Levels of amino acids and homoarginine in the venous basins of the brain and the heart muscle in patients with ischemic heart disease by N. S. Molchan, T. Yu. Reypol'skaya, T. F. Subbotina, A. A. Zhloba, Yu. S. Polushin

“…Under the conditions of circulatory disorders and coronary heart disease (CHD), amino acids acquire additional value as a source of intermediates of Krebs cycle, participating in cell energetics. …”
Get full text

Enzymatic system of glucose metabolism in Gluconobacter oxydans strain DHA3-9 by Li Qianyan, Lu Xiangfeng, Zhang Pengcheng, Sun Lingyan, Liu Yu, Ma Xiaohang

“…Pyruvate and acetate were detected in the products of mutant whereas none of such products were found in wild type culture. …”
Get full text

ROS and cGMP signaling modulate persistent escape from hypoxia in Caenorhabditis elegans. by Lina Zhao, Lorenz A Fenk, Lars Nilsson, Niko Paresh Amin-Wetzel, Nelson Javier Ramirez-Suarez, Mario de Bono, Changchun Chen

“…The ability to detect and respond to acute oxygen (O2) shortages is indispensable to aerobic life. …”
Get full text

Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells. by Ryan D Huff, Alan C-Y Hsu, Kristy S Nichol, Bernadette Jones, Darryl A Knight, Peter A B Wark, Philip M Hansbro, Jeremy A Hirota

“…<h4>Introduction</h4>The airway epithelium is a physical and immunological barrier that protects the pulmonary system from inhaled environmental insults. Uric acid has been detected in the respiratory tract and can function as an antioxidant or damage associated molecular pattern. …”
Get full text

Experimental Study of Coherent Collaborative Processing Method in Distributed Automotive Radar by A. A. Kuzin, S. E. Kuznetsov, A. V. Miakinkov, R. S. Fadeev, S. A. Shabalin

“…Intelligent driver assistance systems are increasingly employing radar systems to detect, resolve, and track various classes of targets. …”
Get full text

Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis. by Pei-Hsuan Weng, Yi-Ling Huang, John H Page, Jen-Hau Chen, Jianfeng Xu, Stella Koutros, Sonja Berndt, Stephen Chanock, Meredith Yeager, John S Witte, Rosalind A Eeles, Douglas F Easton, David E Neal, Jenny Donovan, Freddie C Hamdy, Kenneth R Muir, Graham Giles, Gianluca Severi, Jeffrey R Smith, Carmela R Balistreri, Irene M Shui, Yen-Ching Chen

“…<h4>Background</h4>Toll-like receptor 4 (TLR4) is one of the best known TLR members expressed on the surface of several leukocytes and tissue cells and has a key function in detecting pathogen and danger-associated molecular patterns. …”
Get full text

A juxtamembrane basolateral targeting motif regulates signaling through a TGF-β pathway receptor in Drosophila. by Aidan J Peterson, Stephen J Murphy, Melinda G Mundt, MaryJane Shimell, Edward B Leof, Michael B O'Connor

“…We also show that apicalized Punt does not produce an ectopic signal, indicating that the apical pool of Dpp is not a significant signaling source even when presented with Punt. Instead, we find that basolateral presentation of Punt is required for optimal signaling. …”
Get full text

Intercropping and Nitrogen Fertilization Altered the Patterns of Leaf Senescence in Sorghum by Peter E. Moi, Onesmus M. Kitonyo, George N. Chemining’wa, Josiah M. Kinama

“…Effects of competition in sorghum-legume intercropping and source-sink relationships on the patterns of leaf senescence deserve further investigation.…”
Get full text

Evolutionary game of multimodal transport organization considering the new airport operation: Taking Beijing Daxing International Airport for an example by Xiaoping Wang, Chang Cao, Jiahui Chen, Yating Wu

“…The focus is on their collaborative strategies to establish a functional multimodal transport cooperation mechanism. …”
Get full text

Exploring structural and biological insights of TEAD through rational design and synthesis of niflumic acid derivatives by Yong-Sung Choi, Yoon-Jung Kim, Yeram Jeon, Jong Soon Kang, Juhee Lee, Eunmi Hong, Young-Hoon Park, Wantae Kim, Boksik Cha, Raok Jeon

Get full text

Cost-effectiveness of prehabilitation prior to elective surgery compared to usual preoperative care: protocol for a systematic review of economic evaluations by Tanja Rombey, Helene Eckhardt, Wilm Quentin

