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Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation
Published 2025-05-01“…This study aimed to clarify the roles of mitochondrial metabolism and immune infiltration in MI, using a combination of bioinformatics analyses and experimental validation.MethodsMI chip data (GSE96561, GSE181872, and GSE183272) were obtained from the Gene Expression Omnibus (GEO) database, and mitochondrial gene data were sourced from the MitoCarta3.0 database. Differentially expressed genes (DEGs) were identified and subjected to functional enrichment analyses. …”
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2202
Co-design and prototype development of MedManageSCI: a medication self-management toolkit for adults with spinal cord injury/dysfunction
Published 2025-04-01“…The implications of this work extend beyond SCI/D, highlighting the importance of tailored digital health resources for populations with complex healthcare needs. …”
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2203
INTERNATIONAL TECHNICAL AID IN POST-CONFLICT RECOVERY: LESSONS FROM GLOBAL PRACTICES FOR DE-OCCUPIED AREAS
Published 2025-07-01“…ITA is conceptualized as a strategic resource that encompasses financial, technical, expert, and institutional support from international donors aimed at the implementation of long-term sustainable development programs. …”
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2204
Preparation of PET matrix gradient composite fiber membrane for coal mine and Study on the dust filtration-moisture permeability
Published 2025-02-01“…And polyvinyl pyrrolidone was selected to regulate the hydrophilic gradient and improve the moisture permeability. …”
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2205
Feasibility and challenges in sustaining a community based surveillance system in post-Ebola Sierra Leone
Published 2024-11-01“…The most important costs drivers were training of CHWs (59% of total costs) and salaries (including stipends of the CHWs) of human resources (15%). Barriers included sustainable financing of human resources, internet connectivity, as well as limited trainings and supportive supervision, and unsupported transportation costs for CHWs and peer supervisors (PS). …”
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2206
Implementation of hospital antimicrobial stewardship programmes in low- and middle-income countries: a qualitative study from a multi-professional perspective in the Global-PPS net...
Published 2025-04-01“…Four themes influenced AMS implementation, “institutional support and resource allocation”, “AMS team functioning, roles, and expertise”, “adoption and integration of AMS recommendations”, and “data-driven decision-making” as a cross-cutting theme. …”
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2207
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2208
Exploratory integration of near-infrared spectroscopy with clinical data: a machine learning approach for HCV detection in serum samples
Published 2025-06-01“…BackgroundManaging chronic viral infections like Hepatitis C virus (HCV) often requires expensive healthcare resources and highly qualified personnel, making efficient diagnostic methods essential. …”
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2210
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2211
Influência de um protocolo de criopreservação no rendimento in vitro de células-tronco derivadas do tecido adiposo Effect of a cryopreservation protocol on the in vitro yield of ad...
Published 2012-09-01“…<br>BACKGROUND: Adipose tissue obtained by liposuction may be an accessible source of stem cells for future clinical application in tissue regeneration. …”
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2212
SOURCES OF FINANCING INDUSTRIAL COMPLEX ENTERPRISES
Published 2016-08-01“…In the first part of the article provides an overview of the financial resources and types of funding organizations and enterprises. …”
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2213
JWST/NIRCam Narrowband Survey of Paβ Emitters in the Spiderweb Protocluster at z = 2.16
Published 2024-01-01“…The weight-corrected color–magnitude diagram obtained 57 sources showing narrowband excesses, 41 of which satisfy further color selection criteria for limiting the sample to Pa β emitter candidates at z ∼ 2.16, and 24 of them do not have H α emitter counterparts. …”
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2214
Evaluating the level of digitalization of the innovation process with artificial intelligence approach in the digital transformation of knowledge-based companies
Published 2025-02-01“…In this method, the number of membership functions is 5 functions representing very low, low, medium, high and very high. …”
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2215
HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer
Published 2025-08-01“…Human endogenous retroviruses (HERVs) are aberrantly expressed by tumor cells and may represent a source of shared T-cell epitopes for cancer immunotherapy regardless of the tumor mutational burden.Methods A transcriptomic analysis based on RNA sequencing was developed to quantify the expression of HERV-K sequences containing the selected epitopes. …”
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2216
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2217
Optimal Coordinated Flood Control Scheduling of Three Gorges and Qingjiang Cascade Reservoirs
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2218
Regulation of plant gene expression by tsRNAs in response to abiotic stress
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2219
Assessment of Aerodynamic Properties of the Ventilated Cavity in Curtain Wall Systems Under Varying Climatic and Design Conditions
Published 2025-07-01“…Ultimately, a correct understanding of thermophysical processes in such structures will support the advancement of trends such as Lightweight Design, Functionally Graded Design, and Value Engineering in the development of curtain wall systems, through the optimized selection of façade configurations, accounting for temperature loads under specific climatic and design conditions.…”
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2220
Network and systems biology approaches help investigate gene regulatory interactions between Salmonella disease and host in chickens: Model‐based in silico evidence combined with g...
Published 2024-11-01“…To start, we used free computational tools and online bioinformatics resources, including predicting gene function using a multiple association network integration algorithm (geneMania), the Kyoto Encyclopedia of Genes and Genomes, the Annotation, Visualization and Integrated Discovery (DAVID) database and the stimulator of interferon genes. …”
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