinoza, María Angélica Gutiérrez-Nava, Raquel González-Vázquez, Lino Mayorga-Reyes

“…Finally, the presence of ferulic acid activity was detected. The results highlight <i>L. rhamnosus</i> LBUX2302 as a promising probiotic with hypoglycemic and antioxidant effects, warranting further in vivo evaluation for its possible inclusion in functional food and health formulations.…”
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Celastrol-loaded ginsenoside Rg3 liposomes boost immunotherapy by remodeling obesity-related immunosuppressive tumor microenvironment in melanoma by Hongyan Zhang, Jingyi Huang, Yujie Li, Wanyu Jin, Jiale Wei, Ninghui Ma, Limei Shen, Mancang Gu, Chaofeng Mu, Donghang Xu, Yang Xiong

“…Obesity usually exacerbates the immunosuppressive tumor microenvironment (ITME), hindering CD8+ T cell infiltration and function, which further represents a significant barrier to the efficacy of immunotherapy. …”
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Assessing the Impact of Covid19-Pandemic on the Household Income in Kamuganguzi Sub-County Kabale District. by Arinda, Redeemer Present

“…Additionally, the government should establish a physical and automated platform for coordination and resource mobilization to support poor students and the most vulnerable groups affected by COVID-19-related lockdowns.…”
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Tradeoffs When Building and Running Cohort and Patient-Level Markov Simulation Models by Balázs Nagy, Ahmad Nader Fasseeh, Jonathan D. Campbell, Zoltán Kaló, Kareem Ahmed El-Fass, Rok Hren, Bertalan Németh

“…The CH and PL models yielded very similar base case results; only minor differences in functionality and outcome consistency were detected. …”
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Heritage in real life: between appreciation and contempt: why are modern Egyptians continuously losing their heritage? by Medhat Wassef

“…Being a part of the community myself and through direct contact with the people, I detected and extracted aspects of the Egyptian mindset on the grassroots level that played a significant role in the problem of heritage. …”
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Antioxidant potential of tree bark extracts: Insight from the multi-level output of the Antioxidant Power 1 assay. by Johanna Rehrl, Thomas Sepperer, Sissy Häsler Gunnarsdottir, Thomas Schnabel, Gertie Janneke Oostingh, Anja Schuster

“…Tree bark is a complex protective tissue that serves both physiological and defensive functions and is particularly rich in phenolic compounds bearing antioxidant, antimicrobial, anti-inflammatory and wound healing properties. …”
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Socioeconomic Inequity in Access to Medical and Long-Term Care Among Older People by Shohei Okamoto, Atsuhiro Yamada, Erika Kobayashi, Jersey Liang

“…Conclusion Improving the understanding of available resources and strengthening the functions of health centres and communities are required to detect the needs of citizens and facilitate their access to necessary care.…”
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Origami-Inspired Biosensors: Exploring Diverse Applications and Techniques for Shape-Changing Sensor Platforms by Shikha Patil, Shariq Suleman, Nigar Anzar, Jagriti Narang, Roberto Pilloton, Suna Timur, Emine Guler Celik, Chandra S. Pundir, Sudheesh K. Shukla

“…Paper and biological substrates like DNA have been integrated with origami techniques to develop biosensors with enhanced functionality. The incorporation of aptamer origami into both paper and DNA biosensors further increases sensitivity and specificity for target detection. …”
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Performance of the National Tuberculosis Control Program in the post conflict Liberia. by Kassaye Tekie Desta, T E Masango, Zerish Zethu Nkosi

“…For the performance of tuberculosis laboratory testing, all the 107 functional tuberculosis microscopy centers in Liberia were included. …”
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Diagnosing skin neglected tropical diseases with the aid of digital health tools: A scoping review. by Ewelina Julia Barnowska, Anil Fastenau, Srilekha Penna, Ann-Kristin Bonkass, Sophie Stuetzle, Ricky Janssen

“…Recent developments in digital health have given rise to approaches that could increase access to diagnosis in resource-poor areas affected by skin NTDs. This scoping review provides an overview of current digital health approaches that aim to aid in the diagnosis of skin NTDs and provides an insight into the diverse functionalities of current digital health tools, their feasibility, usability, and the current gaps in research around these digital health approaches. …”
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Quantification of glucagon and oxyntomodulin by protein precipitation-immunoaffinity enrichment-LC-MS/MS by Jessica O. Becker, Sara K. Shijo, Huu-Hien Huynh, Katrina L. Forrest, Michael J. MacCoss, Michelle A. Emrick, Elisha Goonatilleke, Andrew N. Hoofnagle

“…A glucagon calibration material was sourced commercially and characterized for purity and concentration by high-performance liquid chromatography-ultraviolet detection and amino acid analysis. …”
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Iodine deficiency as an environmental risk factor for thyroid gland diseases in animals by І. P. Ligomina, I. M. Sokulskyi, V. M. Sokolyuk, B. V. Gutyj, L. M. Soloviova

“…The situation is complicated in the biogeochemical zones of Ukraine, where insufficient or excessive content of mobile forms of microelements in soils and water sources determines the biological reaction of local flora and fauna. …”
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Estimation of bacterio‐, picophyto‐ and nanophytoplankton abundance in the Middle Caspian Sea by flow cytometry by V. S. Mukhanov, T. V. Rauen, S. V. Vostokov, A. S. Vostokova, E. N. Lobachev

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