“…Introduction Preoperative functional capacity is an important predictor of postoperative outcomes. …”
Get full text

Otimização do uso da água no perímetro irrigado do Gorutuba, utilizando-se a técnica da programação linear Optimization of water use in the Gorutuba irrigation district, Minas Gera... by Daniel Fonseca de Carvalho, Antônio Alves Soares, Carlos Antônio Alvares Soares Ribeiro, Gilberto C. Sediyama, Fernando Falco Pruski

“…<br>This research was developed with the objective of selecting the crops and planting dates in order to maximize the farmers income and the water resources in the Gorutuba Irrigation District. …”
Get full text

Compost amendments up to one inch restore dry rangeland soil health by Eva Stricker, Emily Cornell, Zach Withers

“…Our results provide guidance for land stewards to assess their resources and management goals to optimize compost addition to build rangeland soil health.…”
Get full text

Assessing rehabilitation potential of the masticatory musculature in patients with temporomandibular myofascial pain syndrome: A randomized prospective controlled study by E. N. Iarygina, V. V. Shkarin, Yu. A. Makedonova, S. V. Dyachenko

“…Background. Selecting therapy for temporomandibular myofascial pain syndrome must be carefully justified, since functional impairments may be compensated and acceptable for the patient. …”
Get full text

Canada goose fecal microbiota correlate with geography more than host‐associated factors by Joshua C. Gil, Heather R. Skeen, Celeste Cuellar, Sarah M. Hird

“…This work also suggests that there is a minimum geographic distance, likely associated with sufficient variation in habitat, climate, and local food sources, that must be reached before significant differences in the microbiota between two populations can be detected.…”
Get full text

Synthesis of Molecularly Imprinted Polymers for Selective Extraction Followed by Solid Phase Determination of Metformin in Pharmaceutical Preparation and in Human Serum by Rana A. Kamal Aldeen, Yehya K. Al-Bayati

“…A solid-phase extraction (SPE) syringe packed with molecular imprinted polymers (MIPs) was employed to selectively separate and pre-concentrate the Metformin in multiple pharmaceutical drugs from several sources. The human serum was based on the use of deionized water to dilute the serum, followed by the heating of the serum with methanol. …”
Get full text

Strain Monitoring of Vertical Axis Wind Turbine Tower Using Fiber Bragg Gratings by Bastien Van Esbeen, Valentin Manto, Damien Kinet, Corentin Guyot, Christophe Caucheteur

“…Afterwards, by using power spectral density (PSD) on the strain signals, three sources of tower oscillations are discovered: wind force, structure unbalance, and 1st tower mode resonance, each with its intrinsic frequency. …”
Get full text

Peripheral immune cell dysregulation following diffuse traumatic brain injury in pigs by Kathryn L. Wofford, Kevin D. Browne, David J. Loane, David F. Meaney, D. Kacy Cullen

“…Indeed, secondary infections following TBI worsen neurological outcomes and are a major source of mortality and morbidity. Despite the compelling link between the damaged brain and peripheral immune functionality, little is known about how injury severity affects the peripheral immune system in closed-head diffuse TBI, the most common clinical presentation including all concussions. …”
Get full text

Assessing the impact of a rare synonymous variant in the <i>KNG1</i> gene on the development of hereditary angioedema by N. A. Pechnikova, Yu. V. Ostankova, M. A. Saitgalina, A. M. Bebyakov, A. A. Totolian

“…Therefore, (1) the mutant high-molecular-weight kininogen is more easily activated by kallikrein and becomes a source of bradykinin formation through the kallikrein-kinin system; (2) the mechanism of bradykinin formation undergoes significant changes and results in the formation of functionally active but aberrant bradykinin, which alters its inactivation by enzymes with a consequent increase in its half-life, (3) the changes in positions 380-389 bring about modifications in Lys-bradykinin reproduction such that in subsequent steps it is “easily” cleaved to bradykinin by arginine aminopeptidase. …”
Get full text

Fuzzy Modeling to Predict Severely Depressed Left Ventricular Ejection Fraction following Admission to the Intensive Care Unit Using Clinical Physiology by Rúben Duarte M. A. Pereira, Cátia M. Salgado, Andre Dejam, Shane R. Reti, Susana M. Vieira, João M. C. Sousa, Leo A. Celi, Stan N. Finkelstein

“…Left ventricular ejection fraction (LVEF) constitutes an important physiological parameter for the assessment of cardiac function, particularly in the settings of coronary artery disease and heart failure. …”
Get full text