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3501
Unlocking liver physiology: comprehensive pathway maps for mechanistic understanding
Published 2025-07-01“…In this study, we introduce two Liver Physiological Maps (PMs); comprehensive and machine-readable graphical representations of the intricate mechanisms governing two major liver functions.MethodsTwo PMs were developed through manual literature curation, integrating data from established pathway resources and domain expert knowledge. …”
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3502
Establishing a core outcome set for creatine transporter deficiency and guanidinoacetate methyltransferase deficiency
Published 2025-08-01“…Conclusions Development of this COS illustrates a patient-centered approach for clinical trial readiness for CTD and GAMT that if utilized will make clinical trial results comparable, minimize bias in clinical trial outcome selection, and promote efficient use of resources.…”
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3503
Cylindrospermopsin adsorption onto activated carbons synthesized from coconut shell: Effect of surface chemical composition on removal efficiency
Published 2024-08-01“…Cylindrospermopsin (CYN) is a toxic metabolite globally documented in aquatic environments, including human supply water sources. Adsorption onto activated carbon (AC) has emerged as a promising and cost-effective advanced technique to remove this cyanotoxin in water treatment utilities. …”
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3504
Soft Skills for Employment in Morocco: A Value Over or Equal to the Technical Know-how?
Published 2024-02-01“…This study is an exploratory endeavor that utilizes secondary data sources from scientific journals and administers questionnaires to teachers, enterprise managers, and students to unveil their attitudes in the Moroccan context. …”
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3505
Serbian diplomacy in deterrence
Published 2023-01-01“…The goal of this paper is, relying on a realistic theoretical foundation, to provide an analysis of diplomatic functions and examine its significance for effective deterrence and the necessity of synchronized action with other foreign policy instruments; instruments that were primarily developed for deterrence but can be utilized differently if diplomacy fails to navigate the security dilemma's failings.…”
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3506
Examining the Role of Religion in Increasing the Quality of Life of Women in the Muslim World in the Tanggulangin, Sidoarjo
Published 2025-06-01“…Employing a qualitative methodology, the study utilizes a diverse array of scholarly sources, case studies, and empirical data to explore the complex relationship between Islamic principles and the evolving roles of women. …”
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3507
Bioprospecting the Endophytic Fungus, <i>Lasiodiplodia theobromae</i> MMPI, for the Integrated Production of Mycoprotein and Exocellular (1→6)-β-Glucan
Published 2025-03-01“…In response to the growing demand for alternative protein sources and functional biomolecules for industrial applications, this study investigated the production of mycoprotein and extracellular (1→6)-β-D-glucan (lasiodiplodan) by the fungus <i>Lasiodiplodia theobromae</i> MMPI, establishing an integrated biotechnological platform. …”
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3508
Engineered microbial platform confers resistance against heavy metals via phosphomelanin biosynthesis
Published 2025-05-01“…However, there exists a vast urgency to optimize these engineered microbial platforms, which will amplify their protective capabilities, integrate multifaceted functions, and thereby expand their utility and effectiveness. …”
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3509
Transforming non-conventional yeasts into key players in biotechnology: advances in synthetic biology applications
Published 2025-05-01“…Beyond the conventional yeast Saccharomyces cerevisiae, non-conventional yeasts are naturally more multifaceted, possessing the ability to utilize renewable and low-cost carbon sources while exhibiting robust physiology under challenging conditions. …”
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3510
Identification of heterogeneity and common characteristics in colorectal carcinoma located in distinct sites
Published 2025-07-01“…We isolated 344 tumor and 54 normal cases spanning seven locations: sigmoid, ascending, caecum, rectum, transverse, descending, and recto-sigmoid. Cell biological functions were assessed utilizing CCK8, EdU assays, Transwell assays, and wound healing assays. …”
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3511
A novel and rapid method to purify the human complement opsonin C3b from human plasma
Published 2025-08-01“…C3b has several important functions and remains a focus of basic and translational research. …”
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3512
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3513
Research dynamics and frontier trends of orogenic gold deposits: a knowledge map based on bibliometrics
Published 2025-07-01“…Orogenic gold deposits represent a vital component of global gold reserves, functioning as both significant sources of gold and essential indicators for understanding crustal metallogeny within collisional tectonic environments. …”
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3514
Advanced Microfluidic Biofuel Cells Using Gold and Silver Leaf on Paper and PDMS Substrates: Toward Implantable Energy Solution
Published 2025-01-01“…An exploration of new and simplified electrode materials such as gold leaf (GL), and silver leaf (SL) based approaches to enhance the efficiency and scalability of microfluidic biofuel cell renewable energy sources has generated significant interest. Our research aims to utilize the unique properties of these materials to create advanced biofuel cells, with a specific focus on implantable devices. …”
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3515
EnGCI: enhancing GPCR-compound interaction prediction via large molecular models and KAN network
Published 2025-05-01“…Large molecular models, due to their ability to capture detailed structural and functional information, have shown promise in enhancing the predictive accuracy of downstream tasks. …”
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3516
Development and optimization of a neural network model using genetic algorithm to predict the performance of a packed bed reactor treating sulphate-rich wastewater
Published 2024-12-01“…Using genetic algorithm (GA) with appropriate objective functions, optimal sets of inputs were obtained to ensure maximum RE at a minimum HRT. …”
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3517
Multi-Timescale Nested Hydropower Station Optimization Scheduling Based on the Migrating Particle Whale Optimization Algorithm
Published 2025-04-01“…Validation on classical test functions and the Jiangpinghe River of the multi-timescale nested optimal scheduling model demonstrates that MPWOA exhibits faster convergence and stronger optimization capabilities and significantly improves power generation. …”
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3518
Japanese Family Conditions Demonstrating Family Resilience: Directed Content Analysis Based on Literature and Family Interviews
Published 2025-03-01“…<b>Background/Objectives:</b> When experiencing a variety of negative family events, families that, as a whole, have high family resilience maintain and improve family functioning. It is important, therefore, for nursing professionals to be able to assess families lacking in family resilience in order to prevent, reduce, or ameliorate family symptoms (such as family-perceived problems, issues, difficulties, or suffering). …”
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3519
Stacked ensemble model for accurate crop yield prediction using machine learning techniques
Published 2025-01-01“…Historically, such predictions have utilized diverse data sources, including agricultural, land, climatic, atmospheric, and other pertinent information. …”
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3520
Ismāʿīlī - Fāṭimid Legal Education and Judicial Activities in Egypt
Published 2025-06-01“…During the literature review conducted, Ismāʿīlī sources were utilized, benefiting from both primary and secondary sour-ces. …”
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