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Lactylation: From Homeostasis to Pathological Implications and Therapeutic Strategies
Published 2025-06-01“…Moreover, we discuss advanced detection technologies and potential therapeutic interventions targeting lactylation pathways. …”
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1282
Genome-wide identification and expression analyses of CYP450 genes in Chrysanthemum indicum
Published 2025-05-01“…Conclusions The genome-wide analyses of cytochrome P450 superfamily offers essential genomic resources for functional studies of CiCYP450 genes, and is significant for the molecular breeding of Chrysanthemum.…”
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1283
A Novel Approach to Cognitive Load Measurement in N-Back Tasks Using Wearable Sensors, Empirical Mode Decomposition With Machine Learning, and Explainable AI for Feature Importance
Published 2025-01-01“…This study introduces a novel approach for detecting mental workload and stress, utilizing ECG and Fingertip-PPG data from the MAUS dataset. …”
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1284
Pseudomonas cold shock proteins suppress bacterial effector translocation in Nicotiana benthamiana
Published 2025-01-01Get full text
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1285
NORDIC denoising on VASO data
Published 2025-01-01“…However, VASO comes along with another reduction in detection sensitivity. NOise Reduction with DIstribution Corrected (NORDIC) PCA (principal component analysis) is a denoising technique specifically aimed at suppressing thermal noise, which has proven useful for increasing the SNR of high-resolution functional data. …”
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Comparative analysis of the gut microbiota composition among three captive hornbills
Published 2025-08-01“…The homogenization of food resources in a captive environment may weaken the impact of host differences on the gut microbiota. …”
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1288
Antibiotic Resistance and Virulence Determinants of <i>Pseudomonas aeruginosa</i> Isolates Cultured from Hydrocarbon-Contaminated Environmental Samples
Published 2025-03-01“…In some of these <i>P. aeruginosa</i> strains, loss-of-function mutations were detected in the regulatory genes <i>mexR</i>, <i>nalC</i>, or <i>nalD</i>, predicting an efflux-mediated acquired antibiotic-resistance mechanism. …”
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1289
Efficient analysis of drug interactions in liver injury: a retrospective study leveraging natural language processing and machine learning
Published 2024-12-01“…Electronic medical records contain comprehensive clinical information and have gained increasing attention as a potential resource for DDI detection. However, a substantial portion of adverse drug reaction (ADR) information is hidden in unstructured narrative text, which has yet to be efficiently harnessed, thereby introducing bias into the research. …”
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A data driven approach using local measurements to locate turbine governors causing forced oscillations
Published 2025-07-01“…When forced oscillations are detected, they are located by finding the transfer functions that describe the behaviour of the corresponding plant the worst. …”
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1293
Interrelation of indicators of oxygen metabolism of neutrophils and antiendotoxin immune as a marker of the postoperative period in patients with acute colonic obstruction
Published 2023-07-01“…The focus of purulent inflammation in the abdominal cavity serves as a source of concentration of antimicrobial mechanisms, among which the central role is played by neutrophilic granulocytes and factors cooperating with them. …”
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1294
Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy
Published 2025-02-01“…Then, downstream analyses were performed to detect protein interactions, gene function, cell type-specific expression and druggable information.Results: This study genetically predicted levels of 62 plasma proteins were associated with GD risk. …”
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1295
Impact of probiotic supplementation on serum levels of brain-derived neurotrophic factor: GRADE-based dose-response meta-analysis
Published 2025-08-01“…Abstract Background Brain-derived neurotrophic factor (BDNF) is a key neurotrophin involved in neuroplasticity and cognitive function, with its dysregulation linked to neurodegenerative and psychiatric disorders. …”
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1296
Proteinuria Ratio and Related Factors İn Type 2 DM Patients: A Hospital-Based Study in Somalia
Published 2025-02-01“…Understanding these factors is crucial for early detection and intervention to prevent kidney damage in this population. …”
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1297
A UAV Image Stitching Method for Complex Urban Environments
Published 2025-07-01Get full text
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1298
Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation
Published 2025-05-01“…This study aimed to clarify the roles of mitochondrial metabolism and immune infiltration in MI, using a combination of bioinformatics analyses and experimental validation.MethodsMI chip data (GSE96561, GSE181872, and GSE183272) were obtained from the Gene Expression Omnibus (GEO) database, and mitochondrial gene data were sourced from the MitoCarta3.0 database. Differentially expressed genes (DEGs) were identified and subjected to functional enrichment analyses. …”
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Untargeted Metabolomics Reveals Distinct Anthocyanin Profiles in Napier Grass (<i>Pennisetum purpureum</i> Schumach.) Cultivars
Published 2025-07-01“…Plant secondary metabolites regulate plant growth and serve as valuable pharmaceutical resources. Napier grass (<i>Pennisetum purpureum</i> Schumach.), a Poaceae species, shows potential as a functional food. …”
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