Systematic identification and characterization of high efficiency Cas9 guide RNAs for therapeutic targeting of ADAR. by Benjamin G Gowen, Kory Melton, Weng In Leong, Prachi Khekare, Shannon McCawley, Jean Chan, Pierre Boivin, Vihasi Jani, Aaron J Cantor, Akshay Tambe, Mary Haak-Frendscho, Mary J Janatpour, Spencer C Wei

“…These findings provide a resource of well-characterized, high efficiency ADAR-targeting Cas9 guide RNAs suitable for genomic medicines utilizing different delivery modalities and addressing different therapeutic areas.…”
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Advanced Monte Carlo for Acquisition Sampling in Bayesian Optimization by Javier Garcia-Barcos, Ruben Martinez-Cantin

“…Optimizing complex systems usually involves costly and time-consuming experiments, where selecting the experiments to perform is fundamental. …”
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ABOUT OF THE ASSIGNING APPEARANCES TO LOCOMOTIVE CREWS by Sergey P. Vakulenko, Aleksey V. Kolin, Airat M. Nasybullin, Liliya R. Aysina

“…This optimization could improve the planning of labor resource availability with a longer-term perspective. …”
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The Interface Between Innovation and Entrepreneurship with Strategic Risks and the Budget in a Brazilian Agribusiness Company by Thiago Bruno de Jesus Silva, Carlos Eduardo Facin Lavarda

“… In the context of Resource-based Theory (rbt), management control components such as budgeting play a crucial role in organizing and maximizing the potential of resources and capabilities. …”
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Tracking teachers’ experience of adopting my English step to infuse differentiated instruction by Ilza Mayuni, Yinghui Chen, Ni Made Ratminingsih, Tara Mustikaning Palupi, Nurhasanah Halim

“…This digital educational resource can be modified and adhered to its contextual connection. …”
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LatentDE: latent-based directed evolution for protein sequence design by Thanh V T Tran, Nhat Khang Ngo, Viet Thanh Duy Nguyen, Truong-Son Hy

“…Directed evolution (DE) has been the most effective method for protein engineering that optimizes biological functionalities through a resource-intensive process of screening or selecting among a vast range of mutations. …”
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Influence of Emergent Vegetation Layout on Flow Pattern in a Rectangular Shallow Basin by Junnan LYU, Yuxuan JIANG, Zhidong YAO, Chen YE, Xufeng YAN

“…They play critical roles in ecology, water resource management, environmental protection, and enhancing landscape aesthetics. …”
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Optimal Dispatch of Power System with P2G-Wind-Thermal-Nuclear-Carbon Capture Units by Wenhao CHAO, Zhi YUAN, Ji LI

“…Finally, the minimization of system comprehensive operation costs is selected as the overall objective function. At the same time, the carbon trading mechanism is considered to build the simulation model on the Matlab platform to verify the effectiveness of the proposed model. …”
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Bioremediation Potential of <i>Rhodococcus qingshengii</i> PM1 in Sodium Selenite-Contaminated Soil and Its Impact on Microbial Community Assembly by Mu Peng, Guangai Deng, Chongyang Hu, Xue Hou, Zhiyong Wang

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Prospects for using soft processors in systems-on-a-chip based on field-programmable gate arrays by I. E. Tarasov, D. S. Potekhin, O. V. Platonova

“…., processors based on configurable logical resources, for implementing control functions in an FPGA-based SoC.Methods. …”
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Application of evolutionary algorithm in estimation of environmental performance in farm systems by Srđan Jović, Dalibor Radovanović, Dušan Marković

“…Evolutionary algorithm (EA) can be employed in these problems because they can simultaneously focus on two or more objective functions. Multi-objective genetic algorithm (MOGA) as one of the EAs was selected and wheat as one of the most important strategic crops was chosen in order to test the application of these algorithms in farm systems. …”
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Analysis of the Soil Microbiome of a Los Angeles Urban Farm by Savanah St. Clair, Maryam Saraylou, Daila Melendez, Norman Senn, Serina Reitz, Destini Kananipour, Angelo Alvarez

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Can carbon-labeled food shift Vietnamese consumers towards greener consumption? Integrating theory of consumption value and theory of planned behavior by Huu-Dung Nguyen, Bui Duc Tho, Linh Hoang Thi My, Ha Nguyen Thu, Ngoc Trinh Bao, Anh Nguyen Tuan

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Principles for determining effective parameters for organizing train traffic in suburban-urban traffic, taking into account the differentiation of service classes by A. F. Borodin, I. F. Mustafin, K. Yu. Nikolaev

“…Relevant constraints for the task, due to the resources of the railway infrastructure and rolling stock, have been determined. …”
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Therapeutic Strategies for Dry Mouth Management with Emphasis on Electrostimulation as a Treatment Option by Amela Tulek, Aida Mulic, Martine Hogset, Tor Paaske Utheim, Amer Sehic

“…The aim of this study was to give an overview of the latest and most relevant data related to treatment modalities for the management of dry mouth conditions. Data Resources and Study Selection. The present review was prepared by searching the National Library of Medicine database using the relevant medical terms and their combinations. …”
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ECONOMIC ASPECTS OF ORGANIC SOY PRODUCTION IN UKRAINE by Hanna Pantsyreva

“…Consequently, the substantiation of its agrobiological potential in selected areas of sustainable production on non-irrigated land will ensure the territorial transformation of the "soybean belt". …”
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Business Ecosystem Finance: Modern Agenda and Challenges by I. M. Stepnov, J. A. Kovalchuk

“…The objectives of this research are defined as clarifying the need to include financing functions in the toolkit of emerging industrial business ecosystems and revealing the possibilities of using selected financing methods. …”
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Genome-Wide Identification of the SMXL Gene Family in Common Wheat and Expression Analysis of TaSMXLs Under Abiotic Stress by Zunjie Wang, Zhengning Jiang, Heping Wan, Xueyan Chen, Hongya Wu

“…This study provides a theoretical foundation for understanding the functional roles of <i>SMXL</i> genes in wheat and offers valuable candidate gene resources for breeding stress-resistant wheat varieties.…”
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Correction of Disturbances Influence on Results of Elongated Objects's Probe Microscopy Using Predictive Relief Estimates by P. V. Gulyaev

“…The formation of predictive images enhances the sharpness of objects and increases the probability of their correct selection using methods based on the analysis of changes in the brightness function.…”
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Implementation of a wireless sensor network for irrigation management in drip irrigation systems by Mehmet Kamil Meriç

“…The hardware and software designs of the soil moisture monitoring and valve control nodes were created, including the selection of components, specific functionalities of software algorithms, and communication protocols used for data transmission. …”
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